Ustekinumab, an anti-IL-12/23 p40 monoclonal antibody, inhibits radiographic progression in patients with active psoriatic arthritis: results of an integrated analysis of radiographic data from the phase 3, multicentre, randomised, double-blind, placebo-controlled PSUMMIT-1 and PSUMMIT-2 trials.

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Published in Ann Rheum Dis on February 19, 2014

Authors

Arthur Kavanaugh1, Christopher Ritchlin, Proton Rahman, Lluis Puig, Alice B Gottlieb, Shu Li, Yuhua Wang, Lenore Noonan, Carrie Brodmerkel, Michael Song, Alan M Mendelsohn, Iain B McInnes, PSUMMIT-1 and 2 Study Groups

Author Affiliations

1: Rheumatology Allergy and Immunology Division, University of California-San Diego, , La Jolla, California, USA.

Associated clinical trials:

A Study of the Safety and Effectiveness of Ustekinumab in Patients With Psoriatic Arthritis | NCT01009086

A Study of the Safety and Efficacy of Ustekinumab in Patients With Psoriatic Arthritis With and Without Prior Exposure to Anti-TNF Agents | NCT01077362

TNF and IL23 Blocking Agents Gene Expression Ratios in the Psoriatic Arthritis Synovium_(TIGERS) Study (TIGERS) | NCT04261010

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