Published in EMBO J on March 01, 1988
Role in host cell invasion of Trypanosoma cruzi-induced cytosolic-free Ca2+ transients. J Exp Med (1994) 1.84
Galanin activates nucleotide-dependent K+ channels in insulin-secreting cells via a pertussis toxin-sensitive G-protein. EMBO J (1989) 1.35
Cyclic AMP-independent, dual regulation of voltage-dependent Ca2+ currents by LHRH and somatostatin in a pituitary cell line. EMBO J (1988) 0.98
Thyrotropin-releasing hormone induces opposite effects on Ca2+ channel currents in pituitary cells by two pathways. Proc Natl Acad Sci U S A (1991) 0.96
Gi2 and protein kinase C are required for thyrotropin-releasing hormone-induced stimulation of voltage-dependent Ca2+ channels in rat pituitary GH3 cells. Proc Natl Acad Sci U S A (1993) 0.92
Beta gamma subunits of GTP-binding proteins inhibit muscarinic receptor stimulation of phospholipase C. Proc Natl Acad Sci U S A (1988) 0.88
Angiotensin II inhibits K(+)-induced Ca2+ signal generation in rat adrenal glomerulosa cells. Biochem J (1991) 0.87
T-type calcium channels in adrenal glomerulosa cells: GTP-dependent modulation by angiotensin II. Proc Natl Acad Sci U S A (1993) 0.84
Stimulation of single L-type calcium channels in rat pituitary GH3 cells by thyrotropin-releasing hormone. EMBO J (1995) 0.83
A pertussis toxin-sensitive mechanism of endothelin action in porcine coronary artery smooth muscle. Br J Pharmacol (1992) 0.83
Occurrence of the alpha subunits of G proteins in cerebral cortex synaptic membrane and postsynaptic density fractions: modulation of ADP-ribosylation by Ca2+/calmodulin. Proc Natl Acad Sci U S A (1992) 0.81
The peptide CGRP increases a high-threshold Ca2+ current in rat nodose neurones via a pertussis toxin-sensitive pathway. J Physiol (1992) 0.81
Changes in the cytosolic Ca2+ concentration and Ca(2+)-sensitivity of the contractile apparatus during angiotensin II-induced desensitization in the rabbit femoral artery. Br J Pharmacol (2000) 0.79
Activation of AT1 angiotensin receptors induces DNA synthesis in a rat intestinal epithelial (RIE-1) cell line. Biochem J (1994) 0.76
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch (1981) 134.60
Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists. Nature (1984) 10.27
Three types of neuronal calcium channel with different calcium agonist sensitivity. Nature (1985) 9.68
Immunogenic structure of the influenza virus hemagglutinin. Cell (1982) 8.93
Calcium channel modulation by neurotransmitters, enzymes and drugs. Nature (1983) 6.76
The enzymatic preparation of [alpha-32P]ATP, [alpha-32P]GTP, [32P]cAMP, and [32P]cGMP, and their use in the assay of adenylate and guanylate cyclases and cyclic nucleotide phosphodiesterases. Adv Cyclic Nucleotide Res (1979) 5.93
A low voltage-activated, fully inactivating Ca channel in vertebrate sensory neurones. Nature (1984) 5.54
Mechanism of cholera toxin action: covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system. Proc Natl Acad Sci U S A (1978) 5.49
Two kinds of calcium channels in canine atrial cells. Differences in kinetics, selectivity, and pharmacology. J Gen Physiol (1985) 5.16
The GTP-binding protein, Go, regulates neuronal calcium channels. Nature (1987) 3.24
Adenosine 3',5'-monophosphate as the intracellular mediator of the action of adrenocorticotropic hormone on the adrenal cortex. J Biol Chem (1967) 3.03
GTP-binding proteins mediate transmitter inhibition of voltage-dependent calcium channels. Nature (1986) 3.01
On the mechanism of beta-adrenergic regulation of the Ca channel in the guinea-pig heart. Pflugers Arch (1985) 2.93
Antisera of designed specificity for subunits of guanine nucleotide-binding regulatory proteins. Proc Natl Acad Sci U S A (1986) 2.87
Forskolin: its biological and chemical properties. Adv Cyclic Nucleotide Protein Phosphorylation Res (1986) 2.68
Direct activation of mammalian atrial muscarinic potassium channels by GTP regulatory protein Gk. Science (1987) 2.50
Voltage-activated calcium channels that must be phosphorylated to respond to membrane depolarization. Proc Natl Acad Sci U S A (1987) 2.48
Modulation of Ca current during the phosphorylation cycle in the guinea pig heart. Pflugers Arch (1986) 2.26
On the mechanism of muscarinic inhibition of the cardiac Ca current. Pflugers Arch (1986) 1.95
The alpha subunit of the GTP binding protein Gk opens atrial potassium channels. Science (1987) 1.79
Comparison of prolactin levels in human semen and seminal plasma. J Endocrinol (1979) 1.74
A guanine nucleotide-binding protein mediates the inhibition of voltage-dependent calcium current by somatostatin in a pituitary cell line. Proc Natl Acad Sci U S A (1986) 1.62
The temporal integration of the aldosterone secretory response to angiotensin occurs via two intracellular pathways. J Biol Chem (1984) 1.55
Regulation of calcium currents by a GTP analogue: potentiation of (-)-baclofen-mediated inhibition. Neurosci Lett (1986) 1.34
Islet-activating protein, pertussis toxin: a specific uncoupler of receptor-mediated inhibition of adenylate cyclase. Adv Cyclic Nucleotide Protein Phosphorylation Res (1984) 1.33
The human genome encodes at least three non-allellic G proteins with alpha i-type subunits. FEBS Lett (1987) 1.20
Angiotensin II receptors in bovine adrenal cortex. Modification of angiotensin II binding by guanyl nucleotides. J Biol Chem (1974) 1.14
The role of calcium in the stimulation of aldosterone production by adrenocorticotropin, angiotensin II, and potassium in isolated glomerulosa cells. Endocrinology (1979) 1.13
Participation of voltage-dependent calcium channels in the regulation of adrenal glomerulosa function by angiotensin II and potassium. Endocrinology (1986) 1.12
Adrenocorticotropin action in isolated adrenal cells. The intermediate role of cyclic AMP in stimulation of corticosterone synthesis. J Biol Chem (1979) 1.09
Characteristics of angiotensin II-, K+- and ACTH-induced calcium influx in adrenal glomerulosa cells. Evidence that angiotensin II, K+, and ACTH may open a common calcium channel. J Biol Chem (1985) 1.07
Dihydropyridine calcium agonist and antagonist effects on aldosterone secretion. Am J Physiol (1984) 1.06
Calcium: its role in the mechanism of action of angiotensin II and potassium in aldosterone production. Endocrinology (1981) 1.05
Dependence of aldosterone stimulation in adrenal glomerulosa cells on calcium uptake: effects of lanthanum nd verapamil. Endocrinology (1980) 1.04
Transient Ca2+-channel current characterized by a low-threshold voltage in zona glomerulosa cells of rat adrenal cortex. Pflugers Arch (1987) 0.99
Pertussis toxin blocks angiotensin II-induced calcium influx but not inositol trisphosphate production in adrenal glomerulosa cell. FEBS Lett (1986) 0.97
Effects of ANG II and K+ on Ca efflux and aldosterone production in adrenal glomerulosa cells. Am J Physiol (1985) 0.92
NADP efficiently inhibits endogenous but not pertussis toxin-catalyzed covalent modification of membrane proteins incubated with NAD. FEBS Lett (1987) 0.92
Cyclic nucleotides in hormonal regulation of adrenocortical function. Adv Cyclic Nucleotide Res (1980) 0.90
Selective enhancement of angiotensin II- and potassium-stimulated aldosterone secretion by the calcium channel agonist BAY K 8644. Endocrinology (1986) 0.89
Inhibition of adenylate cyclase in rat adrenal glomerulosa cells by angiotensin II. Endocrinology (1984) 0.88
Identification and characterization of the 35-kDa beta subunit of guanine-nucleotide-binding proteins by an antiserum raised against transducin. Eur J Biochem (1986) 0.87
Automaticity of ventricular fibers induced by low concentrations of barium. Am J Physiol (1984) 0.86
The role of guanyl nucleotide binding proteins in the formation of inositol phosphates in adrenal glomerulosa cells. Biochem Biophys Res Commun (1986) 0.84
[Electrophysiological studies on barium-induced pacemaker activity in isolated mammalian myocardium]. Pflugers Arch Gesamte Physiol Menschen Tiere (1965) 0.84
Isolation of ACTH-resistant Y1 adrenal tumor cells. Methods Enzymol (1985) 0.82
Purification of Ns and Ni, the coupling proteins of hormone-sensitive adenylyl cyclases without intervention of activating regulatory ligands. Methods Enzymol (1985) 0.81
Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. Nature (1999) 6.85
Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells. Physiol Rev (1994) 5.51
OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity. Nat Cell Biol (2000) 3.88
Acetylcholine activation of single muscarinic K+ channels in isolated pacemaker cells of the mammalian heart. Nature (1983) 3.34
The GTP-binding protein, Go, regulates neuronal calcium channels. Nature (1987) 3.24
Elementary currents through Ca2+ channels in guinea pig myocytes. Pflugers Arch (1983) 3.10
On the mechanism of beta-adrenergic regulation of the Ca channel in the guinea-pig heart. Pflugers Arch (1985) 2.93
The dynamic chloride component of membrane current in Purkinje fibers. Pflugers Arch Gesamte Physiol Menschen Tiere (1967) 2.90
Inward membrane currents in mammalian myocardium. Pflugers Arch (1972) 2.84
From worm to man: three subfamilies of TRP channels. Trends Neurosci (2000) 2.81
The ionic nature of slow inward current and its relation to contraction. Pflugers Arch (1972) 2.70
The effect of the duration of the action potential on contraction in the mammalian heart muscle. Pflugers Arch Gesamte Physiol Menschen Tiere (1968) 2.68
Molecular cloning of the receptor for human antidiuretic hormone. Nature (1992) 2.44
Purified dihydropyridine-binding site from skeletal muscle t-tubules is a functional calcium channel. Nature (1986) 2.41
Injection of subunits of cyclic AMP-dependent protein kinase into cardiac myocytes modulates Ca2+ current. Nature (1982) 2.33
Expression of matrix-metalloproteinases and their inhibitors in the wounds of diabetic and non-diabetic patients. Diabetologia (2002) 2.32
Modulation of Ca current during the phosphorylation cycle in the guinea pig heart. Pflugers Arch (1986) 2.26
The potassium current underlying delayed rectification in cat ventricular muscle. J Physiol (1978) 2.24
Different beta-subunits determine G-protein interaction with transmembrane receptors. Nature (1992) 2.23
Receptor-mediated regulation of the nonselective cation channels TRPC4 and TRPC5. J Biol Chem (2000) 2.22
A note on the pacemaker current in Purkinje fibers. Pflugers Arch (1969) 2.20
Calcium conductance and tension in mammalian ventricular muscle. Pflugers Arch (1975) 2.17
Analysis of the acute and chronic wound environments: the role of proteases and their inhibitors. Wound Repair Regen (2000) 2.15
Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents. Nature (1991) 2.15
Excitatory membrane current in heart muscle (Purkinje fibers). Pflugers Arch Gesamte Physiol Menschen Tiere (1966) 2.15
Sodium nitroprusside and other smooth muscle-relaxants increase cyclic GMP levels in rat ductus deferens. Nature (1977) 2.15
The potassium component of membrane current in Purkinje fibers. Pflugers Arch Gesamte Physiol Menschen Tiere (1967) 2.14
Sensitizing soluble guanylyl cyclase to become a highly CO-sensitive enzyme. EMBO J (1996) 2.13
The structural implications of the linear electrical properties of cardiac Purkinje strands. J Gen Physiol (1970) 2.06
Effects of a protein phosphatase inhibitor, okadaic acid, on membrane currents of isolated guinea-pig cardiac myocytes. Pflugers Arch (1988) 2.05
Morphological, biochemical, and electrophysiological characterization of a clonal cell (H9c2) line from rat heart. Circ Res (1991) 1.99
Cloning and functional expression of a human Ca2+-permeable cation channel activated by calcium store depletion. Neuron (1996) 1.99
Slow inward current and action potential in cardiac Purkinje fibres. The effect of Mn plus,plus-ions. Pflugers Arch (1971) 1.97
Expression of TRPC3 in Chinese hamster ovary cells results in calcium-activated cation currents not related to store depletion. J Cell Biol (1997) 1.96
Relaxation of the ACh-induced potassium current in the rabbit sinoatrial node cell. Pflugers Arch (1978) 1.96
Brain nitric oxide synthase is a biopterin- and flavin-containing multi-functional oxido-reductase. FEBS Lett (1991) 1.96
Fast and slow gating behaviour of single calcium channels in cardiac cells. Relation to activation and inactivation of calcium-channel current. Pflugers Arch (1986) 1.95
The effect of tetrodotoxin on the membrane current in cardiac muscle (Purkinje fibers). Pflugers Arch Gesamte Physiol Menschen Tiere (1967) 1.95
On the mechanism of muscarinic inhibition of the cardiac Ca current. Pflugers Arch (1986) 1.95
Voltage-dependent properties of macroscopic and elementary calcium channel currents in guinea pig ventricular myocytes. Pflugers Arch (1986) 1.93
The effect of dihydro-ouabain and lithium-ions on the outward current in cardiac Purkinje fibers. Evidence for electrogenicity of active transport. Pflugers Arch (1974) 1.91
Tocopherol and plastoquinone synthesis in spinach chloroplasts subfractions. Arch Biochem Biophys (1980) 1.90
Beta-adrenergic increase in the calcium conductance of cardiac myocytes studied with the patch clamp. Pflugers Arch (1984) 1.90
Does the organic calcium channel blocker D600 act from inside or outside on the cardiac cell membrane? Pflugers Arch (1982) 1.90
Involvement of pyrimidinoceptors in the regulation of cell functions by uridine and by uracil nucleotides. Trends Pharmacol Sci (1989) 1.88
"Run-down" of the Ca current during long whole-cell recordings in guinea pig heart cells: role of phosphorylation and intracellular calcium. Pflugers Arch (1988) 1.87
Localization and synthesis of prenylquinones in isolated outer and inner envelope membranes from spinach chloroplasts. Arch Biochem Biophys (1985) 1.86
Calcium currents in single SA nodal cells of the rabbit heart studied with action potential clamp. Pflugers Arch (1989) 1.82
G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets. Proc Natl Acad Sci U S A (1994) 1.77
Five-minute treatments with fluorouracil, floxuridine, and mitomycin have long-term effects on human Tenon's capsule fibroblasts. Arch Ophthalmol (1992) 1.74
Activation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets. J Cell Biol (1999) 1.72
The importance of calcium ions for the regulation of guanosine 3':5'-cyclic monophosphage levels. Proc Natl Acad Sci U S A (1973) 1.72
A membrane current related to the plateau of the action potential of Purkinje fibers. Pflugers Arch (1968) 1.71
Selectivity in signal transduction determined by gamma subunits of heterotrimeric G proteins. Science (1993) 1.71
Early ribosomal RNA transcription and appearance of cytoplasmic ribosomes during germination of the wheat embryo. Nat New Biol (1971) 1.68
Kinetics and magnitude of the time-dependent potassium current in the rabbit sinoatrial node: effect of external potassium. Pflugers Arch (1979) 1.68
Stimulation of humoral antibody formation by polyanions. 3. Restoration of the immune response to sheep red blood cells by polyanions in thymectomized and lethally irradiated mice protected with bone marrow cells. Eur J Immunol (1971) 1.66
On the mechanism of the negative inotropic effect of acetylcholine. Pflugers Arch (1976) 1.66
Receptors and G proteins as primary components of transmembrane signal transduction. Part 1. G-protein-coupled receptors: structure and function. J Mol Med (Berl) (1995) 1.65
Pyruvate-Derived Amino Acids in Spinach Chloroplasts : Synthesis and Regulation during Photosynthetic Carbon Metabolism. Plant Physiol (1984) 1.63
Identification of GTP-binding proteins in the plasma membrane of higher plants. Biochem Biophys Res Commun (1988) 1.60
Purification of soluble guanylyl cyclase from bovine lung by a new immunoaffinity chromatographic method. Eur J Biochem (1990) 1.60
Mutation of His-105 in the beta 1 subunit yields a nitric oxide-insensitive form of soluble guanylyl cyclase. Proc Natl Acad Sci U S A (1994) 1.58
Diversity and selectivity of receptor-G protein interaction. Annu Rev Pharmacol Toxicol (1996) 1.58
Stimulation of healing of chronic wounds by epidermal growth factor. Plast Reconstr Surg (1991) 1.57
The effect of intracellular cyclic nucleotides and calcium on the action potential and acetylcholine response of isolated cardiac cells. Pflugers Arch (1982) 1.56
Soluble guanylate cyclase purified from bovine lung contains heme and copper. FEBS Lett (1981) 1.55
Reduction of adenylate cyclase activity in lysates of human platelets by the alpha-adrenergic component of epinephrine. J Cyclic Nucleotide Res (1977) 1.54
Membrane currents in cat myocardium: separation of inward and outward components. J Physiol (1978) 1.53
Plastidic Isoprenoid Synthesis during Chloroplast Development : Change from Metabolic Autonomy to a Division-of-Labor Stage. Plant Physiol (1990) 1.53
The G-protein G13 but not G12 mediates signaling from lysophosphatidic acid receptor via epidermal growth factor receptor to Rho. J Biol Chem (1998) 1.53
YC-1 potentiates nitric oxide- and carbon monoxide-induced cyclic GMP effects in human platelets. Mol Pharmacol (1998) 1.49
Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic, acid-stimulated mitogenic activity in L cells. Proc Natl Acad Sci U S A (1998) 1.47
Protein kinase A anchoring proteins are required for vasopressin-mediated translocation of aquaporin-2 into cell membranes of renal principal cells. J Biol Chem (1999) 1.45
Differential involvement of Galpha12 and Galpha13 in receptor-mediated stress fiber formation. J Biol Chem (1999) 1.44
Ionic currents contributing to the action potential in single ventricular myocytes of the guinea pig studied with action potential clamp. Pflugers Arch (1990) 1.42
Vasopressin-induced von Willebrand factor secretion from endothelial cells involves V2 receptors and cAMP. J Clin Invest (2000) 1.41
Biofilm maturity studies indicate sharp debridement opens a time- dependent therapeutic window. J Wound Care (2010) 1.39
Moyamoya-like vasculopathy from cocaine dependency. AJNR Am J Neuroradiol (2000) 1.38
Pleiotropic effects of Pasteurella multocida toxin are mediated by Gq-dependent and -independent mechanisms. involvement of Gq but not G11. J Biol Chem (2000) 1.38
A new enzymatic assay for guanosine 3':5'-cyclic monophosphate and its application to the ductus deferens of the rat. Proc Natl Acad Sci U S A (1973) 1.37
The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families. Proc Natl Acad Sci U S A (1996) 1.35
A dileucine sequence and an upstream glutamate residue in the intracellular carboxyl terminus of the vasopressin V2 receptor are essential for cell surface transport in COS.M6 cells. Mol Pharmacol (1998) 1.34
Uncoupling of alpha-adrenoceptor-mediated inhibition of human platelet adenylate cyclase by N-ethylmaleimide. J Biol Chem (1982) 1.32
The dependence of cardiac contraction on depolarization and slow inward current. Pflugers Arch (1971) 1.32
X-linked nephrogenic diabetes insipidus mutations in North America and the Hopewell hypothesis. J Clin Invest (1993) 1.31
Hydrogenation of geranylgeraniol : two pathways exist in spinach chloroplasts. Plant Physiol (1983) 1.31
Prolonged localized tissue effects from 5-minute exposures to fluorouracil and mitomycin C. Arch Ophthalmol (1993) 1.31
Cat ventricular muscle treated with D600: characteristics of calcium channel block and unblock. J Physiol (1984) 1.30
Nature and recurrence of AVPR2 mutations in X-linked nephrogenic diabetes insipidus. Am J Hum Genet (1994) 1.30
Transfected muscarinic acetylcholine receptors selectively couple to Gi-type G proteins and Gq/11. Mol Pharmacol (1994) 1.30
Role for G(12)/G(13) in agonist-induced vascular smooth muscle cell contraction. Circ Res (2000) 1.28
Purification of a soluble, sodium-nitroprusside-stimulated guanylate cyclase from bovine lung. Eur J Biochem (1981) 1.28
Current-voltage relations in ventricular muscle preparations from different species. Pflugers Arch (1978) 1.27