Published in J Exp Med on March 01, 1989
Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase. Antimicrob Agents Chemother (1996) 3.62
Rational modification of a candidate cancer drug for use against Chagas disease. J Med Chem (2009) 1.73
The role of infections in autoimmune disease. Clin Exp Immunol (2009) 1.47
Cloning and expression of Trypanosoma cruzi ribosomal protein P0 and epitope analysis of anti-P0 autoantibodies in Chagas' disease patients. J Exp Med (1992) 1.37
A class of sterol 14-demethylase inhibitors as anti-Trypanosoma cruzi agents. Proc Natl Acad Sci U S A (2003) 1.34
Induction of resistance to azole drugs in Trypanosoma cruzi. Antimicrob Agents Chemother (1998) 1.23
Molecular mimicry between the immunodominant ribosomal protein P0 of Trypanosoma cruzi and a functional epitope on the human beta 1-adrenergic receptor. J Exp Med (1995) 1.23
Chagas' disease and the autoimmunity hypothesis. Clin Microbiol Rev (1999) 1.18
The major 85-kDa surface antigen of the mammalian-stage forms of Trypanosoma cruzi is a family of sialidases. Proc Natl Acad Sci U S A (1991) 1.18
The major 85-kD surface antigen of the mammalian form of Trypanosoma cruzi is encoded by a large heterogeneous family of simultaneously expressed genes. J Exp Med (1990) 1.16
Molecular mimicry by Trypanosoma cruzi: the F1-160 epitope that mimics mammalian nerve can be mapped to a 12-amino acid peptide. Proc Natl Acad Sci U S A (1991) 1.15
Major Trypanosoma cruzi antigenic determinant in Chagas' heart disease shares homology with the systemic lupus erythematosus ribosomal P protein epitope. J Clin Microbiol (1990) 1.11
A trypanosomal protein synergizes with the cytokines ciliary neurotrophic factor and leukemia inhibitory factor to prevent apoptosis of neuronal cells. Mol Biol Cell (2000) 1.10
Influence of acute-phase parasite load on pathology, parasitism, and activation of the immune system at the late chronic phase of Chagas' disease. Infect Immun (1999) 1.08
Detection of live Trypanosoma cruzi in tissues of infected mice by using histochemical stain for beta-galactosidase. Infect Immun (1999) 1.07
FL-160 proteins of Trypanosoma cruzi are expressed from a multigene family and contain two distinct epitopes that mimic nervous tissues. J Exp Med (1993) 1.06
A recombinant protein based on the Trypanosoma cruzi metacyclic trypomastigote 82-kilodalton antigen that induces and effective immune response to acute infection. Infect Immun (1996) 1.04
Recognition of binding sites on Candida albicans by monoclonal antibodies to human leukocyte antigens. Infect Immun (1990) 0.99
Modulation of autoimmunity by treatment of an infectious disease. Infect Immun (2007) 0.98
A cardiac myosin-specific autoimmune response is induced by immunization with Trypanosoma cruzi proteins. Infect Immun (2004) 0.97
Genomic analyses, gene expression and antigenic profile of the trans-sialidase superfamily of Trypanosoma cruzi reveal an undetected level of complexity. PLoS One (2011) 0.94
Regulation of Trypanosoma cruzi-induced myocarditis by programmed death cell receptor 1. Infect Immun (2011) 0.92
Potent anti-Trypanosoma cruzi activities of oxidosqualene cyclase inhibitors. Antimicrob Agents Chemother (2001) 0.90
Expression and cellular localization of molecules of the gp82 family in Trypanosoma cruzi metacyclic trypomastigotes. Infect Immun (2007) 0.85
Further characterization of protective Trypanosoma cruzi-specific CD4+ T-cell clones: T helper type 1-like phenotype and reactivity with shed trypomastigote antigens. Infect Immun (1993) 0.84
Refocusing of B-cell responses following a single amino acid substitution in an antigen. Immunology (2001) 0.83
Binding of the specific ligand to Fc receptors on Trypanosoma cruzi increases the infective capacity of the parasite. Immunology (1991) 0.83
Modulation of cardiocyte functional activity by antibodies against trypanosoma cruzi ribosomal P2 protein C terminus. Infect Immun (2000) 0.83
Biologic and genetics aspects of chagas disease at endemic areas. J Trop Med (2012) 0.81
Chronic experimental Chagas' disease: functional syngeneic T-B-cell cooperation in vitro in the absence of an exogenous stimulus. Infect Immun (1996) 0.81
The SA85-1.1 protein of the Trypanosoma cruzi trans-sialidase superfamily is a dominant T-cell antigen. Infect Immun (2000) 0.79
A Trypanosoma cruzi membrane protein shares an epitope with a lymphocyte activation antigen and induces crossreactive antibodies. J Exp Med (1992) 0.79
Protein geranylgeranyltransferase-I of Trypanosoma cruzi. Mol Biochem Parasitol (2007) 0.78
Antigen Mimicry between Infectious Agents and Self or Environmental Antigens May Lead to Long-Term Regulation of Inflammation. Front Immunol (2013) 0.78
A lytic monoclonal antibody to Trypanosoma cruzi bloodstream trypomastigotes which recognizes an epitope expressed in tissues affected in Chagas' disease. Infect Immun (1994) 0.75
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A (1979) 365.71
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem (1983) 206.01
Efficient isolation of genes by using antibody probes. Proc Natl Acad Sci U S A (1983) 34.00
Surface-specific iodination of membrane proteins of viruses and eucaryotic cells using 1,3,4,6-tetrachloro-3alpha,6alpha-diphenylglycoluril. Biochemistry (1978) 9.04
Molecular mimicry and autoimmune disease. Cell (1987) 5.31
Group A streptococcal antigens cross-reactive with myocardium. Purification of heart-reactive antibody and isolation and characterization of the streptococcal antigen. J Exp Med (1977) 3.80
Chagasic cardiopathy. Demonstration of a serum gamma globulin factor which reacts with endocardium and vascular structures. Circulation (1974) 2.80
Systemic autoimmune disease arises from polyclonal B cell activation. J Exp Med (1987) 2.71
Circulating antibodies to peripheral nerve in American trypanosomiasis (Chagas' disease). Clin Exp Immunol (1979) 1.55
Polyclonal lymphocyte responses to murine Trypanosoma cruzi infection. I. Quantitation of both T- and B-cell responses. Scand J Immunol (1986) 1.46
Antigenic polymorphism of Trypanosoma cruzi: clonal analysis of trypomastigote surface antigens. Eur J Immunol (1984) 1.34
L3T4+ T cells able to mediate parasite-specific delayed-type hypersensitivity play a role in the pathology of experimental Chagas' disease. Eur J Immunol (1987) 1.20
Autoimmune myocarditis induced by Trypanosoma cruzi. Circulation (1985) 1.03
Neuropathy associated with experimental Chagas' disease. Ann Neurol (1985) 0.98
A monoclonal antibody with specificity for Trypanosoma cruzi, central and peripheral neurones and glia. Clin Exp Immunol (1983) 0.97
Autoantibody production is associated with polyclonal B cell activation in autoimmune mice which express the lpr or gld genes. Eur J Immunol (1988) 0.95
Epitopes common to trypanosomes (T. cruzi, T. dionisii and T. vespertilionis (Schizotrypanum)): astrocytes and neurons. J Neuroimmunol (1987) 0.91
Adsorption of Trypanosoma cruzi proteins to mammalian cells in vitro. Acta Trop (1985) 0.89
Complex lipids as common antigens to Trypanosoma cruzi, T. dionisii, T. vespertilionis and nervous tissue (astrocytes, neurons). Acta Trop (1987) 0.89
Cell-mediated reactivity against human and Trypanosoma cruzi antigens according to clinical status in Chagas' disease patients. Immunol Lett (1985) 0.82
Value of peak exercise oxygen consumption for optimal timing of cardiac transplantation in ambulatory patients with heart failure. Circulation (1991) 4.89
Regulation of repressor expression in lambda. Proc Natl Acad Sci U S A (1970) 3.12
Surface antigen in early differentiation. Proc Natl Acad Sci U S A (1977) 2.83
[On the early regulation of the lambda bacteriophage]. C R Acad Sci Hebd Seances Acad Sci D (1968) 2.52
Establishment of repression by lambdoid phage in catabolite activator protein and adenylate cyclase mutants of Escherichia coli. Proc Natl Acad Sci U S A (1972) 2.20
Modification of T-cell proliferation and interleukin 2 production in mice infected with Trypanosoma cruzi. Proc Natl Acad Sci U S A (1983) 2.17
A randomized active-controlled trial of mycophenolate mofetil in heart transplant recipients. Mycophenolate Mofetil Investigators. Transplantation (1998) 1.97
Bacterial mutants which block phage assembly. J Supramol Struct (1974) 1.91
Myeloproliferative virus, a cloned murine sarcoma virus with spleen focus-forming properties in adult mice. J Virol (1980) 1.85
Major histocompatibility complex (MHC) class I KbDb -/- deficient mice possess functional CD8+ T cells and natural killer cells. Proc Natl Acad Sci U S A (1998) 1.80
Organization of four mouse lambda light chain immunoglobulin genes. Proc Natl Acad Sci U S A (1981) 1.73
The regulation and mechanism of DNA synthesis in bacteriophage lambda. Cold Spring Harb Symp Quant Biol (1968) 1.67
Mutations of coliphage lambda affecting the expression of replicative functions O and P. Mol Gen Genet (1970) 1.66
Chagas disease: a model for the study of autoimmune diseases. Parasitol Today (1989) 1.66
Nonadherence consensus conference summary report. Am J Transplant (2009) 1.61
Synergistic protection by specific antibodies and interferon against infection by Trypanosoma cruzi in vitro. Eur J Immunol (1984) 1.58
DNA rearrangements and antigenic variation in Trypanosoma equiperdum: multiple expression-linked sites in independent isolates of trypanosomes expressing the same antigen. Mol Cell Biol (1983) 1.50
Polyclonal lymphocyte responses to murine Trypanosoma cruzi infection. I. Quantitation of both T- and B-cell responses. Scand J Immunol (1986) 1.46
Appearance of a chromatin protein during the erythroid differentiation of Friend virus-transformed cells. Proc Natl Acad Sci U S A (1977) 1.46
Bidirectional transcription and the regulation of Phage lambda repressor synthesis. Proc Natl Acad Sci U S A (1972) 1.45
Sirolimus conversion after heart transplant: risk factors for acute rejection and predictors of renal function response. Am J Transplant (2014) 1.41
Antigenic polymorphism of Trypanosoma cruzi: clonal analysis of trypomastigote surface antigens. Eur J Immunol (1984) 1.34
Induction of spectrin in erythroleukemic cells transformed by Friend virus. Proc Natl Acad Sci U S A (1977) 1.33
Operator sequences of bacteriophages P22 and 21. J Mol Biol (1980) 1.33
Suppression of polyclonal antibody production in Trypanosoma cruzi-infected mice by treatment with anti-L3T4 antibodies. J Immunol (1987) 1.31
Genomic environment of variant surface antigen genes of Trypanosoma equiperdum. Proc Natl Acad Sci U S A (1983) 1.30
Purification and partial characterization of three extracellular cellulases from Cellulomonas sp. Eur J Biochem (1978) 1.29
Surface changes in differentiating Friend erythroleukemic cells in culture. Cell (1977) 1.28
Active late-appearing variable surface antigen genes in Trypanosoma equiperdum are constructed entirely from pseudogenes. Proc Natl Acad Sci U S A (1989) 1.26
Persistence of polyclonal B cell activation with undetectable parasitemia in late stages of experimental Chagas' disease. J Immunol (1986) 1.24
The genomic organization and transcription of the ubiquitin genes of Trypanosoma cruzi. EMBO J (1988) 1.21
L3T4+ T cells able to mediate parasite-specific delayed-type hypersensitivity play a role in the pathology of experimental Chagas' disease. Eur J Immunol (1987) 1.20
An analysis of the Tro phenotype of bacteriophage lambda. Virology (1979) 1.19
The major 85-kDa surface antigen of the mammalian-stage forms of Trypanosoma cruzi is a family of sialidases. Proc Natl Acad Sci U S A (1991) 1.18
Alternate trans splicing in Trypanosoma equiperdum: implications for splice site selection. Mol Cell Biol (1988) 1.17
The major 85-kD surface antigen of the mammalian form of Trypanosoma cruzi is encoded by a large heterogeneous family of simultaneously expressed genes. J Exp Med (1990) 1.16
Developmental and hormonal regulation of protein H1 degrees in rodents. Proc Natl Acad Sci U S A (1982) 1.14
Antigenic diversity by the recombination of pseudogenes. Genes Dev (1989) 1.12
Isolation and characterization of deletions in bacteriophage lambda residing as prophage in E. coli K 12. Mol Gen Genet (1972) 1.11
Studies of cellular differentiation by automated cell separation. Two model systems: Friend virus-transformed cells and Hydra attenuata. J Histochem Cytochem (1976) 1.11
Very large and isotypically atypical polyclonal plaque-forming cell responses in mice infected with Trypanosoma cruzi. Eur J Immunol (1985) 1.06
The use of incomplete genes for the construction of a Trypanosoma equiperdum variant surface glycoprotein gene. EMBO J (1986) 1.01
Stable expression of two variable surface glycoproteins by cloned Trypanosoma equiperdum. Nature (1986) 1.00
Sodium butyrate inhibits myogenesis by interfering with the transcriptional activation function of MyoD and myogenin. Mol Cell Biol (1992) 1.00
Neuropathy associated with experimental Chagas' disease. Ann Neurol (1985) 0.98
The role of gene cro in phage development. Virology (1975) 0.98
Studies on the E. coli groNB (nusB) gene which affects bacteriophage lambda N gene function. Mol Gen Genet (1980) 0.97
Expression of whole and hybrid genes in Trypanosoma equiperdum antigenic variation. EMBO J (1986) 0.97
[Effects of hexamethylenebisacetamide on the differentiation of embryonal carcinoma cells]. C R Acad Sci Hebd Seances Acad Sci D (1978) 0.97
Lambda phage promoter used to enhance expression of a plasmid-cloned gene. Mol Gen Genet (1978) 0.97
Trypanosome variable surface glycoproteins: composite genes and order of expression. Genes Dev (1990) 0.97
Polyclonal lymphocyte responses to murine Trypanosoma cruzi infection. II. Cytotoxic T lymphocytes. Scand J Immunol (1986) 0.96
An interspecific linkage map of mouse chromosome 15 positioned with respect to the centromere. Genomics (1992) 0.95
Persistence of Trypanosoma cruzi antigens in the inflammatory lesions of chronically infected mice. Trans R Soc Trop Med Hyg (1988) 0.95
On the role of repeated sequences 5' to variant surface glycoprotein genes in African trypanosomes. Gene (1987) 0.95
Susceptible mice present higher macrophage activation than resistant mice during infections with myotropic strains of Trypanosoma cruzi. Parasite Immunol (1989) 0.94
Characterization of a novel biochemical abnormality in galactosemia: deficiency of glycolipids containing galactose or N-acetylgalactosamine and accumulation of precursors in brain and lymphocytes. Biochem Med Metab Biol (1991) 0.94
A family of genes related to a new expression site-associated gene in Trypanosoma equiperdum. Mol Cell Biol (1991) 0.94
Sulfated lipids represent common antigens on the surface of Trypanosoma cruzi and mammalian tissues. Mol Biochem Parasitol (1988) 0.93
Stability of expression-linked surface antigen gene in Trypanosoma equiperdum. Nature (1984) 0.93
T lymphocyte function during experimental Chagas' disease: production of and response to interleukin 2. Eur J Immunol (1985) 0.93
Host interference with expression of the lambda N gene product. Biochimie (1974) 0.93
Effects of butyric acid on cell cycle regulation and induction of histone H1(0) in mouse cells and tissue culture. Inducibility of H1 (0)in the late S-G2 phase of the cell cycle. J Mol Biol (1985) 0.92
Exposed epitopes on a Trypanosoma equiperdum variant surface glycoprotein altered by point mutations. EMBO J (1991) 0.91
DNA rearrangements and antigenic variation in Trypanosoma equiperdum: expression-independent DNA rearrangements in the basic copy of a variant surface glycoprotein gene. Mol Cell Biol (1983) 0.91
Re-expression of an inactivated variable surface glycoprotein gene in Trypanosoma equiperdum. Gene (1984) 0.90
Prostaglandin E1, an inducer of erythroid differentiation of Friend erythroleukemia cells. Exp Cell Res (1977) 0.90
Tetrahymena pyriformis recovers from antibody immobilisation by producing univalent antibody fragments. Nature (1977) 0.90
Infective endocarditis following orthotopic heart transplantation: 10 cases and a review of the literature. Transpl Infect Dis (2004) 0.89
Cellular immunity to Trypanosoma cruzi is mediated by helper T cells (CD4+). Trans R Soc Trop Med Hyg (1988) 0.89
The trypanosome VSG expression site encodes adenylate cyclase and a leucine-rich putative regulatory gene. EMBO J (1991) 0.89
Proteolytic cleavage of IgG bound to the Fc receptor of Schistosoma mansoni schistosomula. Parasite Immunol (1981) 0.89
Evaluation of recombinant trypomastigote surface antigens of Trypanosoma cruzi in screening sera from a population in rural northeastern Brazil endemic for Chagas' disease. Acta Trop (1992) 0.88
Acute hormonal regulation of cyclic AMP content and glycogen phosphorylase activity in fetal liver in organ culture. Endocrinology (1974) 0.88
Characterization of the Trypanosoma cruzi Cdc2p-related protein kinase 1 and identification of three novel associating cyclins. Mol Biochem Parasitol (2001) 0.87
Distribution of IP25 in chromatin and its possible involvement in chromatin condensation. Biochem Biophys Res Commun (1981) 0.87
Antigenic variation in Trypanosoma equiperdum. Res Microbiol (1992) 0.87
Transplantation of the canine larynx. Ann Surg (1970) 0.87
An evaluation of several adjuvant emulsion regimens for the production of polyclonal antisera in rabbits. Lab Anim Sci (1991) 0.85
Proliferation signal inhibitors in transplantation: questions at the cutting edge of everolimus therapy. Transplant Proc (2007) 0.84
Cloning and characterization of a variant surface glycoprotein expression site from Trypanosoma equiperdum. Mol Cell Biol (1986) 0.83
SA85-1 proteins of Trypanosoma cruzi lack sialidase activity. Mol Biochem Parasitol (1993) 0.83
An IS4 transposition causes a 13-bp duplication of phage lambda DNA and results in the constitutive expression of the cI and cro gene products. Gene (1982) 0.83
Terminal erythroid differentiation in normal and leukemic mouse cells. Blood Cells (1978) 0.82
Mutants in the y region of bacteriophage lambda constitutive for repressor synthesis: their isolation and the characterization of the Hyp phenotype. Gene (1982) 0.82
Cro mutants of phage 434. Virology (1975) 0.82
Purification and properties of phage P22 c2 repressor. Eur J Biochem (1978) 0.81
[On the replication of the lambda bacteriophage]. C R Acad Sci Hebd Seances Acad Sci D (1968) 0.81
Randomized controlled trial of sirolimus conversion in cardiac transplant recipients with renal insufficiency. Am J Transplant (2012) 0.81
Skewed V beta TCR repertoire of CD8+ T cells in murine Trypanosoma cruzi infection. Int Immunol (1994) 0.81
Heart transplantation in patients requiring preoperative mechanical support. J Heart Transplant (1988) 0.81
Biochemical properties and localization of the chromosomal protein IP25. Eur J Biochem (1979) 0.80
Purification and properties of coliphage 21 repressor. Eur J Biochem (1977) 0.80
Sarcoidosis of the central nervous system. J Comput Assist Tomogr (1979) 0.80
Cell cycle regulation of histone H1O in CHO cells: a flow cytofluorimetric study after double staining of the cells. EMBO J (1983) 0.80
Influence of dispersion method on dissolution rate and bioavailability of digoxin from triturations and compressed tablets II. J Pharm Sci (1974) 0.80
Noninvasive rejection monitoring of cardiac transplants using high resolution intramyocardial electrograms: initial US multicenter experience. Pacing Clin Electrophysiol (1998) 0.79
Polyreactive autoantibodies to negatively charged epitopes following Trypanosoma cruzi infection. Eur J Immunol (1992) 0.79
Deletions of lambda phage locating a prm mutation within the rightward operator. Proc Natl Acad Sci U S A (1976) 0.79
Growth properties of Cellulomonas flavigena mutants affected in cellulose utilization. J Bacteriol (1978) 0.79