Published in Cell on November 10, 2016
The assembly and function of perinuclear actin cap in migrating cells. Protoplasma (2017) 0.81
Bursting the Bubble - Nuclear Envelope Rupture as a Path to Genomic Instability? Trends Cell Biol (2017) 0.76
Cancer cell motility: lessons from migration in confined spaces. Nat Rev Cancer (2016) 0.76
Cell migration: Caged for protection. Nat Rev Cancer (2016) 0.75
Septin 9_i2 is downregulated in tumors, impairs cancer cell migration and alters subnuclear actin filaments. Sci Rep (2017) 0.75
Actomyosin drives cancer cell nuclear dysmorphia and threatens genome stability. Nat Commun (2017) 0.75
Astrocytes from the brain microenvironment alter migration and morphology of metastatic breast cancer cells. FASEB J (2017) 0.75
Role of liver ICAM-1 in metastasis. Oncol Lett (2017) 0.75
PQN-75 is expressed in the pharyngeal gland cells of Caenorhabditiselegans and is dispensable for germline development. Biol Open (2017) 0.75
Cell migration: integrating signals from front to back. Science (2003) 29.13
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem (1998) 28.13
Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia. J Cell Biol (1999) 8.24
A tense situation: forcing tumour progression. Nat Rev Cancer (2009) 7.80
p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks. J Cell Biol (2000) 7.26
Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure. Proc Natl Acad Sci U S A (1997) 7.24
Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. J Cell Biol (2006) 6.52
Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. Nat Cell Biol (2007) 6.15
Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression. Nat Med (2011) 5.54
Stress fibers are generated by two distinct actin assembly mechanisms in motile cells. J Cell Biol (2006) 5.54
A nucleator arms race: cellular control of actin assembly. Nat Rev Mol Cell Biol (2010) 5.33
Selection of successive tumour lines for metastasis. Nat New Biol (1973) 5.03
Nuclear movement regulated by Cdc42, MRCK, myosin, and actin flow establishes MTOC polarization in migrating cells. Cell (2005) 4.86
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation. Nat Cell Biol (2011) 4.59
More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance. Nat Cell Biol (2011) 4.23
Chromothripsis from DNA damage in micronuclei. Nature (2015) 4.04
Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation. J Cell Biol (2010) 3.56
Formin-2, polyploidy, hypofertility and positioning of the meiotic spindle in mouse oocytes. Nat Cell Biol (2002) 3.34
The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis. Trends Cell Biol (2001) 3.22
Regulation of dendritic cell migration by CD74, the MHC class II-associated invariant chain. Science (2008) 2.88
Noninvasive assessment of collagen gel microstructure and mechanics using multiphoton microscopy. Biophys J (2006) 2.71
Nuclear envelope rupture and repair during cancer cell migration. Science (2016) 2.60
Decreased mechanical stiffness in LMNA-/- cells is caused by defective nucleo-cytoskeletal integrity: implications for the development of laminopathies. Hum Mol Genet (2004) 2.42
Nuclear mechanics during cell migration. Curr Opin Cell Biol (2010) 2.32
ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death. Science (2016) 2.30
The interaction between nesprins and sun proteins at the nuclear envelope is critical for force transmission between the nucleus and cytoskeleton. J Biol Chem (2011) 2.21
Nuclear actin network assembly by formins regulates the SRF coactivator MAL. Science (2013) 2.13
Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival. J Cell Biol (2014) 2.01
Spatial coordination between cell and nuclear shape within micropatterned endothelial cells. Nat Commun (2012) 1.96
Catastrophic nuclear envelope collapse in cancer cell micronuclei. Cell (2013) 1.89
Local cortical tension by myosin II guides 3D endothelial cell branching. Curr Biol (2009) 1.85
ATR mediates a checkpoint at the nuclear envelope in response to mechanical stress. Cell (2014) 1.73
Vinculin-actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth. J Cell Biol (2013) 1.63
Spire and Formin 2 synergize and antagonize in regulating actin assembly in meiosis by a ping-pong mechanism. PLoS Biol (2014) 1.62
Fifteen formins for an actin filament: a molecular view on the regulation of human formins. Biochim Biophys Acta (2010) 1.56
Direct in vivo RNAi screen unveils myosin IIa as a tumor suppressor of squamous cell carcinomas. Science (2014) 1.53
The Structural Basis of Actin Organization by Vinculin and Metavinculin. J Mol Biol (2015) 1.50
Chromothripsis and Kataegis Induced by Telomere Crisis. Cell (2015) 1.49
Structure and function of the interacting domains of Spire and Fmn-family formins. Proc Natl Acad Sci U S A (2011) 1.36
Modes of cancer cell invasion and the role of the microenvironment. Curr Opin Cell Biol (2015) 1.32
53BP1 and the LINC Complex Promote Microtubule-Dependent DSB Mobility and DNA Repair. Cell (2015) 1.29
FibrilTool, an ImageJ plug-in to quantify fibrillar structures in raw microscopy images. Nat Protoc (2014) 1.28
Nuclear deformability constitutes a rate-limiting step during cell migration in 3-D environments. Cell Mol Bioeng (2014) 1.24
Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments. Nat Commun (2016) 1.13
Keeping the LINC: the importance of nucleocytoskeletal coupling in intracellular force transmission and cellular function. Biochem Soc Trans (2011) 1.11
Metastasis as an evolutionary process. Science (2016) 1.11
DNA damage induces nuclear actin filament assembly by Formin-2 and Spire-½ that promotes efficient DNA repair. Elife (2015) 1.03
Cell migration in confinement: a micro-channel-based assay. Methods Mol Biol (2011) 1.02
Formin-2, a novel formin homology protein of the cappuccino subfamily, is highly expressed in the developing and adult central nervous system. Mech Dev (2000) 1.01
Mutations to the formin homology 2 domain of INF2 protein have unexpected effects on actin polymerization and severing. J Biol Chem (2012) 0.99
Identification and functional characterization of FMN2, a regulator of the cyclin-dependent kinase inhibitor p21. Mol Cell (2013) 0.97
The nuclear γ-H2AX apoptotic ring: implications for cancers and autoimmune diseases. Cell Mol Life Sci (2014) 0.93
Biallelic truncating mutations in FMN2, encoding the actin-regulatory protein Formin 2, cause nonsyndromic autosomal-recessive intellectual disability. Am J Hum Genet (2014) 0.93
Specification of Architecture and Function of Actin Structures by Actin Nucleation Factors. Annu Rev Biophys (2015) 0.92
DNA damage-induced cell death: lessons from the central nervous system. Cell Res (2008) 0.91
Symmetry breaking and polarity establishment during mouse oocyte maturation. Philos Trans R Soc Lond B Biol Sci (2013) 0.91
Distinctive properties of metastasis-initiating cells. Genes Dev (2016) 0.91
Gene profiling of Graffi murine leukemia virus-induced lymphoid leukemias: identification of leukemia markers and Fmn2 as a potential oncogene. Blood (2010) 0.89
Activation of myosin in HeLa cells causes redistribution of focal adhesions and F-actin from cell center to cell periphery. Cell Motil Cytoskeleton (2006) 0.89
Mechanical interplay between invadopodia and the nucleus in cultured cancer cells. Sci Rep (2015) 0.89
Genome-wide association and fine mapping of genetic loci predisposing to colon carcinogenesis in mice. Mol Cancer Res (2011) 0.89
Metastasis suppressor microRNA-335 targets the formin family of actin nucleators. PLoS One (2013) 0.87
Inverted formin 2 in focal adhesions promotes dorsal stress fiber and fibrillar adhesion formation to drive extracellular matrix assembly. Proc Natl Acad Sci U S A (2015) 0.87
ATM and ATR signaling at a glance. J Cell Sci (2015) 0.85
Inhibition of Cdc42-interacting protein 4 (CIP4) impairs osteosarcoma tumor progression. Curr Cancer Drug Targets (2013) 0.83
Polarity gene alterations in pure invasive micropapillary carcinomas of the breast. Breast Cancer Res (2014) 0.80
De novo deletion of FMN2 in a girl with mild non-syndromic intellectual disability. Eur J Med Genet (2013) 0.78
Genome-wide copy number analysis in a family with p.G533C RET mutation and medullary thyroid carcinoma identified regions potentially associated with a higher predisposition to lymph node metastasis. J Clin Endocrinol Metab (2014) 0.76
Study of dendritic cell migration using micro-fabrication. J Immunol Methods (2015) 0.75