PubRank

Michelle A Dunstone

Author PubWeight™ 31.13‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A common fold mediates vertebrate defense and bacterial attack. Science 2007 3.43
2 Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations. Nat Immunol 2005 2.44
3 The structural basis for membrane binding and pore formation by lymphocyte perforin. Nature 2010 2.23
4 The MACPF/CDC family of pore-forming toxins. Cell Microbiol 2008 2.15
5 The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65. PLoS Pathog 2010 2.03
6 Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor. Immunity 2009 1.40
7 Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3. Proc Natl Acad Sci U S A 2004 1.38
8 Perforin: structure, function, and role in human immunopathology. Immunol Rev 2010 1.30
9 Epitope-specific TCRbeta repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides. Proc Natl Acad Sci U S A 2008 1.24
10 Crystal structure of HLA-G: a nonclassical MHC class I molecule expressed at the fetal-maternal interface. Proc Natl Acad Sci U S A 2005 1.20
11 Temperature sensitivity of human perforin mutants unmasks subtotal loss of cytotoxicity, delayed FHL, and a predisposition to cancer. Proc Natl Acad Sci U S A 2009 1.14
12 Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition. Proc Natl Acad Sci U S A 2010 1.13
13 Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue. J Biol Chem 2004 1.10
14 Specificity on a knife-edge: the alphabeta T cell receptor. Curr Opin Struct Biol 2006 1.03
15 T cell determinants incorporating beta-amino acid residues are protease resistant and remain immunogenic in vivo. J Immunol 2005 0.98
16 Perforin evolved from a gene duplication of MPEG1, followed by a complex pattern of gene gain and loss within Euteleostomi. BMC Evol Biol 2012 0.91
17 The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance. J Immunol 2004 0.90
18 Predicting giant transmembrane β-barrel architecture. Bioinformatics 2012 0.90
19 Structural and biological basis of CTL escape in coronavirus-infected mice. J Immunol 2008 0.89
20 Enzymatic properties of an ecto-nucleoside triphosphate diphosphohydrolase from Legionella pneumophila: substrate specificity and requirement for virulence. J Biol Chem 2008 0.85
21 Screening of 71 P. multocida proteins for protective efficacy in a fowl cholera infection model and characterization of the protective antigen PlpE. PLoS One 2012 0.84
22 Prevention of cytotoxic T cell escape using a heteroclitic subdominant viral T cell determinant. PLoS Pathog 2008 0.82
23 The perforin pore facilitates the delivery of cationic cargos. J Biol Chem 2014 0.79
24 Structural biology: Torqueing about pores. Nat Chem Biol 2013 0.75