Published in PLoS One on March 21, 2014
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer. Cell (2015) 2.31
Mechanisms of Hippo pathway regulation. Genes Dev (2016) 1.45
YAP and TAZ: a nexus for Hippo signaling and beyond. Trends Cell Biol (2015) 1.29
Biomechanical and biochemical remodeling of stromal extracellular matrix in cancer. Trends Biotechnol (2015) 0.99
Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit. Cell Rep (2015) 0.97
A YAP/TAZ-miR-130/301 molecular circuit exerts systems-level control of fibrosis in a network of human diseases and physiologic conditions. Sci Rep (2015) 0.83
Cell volume control in three dimensions: Water movement without solute movement. J Gen Physiol (2015) 0.81
Extracellular Matrix Stiffness Regulates Osteogenic Differentiation through MAPK Activation. PLoS One (2015) 0.80
Mechanobiology of YAP and TAZ in physiology and disease. Nat Rev Mol Cell Biol (2017) 0.76
Simulated microgravity inhibits osteogenic differentiation of mesenchymal stem cells via depolymerizing F-actin to impede TAZ nuclear translocation. Sci Rep (2016) 0.75
Concise Review: Stem Cell Microenvironment on a Chip: Current Technologies for Tissue Engineering and Stem Cell Biology. Stem Cells Transl Med (2015) 0.75
Yap/Taz transcriptional activity in endothelial cells promotes intramembranous ossification via the BMP pathway. Sci Rep (2016) 0.75
The role of the extracellular biophysical cues in modulating Hippo-YAP pathway. BMB Rep (2016) 0.75
Stem cell culture and differentiation in microfluidic devices toward organ-on-a-chip. Future Sci OA (2017) 0.75
Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev Cell (2004) 16.89
Role of YAP/TAZ in mechanotransduction. Nature (2011) 11.56
TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. Science (2005) 5.56
TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway. Mol Cell Biol (2008) 5.02
A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator. EMBO J (1999) 4.66
TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins. EMBO J (2000) 4.55
A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells. Cancer Res (2008) 4.33
Mechanotransduction in development: a growing role for contractility. Nat Rev Mol Cell Biol (2009) 4.10
TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal. Nat Cell Biol (2008) 3.44
TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition. J Biol Chem (2009) 3.20
Transduction of mechanical and cytoskeletal cues by YAP and TAZ. Nat Rev Mol Cell Biol (2012) 3.07
From 3D cell culture to organs-on-chips. Trends Cell Biol (2011) 2.83
A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome. Proc Natl Acad Sci U S A (2005) 2.50
The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF{beta}-TrCP E3 ligase. J Biol Chem (2010) 2.27
The transcriptional co-activator TAZ interacts differentially with transcriptional enhancer factor-1 (TEF-1) family members. Biochem J (2005) 2.15
Interstitial flow and its effects in soft tissues. Annu Rev Biomed Eng (2007) 2.12
Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription. EMBO J (2004) 2.12
TAZ interacts with TTF-1 and regulates expression of surfactant protein-C. J Biol Chem (2004) 1.98
TEADs mediate nuclear retention of TAZ to promote oncogenic transformation. J Biol Chem (2009) 1.96
Mechanical strain inhibits adipogenesis in mesenchymal stem cells by stimulating a durable beta-catenin signal. Endocrinology (2008) 1.91
Mechanical loading down-regulates peroxisome proliferator-activated receptor gamma in bone marrow stromal cells and favors osteoblastogenesis at the expense of adipogenesis. Endocrinology (2007) 1.82
Mechanosensitive mechanisms in transcriptional regulation. J Cell Sci (2012) 1.76
Mechanical regulation of signaling pathways in bone. Gene (2012) 1.65
Transcriptional activity of Pax3 is co-activated by TAZ. Biochem Biophys Res Commun (2005) 1.57
Bone tissue engineering: the role of interstitial fluid flow. Biotechnol Bioeng (1994) 1.49
A driving force for change: interstitial flow as a morphoregulator. Trends Cell Biol (2006) 1.43
Mechanical signals as regulators of stem cell fate. Curr Top Dev Biol (2004) 1.35
Modeling interstitial flow in an artery wall allows estimation of wall shear stress on smooth muscle cells. J Biomech Eng (1995) 1.33
Mechanical signal influence on mesenchymal stem cell fate is enhanced by incorporation of refractory periods into the loading regimen. J Biomech (2010) 1.29
Shear stress induces osteogenic differentiation of human mesenchymal stem cells. Regen Med (2010) 1.17
Mechanical activation of β-catenin regulates phenotype in adult murine marrow-derived mesenchymal stem cells. J Orthop Res (2010) 1.12
Interstitial flow through the internal elastic lamina affects shear stress on arterial smooth muscle cells. Am J Physiol Heart Circ Physiol (2000) 1.09
TAZ as a novel enhancer of MyoD-mediated myogenic differentiation. FASEB J (2010) 1.09
Differentiation of neural progenitor cells in a microfluidic chip-generated cytokine gradient. Stem Cells (2009) 1.08
Shear sensitivity of animal cells from a culture-medium perspective. Trends Biotechnol (1998) 1.08
Regulation of tumor invasion by interstitial fluid flow. Phys Biol (2011) 1.01
Mechanical properties of the posterior rotator cuff. Clin Biomech (Bristol, Avon) (2000) 0.98
Gradient generation by an osmotic pump and the behavior of human mesenchymal stem cells under the fetal bovine serum concentration gradient. Lab Chip (2007) 0.93
Regulation of liver cell ganglioside composition by extracellular fluid viscosity. Lipids (1986) 0.93
Effect of fluid shear stress on cardiomyogenic differentiation of rat bone marrow mesenchymal stem cells. Arch Med Res (2010) 0.90
Microplatforms for gradient field generation of various properties and biological applications. J Lab Autom (2014) 0.79
Lab on a chip-based hepatic sinusoidal system simulator for optimal primary hepatocyte culture. Biomed Microdevices (2016) 0.76