Butyrate modulates antioxidant enzyme expression in malignant and non-malignant human colon tissues.

PubWeight™: 0.77‹?›

🔗 View Article (PMID 24677319)

Published in Mol Carcinog on March 28, 2014

Authors

Franziska Jahns1, Anne Wilhelm, Nadja Jablonowski, Henning Mothes, Karl Otto Greulich, Michael Glei

Author Affiliations

1: Department of Nutritional Toxicology, Institute of Nutrition, Friedrich Schiller University Jena, Jena, Germany; Department of Single Cell and Single Molecule Techniques, Leibniz Institute for Age Research - Fritz Lipmann Institute, Jena, Germany.

Articles by these authors

Chicken cecum immune response to Salmonella enterica serovars of different levels of invasiveness. Infect Immun (2007) 1.38

The facultative intracellular pathogen Candida glabrata subverts macrophage cytokine production and phagolysosome maturation. J Immunol (2011) 1.33

Associations between dietary habits and body mass index with gut microbiota composition and fecal water genotoxicity: an observational study in African American and Caucasian American volunteers. Nutr J (2009) 1.30

Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre. Mutat Res (2009) 1.27

Influence of prebiotics and antioxidants in bread on the immune system, antioxidative status and antioxidative capacity in male smokers and non-smokers. Br J Nutr (2007) 1.24

After double-strand break induction by UV-A, homologous recombination and nonhomologous end joining cooperate at the same DSB if both systems are available. J Cell Sci (2004) 1.20

Candida albicans-epithelial interactions: dissecting the roles of active penetration, induced endocytosis and host factors on the infection process. PLoS One (2012) 1.12

Efficacy of major general surgery performed by non-physician clinicians at a central hospital in Malawi. Trop Doct (2011) 1.07

Different expression of calgizzarin (S100A11) in normal colonic epithelium, adenoma and colorectal carcinoma. Int J Oncol (2006) 1.06

Discovery and identification of alpha-defensins as low abundant, tumor-derived serum markers in colorectal cancer. Gastroenterology (2005) 1.03

Butyrate is only one of several growth inhibitors produced during gut flora-mediated fermentation of dietary fibre sources. Br J Nutr (2003) 1.01

Differential diagnosis of thyroid nodules via real-time PET/ultrasound (US) fusion in a case of co-existing medullary thyroid cancer and adenoma. J Clin Endocrinol Metab (2013) 0.97

The Amsterdam Declaration on Essential Surgical Care. World J Surg (2015) 0.91

New revival of an old biomarker: characterisation of buccal cells and determination of genetic damage in the isolated fraction of viable leucocytes. Mutat Res (2003) 0.90

Effects of fatty acids on metabolism and cell growth of human colon cell lines of different transformation state. Biofactors (2009) 0.89

Fish fatty acids alter markers of apoptosis in colorectal adenoma and adenocarcinoma cell lines but fish consumption has no impact on apoptosis-induction ex vivo. Apoptosis (2010) 0.87

Impact of butyrate on PKM2 and HSP90β expression in human colon tissues of different transformation stages: a comparison of gene and protein data. Genes Nutr (2011) 0.87

Proapoptotic effects of long-chain vitamin E metabolites in HepG2 cells are mediated by oxidative stress. Free Radic Biol Med (2010) 0.86

First molecular cytogenetic high resolution characterization of the NIH 3T3 cell line by murine multicolor banding. J Histochem Cytochem (2013) 0.86

Comet-FISH using peptide nucleic acid probes detects telomeric repeats in DNA damaged by bleomycin and mitomycin C proportional to general DNA damage. Mutagenesis (2004) 0.85

Immune evasion, stress resistance, and efficient nutrient acquisition are crucial for intracellular survival of Candida glabrata within macrophages. Eukaryot Cell (2013) 0.85

Genotoxicity of 4-hydroxy-2-nonenal in human colon tumor cells is associated with cellular levels of glutathione and the modulation of glutathione S-transferase A4 expression by butyrate. Toxicol Sci (2005) 0.85

Fecal water as a non-invasive biomarker in nutritional intervention: comparison of preparation methods and refinement of different endpoints. Nutr Cancer (2007) 0.84

Fragility of telomeres after bleomycin and cisplatin combined treatment measured in human leukocytes with the Comet-FISH technique. Exp Oncol (2005) 0.84

2-Dodecylcyclobutanone, a radiolytic product of palmitic acid, is genotoxic in primary human colon cells and in cells from preneoplastic lesions. Mutat Res (2005) 0.84

Fermentation products of inulin-type fructans reduce proliferation and induce apoptosis in human colon tumour cells of different stages of carcinogenesis. Br J Nutr (2009) 0.82

Proteomic identification of PSF and p54(nrb) as TopBP1-interacting proteins. J Cell Biochem (2012) 0.82

Intervention with cloudy apple juice results in altered biological activities of ileostomy samples collected from individual volunteers. Eur J Nutr (2008) 0.82

Apple polyphenols and products formed in the gut differently inhibit survival of human cell lines derived from colon adenoma (LT97) and carcinoma (HT29). J Agric Food Chem (2007) 0.81

The comet-FISH technique: a tool for detection of specific DNA damage and repair. Methods Mol Biol (2005) 0.80

Human colon cell culture models of different transformation stages to assess conjugated linoleic acid and conjugated linolenic acid metabolism: Challenges and chances. Toxicol In Vitro (2012) 0.79

Impact of polyphenol metabolites produced by colonic microbiota on expression of COX-2 and GSTT2 in human colon cells (LT97). Nutr Cancer (2011) 0.79

A direct view by immunofluorescent comet assay (IFCA) of DNA damage induced by nicking and cutting enzymes, ionizing (137)Cs radiation, UV-A laser microbeam irradiation and the radiomimetic drug bleomycin. Mutagenesis (2009) 0.79

Influence of inorganic and organic iron compounds on parameters of cell growth and survival in human colon cells. Toxicol In Vitro (2009) 0.79

Increasing fish consumption does not affect genotoxicity markers in the colon in an intervention study. Carcinogenesis (2009) 0.79

Gene expression profiles in human peripheral blood mononuclear cells as biomarkers for nutritional in vitro and in vivo investigations. Genes Nutr (2010) 0.79

Colon cancer risk factors from nutrition. Anal Bioanal Chem (2003) 0.79

In vitro fermented nuts exhibit chemopreventive effects in HT29 colon cancer cells. Br J Nutr (2011) 0.79

Uranyl nitrilotriacetate, a stabilized salt of uranium, is genotoxic in nontransformed human colon cells and in the human colon adenoma cell line LT97. Toxicol Sci (2006) 0.79

Fermented wheat aleurone enriched with probiotic strains LGG and Bb12 modulates markers of tumor progression in human colon cells. Nutr Cancer (2011) 0.78

Impact of apple polyphenols on GSTT2 gene expression, subsequent protection of DNA and modulation of proliferation using LT97 human colon adenoma cells. Mol Nutr Food Res (2009) 0.78

Effects of synbiotic fermentation products on primary chemoprevention in human colon cells. J Nutr Biochem (2011) 0.78

Laser microbeams and optical tweezers in ageing research. Chemphyschem (2009) 0.78

Detection of DNA damage by comet fluorescence in situ hybridization. Methods Mol Biol (2012) 0.78

Fermentation supernatants of wheat ( Triticum aestivum L.) aleurone beneficially modulate cancer progression in human colon cells. J Agric Food Chem (2010) 0.78

Butyrate reduces the frequency of micronuclei in human colon carcinoma cells in vitro. Toxicol In Vitro (2009) 0.77

Blood mononucleocytes are sensitive to the DNA damaging effects of iron overload--in vitro and ex vivo results with human and rat cells. Mutat Res (2007) 0.77

Direct Microscopic Observation of the Time Course of Single-Molecule DNA Restriction Reactions We thank Dr. Werner Wolf for helpful discussions and the VW-foundation, Grant No. I/75099 for supporting this work. Angew Chem Int Ed Engl (2001) 0.77

Chemopreventive effects of in vitro digested and fermented bread in human colon cells. Eur J Nutr (2011) 0.77

GSTT2, a phase II gene induced by apple polyphenols, protects colon epithelial cells against genotoxic damage. Mol Nutr Food Res (2009) 0.77

Modification of an in vitro model simulating the whole digestive process to investigate cellular endpoints of chemoprevention. Br J Nutr (2011) 0.76

Blackcurrant seed press residue increases tocopherol concentrations in serum and stool whilst biomarkers in stool and urine indicate increased oxidative stress in human subjects. Br J Nutr (2009) 0.76

Modulation of gene expression in eicosapentaenoic acid and docosahexaenoic acid treated human colon adenoma cells. Genes Nutr (2009) 0.76

Does an extract of carob (Ceratonia siliqua L.) have chemopreventive potential related to oxidative stress and drug metabolism in human colon cells? J Agric Food Chem (2009) 0.76

Comet fluorescence in situ hybridization (Comet-FISH): detection of DNA damage. Cold Spring Harb Protoc (2009) 0.76

Fermented wheat aleurone induces enzymes involved in detoxification of carcinogens and in antioxidative defence in human colon cells. Br J Nutr (2010) 0.76

Gut fermentation products of inulin-type fructans modulate the expression of xenobiotic-metabolising enzymes in human colonic tumour cells. Anticancer Res (2012) 0.76

Defensin alpha 6 (DEFA 6) overexpression threshold of over 60 fold can distinguish between adenoma and fully blown colon carcinoma in individual patients. BMC Cancer (2010) 0.76

Fermented wheat aleurone inhibits growth and induces apoptosis in human HT29 colon adenocarcinoma cells. Br J Nutr (2009) 0.76

New insight into the influence of carob extract and gallic acid on hemin induced modulation of HT29 cell growth parameters. Toxicol In Vitro (2009) 0.75

Clotrimazole dampens vaginal inflammation and neutrophil infiltration in response to Candida albicans infection. Antimicrob Agents Chemother (2013) 0.75

Readout of protein microarrays using intrinsic time resolved UV fluorescence for label-free detection. Proteomics (2004) 0.75

Molecular cytogenetic evaluation of the efficacy of photodynamic therapy by indocyanine green in breast adenocarcinoma MCF-7 cells. Photodiagnosis Photodyn Ther (2012) 0.75

Orientation of erythrocytes in optical trap revealed by confocal fluorescence microscopy. J Biomed Opt (2007) 0.75

Practical aspects of working with laser microbeams and optical tweezers: data and equations. Methods Cell Biol (2007) 0.75

Ubiquitous cancer genes: multipurpose molecules for protein micro-arrays. Proteomics (2006) 0.75