Published in J Biol Chem on July 27, 2007
Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21. Nat Immunol (2009) 5.05
The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs. Immunity (2009) 3.58
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MicroRNA-98 and let-7 regulate expression of suppressor of cytokine signaling 4 in biliary epithelial cells in response to Cryptosporidium parvum infection. J Infect Dis (2010) 1.04
Suppression of microRNA activity amplifies IFN-γ-induced macrophage activation and promotes anti-tumour immunity. Nat Cell Biol (2016) 1.02
Toll-like receptor-4 (TLR4) down-regulates microRNA-107, increasing macrophage adhesion via cyclin-dependent kinase 6. J Biol Chem (2011) 1.01
miR-27b targets KSRP to coordinate TLR4-mediated epithelial defense against Cryptosporidium parvum infection. PLoS Pathog (2012) 1.01
Cryptosporidium parvum induces B7-H1 expression in cholangiocytes by down-regulating microRNA-513. J Infect Dis (2010) 1.01
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Functional implications of microRNA-215 in TGF-β1-induced phenotypic transition of mesangial cells by targeting CTNNBIP1. PLoS One (2013) 0.99
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MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus. PLoS Genet (2013) 0.99
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miR-20b, miR-98, miR-125b-1*, and let-7e* as new potential diagnostic biomarkers in ulcerative colitis. World J Gastroenterol (2013) 0.97
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Let-7 in cardiovascular diseases, heart development and cardiovascular differentiation from stem cells. Int J Mol Sci (2013) 0.96
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Small RNA-mediated regulation of host-pathogen interactions. Virulence (2013) 0.96
MicroRNA-221 controls expression of intercellular adhesion molecule-1 in epithelial cells in response to Cryptosporidium parvum infection. Int J Parasitol (2011) 0.95
miR-30b, down-regulated in gastric cancer, promotes apoptosis and suppresses tumor growth by targeting plasminogen activator inhibitor-1. PLoS One (2014) 0.95
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Secretin stimulates biliary cell proliferation by regulating expression of microRNA 125b and microRNA let7a in mice. Gastroenterology (2014) 0.95
Histone deacetylases and NF-kB signaling coordinate expression of CX3CL1 in epithelial cells in response to microbial challenge by suppressing miR-424 and miR-503. PLoS One (2013) 0.94
Understanding Alcoholism Through microRNA Signatures in Brains of Human Alcoholics. Front Genet (2012) 0.94
Aberrant expression of microRNAs in T cells from patients with ankylosing spondylitis contributes to the immunopathogenesis. Clin Exp Immunol (2013) 0.93
Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress. Proc Natl Acad Sci U S A (2015) 0.93
Respiratory syncytial virus regulates human microRNAs by using mechanisms involving beta interferon and NF-κB. MBio (2012) 0.93
MicroRNA-146a represses mycobacteria-induced inflammatory response and facilitates bacterial replication via targeting IRAK-1 and TRAF-6. PLoS One (2013) 0.93
TLR4 promotes Cryptosporidium parvum clearance in a mouse model of biliary cryptosporidiosis. J Parasitol (2011) 0.93
HIV Tat induces expression of ICAM-1 in HUVECs: implications for miR-221/-222 in HIV-associated cardiomyopathy. PLoS One (2013) 0.92
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MicroRNAs of parasites: current status and future perspectives. Parasitol Res (2010) 0.92
Differential microRNA expression in experimental cerebral and noncerebral malaria. Infect Immun (2011) 0.91
HIV-1 Tat protein suppresses cholangiocyte toll-like receptor 4 expression and defense against Cryptosporidium parvum. J Infect Dis (2009) 0.91
Decreased expression of microRNA let-7i and its association with chemotherapeutic response in human gastric cancer. World J Surg Oncol (2012) 0.91
MicroRNAs and Epithelial Immunity. Int Rev Immunol (2009) 0.90
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Role of miRNA let-7 and its major targets in prostate cancer. Biomed Res Int (2014) 0.89
Molecular mechanisms of regulation of Toll-like receptor signaling. J Leukoc Biol (2016) 0.89
Let-7b is involved in the inflammation and immune responses associated with Helicobacter pylori infection by targeting Toll-like receptor 4. PLoS One (2013) 0.88
Boswellic acid exerts antitumor effects in colorectal cancer cells by modulating expression of the let-7 and miR-200 microRNA family. Carcinogenesis (2012) 0.88
Role of innate immunity in the development of hepatocellular carcinoma. World J Gastroenterol (2013) 0.87
MicroRNA-34c is associated with emphysema severity and modulates SERPINE1 expression. BMC Genomics (2014) 0.85
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Regulation of microRNA by hepatitis B virus infection and their possible association with control of innate immunity. World J Gastroenterol (2014) 0.84
Cyclooxygenase-2 is a target of microRNA-16 in human hepatoma cells. PLoS One (2012) 0.83
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A newly identified microRNA, mmu-miR-7578, functions as a negative regulator on inflammatory cytokines tumor necrosis factor-α and interleukin-6 via targeting Egr1 in vivo. J Biol Chem (2012) 0.83
Release of Small RNA-containing Exosome-like Vesicles from the Human Filarial Parasite Brugia malayi. PLoS Negl Trop Dis (2015) 0.83
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c-Myc-regulated microRNAs modulate E2F1 expression. Nature (2005) 31.81
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NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci U S A (2006) 21.58
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Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science (2005) 16.84
A pancreatic islet-specific microRNA regulates insulin secretion. Nature (2004) 15.02
A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis. Cell (2005) 9.22
A cellular microRNA mediates antiviral defense in human cells. Science (2005) 8.48
Stem cell division is regulated by the microRNA pathway. Nature (2005) 7.79
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Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells. Proc Natl Acad Sci U S A (2005) 5.88
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Multiple TLRs are expressed in human cholangiocytes and mediate host epithelial defense responses to Cryptosporidium parvum via activation of NF-kappaB. J Immunol (2005) 1.88
Impaired production of proinflammatory cytokines and host resistance to acute infection with Trypanosoma cruzi in mice lacking functional myeloid differentiation factor 88. J Immunol (2004) 1.50
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Down-regulation of the tumor suppressor PTEN by the tumor necrosis factor-alpha/nuclear factor-kappaB (NF-kappaB)-inducing kinase/NF-kappaB pathway is linked to a default IkappaB-alpha autoregulatory loop. J Biol Chem (2003) 1.45
Cryptosporidium parvum activates nuclear factor kappaB in biliary epithelia preventing epithelial cell apoptosis. Gastroenterology (2001) 1.36
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Peptide antibiotic human beta-defensin-1 and -2 contribute to antimicrobial defense of the intrahepatic biliary tree. Hepatology (2004) 1.11
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MicroRNAs: key modulators of posttranscriptional gene expression. Gastroenterology (2008) 1.16
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Development and characterization of a cholangiocyte cell line from the PCK rat, an animal model of Autosomal Recessive Polycystic Kidney Disease. Lab Invest (2006) 1.12
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HDAC6 inhibition restores ciliary expression and decreases tumor growth. Cancer Res (2013) 1.11
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Cholangiocyte N-Ras protein mediates lipopolysaccharide-induced interleukin 6 secretion and proliferation. J Biol Chem (2011) 1.07
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Phosphatidylinositol 3-kinase and frabin mediate Cryptosporidium parvum cellular invasion via activation of Cdc42. J Biol Chem (2004) 1.04
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Inhibition of Cdc25A suppresses hepato-renal cystogenesis in rodent models of polycystic kidney and liver disease. Gastroenterology (2011) 1.00
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Cryptosporidium parvum attachment to and internalization by human biliary epithelia in vitro: a morphologic study. J Parasitol (2004) 0.97
TGR5 in the Cholangiociliopathies. Dig Dis (2015) 0.97
Localized glucose and water influx facilitates Cryptosporidium parvum cellular invasion by means of modulation of host-cell membrane protrusion. Proc Natl Acad Sci U S A (2005) 0.97
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Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling. Am J Physiol Gastrointest Liver Physiol (2013) 0.94
Somatostatin stimulates ductal bile absorption and inhibits ductal bile secretion in mice via SSTR2 on cholangiocytes. Am J Physiol Cell Physiol (2003) 0.93
Aquaporin-8 is involved in water transport in isolated superficial colonocytes from rat proximal colon. J Nutr (2005) 0.93
TLR4 promotes Cryptosporidium parvum clearance in a mouse model of biliary cryptosporidiosis. J Parasitol (2011) 0.93
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Cdc42 and the actin-related protein/neural Wiskott-Aldrich syndrome protein network mediate cellular invasion by Cryptosporidium parvum. Infect Immun (2004) 0.91
Bile formation: do not ignore the role of plasma membrane-cytoskeleton linking proteins. Hepatology (2003) 0.90
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Cytoskeletal and motor proteins facilitate trafficking of AQP1-containing vesicles in cholangiocytes. Biol Cell (2006) 0.90
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Expression and subcellular localization of aquaporin water channels in the polarized hepatocyte cell line, WIF-B. BMC Physiol (2005) 0.87
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