Published in FEBS Lett on March 15, 2014
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A molecular signature in the pannexin1 intracellular loop confers channel activation by the α1 adrenoreceptor in smooth muscle cells. Sci Signal (2015) 1.53
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Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway. J Immunol (2011) 1.55
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ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels. J Neurochem (2011) 1.52
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Pannexin 1, an ATP release channel, is activated by caspase cleavage of its pore-associated C-terminal autoinhibitory region. J Biol Chem (2012) 1.44
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From mechanosensitivity to inflammatory responses: new players in the pathology of glaucoma. Curr Eye Res (2013) 1.31
FGF-1 induces ATP release from spinal astrocytes in culture and opens pannexin and connexin hemichannels. Proc Natl Acad Sci U S A (2010) 1.30
The purinergic receptor P2Y2 receptor mediates chemotaxis of dendritic cells and eosinophils in allergic lung inflammation. Allergy (2010) 1.26
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Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection. J Exp Med (2011) 1.22
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Moving through the gate in ATP-activated P2X receptors. Trends Biochem Sci (2012) 1.17
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Genetic ablation of Pannexin1 protects retinal neurons from ischemic injury. PLoS One (2012) 1.10
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New insights regarding the regulation of chemotaxis by nucleotides, adenosine, and their receptors. Purinergic Signal (2012) 1.04
Extracellular ATP and P2 receptors are required for IL-8 to induce neutrophil migration. Cytokine (2009) 1.03
ATP release from dying autophagic cells and their phagocytosis are crucial for inflammasome activation in macrophages. PLoS One (2012) 1.03
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Physiological roles and potential therapeutic applications of the P2X7 receptor in inflammation and pain. Molecules (2013) 1.02
ATP released via pannexin-1 hemichannels mediates bladder overactivity triggered by urothelial P2Y6 receptors. Biochem Pharmacol (2013) 1.01
Transient P2X7 receptor activation triggers macrophage death independent of Toll-like receptors 2 and 4, caspase-1, and pannexin-1 proteins. J Biol Chem (2012) 1.01
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The food dye FD&C Blue No. 1 is a selective inhibitor of the ATP release channel Panx1. J Gen Physiol (2013) 1.01
Pannexin 1 constitutes the large conductance cation channel of cardiac myocytes. J Biol Chem (2010) 1.00
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Pannexin 1 involvement in bladder dysfunction in a multiple sclerosis model. Sci Rep (2013) 0.98
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Purinergic receptors are required for HIV-1 infection of primary human macrophages. J Immunol (2012) 0.96
S-nitrosylation inhibits pannexin 1 channel function. J Biol Chem (2012) 0.96
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Extracellular ATP may contribute to tissue repair by rapidly stimulating purinergic receptor X7-dependent vascular endothelial growth factor release from primary human monocytes. J Immunol (2010) 0.95
The P2X7 receptor and Pannexin-1 are both required for the promotion of multinucleated macrophages by the inflammatory cytokine GM-CSF. J Immunol (2011) 0.94
The bizarre pharmacology of the ATP release channel pannexin1. Neuropharmacology (2013) 0.93
Splice variants of the P2X7 receptor reveal differential agonist dependence and functional coupling with pannexin-1. J Cell Sci (2012) 0.93
Histamine induces ATP release from human subcutaneous fibroblasts, via pannexin-1 hemichannels, leading to Ca2+ mobilization and cell proliferation. J Biol Chem (2013) 0.92
Carbenoxolone blocks endotoxin-induced protein kinase R (PKR) activation and high mobility group box 1 (HMGB1) release. Mol Med (2013) 0.92
Purinergic signaling in inflammatory cells: P2 receptor expression, functional effects, and modulation of inflammatory responses. Purinergic Signal (2013) 0.92
P2X4 assembles with P2X7 and pannexin-1 in gingival epithelial cells and modulates ATP-induced reactive oxygen species production and inflammasome activation. PLoS One (2013) 0.91
Pannexin 1 channels link chemoattractant receptor signaling to local excitation and global inhibition responses at the front and back of polarized neutrophils. J Biol Chem (2013) 0.91
Extracellular ATP reduces HIV-1 transfer from immature dendritic cells to CD4+ T lymphocytes. Retrovirology (2008) 0.87
Extracellular ATP-stimulated macrophages produce macrophage inflammatory protein-2 which is important for neutrophil migration. Immunology (2012) 0.86
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Expression and localization of pannexin-1 hemichannels in human colon in health and disease. Neurogastroenterol Motil (2013) 0.85
The adenosine 2A receptor agonist GW328267C improves lung function after acute lung injury in rats. Am J Physiol Lung Cell Mol Physiol (2012) 0.85
CD39 expression by hepatic myeloid dendritic cells attenuates inflammation in liver transplant ischemia-reperfusion injury in mice. Hepatology (2013) 0.82
Adipocyte P2X7 receptors expression: a role in modulating inflammatory response in subjects with metabolic syndrome? Atherosclerosis (2011) 0.81
Stretch of atrial myocytes stimulates recruitment of macrophages via ATP released through gap-junction channels. J Pharmacol Sci (2012) 0.80
Diverse post-translational modifications of the pannexin family of channel-forming proteins. Channels (Austin) (2014) 0.79
Extracellular ATP and Toll-like receptor 2 agonists trigger in human monocytes an activation program that favors T helper 17. PLoS One (2013) 0.78
Extracellular adenine nucleotides inhibit the release of major monocyte recruiters by human monocyte-derived dendritic cells. FEBS Lett (2006) 0.78