Published in Proc Natl Acad Sci U S A on March 10, 2014
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Structure of the p300 catalytic core and implications for chromatin targeting and HAT regulation. Nat Struct Mol Biol (2013) 1.33
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Kinetic and mass spectrometric analysis of p300 histone acetyltransferase domain autoacetylation. J Biol Chem (2006) 1.26
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Structure of the histone chaperone CIA/ASF1-double bromodomain complex linking histone modifications and site-specific histone eviction. Proc Natl Acad Sci U S A (2010) 0.95
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Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2. Nature (2006) 7.52
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Structural basis for the histone chaperone activity of Asf1. Cell (2006) 4.95
CBP/p300-mediated acetylation of histone H3 on lysine 56. Nature (2009) 4.83
Drosophila OBP LUSH is required for activity of pheromone-sensitive neurons. Neuron (2005) 4.45
RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination. Nature (2007) 4.35
Acetylated lysine 56 on histone H3 drives chromatin assembly after repair and signals for the completion of repair. Cell (2008) 4.14
Chromatin disassembly mediated by the histone chaperone Asf1 is essential for transcriptional activation of the yeast PHO5 and PHO8 genes. Mol Cell (2004) 3.64
Structural insights into histone demethylation by JMJD2 family members. Cell (2006) 3.37
Proteome-wide analysis in Saccharomyces cerevisiae identifies several PHD fingers as novel direct and selective binding modules of histone H3 methylated at either lysine 4 or lysine 36. J Biol Chem (2006) 3.14
Elevated histone expression promotes life span extension. Mol Cell (2010) 3.09
Chaperoning histones during DNA replication and repair. Cell (2010) 2.99
Transcriptional activators are dispensable for transcription in the absence of Spt6-mediated chromatin reassembly of promoter regions. Mol Cell (2006) 2.98
Perceiving the epigenetic landscape through histone readers. Nat Struct Mol Biol (2012) 2.76
Acetylation in the globular core of histone H3 on lysine-56 promotes chromatin disassembly during transcriptional activation. Proc Natl Acad Sci U S A (2008) 2.44
Nasal chemosensory cells use bitter taste signaling to detect irritants and bacterial signals. Proc Natl Acad Sci U S A (2010) 2.24
Localized histone acetylation and deacetylation triggered by the homologous recombination pathway of double-strand DNA repair. Mol Cell Biol (2005) 2.23
Specific inhibition of p300-HAT alters global gene expression and represses HIV replication. Chem Biol (2007) 2.15
ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation. Mol Cell (2009) 1.95
Activation of the DNA damage checkpoint in yeast lacking the histone chaperone anti-silencing function 1. Mol Cell Biol (2004) 1.94
Structural basis and specificity of acyl-homoserine lactone signal production in bacterial quorum sensing. Mol Cell (2002) 1.92
The histone shuffle: histone chaperones in an energetic dance. Trends Biochem Sci (2010) 1.89
The DIX domain targets dishevelled to actin stress fibres and vesicular membranes. Nature (2002) 1.89
Nucleosome loss leads to global transcriptional up-regulation and genomic instability during yeast aging. Genes Dev (2014) 1.81
Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster. Nat Struct Biol (2003) 1.71
ASF1 binds to a heterodimer of histones H3 and H4: a two-step mechanism for the assembly of the H3-H4 heterotetramer on DNA. Biochemistry (2005) 1.70
Handpicking epigenetic marks with PHD fingers. Nucleic Acids Res (2011) 1.69
Transcriptional regulation by chromatin disassembly and reassembly. Curr Opin Genet Dev (2007) 1.68
The histone chaperone Asf1p mediates global chromatin disassembly in vivo. J Biol Chem (2004) 1.61
Binding of the CHD4 PHD2 finger to histone H3 is modulated by covalent modifications. Biochem J (2009) 1.59
HBO1 HAT complexes target chromatin throughout gene coding regions via multiple PHD finger interactions with histone H3 tail. Mol Cell (2009) 1.58
Specificity of acyl-homoserine lactone synthases examined by mass spectrometry. J Bacteriol (2006) 1.57
Plant homeodomain (PHD) fingers of CHD4 are histone H3-binding modules with preference for unmodified H3K4 and methylated H3K9. J Biol Chem (2011) 1.55
The yeast histone chaperone chromatin assembly factor 1 protects against double-strand DNA-damaging agents. Genetics (2005) 1.48
Targeting of the FYVE domain to endosomal membranes is regulated by a histidine switch. Proc Natl Acad Sci U S A (2005) 1.47
DNA binding and bending by HMG boxes: energetic determinants of specificity. J Mol Biol (2004) 1.46
Chromatin disassembly from the PHO5 promoter is essential for the recruitment of the general transcription machinery and coactivators. Mol Cell Biol (2007) 1.44
X-ray studies of crystalline complexes involving amino acids and peptides. XLIII. Adipic acid complexes of L- and DL-lysine. Acta Crystallogr C (2006) 1.43
The histone chaperone anti-silencing function 1 stimulates the acetylation of newly synthesized histone H3 in S-phase. J Biol Chem (2006) 1.42
Structure of the Pseudomonas aeruginosa acyl-homoserinelactone synthase LasI. Mol Microbiol (2004) 1.40
Combinatorial profiling of chromatin binding modules reveals multisite discrimination. Nat Chem Biol (2010) 1.39
X-ray studies of crystalline complexes involving amino acids and peptides. XLIV. Invariant features of supramolecular association and chiral effects in the complexes of arginine and lysine with tartaric acid. Acta Crystallogr B (2007) 1.38
Bivalent recognition of nucleosomes by the tandem PHD fingers of the CHD4 ATPase is required for CHD4-mediated repression. Proc Natl Acad Sci U S A (2012) 1.37
Quorum-sensing control of antibiotic synthesis in Burkholderia thailandensis. J Bacteriol (2009) 1.33
Mutational analysis of Burkholderia thailandensis quorum sensing and self-aggregation. J Bacteriol (2009) 1.28
The crystal structure of the ING5 PHD finger in complex with an H3K4me3 histone peptide. Proteins (2008) 1.27
Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1. Nat Struct Mol Biol (2012) 1.27
The histone chaperone anti-silencing function 1 is a global regulator of transcription independent of passage through S phase. Mol Cell Biol (2005) 1.27
Structure of the progesterone receptor-deoxyribonucleic acid complex: novel interactions required for binding to half-site response elements. Mol Endocrinol (2006) 1.26
Structural plasticity and enzyme action: crystal structures of mycobacterium tuberculosis peptidyl-tRNA hydrolase. J Mol Biol (2007) 1.24
Natural products: promising resources for cancer drug discovery. Anticancer Agents Med Chem (2012) 1.23
The histone chaperone ASF1 localizes to active DNA replication forks to mediate efficient DNA replication. FASEB J (2006) 1.22
Molecular basis of phosphatidylinositol 4-phosphate and ARF1 GTPase recognition by the FAPP1 pleckstrin homology (PH) domain. J Biol Chem (2011) 1.21
Structural analysis and DNA binding of the HMG domains of the human mitochondrial transcription factor A. Nucleic Acids Res (2009) 1.21
PHD fingers: epigenetic effectors and potential drug targets. Mol Interv (2009) 1.21
A novel mechanism of ligand binding and release in the odorant binding protein 20 from the malaria mosquito Anopheles gambiae. Protein Sci (2012) 1.20
The activity of the histone chaperone yeast Asf1 in the assembly and disassembly of histone H3/H4-DNA complexes. Nucleic Acids Res (2011) 1.19
The NuRD architecture. Cell Mol Life Sci (2013) 1.18
A complex LuxR-LuxI type quorum sensing network in a roseobacterial marine sponge symbiont activates flagellar motility and inhibits biofilm formation. Mol Microbiol (2012) 1.17
Binding of the MLL PHD3 finger to histone H3K4me3 is required for MLL-dependent gene transcription. J Mol Biol (2010) 1.16
Molecular basis for chromatin binding and regulation of MLL5. Proc Natl Acad Sci U S A (2013) 1.15
The role of multiple hydrogen-bonding groups in specific alcohol binding sites in proteins: insights from structural studies of LUSH. J Mol Biol (2008) 1.15
Transcriptional activation by mitochondrial transcription factor A involves preferential distortion of promoter DNA. Nucleic Acids Res (2011) 1.15
FACT and the proteasome promote promoter chromatin disassembly and transcriptional initiation. J Biol Chem (2009) 1.15
The MBT repeats of L3MBTL1 link SET8-mediated p53 methylation at lysine 382 to target gene repression. J Biol Chem (2010) 1.13
DNA binding of a non-sequence-specific HMG-D protein is entropy driven with a substantial non-electrostatic contribution. J Mol Biol (2003) 1.13
Molecular mechanism of membrane docking by the Vam7p PX domain. J Biol Chem (2006) 1.12
Crystal structure of QscR, a Pseudomonas aeruginosa quorum sensing signal receptor. Proc Natl Acad Sci U S A (2011) 1.12
Structural insight into histone recognition by the ING PHD fingers. Curr Drug Targets (2009) 1.11
pH-dependent binding of the Epsin ENTH domain and the AP180 ANTH domain to PI(4,5)P2-containing bilayers. J Mol Biol (2007) 1.11
Functional conservation and specialization among eukaryotic anti-silencing function 1 histone chaperones. Eukaryot Cell (2005) 1.10
Molecular mechanism of membrane targeting by the GRP1 PH domain. J Lipid Res (2008) 1.09
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The role of intercalating residues in chromosomal high-mobility-group protein DNA binding, bending and specificity. Nucleic Acids Res (2003) 1.07
Dominant mutants of the Saccharomyces cerevisiae ASF1 histone chaperone bypass the need for CAF-1 in transcriptional silencing by altering histone and Sir protein recruitment. Genetics (2006) 1.07
The Burkholderia mallei BmaR3-BmaI3 quorum-sensing system produces and responds to N-3-hydroxy-octanoyl homoserine lactone. J Bacteriol (2008) 1.06
The high mobility group box: the ultimate utility player of a cell. Trends Biochem Sci (2012) 1.05
CAF-1-induced oligomerization of histones H3/H4 and mutually exclusive interactions with Asf1 guide H3/H4 transitions among histone chaperones and DNA. Nucleic Acids Res (2012) 1.05
Chemical synthesis and molecular recognition of phosphatase-resistant analogues of phosphatidylinositol-3-phosphate. J Am Chem Soc (2006) 1.05
Prevalence and risk factors of asthma and wheeze in school-going children in Lucknow, North India. Indian Pediatr (2004) 1.05
Biophysical and computational studies of membrane penetration by the GRP1 pleckstrin homology domain. Structure (2011) 1.05
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Tandem PHD fingers of MORF/MOZ acetyltransferases display selectivity for acetylated histone H3 and are required for the association with chromatin. J Mol Biol (2012) 1.05
Effect of n-alcohols on the structure and stability of the Drosophila odorant binding protein LUSH. Biochemistry (2006) 1.04
Conserved molecular interactions within the HBO1 acetyltransferase complexes regulate cell proliferation. Mol Cell Biol (2011) 1.03
Structural insight into p53 recognition by the 53BP1 tandem Tudor domain. J Mol Biol (2010) 1.03
Global replication-independent histone H4 exchange in budding yeast. Eukaryot Cell (2006) 1.02
Differential recognition of phosphorylated transactivation domains of p53 by different p300 domains. J Mol Biol (2007) 1.01
Membrane insertion of the FYVE domain is modulated by pH. Proteins (2009) 1.01
N-(3-hydroxyhexanoyl)-l-homoserine lactone is the biologically relevant quormone that regulates the phz operon of Pseudomonas chlororaphis strain 30-84. Appl Environ Microbiol (2007) 0.98
Epigenetic inheritance of an inducibly nucleosome-depleted promoter and its associated transcriptional state in the apparent absence of transcriptional activators. Epigenetics Chromatin (2009) 0.97
Kinetics of transcription initiation at lacP1. Multiple roles of cyclic AMP receptor protein. J Biol Chem (2003) 0.97
Multivalent recognition of histone tails by the PHD fingers of CHD5. Biochemistry (2012) 0.97