Published in Infect Immun on March 24, 2014
Conserved Patterns of Microbial Immune Escape: Pathogenic Microbes of Diverse Origin Target the Human Terminal Complement Inhibitor Vitronectin via a Single Common Motif. PLoS One (2016) 0.81
Hijacking Complement Regulatory Proteins for Bacterial Immune Evasion. Front Microbiol (2016) 0.80
Identification of outer membrane Porin D as a vitronectin-binding factor in cystic fibrosis clinical isolates of Pseudomonas aeruginosa. J Cyst Fibros (2015) 0.77
Moraxella catarrhalis Binds Plasminogen To Evade Host Innate Immunity. Infect Immun (2015) 0.77
Nontypeable Haemophilus influenzae exploits the interaction between protein-E and vitronectin for the adherence and invasion to bronchial epithelial cells. BMC Microbiol (2015) 0.75
The crystal structure of PD1, a Haemophilus surface fibril domain. Acta Crystallogr F Struct Biol Commun (2017) 0.75
Prevalence and distribution of the hmw and hia genes and the HMW and Hia adhesins among genetically diverse strains of nontypeable Haemophilus influenzae. Infect Immun (1998) 1.94
Haemophilus influenzae type b conjugate vaccine use and effectiveness. Lancet Infect Dis (2008) 1.83
Characterization of the genetic locus encoding Haemophilus influenzae type b surface fibrils. J Bacteriol (1996) 1.81
Haemophilus influenzae infections in the H. influenzae type b conjugate vaccine era. J Clin Microbiol (2011) 1.38
Integrin-linked kinase is required for vitronectin-mediated internalization of Streptococcus pneumoniae by host cells. J Cell Sci (2009) 1.35
Vitronectin in bacterial pathogenesis: a host protein used in complement escape and cellular invasion. Mol Microbiol (2010) 1.34
Complement and immune defense: from innate immunity to human diseases. Immunol Lett (2009) 1.30
Architecture and adhesive activity of the Haemophilus influenzae Hsf adhesin. J Bacteriol (2005) 1.22
Human pathogens utilize host extracellular matrix proteins laminin and collagen for adhesion and invasion of the host. FEMS Microbiol Rev (2012) 1.19
Influence of pili, fibrils, and capsule on in vitro adherence by Haemophilus influenzae type b. Mol Microbiol (1996) 1.19
Prevalence and distribution of adhesins in invasive non-type b encapsulated Haemophilus influenzae. Infect Immun (2003) 1.17
Invasive Haemophilus influenzae disease: changing epidemiology and host-parasite interactions in the 21st century. Infect Genet Evol (2009) 1.13
Neisseria meningitidis Opc invasin binds to the sulphated tyrosines of activated vitronectin to attach to and invade human brain endothelial cells. PLoS Pathog (2010) 1.04
Haemophilus influenzae surface fibrils contribute to serum resistance by interacting with vitronectin. J Immunol (2006) 1.04
Haemophilus influenzae and the complement system. Trends Microbiol (2010) 1.03
Progress in vaccination against Haemophilus influenzae type b in the Americas. PLoS Med (2008) 1.02
The choline-binding protein PspC of Streptococcus pneumoniae interacts with the C-terminal heparin-binding domain of vitronectin. J Biol Chem (2013) 1.01
Haemophilus influenzae protein E recognizes the C-terminal domain of vitronectin and modulates the membrane attack complex. Mol Microbiol (2011) 0.98
Haemophilus influenzae acquires vitronectin via the ubiquitous Protein F to subvert host innate immunity. Mol Microbiol (2013) 0.96
The silver anniversary of gold: 25 years of the colloidal gold marker system for immunocytochemistry and histochemistry. Histochem Cell Biol (1996) 0.96
Vitronectin binds to the head region of Moraxella catarrhalis ubiquitous surface protein A2 and confers complement-inhibitory activity. Mol Microbiol (2010) 0.94
Role of alphavbeta5 integrins and vitronectin in Pseudomonas aeruginosa PAK interaction with A549 respiratory cells. Microbes Infect (2004) 0.86
Structure and function of the Haemophilus influenzae autotransporters. Front Cell Infect Microbiol (2011) 0.86
Molecular determinants of the interaction between Haemophilus influenzae and human cells. Am J Respir Crit Care Med (1996) 0.85
The role of complement in the host's defense against Haemophilus influenzae. J Infect Dis (1992) 0.84
Adhesin genes and serum resistance in Haemophilus influenzae type f isolates. J Med Microbiol (2012) 0.82
Haemophilus influenzae type b conjugate vaccines: considerations for vaccination schedules and implications for developing countries. Hum Vaccin (2010) 0.81
Structural basis for the differential binding affinities of the HsfBD1 and HsfBD2 domains in the Haemophilus influenzae Hsf adhesin. J Bacteriol (2009) 0.81
Regulation of kinin B(2) receptors by bradykinin in human lung cells. Biol Chem (2008) 0.79
Lowicryl resins in microbiology. J Struct Biol (1991) 0.79
M protein, a classical bacterial virulence determinant, forms complexes with fibrinogen that induce vascular leakage. Cell (2004) 2.46
Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes. Cell Metab (2012) 2.46
The N terminus of the MUC2 mucin forms trimers that are held together within a trypsin-resistant core fragment. J Biol Chem (2002) 2.44
Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development. Proc Natl Acad Sci U S A (2013) 2.32
Antibody orientation at bacterial surfaces is related to invasive infection. J Exp Med (2012) 2.30
Pathogenic mechanisms in lupus nephritis: Nucleosomes bind aberrant laminin β1 with high affinity and colocalize in the electron-dense deposits. Arthritis Rheumatol (2014) 2.13
Neutrophil extracellular traps that are not degraded in systemic lupus erythematosus activate complement exacerbating the disease. J Immunol (2012) 2.12
C4b-binding protein (C4BP) activates B cells through the CD40 receptor. Immunity (2003) 2.04
Beta2-glycoprotein I can exist in 2 conformations: implications for our understanding of the antiphospholipid syndrome. Blood (2010) 2.04
Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell-stimulating programs in basophils. Nat Immunol (2009) 1.97
Coagulation, an ancestral serine protease cascade, exerts a novel function in early immune defense. Blood (2011) 1.87
Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid Raft-mediated endocytosis negatively regulated by caveolin-1. J Biol Chem (2013) 1.84
β₂-glycoprotein I: a novel component of innate immunity. Blood (2011) 1.75
COMP acts as a catalyst in collagen fibrillogenesis. J Biol Chem (2007) 1.74
Complement evasion strategies of pathogens-acquisition of inhibitors and beyond. Mol Immunol (2009) 1.73
Complexes of matrilin-1 and biglycan or decorin connect collagen VI microfibrils to both collagen II and aggrecan. J Biol Chem (2003) 1.72
The recombinant C-terminus of the human MUC2 mucin forms dimers in Chinese-hamster ovary cells and heterodimers with full-length MUC2 in LS 174T cells. Biochem J (2003) 1.67
Effects of NOD-like receptors in human B lymphocytes and crosstalk between NOD1/NOD2 and Toll-like receptors. J Leukoc Biol (2010) 1.62
The extracellular matrix and inflammation: fibromodulin activates the classical pathway of complement by directly binding C1q. J Biol Chem (2005) 1.61
Genome analysis of Moraxella catarrhalis strain BBH18, [corrected] a human respiratory tract pathogen. J Bacteriol (2010) 1.57
Mutations in components of complement influence the outcome of Factor I-associated atypical hemolytic uremic syndrome. Kidney Int (2009) 1.55
Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells. Proc Natl Acad Sci U S A (2011) 1.52
Activation of the complement system generates antibacterial peptides. Proc Natl Acad Sci U S A (2004) 1.51
Dominant collagen VI mutations are a common cause of Ullrich congenital muscular dystrophy. Hum Mol Genet (2004) 1.51
The factor H variant associated with age-related macular degeneration (His-384) and the non-disease-associated form bind differentially to C-reactive protein, fibromodulin, DNA, and necrotic cells. J Biol Chem (2007) 1.51
Biphasic effect of gingipains from Porphyromonas gingivalis on the human complement system. J Immunol (2007) 1.50
A novel interaction of outer membrane protein A with C4b binding protein mediates serum resistance of Escherichia coli K1. J Immunol (2002) 1.47
Antimicrobial activities of heparin-binding peptides. Eur J Biochem (2004) 1.46
Binding of flavivirus nonstructural protein NS1 to C4b binding protein modulates complement activation. J Immunol (2011) 1.45
Anesthesia aggravates lung damage and precipitates hypotension in endotoxemic sheep. Shock (2010) 1.44
Wnt-5a mRNA translation is suppressed by the Elav-like protein HuR in human breast epithelial cells. Nucleic Acids Res (2006) 1.43
Rheumatoid arthritis and the complement system. Ann Med (2007) 1.42
Activation of the human contact system on neutrophil extracellular traps. J Innate Immun (2009) 1.41
Pathogen entrapment by transglutaminase--a conserved early innate immune mechanism. PLoS Pathog (2010) 1.39
Binding of the complement inhibitor C4bp to serogroup B Neisseria meningitidis. J Immunol (2005) 1.38
Yersinia enterocolitica serum resistance proteins YadA and ail bind the complement regulator C4b-binding protein. PLoS Pathog (2008) 1.36
The contact system--a novel branch of innate immunity generating antibacterial peptides. EMBO J (2006) 1.36
Streptococcal M protein: a multipotent and powerful inducer of inflammation. J Immunol (2006) 1.36
Biglycan organizes collagen VI into hexagonal-like networks resembling tissue structures. J Biol Chem (2002) 1.35
Vitronectin in bacterial pathogenesis: a host protein used in complement escape and cellular invasion. Mol Microbiol (2010) 1.34
The emerging pathogen Moraxella catarrhalis interacts with complement inhibitor C4b binding protein through ubiquitous surface proteins A1 and A2. J Immunol (2004) 1.32
Endoglycosidase treatment abrogates IgG arthritogenicity: importance of IgG glycosylation in arthritis. Eur J Immunol (2007) 1.32
C4b-binding protein and factor H compensate for the loss of membrane-bound complement inhibitors to protect apoptotic cells against excessive complement attack. J Biol Chem (2007) 1.30
A functional variant in the CFI gene confers a high risk of age-related macular degeneration. Nat Genet (2013) 1.29
Streptococcus pyogenes expressing M and M-like surface proteins are phagocytosed but survive inside human neutrophils. Cell Microbiol (2003) 1.29
The Moraxella catarrhalis immunoglobulin D-binding protein MID has conserved sequences and is regulated by a mechanism corresponding to phase variation. J Bacteriol (2003) 1.28
Protein D of Haemophilus influenzae: a protective nontypeable H. influenzae antigen and a carrier for pneumococcal conjugate vaccines. Clin Infect Dis (2008) 1.26
CEACAM1 inhibits Toll-like receptor 2-triggered antibacterial responses of human pulmonary epithelial cells. Nat Immunol (2008) 1.26
Regulation of complement by cartilage oligomeric matrix protein allows for a novel molecular diagnostic principle in rheumatoid arthritis. Arthritis Rheum (2010) 1.23
Suppression of sulfonylurea- and glucose-induced insulin secretion in vitro and in vivo in mice lacking the chloride transport protein ClC-3. Cell Metab (2009) 1.22
Distribution of PG-M/versican variants in human tissues and de novo expression of isoform V3 upon endothelial cell activation, migration, and neoangiogenesis in vitro. J Biol Chem (2002) 1.22
Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation. Mol Immunol (2008) 1.21
The immunoglobulin D-binding protein MID from Moraxella catarrhalis is also an adhesin. Infect Immun (2003) 1.21
Collagen-binding proteoglycan fibromodulin can determine stroma matrix structure and fluid balance in experimental carcinoma. Proc Natl Acad Sci U S A (2007) 1.20
Human C4b-binding protein selectively interacts with Neisseria gonorrhoeae and results in species-specific infection. Proc Natl Acad Sci U S A (2005) 1.20
Human pathogens utilize host extracellular matrix proteins laminin and collagen for adhesion and invasion of the host. FEMS Microbiol Rev (2012) 1.19
Disruption of platelet-derived chemokine heteromers prevents neutrophil extravasation in acute lung injury. Am J Respir Crit Care Med (2012) 1.18
Secretion of heparin-binding protein from human neutrophils is determined by its localization in azurophilic granules and secretory vesicles. Blood (2002) 1.18
Clinical isolates of Streptococcus pneumoniae bind the complement inhibitor C4b-binding protein in a PspC allele-dependent fashion. J Immunol (2009) 1.18
Nontypeable Haemophilus influenzae protein E binds vitronectin and is important for serum resistance. J Immunol (2009) 1.17
Interpain A, a cysteine proteinase from Prevotella intermedia, inhibits complement by degrading complement factor C3. PLoS Pathog (2009) 1.16
Molecular consequences of dominant Bethlem myopathy collagen VI mutations. Ann Neurol (2007) 1.15
Inhibition of coxsackie B virus infection by soluble forms of its receptors: binding affinities, altered particle formation, and competition with cellular receptors. J Virol (2005) 1.15
A mutation in factor I that is associated with atypical hemolytic uremic syndrome does not affect the function of factor I in complement regulation. Mol Immunol (2006) 1.15
Collagen VI glycine mutations: perturbed assembly and a spectrum of clinical severity. Ann Neurol (2008) 1.14
Binding of complement inhibitor C4b-binding protein contributes to serum resistance of Porphyromonas gingivalis. J Immunol (2008) 1.14
Structural basis for interactions between tenascins and lectican C-type lectin domains: evidence for a crosslinking role for tenascins. Structure (2004) 1.14
A novel localization of the G-protein-coupled CysLT1 receptor in the nucleus of colorectal adenocarcinoma cells. Cancer Res (2005) 1.13
Proteolysis of human thrombin generates novel host defense peptides. PLoS Pathog (2010) 1.12
The complement fitness factor H: role in human diseases and for immune escape of pathogens, like pneumococci. Vaccine (2008) 1.12
Antimicrobial activity of histidine-rich peptides is dependent on acidic conditions. Biochim Biophys Acta (2007) 1.12
Scabies mite inactivated serine protease paralogs inhibit the human complement system. J Immunol (2009) 1.11
Domain 5 of high molecular weight kininogen is antibacterial. J Biol Chem (2005) 1.11
Podocytes express ADAMTS13 in normal renal cortex and in patients with thrombotic thrombocytopenic purpura. Br J Haematol (2007) 1.11
Logarithmic phase Escherichia coli K1 efficiently avoids serum killing by promoting C4bp-mediated C3b and C4b degradation. Immunology (2006) 1.10
Vitamin K-dependent protein S localizing complement regulator C4b-binding protein to the surface of apoptotic cells. J Immunol (2002) 1.10
Complement factor I in health and disease. Mol Immunol (2011) 1.10
B cell activation by outer membrane vesicles--a novel virulence mechanism. PLoS Pathog (2010) 1.09
Antimicrobial peptides derived from growth factors. Growth Factors (2007) 1.09
Simvastatin reduces endotoxin-induced acute lung injury by decreasing neutrophil recruitment and radical formation. PLoS One (2012) 1.08
Haemophilus influenzae survival during complement-mediated attacks is promoted by Moraxella catarrhalis outer membrane vesicles. J Infect Dis (2007) 1.08
The leucine-rich repeat protein PRELP binds perlecan and collagens and may function as a basement membrane anchor. J Biol Chem (2002) 1.08
The Kaposi's sarcoma-associated herpesvirus complement control protein (KCP) binds to heparin and cell surfaces via positively charged amino acids in CCP1-2. Mol Immunol (2006) 1.08
beta-Microseminoprotein binds CRISP-3 in human seminal plasma. Biochem Biophys Res Commun (2005) 1.07
A metalloproteinase karilysin present in the majority of Tannerella forsythia isolates inhibits all pathways of the complement system. J Immunol (2012) 1.07