Published in Genes (Basel) on March 28, 2013
Altered lysosomal proteins in neural-derived plasma exosomes in preclinical Alzheimer disease. Neurology (2015) 1.20
Mesenchymal Stem Cell-derived Extracellular Vesicles: Toward Cell-free Therapeutic Applications. Mol Ther (2015) 1.02
Highly skewed distribution of miRNAs and proteins between colorectal cancer cells and their exosomes following Cetuximab treatment: biomolecular, genetic and translational implications. Oncoscience (2014) 0.97
Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges. Acta Pharm Sin B (2016) 0.83
A principle of organization which facilitates broad Lamarckian-like adaptations by improvisation. Biol Direct (2015) 0.83
Rapid and comprehensive 'shotgun' lipidome profiling of colorectal cancer cell derived exosomes. Methods (2015) 0.82
Relevance of splicing on tumor-released exosome landscape: implications in cancer therapeutics. Front Endocrinol (Lausanne) (2014) 0.81
Exosomes in Human Immunodeficiency Virus Type I Pathogenesis: Threat or Opportunity? Adv Virol (2016) 0.80
MicroRNAs in the Cholangiopathies: Pathogenesis, Diagnosis, and Treatment. J Clin Med (2015) 0.79
Exosomes as renal inductive signals in health and disease, and their application as diagnostic markers and therapeutic agents. Front Cell Dev Biol (2015) 0.79
STIM1/ORAI1-mediated Ca2+ Influx Regulates Enolase-1 Exteriorization. J Biol Chem (2015) 0.79
Diagnosing Lung Cancers through Examination of Micro-RNA Biomarkers in Blood, Plasma, Serum and Sputum: A Review and Summary of Current Literature. Int J Mol Sci (2016) 0.79
Extracellular Vesicles as New Players in Cellular Senescence. Int J Mol Sci (2016) 0.78
Exosome-mediated communication in the ovarian follicle. J Assist Reprod Genet (2016) 0.77
Amnion-Epithelial-Cell-Derived Exosomes Demonstrate Physiologic State of Cell under Oxidative Stress. PLoS One (2016) 0.77
Biobanking of Exosomes in the Era of Precision Medicine: Are We There Yet? Int J Mol Sci (2015) 0.76
Breast Cancer-Derived Extracellular Vesicles: Characterization and Contribution to the Metastatic Phenotype. Biomed Res Int (2015) 0.76
A preliminary proteomic characterisation of extracellular vesicles released by the ovine parasitic nematode, Teladorsagia circumcincta. Vet Parasitol (2016) 0.76
Glypican-1 as a Biomarker for Prostate Cancer: Isolation and Characterization. J Cancer (2016) 0.75
Current Perspectives on In Vivo Noninvasive Tracking of Extracellular Vesicles with Molecular Imaging. Biomed Res Int (2017) 0.75
Exosomes in the Diseased Brain: First Insights from In vivo Studies. Front Neurosci (2017) 0.75
Telocytes and Their Extracellular Vesicles-Evidence and Hypotheses. Int J Mol Sci (2016) 0.75
Nanoscale Extracellular Vesicle Analysis in Alzheimer's Disease Diagnosis and Therapy. Int J Alzheimers Dis (2016) 0.75
The Role of Eukaryotic and Prokaryotic ABC Transporter Family in Failure of Chemotherapy. Front Pharmacol (2017) 0.75
Cambinol, a novel inhibitor of neutral sphingomyelinase 2 shows neuroprotective properties. PLoS One (2015) 0.75
Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Oncotarget (2016) 0.75
Exosomal tetraspanins mediate cancer metastasis by altering host microenvironment. Oncotarget (2017) 0.75
Phytoagent Deoxyelephantopin and Its Derivative Inhibit Triple Negative Breast Cancer Cell Activity through ROS-Mediated Exosomal Activity and Protein Functions. Front Pharmacol (2017) 0.75
Secretory carrier membrane protein 5 is an autophagy inhibitor that promotes the secretion of α-synuclein via exosome. PLoS One (2017) 0.75
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol (2007) 37.10
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol (2008) 19.86
Membrane vesicles as conveyors of immune responses. Nat Rev Immunol (2009) 14.72
Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr Protoc Cell Biol (2006) 13.29
B lymphocytes secrete antigen-presenting vesicles. J Exp Med (1996) 11.53
Receptor downregulation and multivesicular-body sorting. Nat Rev Mol Cell Biol (2002) 10.12
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes. Nat Biotechnol (2011) 9.68
Ceramide triggers budding of exosome vesicles into multivesicular endosomes. Science (2008) 9.42
Secretory mechanisms and intercellular transfer of microRNAs in living cells. J Biol Chem (2010) 8.09
Exosomes--vesicular carriers for intercellular communication. Curr Opin Cell Biol (2009) 6.96
Functional delivery of viral miRNAs via exosomes. Proc Natl Acad Sci U S A (2010) 6.72
Exosomes: extracellular organelles important in intercellular communication. J Proteomics (2010) 6.47
Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles. J Immunol (2001) 6.32
Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. Nat Commun (2011) 5.95
Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Nat Med (2001) 5.71
Exosomes: endosomal-derived vesicles shipping extracellular messages. Curr Opin Cell Biol (2004) 5.71
Rab27a and Rab27b control different steps of the exosome secretion pathway. Nat Cell Biol (2009) 5.44
Cells release prions in association with exosomes. Proc Natl Acad Sci U S A (2004) 5.17
Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Nat Cell Biol (2012) 5.12
Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). J Biol Chem (1987) 4.99
Role of LBPA and Alix in multivesicular liposome formation and endosome organization. Science (2004) 4.35
Exosomes and HIV Gag bud from endosome-like domains of the T cell plasma membrane. J Cell Biol (2006) 4.33
Exosomes: proteomic insights and diagnostic potential. Expert Rev Proteomics (2009) 4.27
Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury. Stem Cell Res (2010) 4.06
Protein sorting into multivesicular endosomes. Curr Opin Cell Biol (2003) 4.04
Alzheimer's disease beta-amyloid peptides are released in association with exosomes. Proc Natl Acad Sci U S A (2006) 3.98
Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes. J Cell Biol (1996) 3.88
Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival. J Neurosci (2010) 3.81
Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis. Nanomedicine (2011) 3.79
Indirect activation of naïve CD4+ T cells by dendritic cell-derived exosomes. Nat Immunol (2002) 3.78
ExoCarta: A compendium of exosomal proteins and RNA. Proteomics (2009) 3.72
Endocytosis, intracellular sorting, and processing of exosomes by dendritic cells. Blood (2004) 3.68
Exosome secretion: molecular mechanisms and roles in immune responses. Traffic (2011) 3.36
ExoCarta 2012: database of exosomal proteins, RNA and lipids. Nucleic Acids Res (2011) 3.28
TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. J Immunol (2002) 3.28
The regulation of exosome secretion: a novel function of the p53 protein. Cancer Res (2006) 3.22
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. PLoS Biol (2012) 3.18
Murine mammary carcinoma exosomes promote tumor growth by suppression of NK cell function. J Immunol (2006) 3.12
Exosomes are released by cultured cortical neurones. Mol Cell Neurosci (2006) 3.07
Human tumor-derived exosomes selectively impair lymphocyte responses to interleukin-2. Cancer Res (2007) 3.07
Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles. J Exp Med (2002) 3.02
Microenvironmental pH is a key factor for exosome traffic in tumor cells. J Biol Chem (2009) 2.99
Trans-synaptic transmission of vesicular Wnt signals through Evi/Wntless. Cell (2009) 2.91
Exosome release of β-catenin: a novel mechanism that antagonizes Wnt signaling. J Cell Biol (2010) 2.85
Active Wnt proteins are secreted on exosomes. Nat Cell Biol (2012) 2.81
Exosome release is regulated by a calcium-dependent mechanism in K562 cells. J Biol Chem (2003) 2.71
Human tumor-released microvesicles promote the differentiation of myeloid cells with transforming growth factor-beta-mediated suppressive activity on T lymphocytes. Cancer Res (2006) 2.61
Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells. Mol Cancer (2011) 2.56
Human tumor-derived exosomes down-modulate NKG2D expression. J Immunol (2008) 2.53
Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C. J Cell Biol (2010) 2.52
HIV-1 trafficking to the dendritic cell-T-cell infectious synapse uses a pathway of tetraspanin sorting to the immunological synapse. Traffic (2005) 2.47
Characterization and comprehensive proteome profiling of exosomes secreted by hepatocytes. J Proteome Res (2008) 2.41
ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming. Blood (2005) 2.34
Immature dendritic cell-derived exosomes can mediate HIV-1 trans infection. Proc Natl Acad Sci U S A (2006) 2.31
Packaging of prions into exosomes is associated with a novel pathway of PrP processing. J Pathol (2007) 2.31
Exosomes from human CD34(+) stem cells mediate their proangiogenic paracrine activity. Circ Res (2011) 2.31
Higher-order oligomerization targets plasma membrane proteins and HIV gag to exosomes. PLoS Biol (2007) 2.30
A lumenal domain-dependent pathway for sorting to intralumenal vesicles of multivesicular endosomes involved in organelle morphogenesis. Dev Cell (2006) 2.29
Regulation of signal transduction by endocytosis. Curr Opin Cell Biol (2000) 2.28
Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis. J Cell Sci (2011) 2.25
Cellular internalization of exosomes occurs through phagocytosis. Traffic (2010) 2.21
Release of exosomes from differentiated neurons and its regulation by synaptic glutamatergic activity. Mol Cell Neurosci (2010) 2.17
Fusion of lysosomes with late endosomes produces a hybrid organelle of intermediate density and is NSF dependent. J Cell Biol (1998) 2.12
Retracted Pregnancy-associated exosomes and their modulation of T cell signaling. J Immunol (2006) 2.00
Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: role in immune escape. Gastroenterology (2005) 2.00
MHC II in dendritic cells is targeted to lysosomes or T cell-induced exosomes via distinct multivesicular body pathways. Traffic (2009) 1.98
Release of full-length 55-kDa TNF receptor 1 in exosome-like vesicles: a mechanism for generation of soluble cytokine receptors. Proc Natl Acad Sci U S A (2004) 1.98
Astrocytes and Glioblastoma cells release exosomes carrying mtDNA. J Neural Transm (Vienna) (2009) 1.97
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Mol Cell Proteomics (2010) 1.97
Exosomes released from infected macrophages contain Mycobacterium avium glycopeptidolipids and are proinflammatory. J Biol Chem (2007) 1.96
Tumor-derived microvesicles induce, expand and up-regulate biological activities of human regulatory T cells (Treg). PLoS One (2010) 1.94
Amphiregulin exosomes increase cancer cell invasion. Curr Biol (2011) 1.93
Rab11 promotes docking and fusion of multivesicular bodies in a calcium-dependent manner. Traffic (2005) 1.92
A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44. Biochem J (2006) 1.92
Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. J Immunol (2003) 1.86
Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells. BMC Genomics (2009) 1.84
Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins. J Lipid Res (2010) 1.82
Aggregation reroutes molecules from a recycling to a vesicle-mediated secretion pathway during reticulocyte maturation. J Cell Sci (1997) 1.80
T-cell apoptosis and suppression of T-cell receptor/CD3-zeta by Fas ligand-containing membrane vesicles shed from ovarian tumors. Clin Cancer Res (2003) 1.79
Acid sphingomyelinase activity triggers microparticle release from glial cells. EMBO J (2009) 1.78
Exosome lipidomics unravels lipid sorting at the level of multivesicular bodies. Biochimie (2006) 1.78
Exosomes as a short-range mechanism to spread alloantigen between dendritic cells during T cell allorecognition. J Immunol (2008) 1.77
TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways. Biochim Biophys Acta (2009) 1.76
TSAP6 facilitates the secretion of translationally controlled tumor protein/histamine-releasing factor via a nonclassical pathway. J Biol Chem (2004) 1.72
Activated T cells recruit exosomes secreted by dendritic cells via LFA-1. Blood (2008) 1.71
Paracrine induction of endothelium by tumor exosomes. Lab Invest (2009) 1.63
Lysobisphosphatidic acid controls endosomal cholesterol levels. J Biol Chem (2008) 1.62
Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice. Cell Death Differ (2008) 1.58
Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? Proteomics Clin Appl (2007) 1.58
Capture and transfer of HIV-1 particles by mature dendritic cells converges with the exosome-dissemination pathway. Blood (2008) 1.58
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Mol Cell Proteomics (2012) 1.55
Inhibition of gamma-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes. FASEB J (2008) 1.52
CD8+ dendritic cells use LFA-1 to capture MHC-peptide complexes from exosomes in vivo. J Immunol (2007) 1.49
T cell-induced secretion of MHC class II-peptide complexes on B cell exosomes. EMBO J (2007) 1.47
Multiple roles of the vesicular-SNARE TI-VAMP in post-Golgi and endosomal trafficking. FEBS Lett (2009) 1.40
Direct exosome stimulation of peripheral human T cells detected by ELISPOT. Eur J Immunol (2006) 1.40
Alkalizing drugs induce accumulation of amyloid precursor protein by-products in luminal vesicles of multivesicular bodies. J Biol Chem (2007) 1.35
Mechanism of evenness interrupted (Evi)-exosome release at synaptic boutons. J Biol Chem (2012) 1.32
Exosome secretion of dendritic cells is regulated by Hrs, an ESCRT-0 protein. Biochem Biophys Res Commun (2010) 1.32
C2C12 myoblasts release micro-vesicles containing mtDNA and proteins involved in signal transduction. Exp Cell Res (2010) 1.30