Mechanism of IRSp53 inhibition and combinatorial activation by Cdc42 and downstream effectors.

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Published in Nat Struct Mol Biol on March 02, 2014

Authors

David J Kast1, Changsong Yang2, Andrea Disanza3, Malgorzata Boczkowska1, Yadaiah Madasu1, Giorgio Scita4, Tatyana Svitkina2, Roberto Dominguez1

Author Affiliations

1: Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
2: Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
3: FIRC Institute of Molecular Oncology, Milan, Italy.
4: 1] FIRC Institute of Molecular Oncology, Milan, Italy. [2] Department of Health Sciences, University of Milan School of Medicine, Milan, Italy.

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