The pH of the secretory pathway: measurement, determinants, and regulation.

PubWeight™: 2.16‹?› | Rank: Top 2%

🔗 View Article (PMID 15304635)

Published in Physiology (Bethesda) on August 01, 2004

Authors

Paul Paroutis1, Nicolas Touret, Sergio Grinstein

Author Affiliations

1: Cell Biology Program, Hospital for Sick Children, Toronto M5G 1X8 Ontario, Canada.

Articles citing this

(truncated to the top 100)

Sensors and regulators of intracellular pH. Nat Rev Mol Cell Biol (2009) 4.30

The where, when, and how of organelle acidification by the yeast vacuolar H+-ATPase. Microbiol Mol Biol Rev (2006) 2.79

The yeast lysosome-like vacuole: endpoint and crossroads. Biochim Biophys Acta (2008) 2.22

Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery. AAPS J (2009) 1.68

A pH-regulated quality control cycle for surveillance of secretory protein assembly. Mol Cell (2013) 1.60

Functional architecture of Weibel-Palade bodies. Blood (2011) 1.55

A novel mode of TRPML3 regulation by extracytosolic pH absent in the varitint-waddler phenotype. EMBO J (2008) 1.47

The Erv41-Erv46 complex serves as a retrograde receptor to retrieve escaped ER proteins. J Cell Biol (2015) 1.46

The long physiological reach of the yeast vacuolar H+-ATPase. J Bioenerg Biomembr (2007) 1.36

Rate, extent and concentration dependence of histamine-evoked Weibel-Palade body exocytosis determined from individual fusion events in human endothelial cells. J Physiol (2007) 1.36

Vesicles versus Tubes: Is Endoplasmic Reticulum-Golgi Transport in Plants Fundamentally Different from Other Eukaryotes? Plant Physiol (2015) 1.22

Identification of Pseudomonas aeruginosa phenazines that kill Caenorhabditis elegans. PLoS Pathog (2013) 1.20

Fluorescent proteins in cellular organelles: serious pitfalls and some solutions. DNA Cell Biol (2013) 1.19

A revised model for the secretion of tPA and cytokines from cultured endothelial cells. Blood (2010) 1.14

Participation of endomembrane cation/H+ exchanger AtCHX20 in osmoregulation of guard cells. Plant Physiol (2007) 1.12

Genes required for osmoregulation and apical secretion in Caenorhabditis elegans. Genetics (2006) 1.12

The calcium channel mucolipin-3 is a novel regulator of trafficking along the endosomal pathway. Traffic (2009) 1.12

Function of the anion transporter AtCLC-d in the trans-Golgi network. Plant J (2007) 1.11

Sorting of GPI-anchored proteins into ER exit sites by p24 proteins is dependent on remodeled GPI. J Cell Biol (2011) 1.06

Intracellular BK(Ca) (iBK(Ca)) channels. J Physiol (2012) 1.05

In vitro and in vivo studies identify important features of dengue virus pr-E protein interactions. PLoS Pathog (2010) 1.02

In vivo crystallization of human IgG in the endoplasmic reticulum of engineered Chinese hamster ovary (CHO) cells. J Biol Chem (2011) 1.00

In vivo intracellular pH measurements in tobacco and Arabidopsis reveal an unexpected pH gradient in the endomembrane system. Plant Cell (2013) 0.99

Lectin domains of polypeptide GalNAc transferases exhibit glycopeptide binding specificity. J Biol Chem (2011) 0.98

Structural determinants of integrin β-subunit specificity for latent TGF-β. Nat Struct Mol Biol (2014) 0.97

Organelle redox of CF and CFTR-corrected airway epithelia. Free Radic Biol Med (2007) 0.97

The function of the intermediate compartment in pre-Golgi trafficking involves its stable connection with the centrosome. Mol Biol Cell (2009) 0.96

Cellular mechanisms of alpha herpesvirus egress: live cell fluorescence microscopy of pseudorabies virus exocytosis. PLoS Pathog (2014) 0.95

The association of hepatitis C virus glycoproteins with apolipoproteins E and B early in assembly is conserved in lipoviral particles. J Biol Chem (2014) 0.93

Hepatitis C virus p7-a viroporin crucial for virus assembly and an emerging target for antiviral therapy. Viruses (2010) 0.93

NHE8 is an intracellular cation/H+ exchanger in renal tubules of the yellow fever mosquito Aedes aegypti. Am J Physiol Renal Physiol (2009) 0.93

A palette of fluorescent proteins optimized for diverse cellular environments. Nat Commun (2015) 0.92

Aberrant Ca2+ handling in lysosomal storage disorders. Cell Calcium (2010) 0.91

pH Regulation by NHX-Type Antiporters Is Required for Receptor-Mediated Protein Trafficking to the Vacuole in Arabidopsis. Plant Cell (2015) 0.89

The Angelman syndrome protein Ube3a/E6AP is required for Golgi acidification and surface protein sialylation. J Neurosci (2013) 0.89

Clinical review: Renal tubular acidosis--a physicochemical approach. Crit Care (2005) 0.89

Protonation-dependent conformational variability of intrinsically disordered proteins. Protein Sci (2013) 0.89

Self-assembly of filamentous amelogenin requires calcium and phosphate: from dimers via nanoribbons to fibrils. Biomacromolecules (2012) 0.88

N-linked glycan at residue 523 of human parainfluenza virus type 3 hemagglutinin-neuraminidase masks a second receptor-binding site. J Virol (2010) 0.88

Multiple Transport Pathways for Mediating Intracellular pH Homeostasis: The Contribution of H(+)/ion Exchangers. Front Plant Sci (2012) 0.88

Nanoscale metal-organic frameworks for real-time intracellular pH sensing in live cells. J Am Chem Soc (2014) 0.86

A toggle switch controls the low pH-triggered rearrangement and maturation of the dengue virus envelope proteins. Nat Commun (2014) 0.86

Structural characterization of carbohydrate binding by LMAN1 protein provides new insight into the endoplasmic reticulum export of factors V (FV) and VIII (FVIII). J Biol Chem (2013) 0.85

Zinc transporters and their role in the pancreatic β-cell. J Diabetes Investig (2012) 0.85

Ca(2+) channels on the move. Biochemistry (2009) 0.85

V-ATPase-mediated granular acidification is regulated by the V-ATPase accessory subunit Ac45 in POMC-producing cells. Mol Biol Cell (2010) 0.84

General Strategy to Introduce pH-Induced Allostery in DNA-Based Receptors to Achieve Controlled Release of Ligands. Nano Lett (2015) 0.83

Aggregates, crystals, gels, and amyloids: intracellular and extracellular phenotypes at the crossroads of immunoglobulin physicochemical property and cell physiology. Int J Cell Biol (2013) 0.83

Fluorescent Protein Approaches in Alpha Herpesvirus Research. Viruses (2015) 0.82

Molecular dissection of Erv26p identifies separable cargo binding and coat protein sorting activities. J Biol Chem (2009) 0.82

Preferential apelin-13 production by the proprotein convertase PCSK3 is implicated in obesity. FEBS Open Bio (2013) 0.82

Reactive Self-Assembly of Polymers and Proteins to Reversibly Silence a Killer Protein. Biomacromolecules (2015) 0.82

Russell body phenotype is preferentially induced by IgG mAb clones with high intrinsic condensation propensity: relations between the biosynthetic events in the ER and solution behaviors in vitro. MAbs (2014) 0.81

Fluorogenic Green-Inside Red-Outside (GIRO) Labeling Approach Reveals Adenylyl Cyclase-Dependent Control of BKα Surface Expression. Bioconjug Chem (2015) 0.81

Proteoglycan synthesis and Golgi organization in polarized epithelial cells. J Histochem Cytochem (2012) 0.81

Developmental genetics of secretory vesicle acidification during Caenorhabditis elegans spermatogenesis. Genetics (2012) 0.81

The cyclooxygenase-2 inhibitor celecoxib is a potent inhibitor of human carbonic anhydrase II. Inflammation (2004) 0.81

Nanoparticle-Based and Bioengineered Probes and Sensors to Detect Physiological and Pathological Biomarkers in Neural Cells. Front Neurosci (2015) 0.81

Requirement of the activity of hepatocyte growth factor activator inhibitor type 1 for the extracellular appearance of a transmembrane serine protease matriptase in monkey kidney COS-1 cells. Cytotechnology (2009) 0.81

Amyloid-like aggregation of provasopressin in diabetes insipidus and secretory granule sorting. BMC Biol (2017) 0.80

Integrin engagement by the helical RGD motif of the Helicobacter pylori CagL protein is regulated by pH-induced displacement of a neighboring helix. J Biol Chem (2015) 0.80

Ca2+ induces spontaneous dephosphorylation of a novel P5A-type ATPase. J Biol Chem (2012) 0.80

An unusual organelle in Cryptococcus neoformans links luminal pH and capsule biosynthesis. Fungal Genet Biol (2009) 0.80

Identification of domains within the V-ATPase accessory subunit Ac45 involved in V-ATPase transport and Ca2+-dependent exocytosis. J Biol Chem (2012) 0.80

Förster resonance energy transfer-based sensor targeting endoplasmic reticulum reveals highly oxidative environment. Exp Biol Med (Maywood) (2012) 0.80

A key interaction between the alphavirus envelope proteins responsible for initial dimer dissociation during fusion. J Virol (2013) 0.80

Matriptase autoactivation is tightly regulated by the cellular chemical environments. PLoS One (2014) 0.80

Loss of vacuolar H+-ATPase activity in organelles signals ubiquitination and endocytosis of the yeast plasma membrane proton pump Pma1p. J Biol Chem (2014) 0.80

The Nicotine Metabolite, Cotinine, Alters the Assembly and Trafficking of a Subset of Nicotinic Acetylcholine Receptors. J Biol Chem (2015) 0.79

AtNHX5 and AtNHX6 Are Required for the Subcellular Localization of the SNARE Complex That Mediates the Trafficking of Seed Storage Proteins in Arabidopsis. PLoS One (2016) 0.79

The role of E3 in pH protection during alphavirus assembly and exit. J Virol (2013) 0.79

Human and viral Golgi anti-apoptotic proteins (GAAPs) oligomerize via different mechanisms and monomeric GAAP inhibits apoptosis and modulates calcium. J Biol Chem (2013) 0.79

Anilinomethylrhodamines: pH sensitive probes with tunable photophysical properties by substituent effect. J Org Chem (2013) 0.79

Inhibition of lysosome degradation on autophagosome formation and responses to GMI, an immunomodulatory protein from Ganoderma microsporum. Br J Pharmacol (2012) 0.79

Accommodation of large cargo within Golgi cisternae. Histochem Cell Biol (2013) 0.78

Entrapment in phospholipid vesicles quenches photoactivity of quantum dots. Int J Nanomedicine (2011) 0.78

Ethylene and plant responses to phosphate deficiency. Front Plant Sci (2015) 0.78

An examination of the proteolytic activity for bovine pregnancy-associated glycoproteins 2 and 12. Biol Chem (2010) 0.78

Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome. Virology (2015) 0.78

Abscission of flowers and floral organs is closely associated with alkalization of the cytosol in abscission zone cells. J Exp Bot (2014) 0.78

Transient Expression of Tetrameric Recombinant Human Butyrylcholinesterase in Nicotiana benthamiana. Front Plant Sci (2016) 0.78

The pH-dependent Client Release from the Collagen-specific Chaperone HSP47 Is Triggered by a Tandem Histidine Pair. J Biol Chem (2016) 0.77

p24 family proteins: key players in the regulation of trafficking along the secretory pathway. Protoplasma (2015) 0.77

Combined deficiency of coagulation factors V and VIII: an update. Semin Thromb Hemost (2013) 0.77

Quantitative analysis of autophagic flux by confocal pH-imaging of autophagic intermediates. Autophagy (2015) 0.77

An isoform of the vacuolar (H(+))-ATPase accessory subunit Ac45. Cell Mol Life Sci (2009) 0.77

pH-regulated metal-ligand switching in the HM loop of ATP7A: a new paradigm for metal transfer chemistry. Metallomics (2016) 0.76

Mechanism of Fine-tuning pH Sensors in Proprotein Convertases: IDENTIFICATION OF A pH-SENSING HISTIDINE PAIR IN THE PROPEPTIDE OF PROPROTEIN CONVERTASE 1/3. J Biol Chem (2015) 0.76

Actin Filaments Are Involved in the Coupling of V0-V1 Domains of Vacuolar H+-ATPase at the Golgi Complex. J Biol Chem (2016) 0.75

Internalization and fusion mechanism of vesicular stomatitis virus and related rhabdoviruses. Future Virol (2010) 0.75

Nicotinic Acetylcholine Receptors as Targets for Tobacco Cessation Therapeutics: Cutting-Edge Methodologies to Understand Receptor Assembly and Trafficking. Neuromethods (2016) 0.75

Structural basis of pH-dependent client binding by ERp44, a key regulator of protein secretion at the ER-Golgi interface. Proc Natl Acad Sci U S A (2017) 0.75

Alkaline Cytosolic pH and High Sodium Hydrogen Exchanger 1 (NHE1) Activity in Th9 Cells. J Biol Chem (2016) 0.75

Characterization of Drosophila CMP-sialic acid synthetase activity reveals unusual enzymatic properties. Biochem J (2016) 0.75

Glucosylceramide Reorganizes Cholesterol-Containing Domains in a Fluid Phospholipid Membrane. Biophys J (2016) 0.75

Single-cell intracellular nano-pH probes. RSC Adv (2015) 0.75

Photobleaching methods to study Golgi complex dynamics in living cells. Methods Cell Biol (2013) 0.75

Intermolecular interactions involving an acidic patch on immunoglobulin variable domain and the γ2 constant region mediate crystalline inclusion body formation in the endoplasmic reticulum. Cell Logist (2017) 0.75

Selective and regulated trapping of nicotinic receptor weak base ligands and relevance to smoking cessation. Elife (2017) 0.75

Inwardly rectifying potassium channels regulate Dpp release in the Drosophila wing disc. Development (2017) 0.75

Articles by these authors

Robust single-particle tracking in live-cell time-lapse sequences. Nat Methods (2008) 9.43

The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol (2006) 5.83

Membrane phosphatidylserine regulates surface charge and protein localization. Science (2008) 5.37

Sensors and regulators of intracellular pH. Nat Rev Mol Cell Biol (2009) 4.30

Activation of antibacterial autophagy by NADPH oxidases. Proc Natl Acad Sci U S A (2009) 3.87

Antimicrobial mechanisms of phagocytes and bacterial evasion strategies. Nat Rev Microbiol (2009) 3.83

Phagosome maturation: aging gracefully. Biochem J (2002) 3.42

The distribution and function of phosphatidylserine in cellular membranes. Annu Rev Biophys (2010) 3.31

In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity (2010) 3.19

LAMP proteins are required for fusion of lysosomes with phagosomes. EMBO J (2007) 2.97

Diversity of the mammalian sodium/proton exchanger SLC9 gene family. Pflugers Arch (2003) 2.89

The cell biology of phagocytosis. Annu Rev Pathol (2011) 2.71

Receptor activation alters inner surface potential during phagocytosis. Science (2006) 2.69

Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling. J Cell Biol (2010) 2.65

Cytoskeletal control of CD36 diffusion promotes its receptor and signaling function. Cell (2011) 2.57

Phagocytosis and innate immunity. Curr Opin Immunol (2002) 2.47

Quantitative and dynamic assessment of the contribution of the ER to phagosome formation. Cell (2005) 2.35

Phagosomes fuse with late endosomes and/or lysosomes by extension of membrane protrusions along microtubules: role of Rab7 and RILP. Mol Cell Biol (2003) 2.33

Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase. Mol Cell Biol (2003) 2.03

The phosphoinositide-binding protein p40phox activates the NADPH oxidase during FcgammaIIA receptor-induced phagocytosis. J Exp Med (2006) 2.03

A cation counterflux supports lysosomal acidification. J Cell Biol (2010) 2.02

Regulation of endocytosis via the oxygen-sensing pathway. Nat Med (2009) 2.00

Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis. J Cell Biol (2005) 1.81

Scavenger receptors in homeostasis and immunity. Nat Rev Immunol (2013) 1.77

Elimination of host cell PtdIns(4,5)P(2) by bacterial SigD promotes membrane fission during invasion by Salmonella. Nat Cell Biol (2002) 1.75

The ESAT-6/CFP-10 secretion system of Mycobacterium marinum modulates phagosome maturation. Cell Microbiol (2006) 1.72

Phagocytosis by neutrophils. Microbes Infect (2003) 1.65

The nature of the phagosomal membrane: endoplasmic reticulum versus plasmalemma. J Leukoc Biol (2005) 1.65

SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34. J Cell Biol (2008) 1.64

Salmonella impairs RILP recruitment to Rab7 during maturation of invasion vacuoles. Mol Biol Cell (2004) 1.56

A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium. J Cell Biol (2007) 1.52

Lipid signaling and the modulation of surface charge during phagocytosis. Immunol Rev (2007) 1.51

Regulation of vacuolar pH and its modulation by some microbial species. Microbiol Mol Biol Rev (2007) 1.49

High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine. J Cell Biol (2011) 1.49

Listeriolysin O suppresses phospholipase C-mediated activation of the microbicidal NADPH oxidase to promote Listeria monocytogenes infection. Cell Host Microbe (2011) 1.48

Salmonella redirects phagosomal maturation. Curr Opin Microbiol (2004) 1.48

Unconventional roles of the NADPH oxidase: signaling, ion homeostasis, and cell death. Sci STKE (2007) 1.44

In situ measurement of the electrical potential across the phagosomal membrane using FRET and its contribution to the proton-motive force. Proc Natl Acad Sci U S A (2007) 1.40

Contribution of phosphatidylserine to membrane surface charge and protein targeting during phagosome maturation. J Cell Biol (2009) 1.38

The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosis. Mol Biol Cell (2014) 1.38

Visualization of vacuolar acidification-induced transcription of genes of pathogens inside macrophages. Mol Biol Cell (2005) 1.37

Contrasting requirements for ubiquitylation during Fc receptor-mediated endocytosis and phagocytosis. EMBO J (2002) 1.36

Intracellular survival of Burkholderia cenocepacia in macrophages is associated with a delay in the maturation of bacteria-containing vacuoles. Cell Microbiol (2006) 1.35

Inhibition of phosphatidylinositol-4-phosphate 5-kinase Ialpha impairs localized actin remodeling and suppresses phagocytosis. J Biol Chem (2002) 1.35

How nascent phagosomes mature to become phagolysosomes. Trends Immunol (2012) 1.34

Lipid metabolism and dynamics during phagocytosis. Curr Opin Cell Biol (2006) 1.32

Phosphatidylserine is polarized and required for proper Cdc42 localization and for development of cell polarity. Nat Cell Biol (2011) 1.31

Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36. Nature (2013) 1.30

Critical role for scaffolding adapter Gab2 in Fc gamma R-mediated phagocytosis. J Cell Biol (2003) 1.28

Fc gamma R-stimulated activation of the NADPH oxidase: phosphoinositide-binding protein p40phox regulates NADPH oxidase activity after enzyme assembly on the phagosome. Blood (2008) 1.27

Differential role of actin, clathrin, and dynamin in Fc gamma receptor-mediated endocytosis and phagocytosis. J Biol Chem (2002) 1.27

Lysosomal calcium homeostasis defects, not proton pump defects, cause endo-lysosomal dysfunction in PSEN-deficient cells. J Cell Biol (2012) 1.24

Role of 3-phosphoinositides in the maturation of Salmonella-containing vacuoles within host cells. J Biol Chem (2002) 1.23

Determinants of the phagosomal pH in neutrophils. J Biol Chem (2001) 1.23

Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase activity. J Biol Chem (2004) 1.22

The phosphoinositide phosphatase SopB manipulates membrane surface charge and trafficking of the Salmonella-containing vacuole. Cell Host Microbe (2010) 1.20

Rho GTPases dictate the mobility of the Na/H exchanger NHE3 in epithelia: role in apical retention and targeting. Proc Natl Acad Sci U S A (2005) 1.20

Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria. Mol Cell Biol (2004) 1.20

Emerging roles of alkali cation/proton exchangers in organellar homeostasis. Curr Opin Cell Biol (2007) 1.20

Role of phospholipids in endocytosis, phagocytosis, and macropinocytosis. Physiol Rev (2013) 1.19

Bruton's Tyrosine Kinase (BTK) and Vav1 contribute to Dectin1-dependent phagocytosis of Candida albicans in macrophages. PLoS Pathog (2013) 1.19

Mammalian septins are required for phagosome formation. Mol Biol Cell (2008) 1.16

The role of the C terminus and Na+/H+ exchanger regulatory factor in the functional expression of cystic fibrosis transmembrane conductance regulator in nonpolarized cells and epithelia. J Biol Chem (2003) 1.16

Nramp1 modifies the fusion of Salmonella typhimurium-containing vacuoles with cellular endomembranes in macrophages. J Biol Chem (2001) 1.15

Inhibition and redistribution of NHE3, the apical Na+/H+ exchanger, by Clostridium difficile toxin B. J Gen Physiol (2004) 1.15

Syntaxins 13 and 7 function at distinct steps during phagocytosis. J Immunol (2002) 1.13

Coronin-1 function is required for phagosome formation. Mol Biol Cell (2005) 1.12

Fcgamma-receptors induce Mac-1 (CD11b/CD18) mobilization and accumulation in the phagocytic cup for optimal phagocytosis. J Biol Chem (2003) 1.11

Fusion, fission, and secretion during phagocytosis. Physiology (Bethesda) (2007) 1.11

Pathogen destruction versus intracellular survival: the role of lipids as phagosomal fate determinants. J Clin Invest (2008) 1.10

Phosphatidylserine dynamics in cellular membranes. Mol Biol Cell (2012) 1.10

Altered lipid droplet dynamics in hepatocytes lacking triacylglycerol hydrolase expression. Mol Biol Cell (2010) 1.09

Phosphatidylinositol 3-kinases in carcinoembryonic antigen-related cellular adhesion molecule-mediated internalization of Neisseria gonorrhoeae. J Biol Chem (2003) 1.09

Evidence for a fence that impedes the diffusion of phosphatidylinositol 4,5-bisphosphate out of the forming phagosomes of macrophages. Mol Biol Cell (2011) 1.09

Restriction of Legionella pneumophila replication in macrophages requires concerted action of the transcriptional regulators Irf1 and Irf8 and nod-like receptors Naip5 and Nlrc4. Infect Immun (2009) 1.08

An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis. J Cell Biol (2009) 1.08

Alteration of epithelial structure and function associated with PtdIns(4,5)P2 degradation by a bacterial phosphatase. J Gen Physiol (2007) 1.07

Phagocytosis and the microtubule cytoskeleton. Biochem Cell Biol (2002) 1.07

Sorting nexin 3 (SNX3) is a component of a tubular endosomal network induced by Salmonella and involved in maturation of the Salmonella-containing vacuole. Cell Microbiol (2010) 1.07

Dynamic macrophage "probing" is required for the efficient capture of phagocytic targets. J Cell Biol (2010) 1.06

Dynamic traffic through the recycling compartment couples the metal transporter Nramp2 (DMT1) with the transferrin receptor. J Biol Chem (2003) 1.06

Expression and subcellular localization of NRAMP1 in human neutrophil granules. Blood (2002) 1.05

CD36 and TLR interactions in inflammation and phagocytosis: implications for malaria. J Immunol (2009) 1.05

Uptake of oxidized low density lipoprotein by CD36 occurs by an actin-dependent pathway distinct from macropinocytosis. J Biol Chem (2009) 1.04

Multimolecular signaling complexes enable Syk-mediated signaling of CD36 internalization. Dev Cell (2013) 1.04

Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling. Mol Biol Cell (2011) 1.03

Enteropathogenic Escherichia coli subverts phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate upon epithelial cell infection. Mol Biol Cell (2008) 1.03

CD44 is a phagocytic receptor. Blood (2006) 1.03

Cholesterol accumulation by macrophages impairs phagosome maturation. J Biol Chem (2008) 1.02

Carboxyl-terminus determinants of the iron transporter DMT1/SLC11A2 isoform II (-IRE/1B) mediate internalization from the plasma membrane into recycling endosomes. Biochemistry (2005) 1.02

Localized exocytosis of primary (lysosomal) granules during phagocytosis: role of Ca2+-dependent tyrosine phosphorylation and microtubules. J Immunol (2002) 1.02

Subversion of phagocytosis for pathogen survival. Cell Host Microbe (2012) 1.02

Role of ubiquitin and proteasomes in phagosome maturation. Mol Biol Cell (2005) 1.01

Golgi-bound Rab34 is a novel member of the secretory pathway. Mol Biol Cell (2007) 1.01