Human colon cell culture models of different transformation stages to assess conjugated linoleic acid and conjugated linolenic acid metabolism: Challenges and chances.

PubWeight™: 0.79‹?›

🔗 View Article (PMID 22584027)

Published in Toxicol In Vitro on May 11, 2012

Authors

Christian Degen1, Nina Habermann, Stefanie Piegholdt, Michael Glei, Gerhard Jahreis

Author Affiliations

1: Department of Nutritional Physiology, Institute of Nutrition, Friedrich-Schiller-University Jena, Dornburger Str. 24, 07743 Jena, Germany. b0dech@uni-jena.de

Articles by these authors

Macular xanthophylls and ω-3 long-chain polyunsaturated fatty acids in age-related macular degeneration: a randomized trial. JAMA Ophthalmol (2013) 2.04

Tumor-infiltrating lymphocytes in colorectal tumors display a diversity of T cell receptor sequences that differ from the T cells in adjacent mucosal tissue. Cancer Immunol Immunother (2013) 1.53

Dietary intervention with the probiotics Lactobacillus acidophilus 145 and Bifidobacterium longum 913 modulates the potential of human faecal water to induce damage in HT29clone19A cells. Br J Nutr (2004) 1.53

Associations between dietary habits and body mass index with gut microbiota composition and fecal water genotoxicity: an observational study in African American and Caucasian American volunteers. Nutr J (2009) 1.30

Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre. Mutat Res (2009) 1.27

Influence of prebiotics and antioxidants in bread on the immune system, antioxidative status and antioxidative capacity in male smokers and non-smokers. Br J Nutr (2007) 1.24

Review of mass spectrometry-based metabolomics in cancer research. Cancer Epidemiol Biomarkers Prev (2013) 1.03

Butyrate is only one of several growth inhibitors produced during gut flora-mediated fermentation of dietary fibre sources. Br J Nutr (2003) 1.01

Cholesterol metabolism is affected by calcium phosphate supplementation in humans. J Nutr (2005) 1.00

trans Palmitoleic acid arises endogenously from dietary vaccenic acid. Am J Clin Nutr (2014) 0.98

Apple flavonoids inhibit growth of HT29 human colon cancer cells and modulate expression of genes involved in the biotransformation of xenobiotics. Mol Carcinog (2006) 0.96

Evaluation of suppressive and pro-resolving effects of EPA and DHA in human primary monocytes and T-helper cells. J Lipid Res (2013) 0.95

Differences in CLA isomer distribution of cow's milk lipids. Lipids (2003) 0.95

Randomized placebo-controlled intervention with n-3 LC-PUFA-supplemented yoghurt: effects on circulating eicosanoids and cardiovascular risk factors. Clin Nutr (2012) 0.94

Trans-11-18 : 1 is effectively Delta9-desaturated compared with trans-12-18 : 1 in humans. Br J Nutr (2006) 0.94

C57Bl/6 N mice on a western diet display reduced intestinal and hepatic cholesterol levels despite a plasma hypercholesterolemia. BMC Genomics (2012) 0.93

Bread enriched with green coffee extract has chemoprotective and antigenotoxic activities in human cells. Nutr Cancer (2006) 0.92

Dietary supplementation with 11trans- and 12trans-18:1 and oxidative stress in humans. Am J Clin Nutr (2006) 0.92

Randomized controlled trial to evaluate the effects of progressive resistance training compared to progressive muscle relaxation in breast cancer patients undergoing adjuvant radiotherapy: the BEST study. BMC Cancer (2013) 0.91

Determination of underivatised sterols and bile acid trimethyl silyl ether methyl esters by gas chromatography-mass spectrometry-single ion monitoring in faeces. J Chromatogr B Analyt Technol Biomed Life Sci (2004) 0.91

Long-term moderate intervention with n-3 long-chain PUFA-supplemented dairy products: effects on pathophysiological biomarkers in patients with rheumatoid arthritis. Br J Nutr (2009) 0.90

New revival of an old biomarker: characterisation of buccal cells and determination of genetic damage in the isolated fraction of viable leucocytes. Mutat Res (2003) 0.90

Analysis of conjugated linoleic acid and trans 18:1 isomers in synthetic and animal products. Am J Clin Nutr (2004) 0.90

Cis-9,trans-11-conjugated linoleic acid inhibits allergic sensitization and airway inflammation via a PPARgamma-related mechanism in mice. J Nutr (2008) 0.90

Nutritional evaluation of rapeseed protein compared to soy protein for quality, plasma amino acids, and nitrogen balance--a randomized cross-over intervention study in humans. Clin Nutr (2012) 0.90

Effects of polydextrose supplementation on different faecal parameters in healthy volunteers. Int J Food Sci Nutr (2008) 0.89

Prevention of colitis-associated carcinogenesis in a mouse model by diet supplementation with ursodeoxycholic acid. Int J Cancer (2006) 0.89

Effects of fatty acids on metabolism and cell growth of human colon cell lines of different transformation state. Biofactors (2009) 0.89

Fatty acid distribution of cord and maternal blood in human pregnancy: special focus on individual trans fatty acids and conjugated linoleic acids. Lipids Health Dis (2011) 0.89

Trans fatty acid isomers and the trans-9/trans-11 index in fat containing foods. Eur J Lipid Sci Technol (2011) 0.88

Survey of n-3 and n-6 polyunsaturated fatty acids in fish and fish products. Lipids Health Dis (2012) 0.88

Gene expression changes in adipose tissue with diet- and/or exercise-induced weight loss. Cancer Prev Res (Phila) (2013) 0.87

Vaccenic acid-mediated reduction in cytokine production is independent of c9,t11-CLA in human peripheral blood mononuclear cells. Biochim Biophys Acta (2012) 0.87

Fish fatty acids alter markers of apoptosis in colorectal adenoma and adenocarcinoma cell lines but fish consumption has no impact on apoptosis-induction ex vivo. Apoptosis (2010) 0.87

Impact of butyrate on PKM2 and HSP90β expression in human colon tissues of different transformation stages: a comparison of gene and protein data. Genes Nutr (2011) 0.87

Cis-9,trans-11-CLA exerts anti-inflammatory effects in human bronchial epithelial cells and eosinophils: comparison to trans-10,cis-12-CLA and to linoleic acid. Biochim Biophys Acta (2005) 0.86

Apple polyphenols modulate expression of selected genes related to toxicological defence and stress response in human colon adenoma cells. Int J Cancer (2008) 0.86

A combination of calcium phosphate and probiotics beneficially influences intestinal lactobacilli and cholesterol metabolism in humans. Clin Nutr (2011) 0.86

Trans-10,cis-12-CLA-caused lipodystrophy is associated with profound changes of fatty acid profiles of liver, white adipose tissue and erythrocytes in mice: possible link to tissue-specific alterations of fatty acid desaturation. Ann Nutr Metab (2010) 0.86

Dietary supplementation with trans-11- and trans-12-18 : 1 increases cis-9, trans-11-conjugated linoleic acid in human immune cells, but without effects on biomarkers of immune function and inflammation. Br J Nutr (2007) 0.86

Proapoptotic effects of long-chain vitamin E metabolites in HepG2 cells are mediated by oxidative stress. Free Radic Biol Med (2010) 0.86

First molecular cytogenetic high resolution characterization of the NIH 3T3 cell line by murine multicolor banding. J Histochem Cytochem (2013) 0.86

n-3 LC-PUFA-enriched dairy products are able to reduce cardiovascular risk factors: a double-blind, cross-over study. Clin Nutr (2010) 0.86

Intestinal steroid profiles and microbiota composition in colitic mice. Gut Microbes (2011) 0.85

Genotoxicity of 4-hydroxy-2-nonenal in human colon tumor cells is associated with cellular levels of glutathione and the modulation of glutathione S-transferase A4 expression by butyrate. Toxicol Sci (2005) 0.85

Incorporation of n-3 PUFA and γ-linolenic acid in blood lipids and red blood cell lipids together with their influence on disease activity in patients with chronic inflammatory arthritis--a randomized controlled human intervention trial. Lipids Health Dis (2011) 0.85

Nutritional and toxicological importance of macro, trace, and ultra-trace elements in algae food products. J Agric Food Chem (2007) 0.85

Dietary echium oil increases long-chain n-3 PUFAs, including docosapentaenoic acid, in blood fractions and alters biochemical markers for cardiovascular disease independently of age, sex, and metabolic syndrome. J Nutr (2014) 0.84

Inactivation of hepatitis C virus infectivity by human breast milk. J Infect Dis (2013) 0.84

2-Dodecylcyclobutanone, a radiolytic product of palmitic acid, is genotoxic in primary human colon cells and in cells from preneoplastic lesions. Mutat Res (2005) 0.84

Fecal water as a non-invasive biomarker in nutritional intervention: comparison of preparation methods and refinement of different endpoints. Nutr Cancer (2007) 0.84

2-Propanol in the mobile phase reduces the time of analysis of CLA isomers by silver ion-HPLC. J Chromatogr B Analyt Technol Biomed Life Sci (2010) 0.83

Intervention with cloudy apple juice results in altered biological activities of ileostomy samples collected from individual volunteers. Eur J Nutr (2008) 0.82

Assessment of the oxidative stability of conventional and high-oleic sunflower oil by means of solid-phase microextraction-gas chromatography. Int J Food Sci Nutr (2011) 0.82

Effects of fat-modified dairy products on blood lipids in humans in comparison with other fats. Ann Nutr Metab (2005) 0.82

Dietary rapeseed/canola-oil supplementation reduces serum lipids and liver enzymes and alters postprandial inflammatory responses in adipose tissue compared to olive-oil supplementation in obese men. Mol Nutr Food Res (2014) 0.82

Fermentation products of inulin-type fructans reduce proliferation and induce apoptosis in human colon tumour cells of different stages of carcinogenesis. Br J Nutr (2009) 0.82

Extensive analysis of long-chain polyunsaturated fatty acids, CLA, trans-18:1 isomers, and plasmalogenic lipids in different retail beef types. J Agric Food Chem (2008) 0.82

Association of dietary, circulating, and supplement fatty acids with coronary risk. Ann Intern Med (2014) 0.82

Metabolic and growth inhibitory effects of conjugated fatty acids in the cell line HT-29 with special regard to the conversion of t11,t13-CLA. Biochim Biophys Acta (2011) 0.82

Cis-9,trans-11-conjugated linoleic acid affects lipid raft composition and sensitizes human colorectal adenocarcinoma HT-29 cells to X-radiation. Biochim Biophys Acta (2012) 0.82

Apple polyphenols and products formed in the gut differently inhibit survival of human cell lines derived from colon adenoma (LT97) and carcinoma (HT29). J Agric Food Chem (2007) 0.81

Benefits of foods supplemented with vegetable oils rich in α-linolenic, stearidonic or docosahexaenoic acid in hypertriglyceridemic subjects: a double-blind, randomized, controlled trail. Eur J Nutr (2014) 0.81

The formation of short-chain fatty acids is positively associated with the blood lipid-lowering effect of lupin kernel fiber in moderately hypercholesterolemic adults. J Nutr (2014) 0.81

Absorption of black currant anthocyanins by monolayers of human intestinal epithelial Caco-2 cells mounted in ussing type chambers. J Agric Food Chem (2008) 0.80

Flow cytometric quantification of chlamydial infection in cell culture. J Microbiol Methods (2009) 0.80

Fatty acid profiles and antioxidants of organic and conventional milk from low- and high-input systems during outdoor period. J Sci Food Agric (2014) 0.80

Faecal steroid excretion in humans is affected by calcium supplementation and shows gender-specific differences. Eur J Nutr (2008) 0.80

High content of long-chain n-3 polyunsaturated fatty acids in red blood cells of Kenyan Maasai despite low dietary intake. Lipids Health Dis (2011) 0.80

Influence of nutritional recovery on the leptin axis in severely malnourished children. J Clin Endocrinol Metab (2005) 0.80

Searching for health beneficial n-3 and n-6 fatty acids in plant seeds. Eur J Lipid Sci Technol (2012) 0.80

Human intestinal fatty acid binding protein 2 expression is associated with fat intake and polymorphisms. J Nutr (2010) 0.79

Influence of inorganic and organic iron compounds on parameters of cell growth and survival in human colon cells. Toxicol In Vitro (2009) 0.79

Work and diet-related risk factors of cardiovascular diseases: comparison of two occupational groups. J Occup Med Toxicol (2010) 0.79

Gene expression profiles in human peripheral blood mononuclear cells as biomarkers for nutritional in vitro and in vivo investigations. Genes Nutr (2010) 0.79

Influence of in vitro supplementation with lipids from conventional and Alpine milk on fatty acid distribution and cell growth of HT-29 cells. Lipids Health Dis (2011) 0.79

Food derived microRNAs. Food Funct (2015) 0.79

Increasing fish consumption does not affect genotoxicity markers in the colon in an intervention study. Carcinogenesis (2009) 0.79

Colon cancer risk factors from nutrition. Anal Bioanal Chem (2003) 0.79

Impact of polyphenol metabolites produced by colonic microbiota on expression of COX-2 and GSTT2 in human colon cells (LT97). Nutr Cancer (2011) 0.79

In vitro fermented nuts exhibit chemopreventive effects in HT29 colon cancer cells. Br J Nutr (2011) 0.79

Uranyl nitrilotriacetate, a stabilized salt of uranium, is genotoxic in nontransformed human colon cells and in the human colon adenoma cell line LT97. Toxicol Sci (2006) 0.79

Impact of apple polyphenols on GSTT2 gene expression, subsequent protection of DNA and modulation of proliferation using LT97 human colon adenoma cells. Mol Nutr Food Res (2009) 0.78

Progressive resistance versus relaxation training for breast cancer patients during adjuvant chemotherapy: design and rationale of a randomized controlled trial (BEATE study). Contemp Clin Trials (2012) 0.78

Fermentation supernatants of wheat ( Triticum aestivum L.) aleurone beneficially modulate cancer progression in human colon cells. J Agric Food Chem (2010) 0.78

Fatty acid profile and proliferation of bovine blood mononuclear cells after conjugated linoleic acid supplementation. Lipids Health Dis (2012) 0.78

Fermented wheat aleurone enriched with probiotic strains LGG and Bb12 modulates markers of tumor progression in human colon cells. Nutr Cancer (2011) 0.78

Effects of synbiotic fermentation products on primary chemoprevention in human colon cells. J Nutr Biochem (2011) 0.78

Nanoscale and customary non-esterified sitosterols are equally enriched in different body compartments of the guinea pig. Mol Nutr Food Res (2007) 0.78

Effects of long-term supplementation of dairy cow diets with rumen-protected conjugated linoleic acids (CLA) on performance, metabolic parameters and fatty acid profile in milk fat. Arch Anim Nutr (2011) 0.78

Postprandial effects of calcium phosphate supplementation on plasma concentration-double-blind, placebo-controlled cross-over human study. Nutr J (2013) 0.78

Detection of DNA damage by comet fluorescence in situ hybridization. Methods Mol Biol (2012) 0.78

[Time trends and seasonal variation of iodine content in German cow's milk--investigations from Northrhine-Westfalia]. Berl Munch Tierarztl Wochenschr (2012) 0.78

Lupin protein positively affects plasma LDL cholesterol and LDL:HDL cholesterol ratio in hypercholesterolemic adults after four weeks of supplementation: a randomized, controlled crossover study. Nutr J (2013) 0.78

Dietetic effects of oral intervention with mare's milk on the Severity Scoring of Atopic Dermatitis, on faecal microbiota and on immunological parameters in patients with atopic dermatitis. Int J Food Sci Nutr (2009) 0.78