Published in Purinergic Signal on April 12, 2012
Unexpected link between an antibiotic, pannexin channels and apoptosis. Nature (2014) 2.06
Nucleotide signalling during inflammation. Nature (2014) 1.85
Differential release of β-NAD(+) and ATP upon activation of enteric motor neurons in primate and murine colons. Neurogastroenterol Motil (2013) 1.63
Apical targeting of the P2Y(4) receptor is directed by hydrophobic and basic residues in the cytoplasmic tail. Am J Physiol Cell Physiol (2012) 1.42
ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release. Proc Natl Acad Sci U S A (2013) 1.31
P2X7 receptor regulation of non-classical secretion from immune effector cells. Cell Microbiol (2012) 1.28
Purinergic signalling: from discovery to current developments. Exp Physiol (2013) 1.08
The purinergic neurotransmitter revisited: a single substance or multiple players? Pharmacol Ther (2014) 1.06
New insights regarding the regulation of chemotaxis by nucleotides, adenosine, and their receptors. Purinergic Signal (2012) 1.04
Differentiating connexin hemichannels and pannexin channels in cellular ATP release. FEBS Lett (2014) 1.01
Discovery of purinergic signalling, the initial resistance and current explosion of interest. Br J Pharmacol (2012) 0.98
Cellular expression profile for interstitial cells of cajal in bladder - a cell often misidentified as myocyte or myofibroblast. PLoS One (2012) 0.98
The Relationship of Mucus Concentration (Hydration) to Mucus Osmotic Pressure and Transport in Chronic Bronchitis. Am J Respir Crit Care Med (2015) 0.97
Introduction and perspective, historical note. Front Cell Neurosci (2013) 0.93
TRPA1 and TRPV4 activation in human odontoblasts stimulates ATP release. J Dent Res (2014) 0.92
Vesicular expression and release of ATP from dopaminergic neurons of the mouse retina and midbrain. Front Cell Neurosci (2015) 0.91
The role of pannexin1 in the induction and resolution of inflammation. FEBS Lett (2014) 0.91
A novel mechanism of B cell-mediated immune suppression through CD73 expression and adenosine production. J Immunol (2014) 0.90
Chemotherapeutic drugs induce ATP release via caspase-gated pannexin-1 channels and a caspase/pannexin-1-independent mechanism. J Biol Chem (2014) 0.89
Pannexin 1 channels play essential roles in urothelial mechanotransduction and intercellular signaling. PLoS One (2014) 0.86
Purinergic signalling and diabetes. Purinergic Signal (2013) 0.86
Role of vesicular nucleotide transporter VNUT (SLC17A9) in release of ATP from AR42J cells and mouse pancreatic acinar cells. Purinergic Signal (2014) 0.84
Neuronal and extraneuronal release of ATP and NAD(+) in smooth muscle. IUBMB Life (2012) 0.83
Adenosine-A3 receptors in neutrophil microdomains promote the formation of bacteria-tethering cytonemes. EMBO Rep (2013) 0.83
Cellular mechanisms of tissue fibrosis. 6. Purinergic signaling and response in fibroblasts and tissue fibrosis. Am J Physiol Cell Physiol (2013) 0.83
Gpr171, a putative P2Y-like receptor, negatively regulates myeloid differentiation in murine hematopoietic progenitors. Exp Hematol (2012) 0.82
Purinergic and calcium signaling in macrophage function and plasticity. Front Immunol (2014) 0.81
Bile acid effects are mediated by ATP release and purinergic signalling in exocrine pancreatic cells. Cell Commun Signal (2015) 0.80
The properties, functions, and pathophysiology of maxi-anion channels. Pflugers Arch (2016) 0.79
Ecto-nucleoside triphosphate diphosphohydrolase 2 modulates local ATP-induced calcium signaling in human HaCaT keratinocytes. PLoS One (2013) 0.79
P2 receptors in renal autoregulation. Curr Vasc Pharmacol (2014) 0.78
P2Y2 purinergic receptor activation is essential for efficient hepatocyte proliferation in response to partial hepatectomy. Am J Physiol Gastrointest Liver Physiol (2014) 0.78
Purinergic signaling in early inflammatory events of the foreign body response: modulating extracellular ATP as an enabling technology for engineered implants and tissues. Tissue Eng Part B Rev (2014) 0.78
Fibroblast cytoskeletal remodeling induced by tissue stretch involves ATP signaling. J Cell Physiol (2013) 0.77
ATP release, generation and hydrolysis in exocrine pancreatic duct cells. Purinergic Signal (2015) 0.77
Expression of Vesicular Nucleotide Transporter in Rat Odontoblasts. Acta Histochem Cytochem (2016) 0.76
P2X receptors regulate adenosine diphosphate release from hepatic cells. Purinergic Signal (2014) 0.76
Modeling Interactions among Individual P2 Receptors to Explain Complex Response Patterns over a Wide Range of ATP Concentrations. Front Physiol (2016) 0.76
Regulation of bone and cartilage by adenosine signaling. Purinergic Signal (2016) 0.76
Function without form: an ongoing search for maxi-anion channel proteins. Focus on "Maxi-anion channel and pannexin 1 hemichannel constitute separate pathways for swelling-induced ATP release in murine L929 fibrosarcoma cells". Am J Physiol Cell Physiol (2012) 0.76
Extracellular purines, purinergic receptors and tumor growth. Oncogene (2016) 0.76
Regulation of extracellular ATP in human erythrocytes infected with Plasmodium falciparum. PLoS One (2014) 0.76
Use of luciferase probes to measure ATP in living cells and animals. Nat Protoc (2017) 0.75
UDP-glucose promotes neutrophil recruitment in the lung. Purinergic Signal (2016) 0.75
Dynamic Regulation of Cell Volume and Extracellular ATP of Human Erythrocytes. PLoS One (2016) 0.75
Clock Genes Regulate the Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT in an Ex Vivo Mouse Bladder Mucosa. PLoS One (2017) 0.75
Extracellular ATP and other nucleotides-ubiquitous triggers of intercellular messenger release. Purinergic Signal (2015) 0.75
Nucleotides and nucleoside signaling in the regulation of the epithelium to mesenchymal transition (EMT). Purinergic Signal (2016) 0.75
What Else Can CD39 Tell Us? Front Immunol (2017) 0.75
Nucleotide transmitters ATP and ADP mediate intercellular calcium wave communication via P2Y12/13 receptors among BV-2 microglia. PLoS One (2017) 0.75
An autocrine ATP release mechanism regulates basal ciliary activity in airway epithelium. J Physiol (2017) 0.75
Sheath Cell Invasion and Trans-differentiation Repair Mechanical Damage Caused by Loss of Caveolae in the Zebrafish Notochord. Curr Biol (2017) 0.75
Adenosine: Direct and Indirect Actions on Gastric Acid Secretion. Front Physiol (2017) 0.75
Hyperosmotic stress induces ATP release and changes in P2X7 receptor levels in human corneal and conjunctival epithelial cells. Purinergic Signal (2017) 0.75
Purinergic P2Y1 Receptors Control Rapid Expression of Plasma Membrane Processes in Hippocampal Astrocytes. Mol Neurobiol (2016) 0.75
P2Y1R is involved in visceral hypersensitivity in rats with experimental irritable bowel syndrome. World J Gastroenterol (2017) 0.75
Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor. EMBO J (2006) 8.12
TRP channels. Annu Rev Biochem (2007) 8.09
T cell activation. Annu Rev Immunol (2009) 7.40
Astrocytic purinergic signaling coordinates synaptic networks. Science (2005) 6.55
ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors. Science (2006) 6.00
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance. Nature (2009) 4.98
Astrocytes control breathing through pH-dependent release of ATP. Science (2010) 4.88
Pannexin membrane channels are mechanosensitive conduits for ATP. FEBS Lett (2004) 4.73
P2X receptors as cell-surface ATP sensors in health and disease. Nature (2006) 4.55
Connexins regulate calcium signaling by controlling ATP release. Proc Natl Acad Sci U S A (1998) 4.35
Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis. Nature (2010) 4.10
Pannexin 1 in erythrocytes: function without a gap. Proc Natl Acad Sci U S A (2006) 4.03
The role of pannexin 1 hemichannels in ATP release and cell-cell communication in mouse taste buds. Proc Natl Acad Sci U S A (2007) 4.01
Activation of pannexin 1 channels by ATP through P2Y receptors and by cytoplasmic calcium. FEBS Lett (2005) 3.89
Pharmacological properties of homomeric and heteromeric pannexin hemichannels expressed in Xenopus oocytes. J Neurochem (2005) 3.87
The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance. Purinergic Signal (2006) 3.52
Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade. Biochim Biophys Acta (2008) 3.51
Mechanisms of release of nucleotides and integration of their action as P2X- and P2Y-receptor activating molecules. Mol Pharmacol (2003) 3.47
Secretory granule exocytosis. Physiol Rev (2003) 3.32
Volume expansion-sensing outward-rectifier Cl- channel: fresh start to the molecular identity and volume sensor. Am J Physiol (1997) 3.21
Pannexin1 is part of the pore forming unit of the P2X(7) receptor death complex. FEBS Lett (2007) 3.19
P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2+ signaling. J Neurosci (2006) 3.14
Ischemia opens neuronal gap junction hemichannels. Science (2006) 3.00
ATP mediates fast synaptic transmission in mammalian neurons. Nature (1992) 2.87
Pore dilation of neuronal P2X receptor channels. Nat Neurosci (1999) 2.81
Probenecid, a gout remedy, inhibits pannexin 1 channels. Am J Physiol Cell Physiol (2008) 2.79
Pannexin-1 is required for ATP release during apoptosis but not for inflammasome activation. J Immunol (2011) 2.67
Direct association of the gap junction protein connexin-43 with ZO-1 in cardiac myocytes. J Biol Chem (1998) 2.64
Identification of a vesicular nucleotide transporter. Proc Natl Acad Sci U S A (2008) 2.53
Storage and release of ATP from astrocytes in culture. J Biol Chem (2002) 2.50
Pannexin 1: the molecular substrate of astrocyte "hemichannels". J Neurosci (2009) 2.48
The past, present and future of purine nucleotides as signalling molecules. Neuropharmacology (1997) 2.47
Activation of pannexin-1 hemichannels augments aberrant bursting in the hippocampus. Science (2008) 2.46
Connexin 43 hemichannels are permeable to ATP. J Neurosci (2008) 2.46
Amazing chloride channels: an overview. Acta Physiol Scand (2003) 2.42
Pharmacological characterization of pannexin-1 currents expressed in mammalian cells. J Pharmacol Exp Ther (2008) 2.42
Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins. J Cell Sci (2007) 2.41
Regulated ATP release from astrocytes through lysosome exocytosis. Nat Cell Biol (2007) 2.38
Kinetics of cell lysis, dye uptake and permeability changes in cells expressing the rat P2X7 receptor. J Physiol (1999) 2.37
Cell-to-cell spread of calcium signals mediated by ATP receptors in mast cells. Nature (1992) 2.29
Purinergic control of T cell activation by ATP released through pannexin-1 hemichannels. Sci Signal (2008) 2.27
ATP release from activated neutrophils occurs via connexin 43 and modulates adenosine-dependent endothelial cell function. Circ Res (2006) 2.23
Transporters of nucleotide sugars, ATP, and nucleotide sulfate in the endoplasmic reticulum and Golgi apparatus. Annu Rev Biochem (1998) 2.21
Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding. J Clin Invest (2007) 2.19
Emerging roles of presynaptic proteins in Ca++-triggered exocytosis. Science (2002) 2.19
The composition of adrenal chromaffin granules: an assessment of controversial results. Neuroscience (1976) 2.09
Intercellular calcium signaling mediated by point-source burst release of ATP. Proc Natl Acad Sci U S A (2002) 2.08
Pannexin: to gap or not to gap, is that a question? IUBMB Life (2006) 2.05
SNAP-25, a t-SNARE which binds to both syntaxin and synaptobrevin via domains that may form coiled coils. J Biol Chem (1994) 2.04
Physiological regulation of ATP release at the apical surface of human airway epithelia. J Biol Chem (2006) 2.04
Ca2+-dependent synaptotagmin binding to SNAP-25 is essential for Ca2+-triggered exocytosis. Neuron (2002) 2.01
ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca2+ signals across the inner ear. Proc Natl Acad Sci U S A (2008) 2.01
Mechanism of transport and storage of neurotransmitters. CRC Crit Rev Biochem (1987) 1.99
Basal release of ATP: an autocrine-paracrine mechanism for cell regulation. Sci Signal (2010) 1.91
A G protein-coupled receptor for UDP-glucose. J Biol Chem (2000) 1.91
Pannexin 1 contributes to ATP release in airway epithelia. Am J Respir Cell Mol Biol (2009) 1.89
A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP. Am J Physiol Cell Physiol (2008) 1.86
The mechanosensitive nature of TRPV channels. Pflugers Arch (2005) 1.84
Conformational changes in surface structures of isolated connexin 26 gap junctions. EMBO J (2002) 1.84
Purinergic signalling. Br J Pharmacol (2006) 1.83
Pannexin 1 is the conduit for low oxygen tension-induced ATP release from human erythrocytes. Am J Physiol Heart Circ Physiol (2010) 1.81
Connexin hemichannel-mediated CO2-dependent release of ATP in the medulla oblongata contributes to central respiratory chemosensitivity. J Physiol (2010) 1.81
A novel recombinant plasma membrane-targeted luciferase reveals a new pathway for ATP secretion. Mol Biol Cell (2005) 1.80
ATP release from non-excitable cells. Purinergic Signal (2009) 1.78
Failure of the cystic fibrosis transmembrane conductance regulator to conduct ATP. Science (1996) 1.78
Volume-dependent ATP-conductive large-conductance anion channel as a pathway for swelling-induced ATP release. J Gen Physiol (2001) 1.78
Rho signaling regulates pannexin 1-mediated ATP release from airway epithelia. J Biol Chem (2011) 1.76
Exocytotic release of ATP from cultured astrocytes. J Biol Chem (2007) 1.75
Visualization of ATP release in pancreatic acini in response to cholinergic stimulus. Use of fluorescent probes and confocal microscopy. J Biol Chem (2001) 1.74
Organic anion transport is the primary function of the SLC17/type I phosphate transporter family. Pflugers Arch (2003) 1.71
Intracellular calcium changes trigger connexin 32 hemichannel opening. EMBO J (2005) 1.69
Low-molecular-weight constituents of isolated insulin-secretory granules. Bivalent cations, adenine nucleotides and inorganic phosphate. Biochem J (1983) 1.65
The TRPV4 cation channel mediates stretch-evoked Ca2+ influx and ATP release in primary urothelial cell cultures. J Biol Chem (2009) 1.61
Autocrine regulation of T-cell activation by ATP release and P2X7 receptors. FASEB J (2009) 1.61
Modulation of membrane channel currents by gap junction protein mimetic peptides: size matters. Am J Physiol Cell Physiol (2007) 1.60
Coordinated release of nucleotides and mucin from human airway epithelial Calu-3 cells. J Physiol (2007) 1.59
Is ATP a signaling agent in plants? Plant Physiol (2003) 1.58
Molecular physiology and pathology of the nucleotide sugar transporter family (SLC35). Pflugers Arch (2003) 1.55
Release of cellular UDP-glucose as a potential extracellular signaling molecule. Mol Pharmacol (2003) 1.53
Cystic fibrosis transmembrane regulator-independent release of ATP. Its implications for the regulation of P2Y2 receptors in airway epithelia. J Biol Chem (1998) 1.53
Dual role of the TRPV4 channel as a sensor of flow and osmolality in renal epithelial cells. Am J Physiol Renal Physiol (2007) 1.50
Pannexins, distant relatives of the connexin family with specific cellular functions? Bioessays (2009) 1.50
Pathophysiology and puzzles of the volume-sensitive outwardly rectifying anion channel. J Physiol (2009) 1.50
Voltage-dependent anion channel-1 (VDAC-1) contributes to ATP release and cell volume regulation in murine cells. J Gen Physiol (2004) 1.49
Cell swelling-induced ATP release is tightly dependent on intracellular calcium elevations. J Physiol (2004) 1.49
Connexins, pannexins, innexins: novel roles of "hemi-channels". Pflugers Arch (2008) 1.45
ATP release via anion channels. Purinergic Signal (2005) 1.43
Impact of ectoenzymes on p2 and p1 receptor signaling. Adv Pharmacol (2011) 1.43
Vasoconstriction of guinea-pig submucosal arterioles following sympathetic nerve stimulation is mediated by the release of ATP. Br J Pharmacol (1992) 1.43
Volume-regulated anion channels serve as an auto/paracrine nucleotide release pathway in aortic endothelial cells. J Gen Physiol (2002) 1.41
Multiple roles of the vesicular-SNARE TI-VAMP in post-Golgi and endosomal trafficking. FEBS Lett (2009) 1.40
Swelling-induced, CFTR-independent ATP release from a human epithelial cell line: lack of correlation with volume-sensitive cl(-) channels. J Gen Physiol (1999) 1.40
Selective nucleotide-release from dense-core granules in insulin-secreting cells. J Cell Sci (2005) 1.39
Pannexin1 and Pannexin2 channels show quaternary similarities to connexons and different oligomerization numbers from each other. J Biol Chem (2010) 1.39
P2Y6 receptor-Galpha12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis. EMBO J (2008) 1.38
Connexin 30 deficiency impairs renal tubular ATP release and pressure natriuresis. J Am Soc Nephrol (2009) 1.37
Transient receptor potential vanilloid 4 (TRPV4)-dependent calcium influx and ATP release in mouse oesophageal keratinocytes. J Physiol (2011) 1.37
Neutrophils as sources of extracellular nucleotides: functional consequences at the vascular interface. Trends Cardiovasc Med (2008) 1.36
Mechanically induced ATP release from human osteoblastic cells. Biochem Biophys Res Commun (2001) 1.35
The solute carrier (SLC) complement of the human genome: phylogenetic classification reveals four major families. FEBS Lett (2008) 1.34