Published in PLoS One on April 04, 2014
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Matriptase and prostasin are expressed in human skin in an inverse trend over the course of differentiation and are targeted to different regions of the plasma membrane. Biol Open (2016) 0.76
Natural Endogenous Human Matriptase and Prostasin Undergo Zymogen Activation via Independent Mechanisms in an Uncoupled Manner. PLoS One (2016) 0.75
Matriptase shedding is closely coupled with matriptase zymogen activation and requires de novo proteolytic cleavage likely involving its own activity. PLoS One (2017) 0.75
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Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins. Nature (1998) 15.09
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The activation of matriptase requires its noncatalytic domains, serine protease domain, and its cognate inhibitor. J Biol Chem (2003) 1.71
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Molecular cloning of cDNA for matriptase, a matrix-degrading serine protease with trypsin-like activity. J Biol Chem (1999) 1.62
Noninvasive measurement of the pH of the endoplasmic reticulum at rest and during calcium release. Proc Natl Acad Sci U S A (1998) 1.59
HAI-1 regulates activation and expression of matriptase, a membrane-bound serine protease. Am J Physiol Cell Physiol (2005) 1.56
Autosomal recessive ichthyosis with hypotrichosis caused by a mutation in ST14, encoding type II transmembrane serine protease matriptase. Am J Hum Genet (2007) 1.56
Activation of epithelial sodium channels by mouse channel activating proteases (mCAP) expressed in Xenopus oocytes requires catalytic activity of mCAP3 and mCAP2 but not mCAP1. J Am Soc Nephrol (2006) 1.48
Autosomal ichthyosis with hypotrichosis syndrome displays low matriptase proteolytic activity and is phenocopied in ST14 hypomorphic mice. J Biol Chem (2007) 1.44
Initiation of plasminogen activation on the surface of monocytes expressing the type II transmembrane serine protease matriptase. Blood (2006) 1.36
Characterization of a novel, membrane-bound, 80-kDa matrix-degrading protease from human breast cancer cells. Monoclonal antibody production, isolation, and localization. J Biol Chem (1997) 1.36
Simultaneous activation and hepatocyte growth factor activator inhibitor 1-mediated inhibition of matriptase induced at activation foci in human mammary epithelial cells. Am J Physiol Cell Physiol (2004) 1.29
Autoactivation of matriptase in vitro: requirement for biomembrane and LDL receptor domain. Am J Physiol Cell Physiol (2007) 1.27
Matriptase activation, an early cellular response to acidosis. J Biol Chem (2009) 1.24
Autocatalytic activation of human cathepsin K. J Biol Chem (1997) 1.20
Regulation of the matriptase-prostasin cell surface proteolytic cascade by hepatocyte growth factor activator inhibitor-1 during epidermal differentiation. J Biol Chem (2010) 1.19
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Mechanism of activation of the gastric aspartic proteinases: pepsinogen, progastricsin and prochymosin. Biochem J (1998) 1.14
Mutation G827R in matriptase causing autosomal recessive ichthyosis with hypotrichosis yields an inactive protease. J Biol Chem (2008) 1.01
Assembly of adherens junctions is required for sphingosine 1-phosphate-induced matriptase accumulation and activation at mammary epithelial cell-cell contacts. Am J Physiol Cell Physiol (2004) 0.98
The optimal activity of a pseudozymogen form of recombinant matriptase under the mildly acidic pH and low ionic strength conditions. J Biochem (2009) 0.93
Mechanisms for the control of matriptase activity in the absence of sufficient HAI-1. Am J Physiol Cell Physiol (2011) 0.92
Antithrombin regulates matriptase activity involved in plasmin generation, syndecan shedding, and HGF activation in keratinocytes. PLoS One (2013) 0.92
Proteolytic cleavage of human acid-sensing ion channel 1 by the serine protease matriptase. J Biol Chem (2010) 0.91
Oxidative stress in a phenylketonuria animal model. Free Radic Biol Med (2002) 0.86
Protons and Ca2+: ionic allies in tumor progression? Physiology (Bethesda) (2011) 0.85
Matriptase regulates proliferation and early, but not terminal, differentiation of human keratinocytes. J Invest Dermatol (2013) 0.84
Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade. J Med Chem (2011) 0.84
Imbalanced matriptase pericellular proteolysis contributes to the pathogenesis of malignant B-cell lymphomas. Am J Pathol (2013) 0.83
Matriptase regulates proliferation and early, but not terminal, differentiation of human keratinocytes. J Invest Dermatol (2013) 0.84
Matriptase Complexes and Prostasin Complexes with HAI-1 and HAI-2 in Human Milk: Significant Proteolysis in Lactation. PLoS One (2016) 0.84
Natural Endogenous Human Matriptase and Prostasin Undergo Zymogen Activation via Independent Mechanisms in an Uncoupled Manner. PLoS One (2016) 0.75
Selective Inhibition of Prostasin in Human Enterocytes by the Integral Membrane Kunitz-Type Serine Protease Inhibitor HAI-2. PLoS One (2017) 0.75