Published in Gastroenterology on February 25, 2014
The secretin/secretin receptor axis modulates liver fibrosis through changes in transforming growth factor-β1 biliary secretion in mice. Hepatology (2016) 1.45
E2F8 as a Novel Therapeutic Target for Lung Cancer. J Natl Cancer Inst (2015) 0.91
Post-translational regulation of the type III inositol 1,4,5-trisphosphate receptor by miRNA-506. J Biol Chem (2014) 0.83
Inhibition of mast cell-derived histamine secretion by cromolyn sodium treatment decreases biliary hyperplasia in cholestatic rodents. Lab Invest (2014) 0.82
Functional and structural features of cholangiocytes in health and disease. Cell Mol Gastroenterol Hepatol (2015) 0.79
MicroRNAs and benign biliary tract diseases. Semin Liver Dis (2015) 0.78
Regulators of Cholangiocyte Proliferation. Gene Expr (2016) 0.77
Bile acid signaling and biliary functions. Acta Pharm Sin B (2015) 0.77
Development and functional characterization of extrahepatic cholangiocyte lines from normal rats. Dig Liver Dis (2015) 0.76
Knockout of microRNA-21 reduces biliary hyperplasia and liver fibrosis in cholestatic bile duct ligated mice. Lab Invest (2016) 0.76
Substance P increases liver fibrosis by differential changes in senescence of cholangiocytes and hepatic stellate cells. Hepatology (2017) 0.75
Bile duct ligation-induced biliary hyperplasia, hepatic injury, and fibrosis are reduced in mast cell-deficient Kit(W-sh) mice. Hepatology (2017) 0.75
Gonadotropin-releasing hormone stimulates biliary proliferation by paracrine/autocrine mechanisms. Am J Pathol (2015) 0.75
Lin28 and let-7: roles and regulation in liver diseases. Am J Physiol Gastrointest Liver Physiol (2016) 0.75
Knockdown of Hepatic Gonadotropin-Releasing Hormone by Vivo-Morpholino Decreases Liver Fibrosis in Multidrug Resistance Gene 2 Knockout Mice by Down-Regulation of miR-200b. Am J Pathol (2017) 0.75
Human MicroRNA targets. PLoS Biol (2004) 34.51
Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. Gastroenterology (2006) 7.06
Stem cell-like micro-RNA signature driven by Myc in aggressive liver cancer. Proc Natl Acad Sci U S A (2010) 2.91
A cellular micro-RNA, let-7i, regulates Toll-like receptor 4 expression and contributes to cholangiocyte immune responses against Cryptosporidium parvum infection. J Biol Chem (2007) 2.89
The cholangiopathies: disorders of biliary epithelia. Gastroenterology (2004) 2.38
Biliary physiology in rats with bile ductular cell hyperplasia. Evidence for a secretory function of proliferated bile ductules. J Clin Invest (1988) 2.11
Proliferating cholangiocytes: a neuroendocrine compartment in the diseased liver. Gastroenterology (2006) 1.98
Vascular endothelial growth factor stimulates rat cholangiocyte proliferation via an autocrine mechanism. Gastroenterology (2006) 1.86
Morphological, molecular, and functional heterogeneity of cholangiocytes from normal rat liver. Gastroenterology (1996) 1.76
Heterogeneity of the proliferative capacity of rat cholangiocytes after bile duct ligation. Am J Physiol (1998) 1.68
The basic helix-loop-helix transcription factor BETA2/NeuroD is expressed in mammalian enteroendocrine cells and activates secretin gene expression. Proc Natl Acad Sci U S A (1997) 1.57
Small mouse cholangiocytes proliferate in response to H1 histamine receptor stimulation by activation of the IP3/CaMK I/CREB pathway. Am J Physiol Cell Physiol (2008) 1.57
Morphological and functional heterogeneity of the mouse intrahepatic biliary epithelium. Lab Invest (2009) 1.45
Large but not small intrahepatic bile ducts are involved in secretin-regulated ductal bile secretion. Am J Physiol (1997) 1.42
Acute carbon tetrachloride feeding induces damage of large but not small cholangiocytes from BDL rat liver. Am J Physiol (1999) 1.42
Evaluation of differential gene expression by microarray analysis in small and large cholangiocytes isolated from normal mice. Liver Int (2003) 1.42
Primary biliary cirrhosis is associated with altered hepatic microRNA expression. J Autoimmun (2009) 1.41
Cholinergic system modulates growth, apoptosis, and secretion of cholangiocytes from bile duct-ligated rats. Gastroenterology (1999) 1.39
Up-regulation of microRNA 506 leads to decreased Cl-/HCO3- anion exchanger 2 expression in biliary epithelium of patients with primary biliary cirrhosis. Hepatology (2012) 1.38
A mouse model of cholestasis-associated cholangiocarcinoma and transcription factors involved in progression. Gastroenterology (2011) 1.29
Cell proliferation and oncogene expression after bile duct ligation in the rat: evidence of a specific growth effect on bile duct cells. Hepatology (1995) 1.27
Upregulation of secretin receptor gene expression in rat cholangiocytes after bile duct ligation. Am J Physiol (1994) 1.27
Nerve growth factor modulates the proliferative capacity of the intrahepatic biliary epithelium in experimental cholestasis. Gastroenterology (2004) 1.24
Regulation of placenta growth factor by microRNA-125b in hepatocellular cancer. J Hepatol (2011) 1.20
Knockout of secretin receptor reduces large cholangiocyte hyperplasia in mice with extrahepatic cholestasis induced by bile duct ligation. Hepatology (2010) 1.17
The biliary HCO(3)(-) umbrella: a unifying hypothesis on pathogenetic and therapeutic aspects of fibrosing cholangiopathies. Hepatology (2010) 1.16
After damage of large bile ducts by gamma-aminobutyric acid, small ducts replenish the biliary tree by amplification of calcium-dependent signaling and de novo acquisition of large cholangiocyte phenotypes. Am J Pathol (2010) 1.13
Secretin inhibits cholangiocarcinoma growth via dysregulation of the cAMP-dependent signaling mechanisms of secretin receptor. Int J Cancer (2010) 1.12
A biliary HCO3- umbrella constitutes a protective mechanism against bile acid-induced injury in human cholangiocytes. Hepatology (2012) 1.11
Administration of r-VEGF-A prevents hepatic artery ligation-induced bile duct damage in bile duct ligated rats. Am J Physiol Gastrointest Liver Physiol (2006) 1.08
Identification of endogenous reference genes for RT-qPCR analysis of plasma microRNAs levels in rats with acetaminophen-induced hepatotoxicity. J Appl Toxicol (2013) 1.07
Immunofluorescent localization of secretin and enteroglucagon in human intestinal mucosa. Scand J Gastroenterol (1971) 1.04
The C-terminus ends of secretin and VIP interact with the N-terminal domains of their receptors. Peptides (1996) 1.04
Assessment of biliary bicarbonate secretion in humans by positron emission tomography. Gastroenterology (1999) 0.96
Melatonin exerts by an autocrine loop antiproliferative effects in cholangiocarcinoma: its synthesis is reduced favoring cholangiocarcinoma growth. Am J Physiol Gastrointest Liver Physiol (2011) 0.94
Role of stem cell factor and granulocyte colony-stimulating factor in remodeling during liver regeneration. Hepatology (2012) 0.94
An indispensable role of secretin in mediating the osmoregulatory functions of angiotensin II. FASEB J (2010) 0.93
Abnormal gastric motility in liver cirrhosis: roles of secretin. Dig Dis Sci (1998) 0.89
Modulation of the biliary expression of arylalkylamine N-acetyltransferase alters the autocrine proliferative responses of cholangiocytes in rats. Hepatology (2013) 0.88
Molecular basis and species specificity of high affinity binding of vasoactive intestinal polypeptide by the rat secretin receptor. J Pharmacol Exp Ther (1996) 0.85
GABA induces the differentiation of small into large cholangiocytes by activation of Ca(2+) /CaMK I-dependent adenylyl cyclase 8. Hepatology (2013) 0.84
Apotopes and innate immune system: novel players in the primary biliary cirrhosis scenario. Dig Liver Dis (2013) 0.84
Neural control of the release and action of secretin. J Physiol Pharmacol (2003) 0.82
Presence and possible site of action of secretin in the rat pituitary and hypothalamus. Life Sci (1984) 0.78
Modulation of secretin release by neuropeptides in secretin-producing cells. Am J Physiol (1998) 0.78
Evidence on the presence of secretin cells in the gastric antral and oxyntic mucosa. Regul Pept (2003) 0.77
Experimental studies on the influence of simultaneous ligation of the bile and pancreatic ducts upon gastric acid secretion and gut hormones. Tohoku J Exp Med (1986) 0.77
Endocrine cells in the human common bile duct in patients with obstructive jaundice. Hepatogastroenterology (2012) 0.76
The biliary epithelium presents antigens to and activates natural killer T cells. Hepatology (2015) 1.52
The secretin/secretin receptor axis modulates liver fibrosis through changes in transforming growth factor-β1 biliary secretion in mice. Hepatology (2016) 1.45
Activation of biliary tree stem cells within peribiliary glands in primary sclerosing cholangitis. J Hepatol (2015) 1.41
The critical role of myeloid-derived suppressor cells and FXR activation in immune-mediated liver injury. J Autoimmun (2014) 0.81
Forkhead box A2 regulated biliary heterogeneity and senescence during cholestatic liver injury. Hepatology (2016) 0.75
Lin28 and let-7: roles and regulation in liver diseases. Am J Physiol Gastrointest Liver Physiol (2016) 0.75
Gonadotropin-releasing hormone stimulates biliary proliferation by paracrine/autocrine mechanisms. Am J Pathol (2015) 0.75