Published in J Exp Med on November 01, 1988
Cell-mediated immunity to Bordetella pertussis: role of Th1 cells in bacterial clearance in a murine respiratory infection model. Infect Immun (1993) 3.04
Human T cell clones define S1 subunit as the most immunogenic moiety of pertussis toxin and determine its epitope map. J Exp Med (1989) 1.49
Proliferative responses and gamma interferon and tumor necrosis factor production by lymphocytes isolated from tracheobroncheal lymph nodes and spleen of mice aerosol infected with Bordetella pertussis. Infect Immun (1992) 1.16
Interaction of the pertussis toxin peptide containing residues 30-42 with DR1 and the T-cell receptors of 12 human T-cell clones. Proc Natl Acad Sci U S A (1992) 1.12
Identification of human T-cell epitopes on the S4 subunit of pertussis toxin. Infect Immun (1992) 0.82
Identification of murine T-cell epitopes on the S4 subunit of pertussis toxin. Infect Immun (1993) 0.79
Further analysis of the sequence of the S1 subunit of pertussis toxin. Infect Immun (1991) 0.75
Prediction of protein antigenic determinants from amino acid sequences. Proc Natl Acad Sci U S A (1981) 32.98
Prediction of the secondary structure of proteins from their amino acid sequence. Adv Enzymol Relat Areas Mol Biol (1978) 29.77
Mouse Protection Tests in the Study of Pertussis Vaccine: A Comparative Series Using the Intracerebral Route for Challenge. Am J Public Health Nations Health (1947) 15.54
Pertussis immunisation and serious acute neurological illness in children. Br Med J (Clin Res Ed) (1981) 8.48
Binding of immunogenic peptides to Ia histocompatibility molecules. Nature (1985) 8.39
Nature and rates of adverse reactions associated with DTP and DT immunizations in infants and children. Pediatrics (1981) 7.58
Pertussis toxin gene: nucleotide sequence and genetic organization. Science (1986) 6.02
Cloning and sequencing of the pertussis toxin genes: operon structure and gene duplication. Proc Natl Acad Sci U S A (1986) 5.59
Molecular mimicry and autoimmune disease. Cell (1987) 5.31
T-cell antigenic sites tend to be amphipathic structures. Proc Natl Acad Sci U S A (1985) 5.05
T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis. Nature (1987) 3.96
Development of a pertussis component vaccine in Japan. Lancet (1984) 3.94
Bordetella pertussis infection in mice: correlation of specific antibodies against two antigens, pertussis toxin, and filamentous hemagglutinin with mouse protectivity in an intracerebral or aerosol challenge system. Infect Immun (1984) 2.72
Expression and immunological properties of the five subunits of pertussis toxin. Infect Immun (1987) 2.59
Individual versus public priorities in the determination of optimal vaccination policies. Am J Epidemiol (1986) 2.55
Islets-activating protein (IAP) in Bordetella pertussis that potentiates insulin secretory responses of rats. Purification and characterization. J Biochem (1978) 2.26
Construction of synthetic immunogen: use of new T-helper epitope on malaria circumsporozoite protein. Science (1987) 2.24
Comparison of pertussis cultures by mouse protection and virulence tests . Am J Public Health Nations Health (1949) 2.15
Use of gelatin/plasma coated flasks for isolating human peripheral blood monocytes. J Immunol Methods (1983) 2.12
Bordetella pertussis toxins. Pharmacol Ther (1982) 1.93
ADP-ribosyltransferase activity of pertussis toxin and immunomodulation by Bordetella pertussis. Science (1988) 1.57
Possible role of V beta T cell receptor genes in susceptibility to collagen-induced arthritis in mice. J Exp Med (1988) 1.55
In vitro immune responsiveness to vaccinea virus and HLA. N Engl J Med (1977) 1.43
The atomic mobility component of protein antigenicity. Annu Rev Immunol (1985) 1.40
Constraints in T-B cooperation related to epitope topology on E. coli beta-galactosidase. I. The fine specificity of T cells dictates the fine specificity of antibodies directed to conformation-dependent determinants. Eur J Immunol (1985) 1.40
Pertussis toxin is required for pertussis vaccine encephalopathy. Proc Natl Acad Sci U S A (1985) 1.31
The specificity of cellular immune responses in guinea pigs. III. The precision of antigen recognition by T lymphocytes. J Exp Med (1976) 1.22
HLA-linked genes controlling immune response and disease susceptibility. Immunol Rev (1983) 1.17
Distribution of labeled lymph node cells in mice during the lymphocytosis induced by Bordetella pertussis. J Exp Med (1972) 1.14
Use of synthetic peptides to map antigenic sites of Bordetella pertussis toxin subunit S1. J Infect Dis (1988) 0.94
Antigen-presenting cells in human decidual tissue. Am J Reprod Immunol Microbiol (1986) 0.86
Modulation of carrier-induced epitopic suppression by Bordetella pertussis components and muramyl peptide. Cell Immunol (1987) 0.85
Vaccines for the future--an update. Immunol Cell Biol (1987) 0.78
Comparative genomics of BCG vaccines by whole-genome DNA microarray. Science (1999) 17.48
The epidemiology of tuberculosis in San Francisco. A population-based study using conventional and molecular methods. N Engl J Med (1994) 16.32
An outbreak of tuberculosis with accelerated progression among persons infected with the human immunodeficiency virus. An analysis using restriction-fragment-length polymorphisms. N Engl J Med (1992) 13.29
Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases. Cancer Res (1999) 10.65
Exogenous reinfection with multidrug-resistant Mycobacterium tuberculosis in patients with advanced HIV infection. N Engl J Med (1993) 7.85
Regulation of the Mycobacterium tuberculosis hypoxic response gene encoding alpha -crystallin. Proc Natl Acad Sci U S A (2001) 7.65
Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin. Nature (1992) 7.20
Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE). J Immunol (1996) 6.44
An inducible bundle-forming pilus of enteropathogenic Escherichia coli. Science (1991) 6.25
An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control. Curr Biol (2001) 6.15
The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters. Proc Natl Acad Sci U S A (2000) 5.81
Vibrio cholerae O1 El Tor: identification of a gene cluster required for the rugose colony type, exopolysaccharide production, chlorine resistance, and biofilm formation. Proc Natl Acad Sci U S A (1999) 5.76
Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention. Cell (1988) 5.73
Gonococci causing disseminated gonococcal infection are resistant to the bactericidal action of normal human sera. J Clin Invest (1976) 5.54
Type IV pili, transient bacterial aggregates, and virulence of enteropathogenic Escherichia coli. Science (1998) 5.49
The T lymphocyte in experimental allergic encephalomyelitis. Annu Rev Immunol (1990) 5.36
Class restriction of cephalosporin use to control total cephalosporin resistance in nosocomial Klebsiella. JAMA (1998) 5.20
The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science (2001) 4.89
The Mycobacterium tuberculosis ECF sigma factor sigmaE: role in global gene expression and survival in macrophages. Mol Microbiol (2001) 4.60
Exploring drug-induced alterations in gene expression in Mycobacterium tuberculosis by microarray hybridization. Proc Natl Acad Sci U S A (1999) 4.33
Hirschsprung disease, associated syndromes and genetics: a review. J Med Genet (2007) 4.13
Molecular strain typing of Mycobacterium tuberculosis to confirm cross-contamination in the mycobacteriology laboratory and modification of procedures to minimize occurrence of false-positive cultures. J Clin Microbiol (1993) 4.05
T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis. Nature (1987) 3.96
A molecular basis for MHC class II--associated autoimmunity. Science (1988) 3.75
T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination. Nature (1985) 3.71
Mycobacterium tuberculosis gene expression during adaptation to stationary phase and low-oxygen dormancy. Tuberculosis (Edinb) (2004) 3.70
Detection of Shigella in feces using DNA amplification. J Infect Dis (1990) 3.61
High-resolution mapping of serovar-specific and common antigenic determinants of the major outer membrane protein of Chlamydia trachomatis. J Exp Med (1988) 3.55
Polyarginine enters cells more efficiently than other polycationic homopolymers. J Pept Res (2000) 3.41
Gonococcal pili. Primary structure and receptor binding domain. J Exp Med (1984) 3.32
Limited heterogeneity of rearranged T-cell receptor V alpha transcripts in brains of multiple sclerosis patients. Nature (1990) 3.30
Multiple sclerosis: a two-stage disease. Nat Immunol (2001) 3.20
Skp2 is oncogenic and overexpressed in human cancers. Proc Natl Acad Sci U S A (2001) 2.98
Cloning and characterization of bfpTVW, genes required for the transcriptional activation of bfpA in enteropathogenic Escherichia coli. Mol Microbiol (1996) 2.96
Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy. Cell (1989) 2.77
VpsR, a Member of the Response Regulators of the Two-Component Regulatory Systems, Is Required for Expression of vps Biosynthesis Genes and EPS(ETr)-Associated Phenotypes in Vibrio cholerae O1 El Tor. J Bacteriol (2001) 2.77
Global experience in cervical carotid artery stent placement. Catheter Cardiovasc Interv (2000) 2.77
HLA class II allelic variation and susceptibility to pemphigus vulgaris. Proc Natl Acad Sci U S A (1988) 2.72
Strain-specific and common epitopes of gonococcal pili. J Exp Med (1984) 2.72
The two-dimensional IR nonlinear spectroscopy of a cyclic penta-peptide in relation to its three-dimensional structure. Proc Natl Acad Sci U S A (1999) 2.70
A stationary-phase stress-response sigma factor from Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (1996) 2.70
Reversal of experimental allergic encephalomyelitis with monoclonal antibody to a T-cell subset marker. Science (1985) 2.68
Multi-gene amplification: simultaneous detection of three virulence genes in diarrhoeal stool. Mol Microbiol (1989) 2.65
Role of rpoS in stress survival and virulence of Vibrio cholerae. J Bacteriol (1998) 2.65
Intragenic recombination in a flagellin gene: characterization of the H1-j gene of Salmonella typhi. EMBO J (1989) 2.38
Ultrastructural localization of specific gonococcal macromolecules with antibody-gold sphere immunological probes. Infect Immun (1984) 2.31
Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein. Nature (1996) 2.30
Mannose-sensitive and Gal-Gal binding Escherichia coli pili from recombinant strains. Chemical, functional, and serological properties. J Exp Med (1983) 2.27
Normal dystrophin transcripts detected in Duchenne muscular dystrophy patients after myoblast transplantation. Nature (1992) 2.22
A pilus peptide vaccine for the prevention of gonorrhea. Prog Allergy (1983) 2.19
An unexpected version of horror autotoxicus: anaphylactic shock to a self-peptide. Nat Immunol (2001) 2.10
The bundle-forming pili of enteropathogenic Escherichia coli: transcriptional regulation by environmental signals. Mol Microbiol (1996) 2.08
Enteropathogenic Escherichia coli: identification of a gene cluster coding for bundle-forming pilus morphogenesis. J Bacteriol (1996) 2.08
Genetic studies on Neisseria gonorrhoeae from disseminated gonococcal infections. Infect Immun (1977) 2.08
T cell recognition as the target for immune intervention in autoimmune disease. Cell (1989) 2.04
Differential susceptibility of plasma proteins to oxidative modification: examination by western blot immunoassay. Free Radic Biol Med (1994) 2.03
In vivo effects of antibodies to immune response gene products: prevention of experimental allergic encephalitis. Proc Natl Acad Sci U S A (1981) 2.00
Current global status of carotid artery stent placement. Cathet Cardiovasc Diagn (1998) 1.99
Antibodies to CD44 and integrin alpha4, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment. Proc Natl Acad Sci U S A (1999) 1.98
Complete DNA sequence and structural analysis of the enteropathogenic Escherichia coli adherence factor plasmid. Infect Immun (1999) 1.98
Manpower requirements when implementing a partial shift system for anaesthetic juniors. Anaesthesia (2002) 1.93
Unique sequences in region VI of the flagellin gene of Salmonella typhi. Mol Microbiol (1989) 1.90
Predominant expression of a T cell receptor V beta gene subfamily in autoimmune encephalomyelitis. J Exp Med (1988) 1.89
Localized adherence by enteropathogenic Escherichia coli is an inducible phenotype associated with the expression of new outer membrane proteins. J Exp Med (1991) 1.87
Pilin-gene phase variation of Moraxella bovis is caused by an inversion of the pilin genes. J Bacteriol (1988) 1.86
Sequence, localization and function of the invasin protein of Yersinia enterocolitica. Mol Microbiol (1990) 1.84
Modulation of MHC class II antigen expression in human myoblasts after treatment with IFN-gamma. Neurology (1991) 1.83
Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T cell clones correlates with encephalitogenicity. Int Immunol (1990) 1.83
Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteases. J Clin Invest (1994) 1.82
Three-dimensional structure of cholera toxin penetrating a lipid membrane. Science (1988) 1.81
The invasin protein of Yersinia enterocolitica: internalization of invasin-bearing bacteria by eukaryotic cells is associated with reorganization of the cytoskeleton. J Cell Biol (1992) 1.81
CD4+ T-cell subsets in autoimmunity. Curr Opin Immunol (1997) 1.78
HLA-A2 peptides can regulate cytolysis by human allogeneic T lymphocytes. Nature (1988) 1.78
Isolation and sequence of the structural gene for cytochrome c oxidase subunit VI from Saccharomyces cerevisiae. J Biol Chem (1984) 1.76
Serum IL-17F does not predict poor response to IM IFNβ-1a in relapsing-remitting MS. Neurology (2012) 1.76
The Staphylococcus aureus rsbW (orf159) gene encodes an anti-sigma factor of SigB. J Bacteriol (1999) 1.71
Cloning and characterization of the bundle-forming pilin gene of enteropathogenic Escherichia coli and its distribution in Salmonella serotypes. Mol Microbiol (1993) 1.71
Plasmid-encoded expression of lipopolysaccharide O-antigenic polysaccharide in enteropathogenic Escherichia coli. Infect Immun (1987) 1.69
Characterizing the mechanisms of progression in multiple sclerosis: evidence and new hypotheses for future directions. Arch Neurol (2005) 1.69
GFAP mutations, age at onset, and clinical subtypes in Alexander disease. Neurology (2011) 1.69
Regulation of disease susceptibility: decreased prevalence of IgE-mediated allergic disease in patients with multiple sclerosis. J Allergy Clin Immunol (1996) 1.68
Regulation of the Mycobacterium tuberculosis PE/PPE genes. Tuberculosis (Edinb) (2004) 1.67
Nuclear functions required for cytochrome c oxidase biogenesis in Saccharomyces cerevisiae. Characterization of mutants in 34 complementation groups. J Biol Chem (1986) 1.67
Gene microarray identification of redox and mitochondrial elements that control resistance or sensitivity to apoptosis. Proc Natl Acad Sci U S A (2000) 1.60
Induction of relapsing paralysis in experimental autoimmune encephalomyelitis by bacterial superantigen. Nature (1993) 1.60
Purification and characterization of Haemophilus influenzae pili, and their structural and serological relatedness to Escherichia coli P and mannose-sensitive pili. J Exp Med (1985) 1.60
Intra-anal collagen injection for the treatment of faecal incontinence. Br J Surg (2006) 1.58
Molecular characterization of vanB elements in naturally occurring gut anaerobes. Antimicrob Agents Chemother (2005) 1.58
Management of suspected viral encephalitis in children - Association of British Neurologists and British Paediatric Allergy, Immunology and Infection Group national guidelines. J Infect (2011) 1.57
ADP-ribosyltransferase activity of pertussis toxin and immunomodulation by Bordetella pertussis. Science (1988) 1.57
In vitro proliferative responses and antibody titers specific to human acetylcholine receptor synthetic peptides in patients with myasthenia gravis and relation to HLA class II genes. J Clin Invest (1988) 1.57
Isolation of viruses from mosquitoes (Diptera: Culicidae) collected in the Amazon Basin region of Peru. J Med Entomol (2005) 1.57