Published in Proc Natl Acad Sci U S A on December 06, 2005
The hippo signaling pathway in development and cancer. Dev Cell (2010) 10.54
Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation. Science (2013) 6.43
TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway. Mol Cell Biol (2008) 5.02
The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal. Nat Cell Biol (2011) 4.63
Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation. Arthritis Res Ther (2007) 3.97
β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis. Cell (2012) 3.33
TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition. J Biol Chem (2009) 3.20
The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment. Nat Rev Drug Discov (2013) 3.03
Hippo pathway effector Yap promotes cardiac regeneration. Proc Natl Acad Sci U S A (2013) 2.76
The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma. Genes Dev (2011) 2.48
Hippo pathway-independent restriction of TAZ and YAP by angiomotin. J Biol Chem (2011) 2.47
The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF{beta}-TrCP E3 ligase. J Biol Chem (2010) 2.27
TEADs mediate nuclear retention of TAZ to promote oncogenic transformation. J Biol Chem (2009) 1.96
TAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complex. Mol Cell Biol (2007) 1.86
Physical interaction between TBX5 and MEF2C is required for early heart development. Mol Cell Biol (2009) 1.71
Pax3 and hippo signaling coordinate melanocyte gene expression in neural crest. Cell Rep (2014) 1.46
Molecular antagonism between X-chromosome and autosome signals determines nematode sex. Genes Dev (2013) 1.43
Disease implications of the Hippo/YAP pathway. Trends Mol Med (2015) 1.32
Cardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice. Cell Res (2011) 1.26
TBX22 missense mutations found in patients with X-linked cleft palate affect DNA binding, sumoylation, and transcriptional repression. Am J Hum Genet (2007) 1.23
Glis3 is associated with primary cilia and Wwtr1/TAZ and implicated in polycystic kidney disease. Mol Cell Biol (2009) 1.18
The N-terminal phosphodegron targets TAZ/WWTR1 protein for SCFβ-TrCP-dependent degradation in response to phosphatidylinositol 3-kinase inhibition. J Biol Chem (2012) 1.17
TAZ induces growth factor-independent proliferation through activation of EGFR ligand amphiregulin. Cell Cycle (2012) 1.15
PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ. J Biol Chem (2010) 1.15
Yap1 is required for endothelial to mesenchymal transition of the atrioventricular cushion. J Biol Chem (2014) 1.13
A functional interaction between Hippo-YAP signalling and FoxO1 mediates the oxidative stress response. Nat Commun (2014) 1.12
Signaling and transcriptional networks in heart development and regeneration. Cold Spring Harb Perspect Biol (2013) 1.07
Divergent transcriptional activities determine limb identity. Nat Commun (2010) 1.07
T-box factors determine cardiac design. Cell Mol Life Sci (2007) 1.04
Shox2 mediates Tbx5 activity by regulating Bmp4 in the pacemaker region of the developing heart. Hum Mol Genet (2010) 1.03
Distinct expression and function of alternatively spliced Tbx5 isoforms in cell growth and differentiation. Mol Cell Biol (2008) 1.01
Post-natal cardiomyocytes can generate iPS cells with an enhanced capacity toward cardiomyogenic re-differentation. Cell Death Differ (2012) 0.94
MicroRNA-141 inhibits tumor growth and metastasis in gastric cancer by directly targeting transcriptional co-activator with PDZ-binding motif, TAZ. Cell Death Dis (2015) 0.94
Epigenetic mechanisms in cardiac development and disease. Acta Biochim Biophys Sin (Shanghai) (2012) 0.93
Functional analysis of the novel TBX5 c.1333delC mutation resulting in an extended TBX5 protein. BMC Med Genet (2008) 0.92
The hippo pathway in heart development, regeneration, and diseases. Circ Res (2015) 0.91
Transcriptional co-activator TAZ sustains proliferation and tumorigenicity of neuroblastoma by targeting CTGF and PDGF-β. Oncotarget (2015) 0.90
TM-25659 enhances osteogenic differentiation and suppresses adipogenic differentiation by modulating the transcriptional co-activator TAZ. Br J Pharmacol (2012) 0.88
Shear stress induced by an interstitial level of slow flow increases the osteogenic differentiation of mesenchymal stem cells through TAZ activation. PLoS One (2014) 0.88
Control of Proliferation and Cancer Growth by the Hippo Signaling Pathway. Mol Cancer Res (2015) 0.87
Regulation and function of the TAZ transcription co-activator. Int J Biochem Mol Biol (2011) 0.87
Canonical Wnt signalling activates TAZ through PP1A during osteogenic differentiation. Cell Death Differ (2014) 0.87
Identification of novel Pax8 targets in FRTL-5 thyroid cells by gene silencing and expression microarray analysis. PLoS One (2011) 0.87
Hippo signaling is required for Notch-dependent smooth muscle differentiation of neural crest. Development (2015) 0.86
Screening with a novel cell-based assay for TAZ activators identifies a compound that enhances myogenesis in C2C12 cells and facilitates muscle repair in a muscle injury model. Mol Cell Biol (2014) 0.84
Hippo Signaling Mediators Yap and Taz Are Required in the Epicardium for Coronary Vasculature Development. Cell Rep (2016) 0.84
Cardiac gene activation analysis in mammalian non-myoblasic cells by Nkx2-5, Tbx5, Gata4 and Myocd. PLoS One (2012) 0.83
TAZ promotes epithelial to mesenchymal transition via the upregulation of connective tissue growth factor expression in neuroblastoma cells. Mol Med Rep (2014) 0.83
TAZ suppresses NFAT5 activity through tyrosine phosphorylation. Mol Cell Biol (2012) 0.83
Osteoblast-targeted overexpression of TAZ increases bone mass in vivo. PLoS One (2013) 0.82
Polyomavirus small T antigen interacts with yes-associated protein to regulate cell survival and differentiation. J Virol (2014) 0.81
Prognostic impact of TAZ and β-catenin expression in adenocarcinoma of the esophagogastric junction. Diagn Pathol (2014) 0.81
Intracellular delivery of cell-penetrating peptide-transcriptional factor fusion protein and its role in selective osteogenesis. Int J Nanomedicine (2014) 0.80
Histone deacetylase 3 modulates Tbx5 activity to regulate early cardiogenesis. Hum Mol Genet (2014) 0.80
Genome-wide Analysis Identifies Novel Loci Associated with Ovarian Cancer Outcomes: Findings from the Ovarian Cancer Association Consortium. Clin Cancer Res (2015) 0.79
The Hippo effector TAZ (WWTR1) transforms myoblasts and TAZ abundance is associated with reduced survival in embryonal rhabdomyosarcoma. J Pathol (2016) 0.79
Hippo Component TAZ Functions as a Co-repressor and Negatively Regulates ΔNp63 Transcription through TEA Domain (TEAD) Transcription Factor. J Biol Chem (2015) 0.78
TAZ is highly expressed in gastric signet ring cell carcinoma. Biomed Res Int (2014) 0.77
High expression of TAZ indicates a poor prognosis in retinoblastoma. Diagn Pathol (2015) 0.77
The Hippo transducer TAZ promotes cell proliferation and tumor formation of glioblastoma cells through EGFR pathway. Oncotarget (2016) 0.77
Reconstruction and in vivo analysis of the extinct tbx5 gene from ancient wingless moa (Aves: Dinornithiformes). BMC Evol Biol (2014) 0.77
Human transcriptional coactivator with PDZ-binding motif (TAZ) is downregulated during decidualization. Biol Reprod (2010) 0.77
Interplay between cardiac function and heart development. Biochim Biophys Acta (2016) 0.76
Transformation by Polyomavirus Middle T Antigen Involves a Unique Bimodal Interaction with the Hippo Effector YAP. J Virol (2016) 0.76
The hippo signaling pathway: implications for heart regeneration and disease. Clin Transl Med (2014) 0.76
(-)-Epicatechin gallate (ECG) stimulates osteoblast differentiation via Runt-related transcription factor 2 (RUNX2) and transcriptional coactivator with PDZ-binding motif (TAZ)-mediated transcriptional activation. J Biol Chem (2014) 0.76
Concise Review: Stem Cell Microenvironment on a Chip: Current Technologies for Tissue Engineering and Stem Cell Biology. Stem Cells Transl Med (2015) 0.75
Targeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer Therapy. Genes (Basel) (2016) 0.75
Crystal structure of TAZ-TEAD complex reveals a distinct interaction mode from that of YAP-TEAD complex. Sci Rep (2017) 0.75
WWTR1 (WW domain containing transcription regulator 1). Atlas Genet Cytogenet Oncol Haematol (2014) 0.75
Co-culture with periodontal ligament stem cells enhances osteogenic gene expression in de-differentiated fat cells. Hum Cell (2014) 0.75
A growing role for the Hippo signaling pathway in the heart. J Mol Med (Berl) (2017) 0.75
High expression level of T-box transcription factor 5 predicts unfavorable survival in stage I and II gastric adenocarcinoma. Oncol Lett (2015) 0.75
Disease implication of hyper-Hippo signalling. Open Biol (2016) 0.75
Elucidating the mechanisms of transcription regulation during heart development by next-generation sequencing. J Hum Genet (2015) 0.75
Transcriptional coactivator with PDZ-binding motif is required to sustain testicular function on aging. Aging Cell (2017) 0.75
Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. Nature (2002) 14.37
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. Cell (2005) 10.61
A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60. Science (2001) 7.03
Nonsense-mediated mRNA decay in health and disease. Hum Mol Genet (1999) 6.90
Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. Cell (1998) 6.73
A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease. Cell (2001) 5.77
Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis. Mol Cell (2003) 5.66
TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. Science (2005) 5.56
Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome. Nat Genet (1997) 5.11
Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family. Nat Genet (1997) 4.92
A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator. EMBO J (1999) 4.66
TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins. EMBO J (2000) 4.55
GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors. Proc Natl Acad Sci U S A (1996) 3.82
Differential roles of p300 and PCAF acetyltransferases in muscle differentiation. Mol Cell (1997) 3.54
Atrial natriuretic peptide elevation in congestive heart failure in the human. Science (1986) 3.37
Controlling nuclear receptors: the circular logic of cofactor cycles. Nat Rev Mol Cell Biol (2005) 3.25
Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation. Nat Genet (2001) 3.14
Characterization of a novel protein-binding module--the WW domain. FEBS Lett (1995) 3.11
Biological control through regulated transcriptional coactivators. Cell (2004) 3.05
A genetic link between Tbx1 and fibroblast growth factor signaling. Development (2002) 2.18
Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription. EMBO J (2004) 2.12
The T-box genes Tbx4 and Tbx5 regulate limb outgrowth and identity. Nature (1999) 2.01
TAZ interacts with TTF-1 and regulates expression of surfactant protein-C. J Biol Chem (2004) 1.98
The heartstrings mutation in zebrafish causes heart/fin Tbx5 deficiency syndrome. Development (2002) 1.97
Tbx5 is essential for forelimb bud initiation following patterning of the limb field in the mouse embryo. Development (2003) 1.88
T-box genes in human disorders. Hum Mol Genet (2003) 1.79
T-box genes: what they do and how they do it. Trends Genet (1999) 1.73
Transcriptional coactivation of bone-specific transcription factor Cbfa1 by TAZ. Mol Cell Biol (2003) 1.69
Augmented expression of atrial natriuretic polypeptide gene in ventricle of human failing heart. J Clin Invest (1989) 1.69
Tbx5 is required for forelimb bud formation and continued outgrowth. Development (2003) 1.52
The neuron-restrictive silencer element-neuron-restrictive silencer factor system regulates basal and endothelin 1-inducible atrial natriuretic peptide gene expression in ventricular myocytes. Mol Cell Biol (2001) 1.51
T-box genes and heart development: putting the "T" in heart. Dev Dyn (2005) 1.49
Functional analysis of TBX5 missense mutations associated with Holt-Oram syndrome. J Biol Chem (2002) 1.45
Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome. Hum Mol Genet (2001) 1.29
Expressivity of Holt-Oram syndrome is not predicted by TBX5 genotype. Am J Hum Genet (2003) 1.26
The mutation spectrum in Holt-Oram syndrome. J Med Genet (2000) 1.26
Tbx5 and Tbx4 trigger limb initiation through activation of the Wnt/Fgf signaling cascade. Development (2003) 1.24
Hairy-related transcription factors inhibit GATA-dependent cardiac gene expression through a signal-responsive mechanism. J Biol Chem (2004) 1.24
DiGeorge syndrome: an update. Curr Opin Cardiol (2004) 1.09
Current advances in Holt-Oram syndrome. Curr Opin Pediatr (2002) 1.07
Akt-dependent phosphorylation negatively regulates the transcriptional activity of dHAND by inhibiting the DNA binding activity. Eur J Biochem (2004) 0.85
Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. Nature (2002) 14.37
Control of stress-dependent cardiac growth and gene expression by a microRNA. Science (2007) 12.08
A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure. Proc Natl Acad Sci U S A (2006) 10.09
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc Natl Acad Sci U S A (2008) 9.86
The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat Rev Genet (2009) 9.68
Transient regenerative potential of the neonatal mouse heart. Science (2011) 9.02
NFAT signaling: choreographing the social lives of cells. Cell (2002) 8.17
The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis. Dev Cell (2008) 7.26
Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy. Cell (2002) 7.10
MicroRNAs in stress signaling and human disease. Cell (2012) 6.93
Heart repair by reprogramming non-myocytes with cardiac transcription factors. Nature (2012) 6.65
Deacetylase inhibition promotes the generation and function of regulatory T cells. Nat Med (2007) 6.61
Cardiac plasticity. N Engl J Med (2008) 6.29
Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer. Genesis (2002) 6.11
Pervasive roles of microRNAs in cardiovascular biology. Nature (2011) 6.08
Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis. Cell (2004) 5.80
A twist code determines the onset of osteoblast differentiation. Dev Cell (2004) 5.40
microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart. Genes Dev (2008) 5.39
A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance. Dev Cell (2009) 5.28
MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice. Science (2009) 5.17
The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche. Cell Stem Cell (2010) 5.07
Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore. J Clin Invest (2004) 4.97
MEF2: a calcium-dependent regulator of cell division, differentiation and death. Trends Biochem Sci (2002) 4.96
Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli. Neuron (2007) 4.96
Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression. Nature (2004) 4.76
MicroRNAs: powerful new regulators of heart disease and provocative therapeutic targets. J Clin Invest (2007) 4.76
Signaling pathways in skeletal muscle remodeling. Annu Rev Biochem (2006) 4.75
Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection. Sci Signal (2009) 4.73
MEF2: a central regulator of diverse developmental programs. Development (2007) 4.70
Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth. Development (2003) 4.63
MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury. Genes Dev (2009) 4.62
Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility. Genes Dev (2007) 4.50
Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5. Mol Cell Biol (2004) 4.49
Hypertrophy of the heart: a new therapeutic target? Circulation (2004) 4.45
Myocardin is a master regulator of smooth muscle gene expression. Proc Natl Acad Sci U S A (2003) 4.35
Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development. Mol Cell Biol (2004) 4.24
The myocardin family of transcriptional coactivators: versatile regulators of cell growth, migration, and myogenesis. Genes Dev (2006) 4.18
Concern Calmodulin kinase II and arrhythmias in a mouse model of cardiac hypertrophy. Circulation (2002) 4.16
Myocardin is a key regulator of CArG-dependent transcription of multiple smooth muscle marker genes. Circ Res (2003) 3.99
MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling. Proc Natl Acad Sci U S A (2005) 3.78
Potentiation of serum response factor activity by a family of myocardin-related transcription factors. Proc Natl Acad Sci U S A (2002) 3.74
Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling. J Clin Invest (2006) 3.72
Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21. Cancer Cell (2010) 3.72
MicroRNAs add a new dimension to cardiovascular disease. Circulation (2010) 3.64
An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133. Proc Natl Acad Sci U S A (2007) 3.62
Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo. Nature (2002) 3.60
CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy. J Clin Invest (2006) 3.53
Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity. Cell (2003) 3.40
The serum response factor coactivator myocardin is required for vascular smooth muscle development. Proc Natl Acad Sci U S A (2003) 3.40
Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor. Nat Med (2002) 3.31
Requirement for serum response factor for skeletal muscle growth and maturation revealed by tissue-specific gene deletion in mice. Proc Natl Acad Sci U S A (2005) 3.30
Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo. Proc Natl Acad Sci U S A (2002) 3.27
Control of cardiac growth by histone acetylation/deacetylation. Circ Res (2006) 3.25
Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers. J Clin Invest (2007) 3.19
Toward microRNA-based therapeutics for heart disease: the sense in antisense. Circ Res (2008) 3.18
HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci (2009) 3.18
Reprogramming of human fibroblasts toward a cardiac fate. Proc Natl Acad Sci U S A (2013) 3.14
MicroRNA regulatory networks in cardiovascular development. Dev Cell (2010) 3.09
Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10. Cell (2006) 3.07
Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice. J Clin Invest (2010) 3.04
MicroRNA control of muscle development and disease. Curr Opin Cell Biol (2009) 3.04
MEF2C transcription factor controls chondrocyte hypertrophy and bone development. Dev Cell (2007) 2.96
MicroRNAs flex their muscles. Trends Genet (2008) 2.94
Association of class II histone deacetylases with heterochromatin protein 1: potential role for histone methylation in control of muscle differentiation. Mol Cell Biol (2002) 2.93
Regulation of tendon differentiation by scleraxis distinguishes force-transmitting tendons from muscle-anchoring tendons. Development (2007) 2.92
Control of cardiac development by an evolutionarily conserved transcriptional network. Dev Biol (2002) 2.88
Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways. J Clin Invest (2009) 2.82
Hippo pathway effector Yap promotes cardiac regeneration. Proc Natl Acad Sci U S A (2013) 2.76
TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling. J Clin Invest (2006) 2.74
Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy. Circulation (2006) 2.70
Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family. Proc Natl Acad Sci U S A (2012) 2.66
The delta isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload. Proc Natl Acad Sci U S A (2009) 2.66
MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles. Nat Rev Drug Discov (2012) 2.65
Toward transcriptional therapies for the failing heart: chemical screens to modulate genes. J Clin Invest (2005) 2.65
The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner. Development (2004) 2.61
Modulation of cardiac growth and development by HOP, an unusual homeodomain protein. Cell (2002) 2.53
Therapeutic inhibition of miR-208a improves cardiac function and survival during heart failure. Circulation (2011) 2.52
Unveiling the mechanisms of cell-cell fusion. Science (2005) 2.52
Regulation of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1 alpha ) and mitochondrial function by MEF2 and HDAC5. Proc Natl Acad Sci U S A (2003) 2.48
Regulation of PI3-kinase/Akt signaling by muscle-enriched microRNA-486. Proc Natl Acad Sci U S A (2010) 2.47
AngiomiRs--key regulators of angiogenesis. Curr Opin Genet Dev (2009) 2.40
Regulation of insulin-like growth factor signaling by Yap governs cardiomyocyte proliferation and embryonic heart size. Sci Signal (2011) 2.38
Dose-dependent blockade to cardiomyocyte hypertrophy by histone deacetylase inhibitors. J Biol Chem (2003) 2.35
Delta FosB mediates epigenetic desensitization of the c-fos gene after chronic amphetamine exposure. J Neurosci (2008) 2.34
A threshold of GATA4 and GATA6 expression is required for cardiovascular development. Proc Natl Acad Sci U S A (2006) 2.32
MiR-15 family regulates postnatal mitotic arrest of cardiomyocytes. Circ Res (2011) 2.32
Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice. J Clin Invest (2008) 2.31
Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin. FASEB J (2007) 2.30
Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin. Mol Cell Biol (2005) 2.30
A cardiac microRNA governs systemic energy homeostasis by regulation of MED13. Cell (2012) 2.29
Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis. Nat Genet (2002) 2.27
Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development. Proc Natl Acad Sci U S A (2009) 2.27
The transcriptional coactivator CAMTA2 stimulates cardiac growth by opposing class II histone deacetylases. Cell (2006) 2.26
Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair. Nat Rev Mol Cell Biol (2013) 2.25
Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ. Am J Physiol Renal Physiol (2008) 2.24
The MEF2D transcription factor mediates stress-dependent cardiac remodeling in mice. J Clin Invest (2008) 2.24
A dynamic notch injury response activates epicardium and contributes to fibrosis repair. Circ Res (2010) 2.23
Muscle-specific signaling mechanism that links actin dynamics to serum response factor. Mol Cell Biol (2005) 2.23
Myogenin and class II HDACs control neurogenic muscle atrophy by inducing E3 ubiquitin ligases. Cell (2010) 2.22