The effect of dihydro-ouabain and lithium-ions on the outward current in cardiac Purkinje fibers. Evidence for electrogenicity of active transport.

PubWeight™: 1.91‹?› | Rank: Top 3%

🔗 View Article (PMID 4859532)

Published in Pflugers Arch on January 01, 1974

Authors

G Isenberg, W Trautwein

Articles citing this

The surprising heart: a review of recent progress in cardiac electrophysiology. J Physiol (1984) 3.18

Transient inward current underlying arrhythmogenic effects of cardiotonic steroids in Purkinje fibres. J Physiol (1976) 2.78

Relationship between internal calcium and outward current in mammalian ventricular muscle; a mechanism for the control of the action potential duration? J Physiol (1976) 2.32

Inotropic and arrhythmogenic effects of potassium-depleted solutions on mammalian cardiac muscle. J Physiol (1979) 2.28

Characterization of the electrogenic sodium pump in cardiac Purkinje fibres. J Physiol (1980) 1.96

Membrane current through adenosine-triphosphate-regulated potassium channels in guinea-pig ventricular cells. J Physiol (1985) 1.71

An analysis of the actions of low concentrations of ouabain on membrane currents in Purkinje fibres. J Physiol (1976) 1.71

Measurement and significance of the reversal potential for the pace-maker current (iK2) in sheep Purkinje fibres. J Physiol (1979) 1.60

The role of the sodium pump in the effects of potassium-depleted solutions on mammalian cardiac muscle. J Physiol (1979) 1.56

Properties of an electrogenic sodium-potassium pump in isolated canine Purkinje myocytes. J Physiol (1987) 1.49

Direct measurement of changes in sodium pump current in canine cardiac Purkinje fibers. Proc Natl Acad Sci U S A (1979) 1.39

Isoprenaline, Ca2+ and the Na(+)-K+ pump in guinea-pig ventricular myocytes. J Physiol (1992) 1.30

The electrogenic sodium pump in guinea-pig ventricular muscle: inhibition of pump current by cardiac glycosides. J Physiol (1982) 1.20

Changes in the electrical activity of dog cardiac Purkinje fibres at high heart rates. J Physiol (1984) 1.20

The interactions of protons, calcium and potassium ions on cardiac Purkinje fibres. J Physiol (1978) 1.19

The effects of heart rate on the action potential of guinea-pig and human ventricular muscle. J Physiol (1981) 1.12

Incorporation of membrane potential into theoretical analysis of electrogenic ion pumps. Proc Natl Acad Sci U S A (1985) 1.08

The effects of the Anemonia sulcata toxin (ATX II) on membrane currents of isolated mammalian myocytes. J Physiol (1984) 1.07

Stimulation of cardiac alpha receptors increases Na/K pump current and decreases gK via a pertussis toxin-sensitive pathway. Biophys J (1988) 1.03

A study of pace-maker potential in rabbit sino-atrial node: measurement of potassium activity under voltage-clamp conditions. J Physiol (1981) 0.99

The effects of beta-stimulation on the Na(+)-K+ pump current-voltage relationship in guinea-pig ventricular myocytes. J Physiol (1996) 0.98

The effects of membrane potential on active and passive sodium transport in Xenopus oocytes. J Physiol (1987) 0.93

The effect of strophanthidin on action potential, calcium current and contraction in isolated guinea-pig ventricular myocytes. J Physiol (1991) 0.91

Simultaneous measurement of changes in current and tracer flux in voltage-clamped squid giant axon. Biophys J (1989) 0.90

Indirect effects of acetylcholine on the electrogenic sodium pump in bull-frog atrial muscle fibres. J Physiol (1988) 0.85

Quaternary organic amines inhibit Na,K pump current in a voltage-dependent manner: direct evidence of an extracellular access channel in the Na,K-ATPase. J Gen Physiol (2004) 0.85

Ouabain-resistant hyperpolarization induced by insulin in aggregates of embryonic heart cells. Proc Natl Acad Sci U S A (1980) 0.82

Heart muscle. Intracellular potassium and inward-going rectification. Biophys J (1981) 0.81

Proceedings: Functional hyperaemia in soleus muscle of the cat. J Physiol (1975) 0.81

Arrhythmogenic interaction between low potassium and ouabain in isolated guinea-pig ventricular myocytes. J Physiol (1988) 0.80

The Plastic Glial-Synaptic Dynamics within the Neuropil: A Self-Organizing System Composed of Polyelectrolytes in Phase Transition. Neural Plast (2016) 0.78

Relevance of excitable media theory and retinal spreading depression experiments in preclinical pharmacological research. Curr Neuropharmacol (2014) 0.76

Inhibition of the Na pump--a mechanism in the genesis of cardiac arrhythmias. Basic Res Cardiol (1985) 0.75

Analysis of the hyperpolarizing effect of catecholamines on canine cardiac Purkinje fibres. Br J Pharmacol (1989) 0.75

Articles by these authors

(truncated to the top 100)

Calcium tolerant ventricular myocytes prepared by preincubation in a "KB medium". Pflugers Arch (1982) 6.81

Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells. Physiol Rev (1994) 5.51

Superresolution three-dimensional images of fluorescence in cells with minimal light exposure. Science (1995) 4.16

Polarity of actin at the leading edge of cultured cells. Nature (1978) 3.40

Acetylcholine activation of single muscarinic K+ channels in isolated pacemaker cells of the mammalian heart. Nature (1983) 3.34

The GTP-binding protein, Go, regulates neuronal calcium channels. Nature (1987) 3.24

Action potentials and net membrane currents of isolated smooth muscle cells (urinary bladder of the guinea-pig). Pflugers Arch (1985) 3.12

Elementary currents through Ca2+ channels in guinea pig myocytes. Pflugers Arch (1983) 3.10

An actin-binding protein from Acanthamoeba regulates actin filament polymerization and interactions. Nature (1980) 3.04

On the mechanism of beta-adrenergic regulation of the Ca channel in the guinea-pig heart. Pflugers Arch (1985) 2.93

The dynamic chloride component of membrane current in Purkinje fibers. Pflugers Arch Gesamte Physiol Menschen Tiere (1967) 2.90

Inward membrane currents in mammalian myocardium. Pflugers Arch (1972) 2.84

Interaction of alpha-actinin and vinculin with actin: opposite effects on filament network formation. Proc Natl Acad Sci U S A (1981) 2.84

The ionic nature of slow inward current and its relation to contraction. Pflugers Arch (1972) 2.70

Cardiac Purkinje fibers: cesium as a tool to block inward rectifying potassium currents. Pflugers Arch (1976) 2.69

Calcium currents of isolated bovine ventricular myocytes are fast and of large amplitude. Pflugers Arch (1982) 2.69

The effect of the duration of the action potential on contraction in the mammalian heart muscle. Pflugers Arch Gesamte Physiol Menschen Tiere (1968) 2.68

Purified dihydropyridine-binding site from skeletal muscle t-tubules is a functional calcium channel. Nature (1986) 2.41

Depletion and accumulation of potassium in the extracellular clefts of cardiac Purkinje fibers during voltage clamp hyperpolarization and depolarization. Pflugers Arch (1977) 2.36

Injection of subunits of cyclic AMP-dependent protein kinase into cardiac myocytes modulates Ca2+ current. Nature (1982) 2.33

Intracellular calcium ions modulate acetylcholine-induced inward current in guinea-pig ileum. J Physiol (1990) 2.31

Modulation of Ca current during the phosphorylation cycle in the guinea pig heart. Pflugers Arch (1986) 2.26

The potassium current underlying delayed rectification in cat ventricular muscle. J Physiol (1978) 2.24

A note on the pacemaker current in Purkinje fibers. Pflugers Arch (1969) 2.20

Calcium conductance and tension in mammalian ventricular muscle. Pflugers Arch (1975) 2.17

Excitatory membrane current in heart muscle (Purkinje fibers). Pflugers Arch Gesamte Physiol Menschen Tiere (1966) 2.15

Calcium currents of cesium loaded isolated smooth muscle cells (urinary bladder of the guinea pig). Pflugers Arch (1985) 2.14

The potassium component of membrane current in Purkinje fibers. Pflugers Arch Gesamte Physiol Menschen Tiere (1967) 2.14

The structural implications of the linear electrical properties of cardiac Purkinje strands. J Gen Physiol (1970) 2.06

Effects of a protein phosphatase inhibitor, okadaic acid, on membrane currents of isolated guinea-pig cardiac myocytes. Pflugers Arch (1988) 2.05

Effect of membrane potential on acetylcholine-induced inward current in guinea-pig ileum. J Physiol (1990) 2.02

Slow inward current and action potential in cardiac Purkinje fibres. The effect of Mn plus,plus-ions. Pflugers Arch (1971) 1.97

Relaxation of the ACh-induced potassium current in the rabbit sinoatrial node cell. Pflugers Arch (1978) 1.96

Fast and slow gating behaviour of single calcium channels in cardiac cells. Relation to activation and inactivation of calcium-channel current. Pflugers Arch (1986) 1.95

The effect of tetrodotoxin on the membrane current in cardiac muscle (Purkinje fibers). Pflugers Arch Gesamte Physiol Menschen Tiere (1967) 1.95

On the mechanism of muscarinic inhibition of the cardiac Ca current. Pflugers Arch (1986) 1.95

Voltage-dependent properties of macroscopic and elementary calcium channel currents in guinea pig ventricular myocytes. Pflugers Arch (1986) 1.93

Beta-adrenergic increase in the calcium conductance of cardiac myocytes studied with the patch clamp. Pflugers Arch (1984) 1.90

Does the organic calcium channel blocker D600 act from inside or outside on the cardiac cell membrane? Pflugers Arch (1982) 1.90

"Run-down" of the Ca current during long whole-cell recordings in guinea pig heart cells: role of phosphorylation and intracellular calcium. Pflugers Arch (1988) 1.87

Isolated atrial myocytes: adenosine and acetylcholine increase potassium conductance. Am J Physiol (1983) 1.86

Cytoplasmic actomyosin fibrils in tissue culture cells: direct proof of contractility by visualization of ATP-induced contraction in fibrils isolated by laser micro-beam dissection. Cell Tissue Res (1976) 1.84

Calcium currents in single SA nodal cells of the rabbit heart studied with action potential clamp. Pflugers Arch (1989) 1.82

Total and free myoplasmic calcium during a contraction cycle: x-ray microanalysis in guinea-pig ventricular myocytes. J Physiol (1991) 1.79

Membrane potential modulates inositol 1,4,5-trisphosphate-mediated Ca2+ transients in guinea-pig coronary myocytes. J Physiol (1993) 1.77

Acetylcholine activates nonselective cation channels in guinea pig ileum through a G protein. Am J Physiol (1990) 1.77

Contribution of Ca(2+)-induced Ca2+ release to the [Ca2+]i transients in myocytes from guinea-pig urinary bladder. J Physiol (1992) 1.75

Depolarization-mediated intracellular calcium transients in isolated smooth muscle cells of guinea-pig urinary bladder. J Physiol (1991) 1.74

Contribution of two types of calcium channels to membrane conductance of single myocytes from guinea-pig coronary artery. J Physiol (1990) 1.72

Ca2+ load of guinea-pig ventricular myocytes determines efficacy of brief Ca2+ currents as trigger for Ca2+ release. J Physiol (1994) 1.71

A membrane current related to the plateau of the action potential of Purkinje fibers. Pflugers Arch (1968) 1.71

Ca2+ activation and Ca2+ inactivation of canine reconstituted cardiac sarcoplasmic reticulum Ca(2+)-release channels. J Physiol (1995) 1.71

New actin-binding proteins from Dictyostelium discoideum. EMBO J (1984) 1.68

Kinetics and magnitude of the time-dependent potassium current in the rabbit sinoatrial node: effect of external potassium. Pflugers Arch (1979) 1.68

On the mechanism of the negative inotropic effect of acetylcholine. Pflugers Arch (1976) 1.66

Decoupling of heart muscle cells: correlation with increased cytoplasmic calcium activity and with changes of nexus ultrastructure. J Membr Biol (1980) 1.58

Cardiac Purkinje fibres: [Ca2+]i controls the potassium permeability via the conductance components gK1 and gK2. Pflugers Arch (1977) 1.57

Selection of Dictyostelium mutants defective in cytoskeletal proteins: use of an antibody that binds to the ends of alpha-actinin rods. EMBO J (1986) 1.56

The effect of intracellular cyclic nucleotides and calcium on the action potential and acetylcholine response of isolated cardiac cells. Pflugers Arch (1982) 1.56

Membrane currents in cat myocardium: separation of inward and outward components. J Physiol (1978) 1.53

Gating of maxi K+ channels studied by Ca2+ concentration jumps in excised inside-out multi-channel patches (myocytes from guinea pig urinary bladder). J Gen Physiol (1992) 1.52

Disruption of microfilament organization after injection of F-actin capping proteins into living tissue culture cells. Nature (1983) 1.49

Microheterogeneity of subsarcolemmal sodium gradients. Electron probe microanalysis in guinea-pig ventricular myocytes. J Physiol (1993) 1.46

Ionic currents contributing to the action potential in single ventricular myocytes of the guinea pig studied with action potential clamp. Pflugers Arch (1990) 1.42

Crystalline actin sheets: their structure and polymorphism. J Cell Biol (1981) 1.40

A Dictyostelium mutant deficient in severin, an F-actin fragmenting protein, shows normal motility and chemotaxis. J Cell Biol (1989) 1.40

Intracellular [Ca2+] transients in voltage clamped cardiac Purkinje fibers. Pflugers Arch (1982) 1.39

Cardiac Purkinje fibres: [Ca2+]i controls steady state potassium conductance. Pflugers Arch (1977) 1.39

Actions of adenosine and isoproterenol on isolated mammalian ventricular myocytes. Circ Res (1983) 1.37

The viscoelasticity of entangled actin networks: the influence of defects and modulation by talin and vinculin. Eur Biophys J (1993) 1.36

Glycocalyx is not required for show inward calcium current in isolated rat heart myocytes. Nature (1980) 1.36

Structural aspects of vinculin-actin interactions. J Mol Biol (1982) 1.35

Ca2+ influx through ATP-gated channels increments [Ca2+]i and inactivates ICa in myocytes from guinea-pig urinary bladder. J Physiol (1991) 1.34

Intracellular pH modulates the availability of vascular L-type Ca2+ channels. J Gen Physiol (1994) 1.32

The dependence of cardiac contraction on depolarization and slow inward current. Pflugers Arch (1971) 1.32

Cat ventricular muscle treated with D600: characteristics of calcium channel block and unblock. J Physiol (1984) 1.30

Ca entry and contraction as studied in isolated bovine ventricular myocytes. Z Naturforsch C (1982) 1.30

Calcium channel current of vascular smooth muscle cells: extracellular protons modulate gating and single channel conductance. J Gen Physiol (1994) 1.29

Endothelin depolarizes myocytes from porcine coronary and human mesenteric arteries through a Ca-activated chloride current. Pflugers Arch (1991) 1.29

Current-voltage relations in ventricular muscle preparations from different species. Pflugers Arch (1978) 1.27

The shortening of the action potential by DNP in guinea-pig ventricular myocytes is mediated by an increase of a time-independent K conductance. Pflugers Arch (1983) 1.27

K efflux through inward rectifying K channels in voltage clamped Purkinje fibers. Pflugers Arch (1980) 1.27

Analysis of filamin and alpha-actinin binding to actin by the stopped flow method. FEBS Lett (1993) 1.25

The role of sodium channels in the effects of the cardiotonic compound DPI 201-106 on contractility and membrane potentials in isolated mammalian heart preparations. Eur J Pharmacol (1985) 1.25

Injection of catalytic subunit of cAMP-dependent protein kinase into isolated cardiac myocytes. Pflugers Arch (1983) 1.24

A Dictyostelium mutant lacking an F-actin cross-linking protein, the 120-kD gelation factor. J Cell Biol (1990) 1.24

Talin anchors and nucleates actin filaments at lipid membranes. A direct demonstration. FEBS Lett (1992) 1.22

Temperature-induced transitory and steady-state changes in the calcium current of guinea pig ventricular myocytes. Pflugers Arch (1985) 1.22

Experimental approach to test the role of actin in axonal transport. Brain Res (1980) 1.21

Cardiac Purkinje fibres: resting, action, and pacemaker potential under the influence of [Ca2+]i as modified by intracellular injection techniques. Pflugers Arch (1977) 1.20

Potentiation by cyclic GMP of beta-adrenergic effect on Ca2+ current in guinea-pig ventricular cells. J Physiol (1991) 1.20

Native talin is a dumbbell-shaped homodimer when it interacts with actin. J Struct Biol (1994) 1.20

X-ray microanalysis of single cardiac myocytes frozen under voltage-clamp conditions. Am J Physiol (1989) 1.19

Stretch-activated currents in ventricular myocytes: amplitude and arrhythmogenic effects increase with hypertrophy. Cardiovasc Res (2000) 1.19

Modification of L-type calcium current by intracellularly applied trypsin in guinea-pig ventricular myocytes. J Physiol (1988) 1.19

Actin filament capping protein from bovine brain. EMBO J (1982) 1.18

On the mechanism of slow calcium channel block in heart. Pflugers Arch (1980) 1.18

Ionic basis for the antagonism between adenosine and isoproterenol on isolated mammalian ventricular myocytes. Circ Res (1984) 1.18

Talin binds to actin and promotes filament nucleation. FEBS Lett (1991) 1.17

Effect of tetrodotoxin on membrane currents in mammalian cardiac fibres. Nature (1967) 1.17