Published in Mol Cell Biol on December 05, 2011
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Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity. Genes Dev (2013) 1.08
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The novel function of JADE1S in cytokinesis of epithelial cells. Cell Cycle (2015) 0.88
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Histone acetyl transferase (HAT) HBO1 and JADE1 in epithelial cell regeneration. Am J Pathol (2012) 0.87
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BRPF3-HBO1 regulates replication origin activation and histone H3K14 acetylation. EMBO J (2015) 0.85
Human T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1. Oncotarget (2016) 0.78
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The Chromatin Regulator BRPF3 Preferentially Activates the HBO1 Acetyltransferase but Is Dispensable for Mouse Development and Survival. J Biol Chem (2015) 0.76
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PFP1, a gene encoding an Epc-N domain-containing protein, is essential for pathogenicity of the barley pathogen Rhynchosporium commune. Eukaryot Cell (2014) 0.75
Myst2/Kat7 histone acetyltransferase interaction proteomics reveals tumour-suppressor Niam as a novel binding partner in embryonic stem cells. Sci Rep (2017) 0.75
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WAF1, a potential mediator of p53 tumor suppression. Cell (1993) 38.72
Mapping and analysis of chromatin state dynamics in nine human cell types. Nature (2011) 24.37
Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science (2009) 20.49
Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell (2007) 17.98
How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers. Nat Struct Mol Biol (2007) 10.98
A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling. Nature (2006) 10.73
GammaH2AX and cancer. Nat Rev Cancer (2008) 9.77
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Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. Nat Cell Biol (2009) 7.74
Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF. Nature (2006) 7.70
Chemokine signaling via the CXCR2 receptor reinforces senescence. Cell (2008) 7.65
Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2. Nature (2006) 7.52
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Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4. Cell (2007) 6.62
Model-based variance-stabilizing transformation for Illumina microarray data. Nucleic Acids Res (2008) 6.15
ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. Mol Cell (2006) 5.01
Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression. Nature (2007) 4.49
RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination. Nature (2007) 4.35
Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans. Mol Cell Biol (2004) 4.31
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Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs. Mol Cell (2006) 3.87
Combined action of PHD and chromo domains directs the Rpd3S HDAC to transcribed chromatin. Science (2007) 3.69
A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement. Immunity (2007) 3.54
Molecular target class is predictive of in vitro response profile. Cancer Res (2010) 3.27
Cross-regulation of histone modifications. Nat Struct Mol Biol (2007) 3.09
A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16. Mol Cell Biol (2005) 3.04
Mechanisms involved in the regulation of histone lysine demethylases. Curr Opin Cell Biol (2008) 2.81
Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response. Nature (2007) 2.54
The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2. Proc Natl Acad Sci U S A (2007) 2.53
Examination of the expanding pathways for the regulation of p21 expression and activity. Cell Signal (2010) 2.44
p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity. Cancer Res (2003) 2.40
Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL. Nat Cell Biol (2008) 2.34
Yeast enhancer of polycomb defines global Esa1-dependent acetylation of chromatin. Genes Dev (2003) 2.30
The Yng1p plant homeodomain finger is a methyl-histone binding module that recognizes lysine 4-methylated histone H3. Mol Cell Biol (2006) 2.29
After a decade of study-ING, a PHD for a versatile family of proteins. Trends Biochem Sci (2007) 2.00
DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53. Proc Natl Acad Sci U S A (2001) 2.00
ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation. Mol Cell (2009) 1.95
HBO1 histone acetylase activity is essential for DNA replication licensing and inhibited by Geminin. Mol Cell (2010) 1.95
Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes. Mol Cell Biol (2008) 1.89
The MYST family of histone acetyltransferases and their intimate links to cancer. Oncogene (2007) 1.69
HBO1 histone acetylase is a coactivator of the replication licensing factor Cdt1. Genes Dev (2008) 1.67
MOZ and MORF, two large MYSTic HATs in normal and cancer stem cells. Oncogene (2007) 1.63
HBO1 HAT complexes target chromatin throughout gene coding regions via multiple PHD finger interactions with histone H3 tail. Mol Cell (2009) 1.58
The Saccharomyces cerevisiae Piccolo NuA4 histone acetyltransferase complex requires the Enhancer of Polycomb A domain and chromodomain to acetylate nucleosomes. Mol Cell Biol (2005) 1.52
Alterations in gene expression induced by the lipid peroxidation product, 4-hydroxy-2-nonenal. Chem Res Toxicol (2005) 1.47
Regulation of NuA4 histone acetyltransferase activity in transcription and DNA repair by phosphorylation of histone H4. Mol Cell Biol (2005) 1.46
A novel PHD-finger motif protein, p47ING3, modulates p53-mediated transcription, cell cycle control, and apoptosis. Oncogene (2003) 1.40
Grow-ING, Age-ING and Die-ING: ING proteins link cancer, senescence and apoptosis. Exp Cell Res (2006) 1.40
The new tumor suppressor genes ING: genomic structure and status in cancer. Int J Cancer (2008) 1.30
Moz and retinoic acid coordinately regulate H3K9 acetylation, Hox gene expression, and segment identity. Dev Cell (2009) 1.28
The crystal structure of the ING5 PHD finger in complex with an H3K4me3 histone peptide. Proteins (2008) 1.27
The von Hippel-Lindau tumor suppressor stabilizes novel plant homeodomain protein Jade-1. J Biol Chem (2002) 1.26
The enhancer of polycomb gene of Drosophila encodes a chromatin protein conserved in yeast and mammals. Development (1998) 1.26
MYST family histone acetyltransferases take center stage in stem cells and development. Bioessays (2009) 1.24
von Hippel-Lindau partner Jade-1 is a transcriptional co-activator associated with histone acetyltransferase activity. J Biol Chem (2004) 1.18
Jade-1, a candidate renal tumor suppressor that promotes apoptosis. Proc Natl Acad Sci U S A (2005) 1.17
Yng1p modulates the activity of Sas3p as a component of the yeast NuA3 Hhistone acetyltransferase complex. Mol Cell Biol (2002) 1.15
The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis. Blood (2011) 1.14
Tumor suppressor von Hippel-Lindau (VHL) stabilization of Jade-1 protein occurs through plant homeodomains and is VHL mutation dependent. Cancer Res (2004) 1.13
Role of Jade-1 in the histone acetyltransferase (HAT) HBO1 complex. J Biol Chem (2008) 1.09
HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development. Mol Cell Biol (2010) 1.01
CPEB control of NF-kappaB nuclear localization and interleukin-6 production mediates cellular senescence. Mol Cell Biol (2011) 0.98
The Epc-N domain: a predicted protein-protein interaction domain found in select chromatin associated proteins. BMC Genomics (2006) 0.98
Monocytic leukemia zinc finger (MOZ) interacts with p53 to induce p21 expression and cell-cycle arrest. J Biol Chem (2008) 0.98
p8/nupr1 regulates DNA-repair activity after double-strand gamma irradiation-induced DNA damage. J Cell Physiol (2009) 0.92
(de)MYSTification and INGenuity of tumor suppressors. Cell Mol Life Sci (2008) 0.80
Inhibitor of growth tumor suppressors in cancer progression. Cell Mol Life Sci (2010) 0.80
Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. Mol Cell (2006) 11.38
ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression. Nature (2006) 9.30
Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2. Nature (2006) 7.52
Mechanisms of resistance to crizotinib in patients with ALK gene rearranged non-small cell lung cancer. Clin Cancer Res (2012) 6.23
ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. Mol Cell (2006) 5.01
In vivo genome editing restores haemostasis in a mouse model of haemophilia. Nature (2011) 4.81
Precise genome modification in the crop species Zea mays using zinc-finger nucleases. Nature (2009) 4.71
RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination. Nature (2007) 4.35
Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans. Mol Cell Biol (2004) 4.31
Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites. Mol Cell (2004) 4.17
HDAC6 modulates cell motility by altering the acetylation level of cortactin. Mol Cell (2007) 3.99
Structural insights into histone demethylation by JMJD2 family members. Cell (2006) 3.37
The diverse functions of histone acetyltransferase complexes. Trends Genet (2003) 3.35
Proteome-wide analysis in Saccharomyces cerevisiae identifies several PHD fingers as novel direct and selective binding modules of histone H3 methylated at either lysine 4 or lysine 36. J Biol Chem (2006) 3.14
A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16. Mol Cell Biol (2005) 3.04
The highly conserved and multifunctional NuA4 HAT complex. Curr Opin Genet Dev (2004) 3.03
Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells. Nat Cell Biol (2011) 2.79
Perceiving the epigenetic landscape through histone readers. Nat Struct Mol Biol (2012) 2.76
Cellular machineries for chromosomal DNA repair. Genes Dev (2004) 2.66
Role for miR-204 in human pulmonary arterial hypertension. J Exp Med (2011) 2.60
Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9. Mol Cell Biol (2005) 2.48
Hypoxia-inducible factor 1: regulation by hypoxic and non-hypoxic activators. Int J Biochem Cell Biol (2005) 2.43
Targeted transgene integration in plant cells using designed zinc finger nucleases. Plant Mol Biol (2008) 2.40
Yeast enhancer of polycomb defines global Esa1-dependent acetylation of chromatin. Genes Dev (2003) 2.30
The histone variant macroH2A interferes with transcription factor binding and SWI/SNF nucleosome remodeling. Mol Cell (2003) 2.29
Hypoxic gene activation by lipopolysaccharide in macrophages: implication of hypoxia-inducible factor 1alpha. Blood (2003) 2.28
Association with class IIa histone deacetylases upregulates the sumoylation of MEF2 transcription factors. Mol Cell Biol (2005) 2.18
Interplay of chromatin modifiers on a short basic patch of histone H4 tail defines the boundary of telomeric heterochromatin. Mol Cell (2007) 2.07
MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair. Mol Cell Biol (2010) 2.03
Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme. Genome Res (2012) 2.02
Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2. Mol Cell Biol (2006) 2.01
Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms. Mol Cell (2003) 1.95
ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation. Mol Cell (2009) 1.95
Induction of hypoxia-inducible factor-1alpha by transcriptional and translational mechanisms. J Biol Chem (2002) 1.90
Efficient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-finger nucleases. Proc Natl Acad Sci U S A (2011) 1.90
Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes. Mol Cell Biol (2008) 1.89
The DIX domain targets dishevelled to actin stress fibres and vesicular membranes. Nature (2002) 1.89
YAP, TAZ, and Yorkie: a conserved family of signal-responsive transcriptional coregulators in animal development and human disease. Biochem Cell Biol (2009) 1.81
The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres. Mol Cell Biol (2004) 1.80
Transforming growth factor beta1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression. J Biol Chem (2006) 1.73
Handpicking epigenetic marks with PHD fingers. Nucleic Acids Res (2011) 1.69
Binding of the CHD4 PHD2 finger to histone H3 is modulated by covalent modifications. Biochem J (2009) 1.59
HBO1 HAT complexes target chromatin throughout gene coding regions via multiple PHD finger interactions with histone H3 tail. Mol Cell (2009) 1.58
Control of MEF2 transcriptional activity by coordinated phosphorylation and sumoylation. J Biol Chem (2005) 1.58
Histone chaperones: modulators of chromatin marks. Mol Cell (2011) 1.56
Plant homeodomain (PHD) fingers of CHD4 are histone H3-binding modules with preference for unmodified H3K4 and methylated H3K9. J Biol Chem (2011) 1.55
The Saccharomyces cerevisiae Piccolo NuA4 histone acetyltransferase complex requires the Enhancer of Polycomb A domain and chromodomain to acetylate nucleosomes. Mol Cell Biol (2005) 1.52
Role of the tetradecapeptide repeat domain of human histone deacetylase 6 in cytoplasmic retention. J Biol Chem (2004) 1.47
Targeting of the FYVE domain to endosomal membranes is regulated by a histidine switch. Proc Natl Acad Sci U S A (2005) 1.47
Recruitment of the NuA4 complex poises the PHO5 promoter for chromatin remodeling and activation. EMBO J (2004) 1.46
Regulation of NuA4 histone acetyltransferase activity in transcription and DNA repair by phosphorylation of histone H4. Mol Cell Biol (2005) 1.46
Cancer translocations in human cells induced by zinc finger and TALE nucleases. Genome Res (2013) 1.44
A histone deacetylase 4/myogenin positive feedback loop coordinates denervation-dependent gene induction and suppression. Mol Biol Cell (2008) 1.44
Hypoxia-inducible factor-1alpha stabilization in nonhypoxic conditions: role of oxidation and intracellular ascorbate depletion. Mol Biol Cell (2007) 1.41
Comprehensive lysine acetylomes emerging from bacteria to humans. Trends Biochem Sci (2010) 1.40
Functional characterization of an amino-terminal region of HDAC4 that possesses MEF2 binding and transcriptional repressive activity. J Biol Chem (2003) 1.40
Eaf1 is the platform for NuA4 molecular assembly that evolutionarily links chromatin acetylation to ATP-dependent exchange of histone H2A variants. Mol Cell Biol (2008) 1.39
Combinatorial profiling of chromatin binding modules reveals multisite discrimination. Nat Chem Biol (2010) 1.39
Mutations in KAT6B, encoding a histone acetyltransferase, cause Genitopatellar syndrome. Am J Hum Genet (2012) 1.39
Arrest-defective-1 protein, an acetyltransferase, does not alter stability of hypoxia-inducible factor (HIF)-1alpha and is not induced by hypoxia or HIF. J Biol Chem (2005) 1.38
Bivalent recognition of nucleosomes by the tandem PHD fingers of the CHD4 ATPase is required for CHD4-mediated repression. Proc Natl Acad Sci U S A (2012) 1.37
MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2. Oncogene (2002) 1.34
Signal transducers and activators of transcription-3/pim1 axis plays a critical role in the pathogenesis of human pulmonary arterial hypertension. Circulation (2011) 1.33
Identification of HDAC10, a novel class II human histone deacetylase containing a leucine-rich domain. Nucleic Acids Res (2002) 1.33
Yeast G1 DNA damage checkpoint regulation by H2A phosphorylation is independent of chromatin remodeling. Proc Natl Acad Sci U S A (2006) 1.32
NuA4-dependent acetylation of nucleosomal histones H4 and H2A directly stimulates incorporation of H2A.Z by the SWR1 complex. J Biol Chem (2010) 1.32
MYST protein acetyltransferase activity requires active site lysine autoacetylation. EMBO J (2011) 1.29
Caspase-mediated specific cleavage of human histone deacetylase 4. J Biol Chem (2004) 1.29
Connection between histone H2A variants and chromatin remodeling complexes. Biochem Cell Biol (2009) 1.28
Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1. Nat Struct Mol Biol (2012) 1.27
The crystal structure of the ING5 PHD finger in complex with an H3K4me3 histone peptide. Proteins (2008) 1.27
Quantitative proteomics profiling of the poly(ADP-ribose)-related response to genotoxic stress. Nucleic Acids Res (2012) 1.25
Histone modifications in response to DNA damage. Mutat Res (2007) 1.25