Published in PLoS Biol on February 25, 2014
FMN2 Makes Perinuclear Actin to Protect Nuclei during Confined Migration and Promote Metastasis. Cell (2016) 1.46
DNA damage induces nuclear actin filament assembly by Formin-2 and Spire-½ that promotes efficient DNA repair. Elife (2015) 1.03
A mitochondria-anchored isoform of the actin-nucleating spire protein regulates mitochondrial division. Elife (2015) 0.99
Self-organization of protrusions and polarity during eukaryotic chemotaxis. Curr Opin Cell Biol (2014) 0.94
RhoA-mediated FMNL1 regulates GM130 for actin assembly and phosphorylates MAPK for spindle formation in mouse oocyte meiosis. Cell Cycle (2015) 0.89
Control of polarized assembly of actin filaments in cell motility. Cell Mol Life Sci (2015) 0.88
The WH2 Domain and Actin Nucleation: Necessary but Insufficient. Trends Biochem Sci (2016) 0.87
The bacterial virulence factors VopL and VopF nucleate actin from the pointed end. J Cell Biol (2017) 0.81
Roles of actin binding proteins in mammalian oocyte maturation and beyond. Cell Cycle (2016) 0.78
Small molecule inhibitor of formin homology 2 domains (SMIFH2) reveals the roles of the formin family of proteins in spindle assembly and asymmetric division in mouse oocytes. PLoS One (2015) 0.78
Membrane targeting of the Spir·formin actin nucleator complex requires a sequential handshake of polar interactions. J Biol Chem (2015) 0.77
Structure of a Bud6/Actin Complex Reveals a Novel WH2-like Actin Monomer Recruitment Motif. Structure (2015) 0.77
Single-filament kinetic studies provide novel insights into regulation of actin-based motility. Mol Biol Cell (2016) 0.77
Impact of cordon-bleu expression on actin cytoskeleton architecture and dynamics. Cytoskeleton (Hoboken) (2016) 0.76
Single Filaments to Reveal the Multiple Flavors of Actin. Biophys J (2016) 0.76
Drosophila comes of age as a model system for understanding the function of cytoskeletal proteins in cells, tissues, and organisms. Cytoskeleton (Hoboken) (2015) 0.76
Copy number variation analysis detects novel candidate genes involved in follicular growth and oocyte maturation in a cohort of premature ovarian failure cases. Hum Reprod (2016) 0.75
Global treadmilling coordinates actin turnover and controls the size of actin networks. Nat Rev Mol Cell Biol (2017) 0.75
Ping-pong positioning: alternating protein interactions at actin filament barbed ends helps establish polarity in mammalian oocytes. PLoS Biol (2014) 0.75
A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion. PLoS One (2016) 0.75
Role of the C-terminal Extension of Formin 2 in Its Activation by Spire Protein and Processive Assembly of Actin Filaments. J Biol Chem (2015) 0.75
The kinetics of enzyme-catalyzed reactions with two or more substrates or products. I. Nomenclature and rate equations. Biochim Biophys Acta (1963) 14.92
Mechanism and function of formins in the control of actin assembly. Annu Rev Biochem (2007) 5.36
An actin nucleation mechanism mediated by Bni1 and profilin. Nat Cell Biol (2002) 4.52
Control of the assembly of ATP- and ADP-actin by formins and profilin. Cell (2006) 4.37
How profilin promotes actin filament assembly in the presence of thymosin beta 4. Cell (1993) 4.20
Formin is a processive motor that requires profilin to accelerate actin assembly and associated ATP hydrolysis. Cell (2004) 4.01
Drosophila Spire is an actin nucleation factor. Nature (2005) 3.64
The fission yeast cytokinesis formin Cdc12p is a barbed end actin filament capping protein gated by profilin. J Cell Biol (2003) 3.40
Formin-2, polyploidy, hypofertility and positioning of the meiotic spindle in mouse oocytes. Nat Cell Biol (2002) 3.34
Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain. Nature (2005) 3.31
Self-organization of MTOCs replaces centrosome function during acentrosomal spindle assembly in live mouse oocytes. Cell (2007) 2.99
Bni1p and Bnr1p: downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae. EMBO J (1997) 2.80
Individual actin filaments in a microfluidic flow reveal the mechanism of ATP hydrolysis and give insight into the properties of profilin. PLoS Biol (2011) 2.59
Actin polymerization and ATP hydrolysis. Science (1987) 2.42
A new model for asymmetric spindle positioning in mouse oocytes. Curr Biol (2008) 2.32
INF2 Is a WASP homology 2 motif-containing formin that severs actin filaments and accelerates both polymerization and depolymerization. J Biol Chem (2006) 2.28
Regulatory interactions between two actin nucleators, Spire and Cappuccino. J Cell Biol (2007) 2.08
How capping protein binds the barbed end of the actin filament. Curr Biol (2003) 2.05
Spindle positioning in mouse oocytes relies on a dynamic meshwork of actin filaments. Curr Biol (2008) 1.97
Model of formin-associated actin filament elongation. Mol Cell (2006) 1.92
Vesicles modulate an actin network for asymmetric spindle positioning. Nat Cell Biol (2013) 1.92
Rotational movement of the formin mDia1 along the double helical strand of an actin filament. Science (2010) 1.87
Asymmetric division in mouse oocytes: with or without Mos. Curr Biol (2000) 1.84
An actin-dependent mechanism for long-range vesicle transport. Nat Cell Biol (2011) 1.80
Spire-type actin nucleators cooperate with Formin-2 to drive asymmetric oocyte division. Curr Biol (2011) 1.79
Capu and Spire assemble a cytoplasmic actin mesh that maintains microtubule organization in the Drosophila oocyte. Dev Cell (2007) 1.78
Evidence for an ATP cap at the ends of actin filaments and its regulation of the F-actin steady state. J Biol Chem (1984) 1.75
Interaction of thymosin beta 4 with muscle and platelet actin: implications for actin sequestration in resting platelets. Biochemistry (1992) 1.73
Actin-driven chromosomal motility leads to symmetry breaking in mammalian meiotic oocytes. Nat Cell Biol (2008) 1.65
Coordination of microtubule and microfilament dynamics by Drosophila Rho1, Spire and Cappuccino. Nat Cell Biol (2006) 1.65
Analysis of the function of Spire in actin assembly and its synergy with formin and profilin. Mol Cell (2007) 1.57
The Spir actin organizers are involved in vesicle transport processes. Curr Biol (2001) 1.45
Profilin is required for posterior patterning of the Drosophila oocyte. Development (1996) 1.43
Structure and function of the interacting domains of Spire and Fmn-family formins. Proc Natl Acad Sci U S A (2011) 1.36
Spire contains actin binding domains and is related to ascidian posterior end mark-5. Development (1999) 1.29
How ATP hydrolysis controls filament assembly from profilin-actin: implication for formin processivity. J Biol Chem (2007) 1.26
The C terminus of formin FMNL3 accelerates actin polymerization and contains a WH2 domain-like sequence that binds both monomers and filament barbed ends. J Biol Chem (2011) 1.24
Formin mDia1 senses and generates mechanical forces on actin filaments. Nat Commun (2013) 1.23
Acentrosomal spindle assembly and chromosome segregation during oocyte meiosis. Trends Cell Biol (2012) 1.22
Actin cytoskeleton in cell polarity and asymmetric division during mouse oocyte maturation. Cytoskeleton (Hoboken) (2012) 1.18
Identification of a short Spir interaction sequence at the C-terminal end of formin subgroup proteins. J Biol Chem (2009) 1.18
Symmetry breaking in mouse oocytes requires transient F-actin meshwork destabilization. Development (2011) 1.17
Overlapping expression pattern of the actin organizers Spir-1 and formin-2 in the developing mouse nervous system and the adult brain. Gene Expr Patterns (2004) 1.16
Discrimination of ATP, ADP, and AMPPNP by chaperonin GroEL: hexokinase treatment revealed the exclusive role of ATP. J Biol Chem (2003) 1.14
Actin filament barbed end elongation with nonmuscle MgATP-actin and MgADP-actin in the presence of profilin. Biochemistry (2002) 1.12
Confinement induces actin flow in a meiotic cytoplasm. Proc Natl Acad Sci U S A (2012) 1.07
Intermittent depolymerization of actin filaments is caused by photo-induced dimerization of actin protomers. Proc Natl Acad Sci U S A (2012) 1.07
Molecular basis of actin nucleation factor cooperativity: crystal structure of the Spir-1 kinase non-catalytic C-lobe domain (KIND)•formin-2 formin SPIR interaction motif (FSI) complex. J Biol Chem (2011) 1.05
Human spire interacts with the barbed end of the actin filament. J Mol Biol (2011) 1.04
Dimeric WH2 domains in Vibrio VopF promote actin filament barbed-end uncapping and assisted elongation. Nat Struct Mol Biol (2013) 1.03
Direct interaction between two actin nucleators is required in Drosophila oogenesis. Development (2013) 1.03
Sequential actin-based pushing forces drive meiosis I chromosome migration and symmetry breaking in oocytes. J Cell Biol (2013) 0.97
A soft cortex is essential for asymmetric spindle positioning in mouse oocytes. Nat Cell Biol (2013) 0.96
Actin monomers activate inverted formin 2 by competing with its autoinhibitory interaction. J Biol Chem (2013) 0.96
Autoinhibition of the formin Cappuccino in the absence of canonical autoinhibitory domains. Mol Biol Cell (2012) 0.91
Spindle positioning in mammalian oocytes. Exp Cell Res (2012) 0.90