Published in J Proteome Res on December 01, 2008
Membrane vesicles as conveyors of immune responses. Nat Rev Immunol (2009) 14.72
Extracellular vesicles: exosomes, microvesicles, and friends. J Cell Biol (2013) 10.02
MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins. Nat Cell Biol (2011) 8.21
Biological properties of extracellular vesicles and their physiological functions. J Extracell Vesicles (2015) 3.02
As we wait: coping with an imperfect nomenclature for extracellular vesicles. J Extracell Vesicles (2013) 3.01
Exosome-mediated transmission of hepatitis C virus between human hepatoma Huh7.5 cells. Proc Natl Acad Sci U S A (2013) 2.99
Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C. J Cell Biol (2010) 2.52
Microvesicles and viral infection. J Virol (2011) 2.10
Proteomics analysis of bladder cancer exosomes. Mol Cell Proteomics (2010) 2.04
Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription. Exp Hematol (2010) 2.01
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Mol Cell Proteomics (2010) 1.97
Proteomic analysis of urine exosomes reveals renal tubule response to leptospiral colonization in experimentally infected rats. PLoS Negl Trop Dis (2015) 1.92
Biliary exosomes influence cholangiocyte regulatory mechanisms and proliferation through interaction with primary cilia. Am J Physiol Gastrointest Liver Physiol (2010) 1.85
Extracellular heat shock proteins, cellular export vesicles, and the Stress Observation System: a form of communication during injury, infection, and cell damage. It is never known how far a controversial finding will go! Dedicated to Ferruccio Ritossa. Cell Stress Chaperones (2010) 1.69
Exosomes: small vesicles with big roles in hepatocellular carcinoma. Oncotarget (2016) 1.43
Circulating extracellular vesicles with specific proteome and liver microRNAs are potential biomarkers for liver injury in experimental fatty liver disease. PLoS One (2014) 1.31
MicroRNAs transported by exosomes in body fluids as mediators of intercellular communication in cancer. Onco Targets Ther (2014) 1.22
Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples. Proteomics Clin Appl (2010) 1.21
Exosomes in the pathogenesis, diagnostics and therapeutics of liver diseases. J Hepatol (2013) 1.12
Exosomes: novel biomarkers for clinical diagnosis. ScientificWorldJournal (2015) 1.11
Microvesicles derived from human umbilical cord Wharton's jelly mesenchymal stem cells attenuate bladder tumor cell growth in vitro and in vivo. PLoS One (2013) 1.09
Lipid-induced toxicity stimulates hepatocytes to release angiogenic microparticles that require Vanin-1 for uptake by endothelial cells. Sci Signal (2013) 1.08
Proteomic analysis of microvesicles released by the human prostate cancer cell line PC-3. Mol Cell Proteomics (2012) 1.08
Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate. J Hepatol (2015) 1.04
Signaling pathways in exosomes biogenesis, secretion and fate. Genes (Basel) (2013) 1.04
Physiology of cholangiocytes. Compr Physiol (2013) 1.00
Advances in the proteomic investigation of the cell secretome. Expert Rev Proteomics (2012) 1.00
Extracellular vesicles as modulators of cell-to-cell communication in the healthy and diseased brain. Philos Trans R Soc Lond B Biol Sci (2014) 0.99
Focus on Extracellular Vesicles: Introducing the Next Small Big Thing. Int J Mol Sci (2016) 0.96
Soluble serum CD81 is elevated in patients with chronic hepatitis C and correlates with alanine aminotransferase serum activity. PLoS One (2012) 0.95
MicroRNAs as Biomarkers for Liver Disease and Hepatocellular Carcinoma. Int J Mol Sci (2016) 0.93
Quantitative proteomic analysis of hepatocyte-secreted extracellular vesicles reveals candidate markers for liver toxicity. J Proteomics (2014) 0.93
Extracellular Vesicles Exploit Viral Entry Routes for Cargo Delivery. Microbiol Mol Biol Rev (2016) 0.91
Overview of extracellular microvesicles in drug metabolism. Expert Opin Drug Metab Toxicol (2010) 0.91
Transcriptome of extracellular vesicles released by hepatocytes. PLoS One (2013) 0.90
Human semen contains exosomes with potent anti-HIV-1 activity. Retrovirology (2014) 0.89
Characterization of endocytic compartments after holo-high density lipoprotein particle uptake in HepG2 cells. Histochem Cell Biol (2009) 0.88
Exosomes participate in the alteration of muscle homeostasis during lipid-induced insulin resistance in mice. Diabetologia (2014) 0.87
Exosomal Proteome Profiling: A Potential Multi-Marker Cellular Phenotyping Tool to Characterize Hypoxia-Induced Radiation Resistance in Breast Cancer. Proteomes (2013) 0.86
Isolation of extracellular vesicles: Determining the correct approach (Review). Int J Mol Med (2015) 0.85
Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells. Proteomics (2012) 0.84
The Dual Role of Exosomes in Hepatitis A and C Virus Transmission and Viral Immune Activation. Viruses (2015) 0.83
Exosomes are unlikely involved in intercellular Nef transfer. PLoS One (2015) 0.83
Liver extracellular vesicles in health and disease. J Extracell Vesicles (2012) 0.83
Secreted Oral Epithelial Cell Membrane Vesicles Induce Epstein-Barr Virus Reactivation in Latently Infected B Cells. J Virol (2016) 0.82
Exosomes and nanotubes: Control of immune cell communication. Int J Biochem Cell Biol (2015) 0.82
Analysis of exosome release as a cellular response to MAPK pathway inhibition. Langmuir (2015) 0.82
Preclinical evaluation of an anti-HCV miRNA cluster for treatment of HCV infection. Mol Ther (2013) 0.81
Tissue-specific gene silencing monitored in circulating RNA. RNA (2013) 0.81
A Comparative Study of Serum Exosome Isolation Using Differential Ultracentrifugation and Three Commercial Reagents. PLoS One (2017) 0.80
Considerations for applying metabolomics to the analysis of extracellular vesicles. Front Immunol (2014) 0.80
Combined treatment with a pH-sensitive fusogenic peptide and cationic lipids achieves enhanced cytosolic delivery of exosomes. Sci Rep (2015) 0.80
Exosomes in Human Immunodeficiency Virus Type I Pathogenesis: Threat or Opportunity? Adv Virol (2016) 0.80
Vectorization of biomacromolecules into cells using extracellular vesicles with enhanced internalization induced by macropinocytosis. Sci Rep (2016) 0.79
Subtoxic Alterations in Hepatocyte-Derived Exosomes: An Early Step in Drug-Induced Liver Injury? Toxicol Sci (2016) 0.79
Label-free Proteomic Analysis of Exosomes Derived from Inducible Hepatitis B Virus-Replicating HepAD38 Cell Line. Mol Cell Proteomics (2017) 0.79
Chemokine Receptors, CXCR1 and CXCR2, Differentially Regulate Exosome Release in Hepatocytes. PLoS One (2016) 0.77
Microvesicles as a potential biomarker of neoplastic diseases and their role in development and progression of neoplasm. Prz Menopauzalny (2015) 0.76
Human mammospheres secrete hormone-regulated active extracellular vesicles. PLoS One (2014) 0.76
Exosomes as miRNA Carriers: Formation-Function-Future. Int J Mol Sci (2016) 0.76
Exosomes as the source of biomarkers of metabolic diseases. Ann Pediatr Endocrinol Metab (2016) 0.76
Urine Proteome Biomarkers in Kidney Diseases. I. Limits, Perspectives, and First Focus on Normal Urine. Biomark Insights (2016) 0.76
On-chip immunoelectrophoresis of extracellular vesicles released from human breast cancer cells. PLoS One (2015) 0.76
Study of Exosomes Shed New Light on Physiology of Amyloidogenesis. Cell Mol Neurobiol (2016) 0.76
Organophosphate neurotoxicity to the voluntary motor system on the trail of environment-caused amyotrophic lateral sclerosis: the known, the misknown, and the unknown. Arch Toxicol (2017) 0.75
Comparative study of (18) F-FDG-PET/CT imaging and serum hTERT mRNA quantification in cancer diagnosis. Cancer Med (2015) 0.75
Increased liver-specific proteins in circulating extracellular vesicles as potential biomarkers for drug- and alcohol-induced liver injury. PLoS One (2017) 0.75
Exosome Proteome of U-87MG Glioblastoma Cells. Biology (Basel) (2016) 0.75
A Novel Sensitive Method to Measure Catechol-O-Methyltransferase Activity Unravels the Presence of This Activity in Extracellular Vesicles Released by Rat Hepatocytes. Front Pharmacol (2016) 0.75
Hepatocyte-secreted extracellular vesicles modify blood metabolome and endothelial function by an arginase-dependent mechanism. Sci Rep (2017) 0.75
Mast Cell-Derived Exosomes Promote Th2 Cell Differentiation via OX40L-OX40 Ligation. J Immunol Res (2016) 0.75
Paracrine Signaling by Extracellular Vesicles via Osteoblasts. Curr Mol Biol Rep (2016) 0.75
Liquid Biopsy in Non-Small Cell Lung Cancer. Front Med (Lausanne) (2016) 0.75
Functions of Exosomes and Microbial Extracellular Vesicles in Allergy and Contact and Delayed-Type Hypersensitivity. Int Arch Allergy Immunol (2016) 0.75
Comparative transcriptomic analysis of human and Drosophila extracellular vesicles. Sci Rep (2016) 0.75
Release of extracellular vesicles containing small RNAs from the eggs of Schistosoma japonicum. Parasit Vectors (2016) 0.75
Microvesicles released from fat-laden cells promote activation of hepatocellular NLRP3 inflammasome: A pro-inflammatory link between lipotoxicity and non-alcoholic steatohepatitis. PLoS One (2017) 0.75
Progress in Exosome Isolation Techniques. Theranostics (2017) 0.75
GPC1 exosome and its regulatory miRNAs are specific markers for the detection and target therapy of colorectal cancer. J Cell Mol Med (2017) 0.75
Effect of age on pro-inflammatory miRNAs contained in mesenchymal stem cell-derived extracellular vesicles. Sci Rep (2017) 0.75
Arginine-rich cell-penetrating peptide-modified extracellular vesicles for active macropinocytosis induction and efficient intracellular delivery. Sci Rep (2017) 0.75
Exosomes genetic cargo in lung cancer: a truly Pandora's box. Transl Lung Cancer Res (2016) 0.75
Insights into the Diagnostic Potential of Extracellular Vesicles and Their miRNA Signature from Liquid Biopsy as Early Biomarkers of Diabetic Micro/Macrovascular Complications. Int J Mol Sci (2017) 0.75
Size Exclusion HPLC Detection of Small-Size Impurities as a Complementary Means for Quality Analysis of Extracellular Vesicles. J Circ Biomark (2015) 0.75
Extracellular vesicles in liver disease and potential as biomarkers and therapeutic targets. Nat Rev Gastroenterol Hepatol (2017) 0.75
Creating the gene ontology resource: design and implementation. Genome Res (2001) 55.73
On the origin of cancer cells. Science (1956) 49.55
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol (2007) 37.10
Exosomes: composition, biogenesis and function. Nat Rev Immunol (2002) 13.99
B lymphocytes secrete antigen-presenting vesicles. J Exp Med (1996) 11.53
Ceramide triggers budding of exosome vesicles into multivesicular endosomes. Science (2008) 9.42
Identification and proteomic profiling of exosomes in human urine. Proc Natl Acad Sci U S A (2004) 8.74
GOLGI APPARATUS AND LYSOSOMES. Fed Proc (1965) 6.42
Exosomal-like vesicles are present in human blood plasma. Int Immunol (2005) 6.04
Exosomes: a common pathway for a specialized function. J Biochem (2006) 5.79
Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Nat Med (2001) 5.71
Exosomes: endosomal-derived vesicles shipping extracellular messages. Curr Opin Cell Biol (2004) 5.71
Cells release prions in association with exosomes. Proc Natl Acad Sci U S A (2004) 5.17
Malignant effusions and immunogenic tumour-derived exosomes. Lancet (2002) 4.91
Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73. J Cell Biol (1999) 4.87
Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor. Cell (1983) 4.55
Oncogenic alterations of metabolism. Trends Biochem Sci (1999) 4.51
Exosome function: from tumor immunology to pathogen biology. Traffic (2008) 4.50
The biogenesis and functions of exosomes. Traffic (2002) 4.49
Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes. J Exp Med (1991) 4.15
Alzheimer's disease beta-amyloid peptides are released in association with exosomes. Proc Natl Acad Sci U S A (2006) 3.98
Clinical importance of the cytochromes P450. Lancet (2002) 3.77
Intestinal epithelial cells secrete exosome-like vesicles. Gastroenterology (2001) 3.33
TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. J Immunol (2002) 3.28
Exosomes are released by cultured cortical neurones. Mol Cell Neurosci (2006) 3.07
Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles. J Exp Med (2002) 3.02
CD24 is a marker of exosomes secreted into urine and amniotic fluid. Kidney Int (2007) 3.01
Accumulation of major histocompatibility complex class II molecules in mast cell secretory granules and their release upon degranulation. Mol Biol Cell (1997) 2.78
Production and characterization of clinical grade exosomes derived from dendritic cells. J Immunol Methods (2002) 2.77
Human extrahepatic cytochromes P450: function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts. Annu Rev Pharmacol Toxicol (2002) 2.74
Late endosome motility depends on lipids via the small GTPase Rab7. EMBO J (2002) 2.68
Proteomic analysis of exosomes isolated from human malignant pleural effusions. Am J Respir Cell Mol Biol (2004) 2.44
BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes. Mol Biol Cell (2006) 2.37
Induction of heat shock proteins in B-cell exosomes. J Cell Sci (2005) 2.21
Proteomic analysis of exosomes secreted by human mesothelioma cells. Am J Pathol (2004) 2.13
Platelet-derived exosomes of septic individuals possess proapoptotic NAD(P)H oxidase activity: A novel vascular redox pathway. Crit Care Med (2004) 2.04
Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism. J Immunol (2005) 1.98
Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid. Eur Respir J (2003) 1.97
Exosomes released from infected macrophages contain Mycobacterium avium glycopeptidolipids and are proinflammatory. J Biol Chem (2007) 1.96
BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules. J Biol Chem (2002) 1.86
Hepatic uptake of chylomicron remnants. J Lipid Res (1997) 1.78
The asialoglycoprotein receptor: a model for endocytic transport receptors. Biochemistry (1990) 1.78
TfR2 localizes in lipid raft domains and is released in exosomes to activate signal transduction along the MAPK pathway. J Cell Sci (2006) 1.55
Cleavage of L1 in exosomes and apoptotic membrane vesicles released from ovarian carcinoma cells. Clin Cancer Res (2005) 1.54
A bioartificial liver--state of the art. Science (2002) 1.53
Retracted Identification and characterization of microvesicles secreted by 3T3-L1 adipocytes: redox- and hormone-dependent induction of milk fat globule-epidermal growth factor 8-associated microvesicles. Endocrinology (2007) 1.52
Association of hepatitis C virus envelope proteins with exosomes. Eur J Immunol (2004) 1.51
Identification, proteomic profiling, and origin of ram epididymal fluid exosome-like vesicles. Biol Reprod (2005) 1.51
Intestinal epithelial exosomes carry MHC class II/peptides able to inform the immune system in mice. Gut (2003) 1.44
The tyrosine kinase receptors Ron and Sea control "scattering" and morphogenesis of liver progenitor cells in vitro. Mol Biol Cell (1996) 1.42
Expression and function of cytochrome p450 in brain drug metabolism. Curr Drug Metab (2007) 1.36
Alkalizing drugs induce accumulation of amyloid precursor protein by-products in luminal vesicles of multivesicular bodies. J Biol Chem (2007) 1.35
Human hepatocytes in primary culture: the choice to investigate drug metabolism in man. Curr Drug Metab (2004) 1.22
Zinc transporter 2 (SLC30A2) can suppress the vesicular zinc defect of adaptor protein 3-depleted fibroblasts by promoting zinc accumulation in lysosomes. Exp Cell Res (2007) 1.20
Structure-function relationships in apolipoprotein(a): insights into lipoprotein(a) assembly and pathogenicity. Curr Opin Lipidol (2004) 1.20
Activation of NF-kappaB is essential for hepatocyte growth factor-mediated proliferation and tubulogenesis. Mol Cell Biol (2002) 1.18
Exosomes bearing HLA-G are released by melanoma cells. Hum Immunol (2003) 1.12
Cellular prion protein is released on exosomes from activated platelets. Blood (2006) 1.09
Revisiting the road to the discovery of exosomes. Blood Cells Mol Dis (2005) 1.05
Preparation of human ovarian cancer ascites-derived exosomes for a clinical trial. Blood Cells Mol Dis (2005) 1.04
The recycling of apolipoprotein E in primary cultures of mouse hepatocytes. Evidence for a physiologic connection to high density lipoprotein metabolism. J Biol Chem (2003) 1.00
A recycling pathway for resecretion of internalized apolipoprotein E in liver cells. J Biol Chem (2001) 0.99
Identification of a gene-pathway associated with non-alcoholic steatohepatitis. J Hepatol (2006) 0.97
The synthesis of apoproteins of very low density lipoproteins isolated from the Golgi apparatus of rat liver. Can J Biochem (1976) 0.97
Intracellular processing of endocytosed triglyceride-rich lipoproteins comprises both recycling and degradation. J Cell Sci (1999) 0.90
Disentangling conformational states of macromolecules in 3D-EM through likelihood optimization. Nat Methods (2006) 5.73
Dynamic reorganization of the functionally active ribosome explored by normal mode analysis and cryo-electron microscopy. Proc Natl Acad Sci U S A (2003) 3.64
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. PLoS Biol (2012) 3.18
Study of the structural dynamics of the E coli 70S ribosome using real-space refinement. Cell (2003) 3.03
Maximum-likelihood multi-reference refinement for electron microscopy images. J Mol Biol (2005) 3.00
Melanesian and Asian origins of Polynesians: mtDNA and Y chromosome gradients across the Pacific. Mol Biol Evol (2006) 2.98
Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice. Hepatology (2008) 2.91
Structure of ratcheted ribosomes with tRNAs in hybrid states. Proc Natl Acad Sci U S A (2008) 2.77
A cryo-electron microscopic study of ribosome-bound termination factor RF2. Nature (2003) 2.42
Role of S-adenosyl-L-methionine in liver health and injury. Hepatology (2007) 2.21
Emerging role of epigenetics in the actions of alcohol. Alcohol Clin Exp Res (2008) 2.14
Quaternary structures of tumor suppressor p53 and a specific p53 DNA complex. Proc Natl Acad Sci U S A (2007) 2.09
S-Adenosylmethionine: a control switch that regulates liver function. FASEB J (2002) 2.08
Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A. FASEB J (2002) 2.04
Methionine metabolism and liver disease. Annu Rev Nutr (2008) 1.98
MicroRNAs regulate methionine adenosyltransferase 1A expression in hepatocellular carcinoma. J Clin Invest (2012) 1.86
Fast maximum-likelihood refinement of electron microscopy images. Bioinformatics (2005) 1.83
Quantitative proteomic analysis of post-translational modifications of human histones. Mol Cell Proteomics (2006) 1.73
Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation. Hepatology (2012) 1.66
S-adenosylmethionine stabilizes cystathionine beta-synthase and modulates redox capacity. Proc Natl Acad Sci U S A (2006) 1.66
A new strategy for identification of N-glycosylated proteins and unambiguous assignment of their glycosylation sites using HILIC enrichment and partial deglycosylation. J Proteome Res (2004) 1.65
Epithelial-to-mesenchymal transition of murine liver tumor cells promotes invasion. Hepatology (2010) 1.63
Structure of the connector of bacteriophage T7 at 8A resolution: structural homologies of a basic component of a DNA translocating machinery. J Mol Biol (2005) 1.63
Nrf1 and Nrf2 regulate rat glutamate-cysteine ligase catalytic subunit transcription indirectly via NF-kappaB and AP-1. Mol Cell Biol (2005) 1.61
Averaging of electron subtomograms and random conical tilt reconstructions through likelihood optimization. Structure (2009) 1.59
Mechanism for the disassembly of the posttermination complex inferred from cryo-EM studies. Mol Cell (2005) 1.58
Comprehensive comparison of collision induced dissociation and electron transfer dissociation. Anal Chem (2008) 1.58
Role of methionine adenosyltransferase 2A and S-adenosylmethionine in mitogen-induced growth of human colon cancer cells. Gastroenterology (2007) 1.56
The role of tRNA as a molecular spring in decoding, accommodation, and peptidyl transfer. FEBS Lett (2005) 1.52
Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: summary of a symposium. Am J Clin Nutr (2007) 1.49
Non-alcoholic steatohepatitis and animal models: understanding the human disease. Int J Biochem Cell Biol (2008) 1.49
Sirtuin 1 regulation of developmental genes during differentiation of stem cells. Proc Natl Acad Sci U S A (2010) 1.48
Dynamics of EF-G interaction with the ribosome explored by classification of a heterogeneous cryo-EM dataset. J Struct Biol (2004) 1.46
S-adenosylmethionine regulates cytoplasmic HuR via AMP-activated kinase. Gastroenterology (2006) 1.44
GARBAN: genomic analysis and rapid biological annotation of cDNA microarray and proteomic data. Bioinformatics (2003) 1.43
Flexible fitting in 3D-EM guided by the structural variability of protein superfamilies. Structure (2006) 1.41
CD133+ liver cancer stem cells from methionine adenosyl transferase 1A-deficient mice demonstrate resistance to transforming growth factor (TGF)-beta-induced apoptosis. Hepatology (2009) 1.40
Stable isotope labeling of Arabidopsis thaliana cells and quantitative proteomics by mass spectrometry. Mol Cell Proteomics (2005) 1.39
Abnormal hepatic methionine and glutathione metabolism in patients with alcoholic hepatitis. Alcohol Clin Exp Res (2004) 1.37
The Cryo-EM structure of a complete 30S translation initiation complex from Escherichia coli. PLoS Biol (2011) 1.35
Functional proteomics of nonalcoholic steatohepatitis: mitochondrial proteins as targets of S-adenosylmethionine. Proc Natl Acad Sci U S A (2003) 1.35
Leptin's mitogenic effect in human liver cancer cells requires induction of both methionine adenosyltransferase 2A and 2beta. Hepatology (2008) 1.33
Expression pattern, regulation, and functions of methionine adenosyltransferase 2beta splicing variants in hepatoma cells. Gastroenterology (2007) 1.30
S-adenosylmethionine inhibits lipopolysaccharide-induced gene expression via modulation of histone methylation. Hepatology (2008) 1.30
Large T antigen on the simian virus 40 origin of replication: a 3D snapshot prior to DNA replication. EMBO J (2003) 1.30
S-adenosylmethionine and its metabolite induce apoptosis in HepG2 cells: Role of protein phosphatase 1 and Bcl-x(S). Hepatology (2004) 1.30
Liquid chromatography-mass spectrometry-based parallel metabolic profiling of human and mouse model serum reveals putative biomarkers associated with the progression of nonalcoholic fatty liver disease. J Proteome Res (2010) 1.29
L-methionine availability regulates expression of the methionine adenosyltransferase 2A gene in human hepatocarcinoma cells: role of S-adenosylmethionine. J Biol Chem (2003) 1.29
Expansion of liver cancer stem cells during aging in methionine adenosyltransferase 1A-deficient mice. Hepatology (2008) 1.27
Betaine prevents Mallory-Denk body formation in drug-primed mice by epigenetic mechanisms. Exp Mol Pathol (2008) 1.27
A symmetrical tetramer for S. aureus pyruvate carboxylase in complex with coenzyme A. Structure (2009) 1.26
Tumour necrosis factor alpha induces co-ordinated activation of rat GSH synthetic enzymes via nuclear factor kappaB and activator protein-1. Biochem J (2005) 1.24
S-adenosylmethionine and methylthioadenosine are antiapoptotic in cultured rat hepatocytes but proapoptotic in human hepatoma cells. Hepatology (2002) 1.24
5'-methylthioadenosine modulates the inflammatory response to endotoxin in mice and in rat hepatocytes. Hepatology (2004) 1.22
Methylthioadenosine. Int J Biochem Cell Biol (2004) 1.22
Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples. Proteomics Clin Appl (2010) 1.21
Dysregulation of glutathione synthesis during cholestasis in mice: molecular mechanisms and therapeutic implications. Hepatology (2009) 1.20
Changes in S-adenosylmethionine and GSH homeostasis during endotoxemia in mice. Lab Invest (2008) 1.19
Impaired liver regeneration in mice lacking methionine adenosyltransferase 1A. FASEB J (2004) 1.19
Alcohol, cofactors and the genetics of hepatocellular carcinoma. J Gastroenterol Hepatol (2008) 1.19
Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice. Hepatology (2010) 1.19
Cloning and characterization of the human glutathione synthetase 5'-flanking region. Biochem J (2005) 1.15
Alcohol, DNA methylation, and cancer. Alcohol Res (2013) 1.14
Annotation-Modules: a tool for finding significant combinations of multisource annotations for gene lists. Bioinformatics (2008) 1.14
Inhibition of lipopolysaccharide-stimulated TNF-alpha promoter activity by S-adenosylmethionine and 5'-methylthioadenosine. Am J Physiol Gastrointest Liver Physiol (2004) 1.14
Induction of human methionine adenosyltransferase 2A expression by tumor necrosis factor alpha. Role of NF-kappa B and AP-1. J Biol Chem (2003) 1.14
Inhibition of human betaine-homocysteine methyltransferase expression by S-adenosylmethionine and methylthioadenosine. Biochem J (2007) 1.14
Changes in the expression of methionine adenosyltransferase genes and S-adenosylmethionine homeostasis during hepatic stellate cell activation. Hepatology (2010) 1.13
Switch from Mnt-Max to Myc-Max induces p53 and cyclin D1 expression and apoptosis during cholestasis in mouse and human hepatocytes. Hepatology (2009) 1.12
Evidence for LKB1/AMP-activated protein kinase/ endothelial nitric oxide synthase cascade regulated by hepatocyte growth factor, S-adenosylmethionine, and nitric oxide in hepatocyte proliferation. Hepatology (2009) 1.11
Genetic polymorphisms in the methylenetetrahydrofolate reductase and thymidylate synthase genes and risk of hepatocellular carcinoma. Hepatology (2007) 1.08
Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNA. Proc Natl Acad Sci U S A (2010) 1.08
Reconstitution of proapoptotic BAK function in liposomes reveals a dual role for mitochondrial lipids in the BAK-driven membrane permeabilization process. J Biol Chem (2011) 1.08
Human spermatogenic failure purges deleterious mutation load from the autosomes and both sex chromosomes, including the gene DMRT1. PLoS Genet (2013) 1.08
Binding of S-methyl-5'-thioadenosine and S-adenosyl-L-methionine to protein MJ0100 triggers an open-to-closed conformational change in its CBS motif pair. J Mol Biol (2009) 1.07
An enzymatic deglycosylation scheme enabling identification of core fucosylated N-glycans and O-glycosylation site mapping of human plasma proteins. J Proteome Res (2007) 1.07
Forced expression of methionine adenosyltransferase 1A in human hepatoma cells suppresses in vivo tumorigenicity in mice. Am J Pathol (2010) 1.06
MAT2B-GIT1 interplay activates MEK1/ERK 1 and 2 to induce growth in human liver and colon cancer. Hepatology (2013) 1.06
Retinoid X receptor alpha regulates glutathione homeostasis and xenobiotic detoxification processes in mouse liver. Mol Pharmacol (2004) 1.05
HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis. Gastroenterology (2010) 1.04