Different mechanisms of homologous and heterologous μ-opioid receptor phosphorylation.

PubWeight™: 0.84‹?›

🔗 View Article (PMID 24517854)

Published in Br J Pharmacol on July 01, 2014

Authors

Anika Mann1, Susann Illing, Elke Miess, Stefan Schulz

Author Affiliations

1: Institute of Pharmacology and Toxicology, Jena University Hospital, Friedrich-Schiller-University, Jena, Germany.

Articles cited by this

Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science (1992) 12.18

Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacol Rev (2001) 6.50

The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors. Br J Pharmacol (2013) 5.74

G protein-coupled receptor kinases. Annu Rev Biochem (1998) 5.53

Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization. Science (1996) 4.38

The role of receptor kinases and arrestins in G protein-coupled receptor regulation. Annu Rev Pharmacol Toxicol (1998) 3.87

Molecular mechanisms of receptor desensitization using the beta-adrenergic receptor-coupled adenylate cyclase system as a model. Nature (1985) 3.74

Neuroscience of addiction. Neuron (1998) 3.60

Molecular and cellular basis of addiction. Science (1997) 3.57

Cellular and synaptic adaptations mediating opioid dependence. Physiol Rev (2001) 3.45

Functional dissociation of mu opioid receptor signaling and endocytosis: implications for the biology of opiate tolerance and addiction. Neuron (1999) 3.15

Role for G protein-coupled receptor kinase in agonist-specific regulation of mu-opioid receptor responsiveness. Proc Natl Acad Sci U S A (1998) 3.07

Opioid receptors. Annu Rev Biochem (2004) 2.71

Opioids and the management of chronic severe pain in the elderly: consensus statement of an International Expert Panel with focus on the six clinically most often used World Health Organization Step III opioids (buprenorphine, fentanyl, hydromorphone, methadone, morphine, oxycodone). Pain Pract (2008) 2.45

Agonist-selective mechanisms of GPCR desensitization. Br J Pharmacol (2007) 2.17

Cellular neuroadaptations to chronic opioids: tolerance, withdrawal and addiction. Br J Pharmacol (2008) 1.99

75 years of opioid research: the exciting but vain quest for the Holy Grail. Br J Pharmacol (2006) 1.91

Agonist-selective mechanisms of mu-opioid receptor desensitization in human embryonic kidney 293 cells. Mol Pharmacol (2006) 1.87

Mu opioid receptor phosphorylation, desensitization, and ligand efficacy. J Biol Chem (1997) 1.86

μ-opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalization. Mol Pharmacol (2010) 1.83

Opioids: cellular mechanisms of tolerance and physical dependence. Curr Opin Pharmacol (2005) 1.82

Morphine induces terminal micro-opioid receptor desensitization by sustained phosphorylation of serine-375. EMBO J (2004) 1.77

Role of receptor internalization in opioid tolerance and dependence. Pharmacol Ther (2007) 1.66

Mu-opioid receptor desensitization: is morphine different? Br J Pharmacol (2004) 1.64

Heterodimerization of somatostatin and opioid receptors cross-modulates phosphorylation, internalization, and desensitization. J Biol Chem (2002) 1.54

Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis. BMC Genomics (2011) 1.49

Phosphorylation of Ser363, Thr370, and Ser375 residues within the carboxyl tail differentially regulates mu-opioid receptor internalization. J Biol Chem (2001) 1.46

Heterodimerization and cross-desensitization between the mu-opioid receptor and the chemokine CCR5 receptor. Eur J Pharmacol (2004) 1.45

Protein kinases modulate the cellular adaptations associated with opioid tolerance and dependence. Brain Res Brain Res Rev (2001) 1.44

Agonist-selective patterns of µ-opioid receptor phosphorylation revealed by phosphosite-specific antibodies. Br J Pharmacol (2011) 1.40

Heterodimerization of substance P and mu-opioid receptors regulates receptor trafficking and resensitization. J Biol Chem (2003) 1.40

Protein kinase C activation enhances morphine-induced rapid desensitization of mu-opioid receptors in mature rat locus ceruleus neurons. Mol Pharmacol (2004) 1.39

Role of protein kinase C and mu-opioid receptor (MOPr) desensitization in tolerance to morphine in rat locus coeruleus neurons. Eur J Neurosci (2009) 1.34

Regulated endocytosis of opioid receptors: cellular mechanisms and proposed roles in physiological adaptation to opiate drugs. Curr Opin Neurobiol (2003) 1.31

Under siege: The brain on opiates. Neuron (1996) 1.26

Quantitative encoding of the effect of a partial agonist on individual opioid receptors by multisite phosphorylation and threshold detection. Sci Signal (2011) 1.25

Differential mu opiate receptor phosphorylation and desensitization induced by agonists and phorbol esters. J Biol Chem (1996) 1.23

G protein-coupled receptor adaptation mechanisms. Semin Cell Dev Biol (1998) 1.15

A review of the use of fentanyl analgesia in the management of acute pain in adults. Anesthesiology (1999) 1.14

Deciphering µ-opioid receptor phosphorylation and dephosphorylation in HEK293 cells. Br J Pharmacol (2012) 1.13

Analysis of opioid efficacy, tolerance, addiction and dependence from cell culture to human. Br J Pharmacol (2011) 1.07

Differentiation of opioid drug effects by hierarchical multi-site phosphorylation. Mol Pharmacol (2012) 1.04

Analgesic tolerance to high-efficacy agonists but not to morphine is diminished in phosphorylation-deficient S375A μ-opioid receptor knock-in mice. J Neurosci (2011) 1.00

Protein kinase C-mediated phosphorylation of the μ-opioid receptor and its effects on receptor signaling. Mol Pharmacol (2011) 0.97

Identification of phosphorylation sites in the COOH-terminal tail of the μ-opioid receptor. J Neurochem (2012) 0.93

GRK2 protein-mediated transphosphorylation contributes to loss of function of μ-opioid receptors induced by neuropeptide FF (NPFF2) receptors. J Biol Chem (2012) 0.88

Heterologous regulation of agonist-independent μ-opioid receptor phosphorylation by protein kinase C. Br J Pharmacol (2014) 0.85

Articles by these authors

The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia. Cell (2010) 3.83

MEDSYNDIKATE--a natural language system for the extraction of medical information from findings reports. Int J Med Inform (2002) 2.70

CXCR4 regulates interneuron migration in the developing neocortex. J Neurosci (2003) 2.44

Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance. Pharmacol Rev (2013) 2.42

Receptor endocytosis counteracts the development of opioid tolerance. Mol Pharmacol (2004) 2.36

Internalization of sst2, sst3, and sst5 receptors: effects of somatostatin agonists and antagonists. J Nucl Med (2006) 2.23

A dual role for the SDF-1/CXCR4 chemokine receptor system in adult brain: isoform-selective regulation of SDF-1 expression modulates CXCR4-dependent neuronal plasticity and cerebral leukocyte recruitment after focal ischemia. J Neurosci (2002) 2.08

Effect of the A118G polymorphism on binding affinity, potency and agonist-mediated endocytosis, desensitization, and resensitization of the human mu-opioid receptor. J Neurochem (2004) 2.07

Cxcr7 controls neuronal migration by regulating chemokine responsiveness. Neuron (2011) 1.76

Trifunctional somatostatin-based derivatives designed for targeted radiotherapy using auger electron emitters. J Nucl Med (2005) 1.64

Ecology, inhibitory activity, and morphogenesis of a marine antagonistic bacterium belonging to the Roseobacter clade. Appl Environ Microbiol (2005) 1.56

Discovery of complex mixtures of novel long-chain quorum sensing signals in free-living and host-associated marine alphaproteobacteria. Chembiochem (2005) 1.56

Heterodimerization of somatostatin and opioid receptors cross-modulates phosphorylation, internalization, and desensitization. J Biol Chem (2002) 1.54

Composition of human skin microbiota affects attractiveness to malaria mosquitoes. PLoS One (2011) 1.47

Potent anti-inflammatory and antinociceptive activity of the endothelin receptor antagonist bosentan in monoarthritic mice. Arthritis Res Ther (2011) 1.42

Agonist-selective patterns of µ-opioid receptor phosphorylation revealed by phosphosite-specific antibodies. Br J Pharmacol (2011) 1.40

Heterodimerization of substance P and mu-opioid receptors regulates receptor trafficking and resensitization. J Biol Chem (2003) 1.40

CXCR4 and Gab1 cooperate to control the development of migrating muscle progenitor cells. Genes Dev (2005) 1.40

Volatiles released by a Streptomyces species isolated from the North Sea. Chem Biodivers (2005) 1.38

Autoinducer-2-regulated genes in Streptococcus mutans UA159 and global metabolic effect of the luxS mutation. J Bacteriol (2007) 1.37

Biosynthesis of volatiles by the myxobacterium Myxococcus xanthus. Chembiochem (2004) 1.35

Regional and cellular localization of the CXCl12/SDF-1 chemokine receptor CXCR7 in the developing and adult rat brain. J Comp Neurol (2008) 1.35

Differential attraction of malaria mosquitoes to volatile blends produced by human skin bacteria. PLoS One (2010) 1.34

Differential beta-arrestin trafficking and endosomal sorting of somatostatin receptor subtypes. J Biol Chem (2004) 1.32

Creating knowledge repositories from biomedical reports: the MEDSYNDIKATE text mining system. Pac Symp Biocomput (2002) 1.31

Differential effects of octreotide and pasireotide on somatostatin receptor internalization and trafficking in vitro. J Clin Endocrinol Metab (2008) 1.31

Identification and biosynthesis of tropone derivatives and sulfur volatiles produced by bacteria of the marine Roseobacter clade. Org Biomol Chem (2009) 1.30

Enhanced expression of the CXCl12/SDF-1 chemokine receptor CXCR7 after cerebral ischemia in the rat brain. J Neuroimmunol (2008) 1.27

Patterns of SDF-1alpha and SDF-1gamma mRNAs, migration pathways, and phenotypes of CXCR4-expressing neurons in the developing rat telencephalon. J Comp Neurol (2007) 1.27

Somatostatin signaling in neuronal cilia is critical for object recognition memory. J Neurosci (2010) 1.23

Reassessment of sst2 somatostatin receptor expression in human normal and neoplastic tissues using the novel rabbit monoclonal antibody UMB-1. J Clin Endocrinol Metab (2008) 1.23

Results of an Internet survey of myoelectric prosthetic hand users. Prosthet Orthot Int (2007) 1.20

Gene Regulation Ontology (GRO): design principles and use cases. Stud Health Technol Inform (2008) 1.18

Membrane glycoprotein M6a interacts with the micro-opioid receptor and facilitates receptor endocytosis and recycling. J Biol Chem (2007) 1.18

Somatostatin receptor subtypes in human pheochromocytoma: subcellular expression pattern and functional relevance for octreotide scintigraphy. J Clin Endocrinol Metab (2003) 1.17

Biosynthesis of the off-flavor 2-methylisoborneol by the myxobacterium Nannocystis exedens. Angew Chem Int Ed Engl (2007) 1.16

Immunohistochemical identification of the PTHR1 parathyroid hormone receptor in normal and neoplastic human tissues. Eur J Endocrinol (2010) 1.16

Comparing of IRS and Her2 as immunohistochemical scoring schemes in gastroenteropancreatic neuroendocrine tumors. Int J Clin Exp Pathol (2012) 1.15

Isosemantic rendering of clinical information using formal ontologies and RDF. Stud Health Technol Inform (2013) 1.15

Indium-111-pentetreotide scintigraphy and somatostatin receptor subtype 2 expression: new prognostic factors for malignant well-differentiated endocrine tumors. J Clin Oncol (2008) 1.15

Logic-based remodeling of the Digital Anatomist Foundational Model. AMIA Annu Symp Proc (2003) 1.14

PET of CXCR4 expression by a (68)Ga-labeled highly specific targeted contrast agent. J Nucl Med (2011) 1.13

Seed odor mediates an obligate ant-plant mutualism in Amazonian rainforests. Proc Natl Acad Sci U S A (2008) 1.13

Deciphering µ-opioid receptor phosphorylation and dephosphorylation in HEK293 cells. Br J Pharmacol (2012) 1.13

Neuronal types expressing mu- and delta-opioid receptor mRNA in the rat hippocampal formation. J Comp Neurol (2004) 1.13

Tropodithietic acid production in Phaeobacter gallaeciensis is regulated by N-acyl homoserine lactone-mediated quorum sensing. J Bacteriol (2011) 1.11

The @neurIST ontology of intracranial aneurysms: providing terminological services for an integrated IT infrastructure. AMIA Annu Symp Proc (2007) 1.11

Cross-language MeSH indexing using morpho-semantic normalization. AMIA Annu Symp Proc (2003) 1.11

New structural variants of homoserine lactones in bacteria. Chembiochem (2009) 1.11

Tonic activation of CXC chemokine receptor 4 in immature granule cells supports neurogenesis in the adult dentate gyrus. J Neurosci (2008) 1.11

Pasireotide and octreotide stimulate distinct patterns of sst2A somatostatin receptor phosphorylation. Mol Endocrinol (2010) 1.10

A novel type of geosmin biosynthesis in myxobacteria. J Org Chem (2005) 1.10

Molecular imaging with ⁶⁸Ga-SSTR PET/CT and correlation to immunohistochemistry of somatostatin receptors in neuroendocrine tumours. Eur J Nucl Med Mol Imaging (2011) 1.10

The German specialist lexicon. Proc AMIA Symp (2002) 1.10

Immunocytochemical identification of VPAC1, VPAC2, and PAC1 receptors in normal and neoplastic human tissues with subtype-specific antibodies. Clin Cancer Res (2004) 1.09

Pain control by CXCR2 ligands through Ca2+-regulated release of opioid peptides from polymorphonuclear cells. FASEB J (2006) 1.09

Towards a top-domain ontology for linking biomedical ontologies. Stud Health Technol Inform (2007) 1.09

Streptococcus mutans inhibits Candida albicans hyphal formation by the fatty acid signaling molecule trans-2-decenoic acid (SDSF). Chembiochem (2010) 1.08

Discovery of skin alkaloids in a miniaturized eleutherodactylid frog from Cuba. Biol Lett (2010) 1.08

Description of Labrenzia alexandrii gen. nov., sp. nov., a novel alphaproteobacterium containing bacteriochlorophyll a, and a proposal for reclassification of Stappia aggregata as Labrenzia aggregata comb. nov., of Stappia marina as Labrenzia marina comb. nov. and of Stappia alba as Labrenzia alba comb. nov., and emended descriptions of the genera Pannonibacter, Stappia and Roseibium, and of the species Roseibium denhamense and Roseibium hamelinense. Int J Syst Evol Microbiol (2007) 1.07

Production of bioactive volatiles by different Burkholderia ambifaria strains. J Chem Ecol (2013) 1.07

Phenotypic and genotypic characterization of carcinomas of the papilla of Vater has prognostic and putative therapeutic implications. Am J Clin Pathol (2011) 1.06

Phospholipase D2 modulates agonist-induced mu-opioid receptor desensitization and resensitization. J Neurochem (2004) 1.06

Chemical ecology of fruit bat foraging behavior in relation to the fruit odors of two species of paleotropical bat-dispersed figs (Ficus hispida and Ficus scortechinii). J Chem Ecol (2007) 1.05

Chemical analysis of volatiles emitted by Pinus svlvestris after induction by insect oviposition. J Chem Ecol (2003) 1.04

Differentiation of opioid drug effects by hierarchical multi-site phosphorylation. Mol Pharmacol (2012) 1.04

Identification and characterization of two novel truncated but functional isoforms of the somatostatin receptor subtype 5 differentially present in pituitary tumors. J Clin Endocrinol Metab (2009) 1.03

Biosynthesis and identification of volatiles released by the myxobacterium Stigmatella aurantiaca. Chembiochem (2005) 1.03

ADP-ribosylation factor-dependent phospholipase D2 activation is required for agonist-induced mu-opioid receptor endocytosis. J Biol Chem (2003) 1.02

Cluster analysis as selection and dereplication tool for the identification of new natural compounds from large sample sets. Chem Biodivers (2006) 1.02

Reassessment of CXCR4 chemokine receptor expression in human normal and neoplastic tissues using the novel rabbit monoclonal antibody UMB-2. PLoS One (2008) 1.01

The sex pheromone of the wasp spider Argiope bruennichi. Angew Chem Int Ed Engl (2010) 1.01

Analgesic tolerance to high-efficacy agonists but not to morphine is diminished in phosphorylation-deficient S375A μ-opioid receptor knock-in mice. J Neurosci (2011) 1.00

Sex-specific chemical cues from immatures facilitate the evolution of mate guarding in Heliconius butterflies. Proc Biol Sci (2009) 1.00

Somatostatin analogs modulate AIP in somatotroph adenomas: the role of the ZAC1 pathway. J Clin Endocrinol Metab (2012) 0.98

Pre-adaptations and the evolution of pollination by sexual deception: Cope's rule of specialization revisited. Proc Biol Sci (2012) 0.97

Usability-driven pruning of large ontologies: the case of SNOMED CT. J Am Med Inform Assoc (2012) 0.97

Novel iso-branched ether lipids as specific markers of developmental sporulation in the myxobacterium Myxococcus xanthus. J Biol Chem (2006) 0.97

Selective loss of somatostatin receptor 2 in octreotide-resistant growth hormone-secreting adenomas. J Clin Endocrinol Metab (2008) 0.96

Anatomical characterization of the neuropeptide S system in the mouse brain by in situ hybridization and immunohistochemistry. J Comp Neurol (2011) 0.96

Automatic mapping of clinical documentation to SNOMED CT. Stud Health Technol Inform (2009) 0.96

OrthoJacket: an active FES-hybrid orthosis for the paralysed upper extremity. Biomed Tech (Berl) (2011) 0.96

The DebugIT core ontology: semantic integration of antibiotics resistance patterns. Stud Health Technol Inform (2010) 0.96

Grains, components and mixtures in biomedical ontologies. J Biomed Semantics (2011) 0.96

Rapid dephosphorylation of G protein-coupled receptors by protein phosphatase 1β is required for termination of β-arrestin-dependent signaling. J Biol Chem (2011) 0.95

Identification of cells expressing somatostatin receptor 2 in the gastrointestinal tract of Sstr2 knockout/lacZ knockin mice. J Comp Neurol (2002) 0.95

Natural products from the integument of nonavian reptiles. Nat Prod Rep (2008) 0.94

You are what you talk: quorum sensing induces individual morphologies and cell division modes in Dinoroseobacter shibae. ISME J (2013) 0.93

Analysing traces of autoinducer-2 requires standardization of the Vibrio harveyi bioassay. Anal Bioanal Chem (2006) 0.93

Substantial migration of SVZ cells to the cortex results in the generation of new neurons in the excitotoxically damaged immature rat brain. Mol Cell Neurosci (2008) 0.93

Effects of guideline-based training on the quality of formal ontologies: a randomized controlled trial. PLoS One (2013) 0.92

UMB-3, a novel rabbit monoclonal antibody, for assessing μ-opioid receptor expression in mouse, rat and human formalin-fixed and paraffin-embedded tissues. Regul Pept (2010) 0.92

The UV-B stimulon of the terrestrial cyanobacterium Nostoc commune comprises early shock proteins and late acclimation proteins. Mol Microbiol (2002) 0.92

Potent antifouling compounds produced by marine Streptomyces. Bioresour Technol (2009) 0.92

Novel caprolactones from a marine streptomycete. J Nat Prod (2004) 0.92

An Ontology driven collaborative development for biomedical terminologies: from the French CCAM to the Australian ICHI coding system. Stud Health Technol Inform (2006) 0.92

Towards a multilingual medical lexicon. AMIA Annu Symp Proc (2006) 0.91