Published in J Clin Invest on March 01, 2003
IL-1 mediates TNF-induced osteoclastogenesis. J Clin Invest (2005) 3.56
The gut microbiota regulates bone mass in mice. J Bone Miner Res (2012) 2.92
Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment. Nat Rev Rheumatol (2012) 2.28
Decreased bacterial diversity characterizes the altered gut microbiota in patients with psoriatic arthritis, resembling dysbiosis in inflammatory bowel disease. Arthritis Rheumatol (2015) 2.26
Myostatin is a direct regulator of osteoclast differentiation and its inhibition reduces inflammatory joint destruction in mice. Nat Med (2015) 2.15
Assessment of radiographic progression in the spines of patients with ankylosing spondylitis treated with adalimumab for up to 2 years. Arthritis Res Ther (2009) 2.05
Inflammatory arthritis increases mouse osteoclast precursors with myeloid suppressor function. J Clin Invest (2012) 1.72
Fibrocyte activation in rheumatoid arthritis. Rheumatology (Oxford) (2009) 1.68
M-CSF mediates TNF-induced inflammatory osteolysis. J Clin Invest (2005) 1.64
Increased lymphangiogenesis in joints of mice with inflammatory arthritis. Arthritis Res Ther (2007) 1.57
Synovial histopathology of psoriatic arthritis, both oligo- and polyarticular, resembles spondyloarthropathy more than it does rheumatoid arthritis. Arthritis Res Ther (2005) 1.52
NF-(kappa)B-inducing kinase controls lymphocyte and osteoclast activities in inflammatory arthritis. J Clin Invest (2005) 1.50
Osteoclasts; culprits in inflammatory osteolysis. Arthritis Res Ther (2005) 1.43
Cells of the synovium in rheumatoid arthritis. Osteoclasts. Arthritis Res Ther (2007) 1.37
TNFalpha therapy in psoriatic arthritis and psoriasis. Ann Rheum Dis (2004) 1.29
Osteoimmunology in rheumatic diseases. Arthritis Res Ther (2009) 1.22
Identification of a human peripheral blood monocyte subset that differentiates into osteoclasts. Arthritis Res Ther (2006) 1.20
Regulation of human osteoclast development by dendritic cell-specific transmembrane protein (DC-STAMP). J Bone Miner Res (2012) 1.19
CD16 (FcRgammaIII) as a potential marker of osteoclast precursors in psoriatic arthritis. Arthritis Res Ther (2010) 1.17
Elucidating bone marrow edema and myelopoiesis in murine arthritis using contrast-enhanced magnetic resonance imaging. Arthritis Rheum (2008) 1.14
RANKL induces heterogeneous DC-STAMP(lo) and DC-STAMP(hi) osteoclast precursors of which the DC-STAMP(lo) precursors are the master fusogens. J Cell Physiol (2010) 1.13
Immunopathology of psoriasis and psoriatic arthritis. Ann Rheum Dis (2005) 1.12
Erosive arthritis. Arthritis Res Ther (2007) 1.11
TNF inhibits production of stromal cell-derived factor 1 by bone stromal cells and increases osteoclast precursor mobilization from bone marrow to peripheral blood. Arthritis Res Ther (2008) 1.11
Natural killer cells trigger osteoclastogenesis and bone destruction in arthritis. Proc Natl Acad Sci U S A (2010) 1.11
Psoriatic arthritis: from pathogenesis to therapy. Arthritis Res Ther (2009) 1.09
Bone destruction by receptor activator of nuclear factor κB ligand-expressing T cells in chronic gouty arthritis. Arthritis Res Ther (2011) 1.08
Interleukin-34 produced by human fibroblast-like synovial cells in rheumatoid arthritis supports osteoclastogenesis. Arthritis Res Ther (2012) 1.05
Mature and activated osteoclasts exist in the synovium of rapidly destructive coxarthrosis. J Bone Miner Metab (2007) 1.04
Periodontal disease: linking the primary inflammation to bone loss. Clin Dev Immunol (2013) 1.03
The role of RANK ligand/osteoprotegerin in rheumatoid arthritis. Ther Adv Musculoskelet Dis (2012) 1.02
The proliferative human monocyte subpopulation contains osteoclast precursors. Arthritis Res Ther (2009) 1.01
Joint remodelling in inflammatory disease. Ann Rheum Dis (2007) 1.01
Modulation of OPG, RANK and RANKL by human chondrocytes and their implication during osteoarthritis. Rheumatology (Oxford) (2009) 1.00
Managing patients with psoriatic disease: the diagnosis and pharmacologic treatment of psoriatic arthritis in patients with psoriasis. Drugs (2014) 1.00
Psoriatic arthritis treatment: biological response modifiers. Ann Rheum Dis (2005) 0.96
Immunological reaction in TNF-α-mediated osteoclast formation and bone resorption in vitro and in vivo. Clin Dev Immunol (2013) 0.96
Circulating mediators of bone remodeling in psoriatic arthritis: implications for disordered osteoclastogenesis and bone erosion. Arthritis Res Ther (2010) 0.95
Adipokines in psoriatic arthritis patients: the correlations with osteoclast precursors and bone erosions. PLoS One (2012) 0.95
Bone mineral density and body composition in postmenopausal women with psoriasis and psoriatic arthritis. Arthritis Res Ther (2011) 0.95
Flowers of Inula japonica Attenuate Inflammatory Responses. Immune Netw (2010) 0.93
Genetics of susceptibility and treatment response in psoriatic arthritis. Nat Rev Rheumatol (2011) 0.93
Psoriatic arthritis: an update. Arthritis (2012) 0.92
p53 expression in rheumatoid and psoriatic arthritis synovial tissue and association with joint damage. Ann Rheum Dis (2005) 0.92
Relationship between inflammation, bone destruction, and osteoproliferation in the HLA-B27/human β2 -microglobulin-transgenic rat model of spondylarthritis. Arthritis Rheum (2012) 0.92
The IL-23/IL-17 axis in psoriatic arthritis. Autoimmun Rev (2014) 0.90
Role of TNF alpha and PLF in bone remodeling in a rat model of repetitive reaching and grasping. J Cell Physiol (2010) 0.90
NFAT2 is an essential mediator of orthopedic particle-induced osteoclastogenesis. J Orthop Res (2008) 0.89
Effects of HIV infection and antiretroviral therapy with ritonavir on induction of osteoclast-like cells in postmenopausal women. Osteoporos Int (2010) 0.89
Mechanisms modulating inflammatory osteolysis: a review with insights into therapeutic targets. Pathol Res Pract (2008) 0.89
Magnetic resonance imaging in psoriatic arthritis: a review of the literature. Arthritis Res Ther (2006) 0.89
Mechanisms of joint damage in gout: evidence from cellular and imaging studies. Nat Rev Rheumatol (2012) 0.89
The role of the lymphatic system in inflammatory-erosive arthritis. Semin Cell Dev Biol (2015) 0.88
Efficacy of infliximab on MRI-determined bone oedema in psoriatic arthritis. Ann Rheum Dis (2006) 0.88
Etanercept prevents airway hyperresponsiveness by protecting neuronal M2 muscarinic receptors in antigen-challenged guinea pigs. Br J Pharmacol (2009) 0.88
Role of IL-17 in the pathogenesis of psoriatic arthritis and axial spondyloarthritis. Clin Rheumatol (2015) 0.88
Decreased levels of metalloproteinase-9 and angiogenic factors in skin lesions of patients with psoriatic arthritis after therapy with anti-TNF-alpha. J Autoimmune Dis (2006) 0.86
Bone effects of biologic drugs in rheumatoid arthritis. Clin Dev Immunol (2013) 0.86
Autocrine signaling is a key regulatory element during osteoclastogenesis. Biol Open (2014) 0.86
Ethanol extract of Angelica gigas inhibits croton oil-induced inflammation by suppressing the cyclooxygenase - prostaglandin pathway. J Vet Sci (2010) 0.86
The diagnosis and treatment of early psoriatic arthritis. Nat Rev Rheumatol (2009) 0.85
The adaptive nature of the bone-periodontal ligament-cementum complex in a ligature-induced periodontitis rat model. Biomed Res Int (2013) 0.85
Role of TNF-α in virus-induced airway hyperresponsiveness and neuronal M₂ muscarinic receptor dysfunction. Br J Pharmacol (2011) 0.85
Mediation of nonerosive arthritis in a mouse model of lupus by interferon-alpha-stimulated monocyte differentiation that is nonpermissive of osteoclastogenesis. Arthritis Rheum (2010) 0.85
Synergistic anti-inflammatory effects of Laminaria japonica fucoidan and Cistanche tubulosa extract. Lab Anim Res (2012) 0.85
Synovial effusion and synovial fluid biomarkers in psoriatic arthritis to assess intraarticular tumor necrosis factor-α blockade in the knee joint. Arthritis Res Ther (2010) 0.85
Bone mineral density and bone turnover in patients with psoriatic arthritis. Clin Rheumatol (2007) 0.84
High-fat diet causes bone loss in young mice by promoting osteoclastogenesis through alteration of the bone marrow environment. Calcif Tissue Int (2015) 0.84
Clinical, radiological, and functional assessment in psoriatic arthritis: is it different from other inflammatory joint diseases? Ann Rheum Dis (2006) 0.84
Synovial fibroblasts infected with Salmonella enterica serovar Typhimurium mediate osteoclast differentiation and activation. Infect Immun (2004) 0.83
RANKL is a mediator of bone resorption in idiopathic hypercalciuria. Clin J Am Soc Nephrol (2008) 0.83
The Th17 axis in psoriatic disease: pathogenetic and therapeutic implications. Auto Immun Highlights (2014) 0.83
A new insight to bone turnover: role of ω-3 polyunsaturated fatty acids. ScientificWorldJournal (2013) 0.83
Bone density loss in Crohn's disease: role of TNF and potential for prevention by bupropion. Gut (2004) 0.82
TNF-α-induced NF-κB activation upregulates microRNA-150-3p and inhibits osteogenesis of mesenchymal stem cells by targeting β-catenin. Open Biol (2016) 0.82
Association of systemic and intra-articular osteoclastogenic potential, pro-inflammatory mediators and disease activity with the form of inflammatory arthritis. Int Orthop (2013) 0.82
Alendronate reduces osteoclast precursors in osteoporosis. Osteoporos Int (2009) 0.82
Risk factors for radiographic progression in psoriatic arthritis: subanalysis of the randomized controlled trial ADEPT. Arthritis Res Ther (2010) 0.82
Early treatment with addition of low dose prednisolone to methotrexate improves therapeutic outcome in severe psoriatic arthritis. Indian J Dermatol (2013) 0.81
The emerging field of osteoimmunology. Immunol Res (2009) 0.81
Modulation of osteoclastogenesis induced by nucleoside reverse transcriptase inhibitors. AIDS Res Hum Retroviruses (2006) 0.80
Infliximab (Remicade) in the treatment of psoriatic arthritis. Ther Clin Risk Manag (2006) 0.80
Prevention of bone mineral density loss in patients with rheumatoid arthritis treated with anti-TNFalpha therapy. Biologics (2008) 0.80
IL-23/IL-17 axis in spondyloarthritis-bench to bedside. Clin Rheumatol (2016) 0.80
Psoriasis: new comorbidities. An Bras Dermatol (2016) 0.80
Titanium particles stimulate COX-2 expression in synovial fibroblasts through an oxidative stress-induced, calpain-dependent, NF-kappaB pathway. Am J Physiol Cell Physiol (2009) 0.79
The role of bone marrow edema and lymphangiogenesis in inflammatory-erosive arthritis. Adv Exp Med Biol (2010) 0.79
Association of Acroosteolysis With Enhanced Osteoclastogenesis and Higher Blood Levels of Vascular Endothelial Growth Factor in Systemic Sclerosis. Arthritis Rheumatol (2016) 0.79
[Bone metabolism: molecular mechanisms]. Z Rheumatol (2007) 0.79
Myeloid-derived suppressor cells contribute to bone erosion in collagen-induced arthritis by differentiating to osteoclasts. J Autoimmun (2015) 0.78
Tumor cell p38 MAPK: A trigger of cancer bone osteolysis. Cancer Cell Microenviron (2015) 0.78
Increased generation of TRAP expressing multinucleated giant cells in patients with granulomatosis with polyangiitis. PLoS One (2012) 0.78
Interleukin-4 inhibits RANKL-induced NFATc1 expression via STAT6: a novel mechanism mediating its blockade of osteoclastogenesis. J Cell Biochem (2011) 0.78
Emerging biomarkers in psoriatic arthritis. IUBMB Life (2015) 0.78
Regulation of peripheral classical and non-classical monocytes on infliximab treatment in patients with rheumatoid arthritis and ankylosing spondylitis. RMD Open (2016) 0.77
[New aspects on the pathogenesis of psoriatic arthritis]. Z Rheumatol (2013) 0.77
Inhibition of TNF-α Reverses the Pathological Resorption Pit Profile of Osteoclasts from Patients with Acute Charcot Osteoarthropathy. J Diabetes Res (2015) 0.77
Lipopolysaccharide-induced epithelial monoamine oxidase mediates alveolar bone loss in a rat chronic wound model. Am J Pathol (2009) 0.77
Altered bone remodeling in psoriatic arthritis. Curr Rheumatol Rep (2008) 0.77
The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum (1988) 111.05
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell (1998) 17.76
Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell (1997) 15.96
Bone resorption by osteoclasts. Science (2000) 11.68
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand. Nature (1999) 8.23
Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr Rev (1999) 7.69
Etanercept in the treatment of psoriatic arthritis and psoriasis: a randomised trial. Lancet (2000) 6.49
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-gamma. Nature (2000) 6.49
Psoriatic arthritis. Semin Arthritis Rheum (1973) 6.08
TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand. J Clin Invest (2000) 5.78
Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction. J Exp Med (2000) 5.02
TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis. Am J Pathol (2001) 3.53
Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor. Arthritis Rheum (2000) 3.51
Tumor necrosis factor-alpha induces differentiation of and bone resorption by osteoclasts. J Biol Chem (2000) 2.80
Identification of cell types responsible for bone resorption in rheumatoid arthritis and juvenile rheumatoid arthritis. Am J Pathol (1998) 2.68
RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis. Biochem Biophys Res Commun (1998) 2.62
Efficacy of etanercept in the treatment of the entheseal pathology in resistant spondylarthropathy: a clinical and magnetic resonance imaging study. Arthritis Rheum (2001) 2.49
Paravertebral ossification in psoriatic arthritis. Ann Rheum Dis (1965) 2.11
Receptor activator of NF-kappa B and osteoprotegerin expression by human microvascular endothelial cells, regulation by inflammatory cytokines, and role in human osteoclastogenesis. J Biol Chem (2001) 2.02
Gene expression of osteoprotegerin ligand, osteoprotegerin, and receptor activator of NF-kappaB in giant cell tumor of bone: possible involvement in tumor cell-induced osteoclast-like cell formation. Am J Pathol (2000) 1.99
Expression of osteoclast differentiation factor in rheumatoid arthritis. Arthritis Rheum (2000) 1.92
A re-evaluation of the osteoarticular manifestations of psoriasis. Br J Rheumatol (1991) 1.88
Activated human T cells directly induce osteoclastogenesis from human monocytes: possible role of T cells in bone destruction in rheumatoid arthritis patients. Arthritis Rheum (2001) 1.85
Chondroclasts and osteoclasts at subchondral sites of erosion in the rheumatoid joint. Arthritis Rheum (1984) 1.85
A combination of osteoclast differentiation factor and macrophage-colony stimulating factor is sufficient for both human and mouse osteoclast formation in vitro. Endocrinology (1998) 1.75
Patterns of cytokine production in psoriatic synovium. J Rheumatol (1998) 1.72
Tumor necrosis factor alpha-mediated joint destruction is inhibited by targeting osteoclasts with osteoprotegerin. Arthritis Rheum (2002) 1.72
Macrophage-derived cytokine and nuclear factor kappaB p65 expression in synovial membrane and skin of patients with psoriatic arthritis. Arthritis Rheum (2000) 1.65
Distinct vascular patterns of early synovitis in psoriatic, reactive, and rheumatoid arthritis. Arthritis Rheum (1999) 1.65
Mechanisms of bone loss in inflammatory arthritis: diagnosis and therapeutic implications. Arthritis Res (1999) 1.59
Clinical review 114: hot topic. The role of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in the pathogenesis and treatment of metabolic bone diseases. J Clin Endocrinol Metab (2000) 1.45
The expression of osteoprotegerin and RANK ligand and the support of osteoclast formation by stromal-osteoblast lineage cells is developmentally regulated. Endocrinology (2000) 1.43
Human osteoclast formation and bone resorption by monocytes and synovial macrophages in rheumatoid arthritis. Ann Rheum Dis (1996) 1.35
A new mechanism of bone destruction in rheumatoid arthritis: synovial fibroblasts induce osteoclastogenesis. Biochem Biophys Res Commun (1997) 1.33
Human osteoclasts derive from CD14-positive monocytes. Br J Haematol (1999) 1.30
THE PATTERN OF BONE EROSION IN THE HAND AND WRIST IN RHEUMATOID ARTHRITIS. Radiology (1965) 1.27
Osteoclast markers accumulate on cells developing from human peripheral blood mononuclear precursors. J Cell Biochem (1999) 1.24
Induction of osteoclasts from CD14-positive human peripheral blood mononuclear cells by receptor activator of nuclear factor kappaB ligand (RANKL). Clin Sci (Lond) (2000) 1.23
Psoriatic arthritis. Rheum Dis Clin North Am (1998) 1.15
Characterization of osteoclast precursors in human blood. Br J Haematol (2000) 1.14
The role of osteoprotegerin and receptor activator of nuclear factor kappaB ligand in the pathogenesis and treatment of rheumatoid arthritis. Arthritis Rheum (2001) 1.05
T cell derived cytokines in psoriatic arthritis synovial fluids. Ann Rheum Dis (1998) 1.02
Expression of functional RANK on mature rat and human osteoclasts. FEBS Lett (1999) 0.93
Abnormalities in osteoclast precursors and marrow accessory cells in Paget's disease. Endocrinology (1993) 0.90
On the nature and significance of bony proliferation in "rheumatoid variant" disorders. AJR Am J Roentgenol (1977) 0.88
Cytokine-activated endothelium recruits osteoclast precursors. Endocrinology (2001) 0.87
Expression of interleukin 10 mRNA and protein by synovial fibroblastoid cells. J Rheumatol (2001) 0.87
Osteoclastogenesis in iliac bone marrow of patients with rheumatoid arthritis. J Rheumatol (1997) 0.83
Osteoclast precursors circulate in the peripheral blood of patients with aggressive multiple myeloma. Leukemia (1995) 0.83
A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (2002) 42.78
American Society of Clinical Oncology/College Of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer. J Clin Oncol (2010) 14.41
Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update. J Clin Oncol (2013) 12.57
PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell (2004) 10.89
Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases. Am J Pathol (2003) 8.61
Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways. Nat Med (2011) 6.21
Chronic dialysis and death among survivors of acute kidney injury requiring dialysis. JAMA (2009) 6.06
Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance. Cell Metab (2010) 5.82
Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity. Nature (2011) 4.78
Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals. J Biol Chem (2007) 4.58
Statins and sepsis in patients with cardiovascular disease: a population-based cohort analysis. Lancet (2006) 4.42
American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer (unabridged version). Arch Pathol Lab Med (2010) 4.38
Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency. J Biol Chem (2005) 4.30
Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis. Cell (2010) 4.01
Reader's guide to critical appraisal of cohort studies: 2. Assessing potential for confounding. BMJ (2005) 3.94
When laboratories report estimated glomerular filtration rates in addition to serum creatinines, nephrology consults increase. Kidney Int (2009) 3.70
Uric acid stimulates monocyte chemoattractant protein-1 production in vascular smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2. Hypertension (2003) 3.39
Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair. J Clin Invest (2002) 3.29
Mirid bug outbreaks in multiple crops correlated with wide-scale adoption of Bt cotton in China. Science (2010) 3.09
An integrated physical and genetic map of the rice genome. Plant Cell (2002) 3.07
Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway. J Biol Chem (2005) 3.06
Genetic heterogeneity in HER2 testing in breast cancer: panel summary and guidelines. Arch Pathol Lab Med (2009) 2.97
Syncope and its consequences in patients with dementia receiving cholinesterase inhibitors: a population-based cohort study. Arch Intern Med (2009) 2.96
Production of p53 gene knockout rats by homologous recombination in embryonic stem cells. Nature (2010) 2.92
Prevalence, predictors, and outcomes of primary nonadherence after acute myocardial infarction. Circulation (2008) 2.76
American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer. Arch Pathol Lab Med (2010) 2.72
Stromal cell-derived factor 1/CXCR4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model. Arthritis Rheum (2009) 2.64
Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situ. Mol Cell (2010) 2.64
The Expression Patterns of ER, PR, HER2, CK5/6, EGFR, Ki-67 and AR by Immunohistochemical Analysis in Breast Cancer Cell Lines. Breast Cancer (Auckl) (2010) 2.57
Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update. Arch Pathol Lab Med (2013) 2.54
STAT3 is constitutively phosphorylated on serine 727 residues, binds DNA, and activates transcription in CLL cells. Blood (2010) 2.48
Nephrologist follow-up improves all-cause mortality of severe acute kidney injury survivors. Kidney Int (2013) 2.42
Antiretroviral therapy to prevent HIV transmission in serodiscordant couples in China (2003-11): a national observational cohort study. Lancet (2012) 2.41
Lamp-2a facilitates MHC class II presentation of cytoplasmic antigens. Immunity (2005) 2.40
A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo. J Neurosci (2005) 2.28
Overexpression of noggin inhibits BMP-mediated growth of osteolytic prostate cancer lesions. Bone (2005) 2.26
Recommendations for improved standardization of immunohistochemistry. Appl Immunohistochem Mol Morphol (2007) 2.24
NF-kappaB p50 and p52 regulate receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1. J Biol Chem (2007) 2.22
Extensive turnover of dendritic spines and vascular remodeling in cortical tissues recovering from stroke. J Neurosci (2007) 2.19
Runx2-mediated regulation of the zinc finger Osterix/Sp7 gene. Gene (2006) 2.16
A new rabbit monoclonal antibody (4B5) for the immunohistochemical (IHC) determination of the HER2 status in breast cancer: comparison with CB11, fluorescence in situ hybridization (FISH), and interlaboratory reproducibility. Appl Immunohistochem Mol Morphol (2007) 2.15
CIITA-regulated plexin-A1 affects T-cell-dendritic cell interactions. Nat Immunol (2003) 2.13
Remodeling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy. Nat Med (2005) 2.10
14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelial-mesenchymal transition. Cancer Cell (2009) 2.09
Promising clinical outcome of stereotactic body radiation therapy for patients with inoperable Stage I/II non-small-cell lung cancer. Int J Radiat Oncol Biol Phys (2006) 2.04
Periosteal progenitor cell fate in segmental cortical bone graft transplantations: implications for functional tissue engineering. J Bone Miner Res (2005) 2.04
Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo. J Biol Chem (2005) 2.04
Knockdown of NOB1 expression by RNAi inhibits cellular proliferation and migration in human gliomas. Gene (2013) 2.03
Vascular endothelial growth factor C attenuates joint damage in chronic inflammatory arthritis by accelerating local lymphatic drainage in mice. Arthritis Rheum (2011) 1.98
Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts. J Biol Chem (2005) 1.96
Cholinesterase inhibitors and hospitalization for bradycardia: a population-based study. PLoS Med (2009) 1.94
Systemic tumor necrosis factor alpha mediates an increase in peripheral CD11bhigh osteoclast precursors in tumor necrosis factor alpha-transgenic mice. Arthritis Rheum (2004) 1.94
Expanded CD23(+)/CD21(hi) B cells in inflamed lymph nodes are associated with the onset of inflammatory-erosive arthritis in TNF-transgenic mice and are targets of anti-CD20 therapy. J Immunol (2010) 1.94
A genome-wide association study identifies two new risk loci for Graves' disease. Nat Genet (2011) 1.92
Sex-and age-based differences in the delivery and outcomes of critical care. CMAJ (2007) 1.91
Diagnosis of severe acute respiratory syndrome (SARS) by detection of SARS coronavirus nucleocapsid antibodies in an antigen-capturing enzyme-linked immunosorbent assay. J Clin Microbiol (2003) 1.85
COX-1 and COX-2 expression in osteoid osteomas. J Orthop Res (2002) 1.84
RANK signaling is not required for TNFalpha-mediated increase in CD11(hi) osteoclast precursors but is essential for mature osteoclast formation in TNFalpha-mediated inflammatory arthritis. J Bone Miner Res (2004) 1.83
Two-photon imaging of stroke onset in vivo reveals that NMDA-receptor independent ischemic depolarization is the major cause of rapid reversible damage to dendrites and spines. J Neurosci (2008) 1.79
Mycobacterium tuberculosis prcBA genes encode a gated proteasome with broad oligopeptide specificity. Mol Microbiol (2006) 1.79
Infection-associated clinical outcomes in hospitalized medical evacuees after traumatic injury: trauma infectious disease outcome study. J Trauma (2011) 1.77
Readers guide to critical appraisal of cohort studies: 3. Analytical strategies to reduce confounding. BMJ (2005) 1.76
Tumor necrosis factor-alpha increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression. J Biol Chem (2006) 1.73
Double knockout pigs deficient in N-glycolylneuraminic acid and galactose α-1,3-galactose reduce the humoral barrier to xenotransplantation. Xenotransplantation (2013) 1.72
PGC-1alpha plays a functional role in exercise-induced mitochondrial biogenesis and angiogenesis but not fiber-type transformation in mouse skeletal muscle. Am J Physiol Cell Physiol (2009) 1.72
Contemporary clinical research of traditional Chinese medicines for chronic hepatitis B in China: an analytical review. Hepatology (2010) 1.71
Voluntary running induces fiber type-specific angiogenesis in mouse skeletal muscle. Am J Physiol Cell Physiol (2004) 1.71
Novel prognostic immunohistochemical biomarker panel for estrogen receptor-positive breast cancer. J Clin Oncol (2006) 1.70
Consensus recommendations on estrogen receptor testing in breast cancer by immunohistochemistry. Appl Immunohistochem Mol Morphol (2008) 1.69
The expression of fascin, an actin-bundling motility protein, correlates with hormone receptor-negative breast cancer and a more aggressive clinical course. Clin Cancer Res (2005) 1.68
The 76-gene signature defines high-risk patients that benefit from adjuvant tamoxifen therapy. Breast Cancer Res Treat (2008) 1.68
Longitudinal assessment of synovial, lymph node, and bone volumes in inflammatory arthritis in mice by in vivo magnetic resonance imaging and microfocal computed tomography. Arthritis Rheum (2007) 1.68
Conditional activation of β-catenin signaling in mice leads to severe defects in intervertebral disc tissue. Arthritis Rheum (2012) 1.67
Phosphorylation on tyrosine-15 of p34(Cdc2) by ErbB2 inhibits p34(Cdc2) activation and is involved in resistance to taxol-induced apoptosis. Mol Cell (2002) 1.67
Atypical antipsychotics and parkinsonism. Arch Intern Med (2005) 1.66
ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development. J Bone Miner Res (2003) 1.66
Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP. Science (2007) 1.64
Statins and intracerebral hemorrhage: a retrospective cohort study. Arch Neurol (2011) 1.63
Detection of survivin-expressing circulating cancer cells (CCCs) in peripheral blood of patients with gastric and colorectal cancer reveals high risks of relapse. Ann Surg Oncol (2008) 1.62
Safety and cross-reactive immunogenicity of candidate AS03-adjuvanted prepandemic H5N1 influenza vaccines: a randomized controlled phase 1/2 trial in adults. J Infect Dis (2010) 1.60
γδT Cell-derived interleukin-17A via an interleukin-1β-dependent mechanism mediates cardiac injury and fibrosis in hypertension. Hypertension (2014) 1.59
Osteoclast precursors, RANKL/RANK, and immunology. Immunol Rev (2005) 1.57
Increased lymphangiogenesis in joints of mice with inflammatory arthritis. Arthritis Res Ther (2007) 1.57
A perspective: engineering periosteum for structural bone graft healing. Clin Orthop Relat Res (2008) 1.57
Risk of mycobacterial infections associated with rheumatoid arthritis in Ontario, Canada. Chest (2014) 1.57
Invasive mold infections following combat-related injuries. Clin Infect Dis (2012) 1.55
Construction of genetic linkage maps and comparative genome analysis of catfish using gene-associated markers. Genetics (2009) 1.55
Inhibition of lymphangiogenesis and lymphatic drainage via vascular endothelial growth factor receptor 3 blockade increases the severity of inflammation in a mouse model of chronic inflammatory arthritis. Arthritis Rheum (2009) 1.54
Embryonic stem cell self-renewal pathways converge on the transcription factor Tfcp2l1. EMBO J (2013) 1.50
Safety and long-term humoral immune response in adults after vaccination with an H1N1 2009 pandemic influenza vaccine with or without AS03 adjuvant. J Infect Dis (2012) 1.50
Patients With Ankylosing Spondylitis Have Increased Cardiovascular and Cerebrovascular Mortality: A Population-Based Study. Ann Intern Med (2015) 1.49
Biological effects of rAAV-caAlk2 coating on structural allograft healing. Mol Ther (2005) 1.49
Mutations of the GABA-A receptor alpha1 subunit M1 domain reveal unexpected complexity for modulation by neuroactive steroids. Mol Pharmacol (2008) 1.46
Down-regulation of WAVE3, a metastasis promoter gene, inhibits invasion and metastasis of breast cancer cells. Am J Pathol (2007) 1.46
Wnt induction of chondrocyte hypertrophy through the Runx2 transcription factor. J Cell Physiol (2006) 1.46
Results of a randomized controlled trial on statin use in dialysis patients had no influence on statin prescription. Kidney Int (2009) 1.45
The TNF-alpha transgenic mouse model of inflammatory arthritis. Springer Semin Immunopathol (2003) 1.44
An AFLP-based genetic linkage map of channel catfish (Ictalurus punctatus) constructed by using an interspecific hybrid resource family. Genetics (2003) 1.44