Published in J Clin Endocrinol Metab on July 01, 1989
Two-subunit structure of the human thyrotropin receptor. Proc Natl Acad Sci U S A (1992) 1.26
Cloning from the thyroid of a protein related to actin binding protein that is recognized by Graves disease immunoglobulins. Proc Natl Acad Sci U S A (1993) 0.83
Direct evidence that ganglioside is an integral component of the thyrotropin receptor. Proc Natl Acad Sci U S A (1991) 0.75
Latent autoimmune diabetes in adults (LADA) should be less latent. Diabetologia (2005) 4.87
High-level semi-synthetic production of the potent antimalarial artemisinin. Nature (2013) 3.80
Linkage disequilibrium of a type 1 diabetes susceptibility locus with a regulatory IL12B allele. Nat Genet (2001) 2.54
Diabetes in transgenic mice resulting from over-expression of class I histocompatibility molecules in pancreatic beta cells. Nature (1988) 2.46
A randomized trial of high-dose vitamin D2 in relapsing-remitting multiple sclerosis. Neurology (2011) 2.39
Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice. Diabetes (1997) 2.19
Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice. J Clin Invest (1991) 2.07
MHCPEP, a database of MHC-binding peptides: update 1997. Nucleic Acids Res (1998) 2.02
IFN-gamma and tumor necrosis factor-alpha. Cytotoxicity to murine islets of Langerhans. J Immunol (1988) 1.83
Biosynthetic labeling of insulin receptor: studies of subunits in cultured human IM-9 lymphocytes. Proc Natl Acad Sci U S A (1981) 1.72
Insulin receptors, receptor antibodies, and the mechanism of insulin action. Recent Prog Horm Res (1981) 1.68
INS(GFP/w) human embryonic stem cells facilitate isolation of in vitro derived insulin-producing cells. Diabetologia (2011) 1.68
Association between rotavirus infection and pancreatic islet autoimmunity in children at risk of developing type 1 diabetes. Diabetes (2000) 1.67
Insulin resistance is a risk factor for progression to type 1 diabetes. Diabetologia (2004) 1.64
Diurnal rhythms of pro-inflammatory cytokines: regulation by plasma cortisol and therapeutic implications. Cytokine (1998) 1.63
SPAK, a STE20/SPS1-related kinase that activates the p38 pathway. Oncogene (2000) 1.59
Purification of the insulin receptor from human placenta by chromatography on immobilized wheat germ lectin and receptor antibody. J Biol Chem (1980) 1.54
Immune characterization of an individual with an exceptionally high natural killer T cell frequency and her immediate family. Clin Exp Immunol (2009) 1.52
Neural network-based prediction of candidate T-cell epitopes. Nat Biotechnol (1998) 1.49
Autoantibodies to beta 2-adrenergic receptors: a possible cause of adrenergic hyporesponsiveness in allergic rhinitis and asthma. Science (1980) 1.48
The chronobiology of human cytokine production. Int Rev Immunol (1998) 1.47
Isoprenoid biosynthesis in plants: carbon partitioning within the cytoplasmic pathway. Crit Rev Biochem Mol Biol (1999) 1.47
Binding of insulin receptors to lectins: evidence for common carbohydrate determinants on several membrane receptors. Biochemistry (1981) 1.45
MHCPEP: a database of MHC-binding peptides. Nucleic Acids Res (1994) 1.41
Correlation between insulin receptor binding in isolated fat cells and insulin sensitivity in obese human subjects. J Clin Invest (1976) 1.40
Immunotherapy in pre-type 1 diabetes mellitus. Diabetologia (1990) 1.39
Extreme insulin resistance in ataxia telangiectasia: defect in affinity of insulin receptors. N Engl J Med (1978) 1.37
Intercellular adhesion molecule 1 is induced on isolated endocrine islet cells by cytokines but not by reovirus infection. Proc Natl Acad Sci U S A (1989) 1.32
Similar peptides from two beta cell autoantigens, proinsulin and glutamic acid decarboxylase, stimulate T cells of individuals at risk for insulin-dependent diabetes. Mol Med (1995) 1.28
Subunit structure of the insulin receptor of the human lymphocyte. Biochemistry (1980) 1.25
Evidence that a peptide spanning the B-C junction of proinsulin is an early Autoantigen epitope in the pathogenesis of type 1 diabetes. J Immunol (2001) 1.23
Diurnal rhythmicity of human cytokine production: a dynamic disequilibrium in T helper cell type 1/T helper cell type 2 balance? J Immunol (1997) 1.23
Evidence for IL-6 production by and effects on the pancreatic beta-cell. J Immunol (1989) 1.20
Immunoprecipitation of the insulin receptor: a sensitive assay for receptor antibodies and a specific technique for receptor purification. J Clin Endocrinol Metab (1979) 1.20
Islet autoimmunity in infants with a Type I diabetic relative is common but is frequently restricted to one autoantibody. Diabetologia (2000) 1.20
Thyrotrophin (TSH) binding sites on Yersinia enterocolitica recognized by immunoglobulins from humans with Graves' disease. Clin Exp Immunol (1986) 1.18
Autoantibodies against the insulin receptor recognize the insulin binding subunits of an oligomeric receptor. Diabetes (1981) 1.18
T-cell epitopes in type 1 diabetes autoantigen tyrosine phosphatase IA-2: potential for mimicry with rotavirus and other environmental agents. Mol Med (1998) 1.17
The effect of solubilization on the properties of the insulin receptor of human placental membranes. Endocrinology (1978) 1.15
Double-blind controlled trial of azathioprine in children with newly diagnosed type I diabetes. Diabetes (1989) 1.14
Glutamic acid decarboxylase 67-reactive T cells: a marker of insulin-dependent diabetes. J Exp Med (1993) 1.13
Impaired yield, phenotype, and function of monocyte-derived dendritic cells in humans at risk for insulin-dependent diabetes. J Immunol (1998) 1.13
Increase in remission rate in newly diagnosed type I diabetic subjects treated with azathioprine. Diabetes (1985) 1.13
Auditory cortex of squirrel monkey: response patterns of single cells to species-specific vocalizations. Science (1972) 1.12
Overview: the major histocompatibility complex and insulin dependent diabetes mellitus. Baillieres Clin Endocrinol Metab (1991) 1.11
Regulation of insulin receptors in normal and abnormal physiology in humans. Adv Intern Med (1979) 1.10
Analysis of families at risk for insulin-dependent diabetes mellitus reveals that HLA antigens influence progression to clinical disease. Mol Med (1995) 1.10
Direct evidence for the expression of multiple endogenous retroviruses in the synovial compartment in rheumatoid arthritis. Arthritis Rheum (1997) 1.08
MHCPEP, a database of MHC-binding peptides: update 1996. Nucleic Acids Res (1997) 1.07
HLA antigens and age at diagnosis of insulin-dependent diabetes mellitus. Hum Immunol (1995) 1.07
Multiple coding of species-specific vocalizations in the auditory cortex of squirrel monkeys. Brain Res (1973) 1.06
The human placenta contains two distinct binding and immunoreactive species of insulin-like growth factor-I receptors. J Biol Chem (1985) 1.06
Markers on distal chromosome 2q linked to insulin-dependent diabetes mellitus. Science (1996) 1.06
Lack of association between duration of breast-feeding or introduction of cow's milk and development of islet autoimmunity. Diabetes (1999) 1.06
Interferon-gamma enhances the expression of the major histocompatibility class I antigens on mouse pancreatic beta cells. Diabetes (1985) 1.06
Insulin binding leads to the formation of covalent (-S-S-) hormone receptor complexes. J Biol Chem (1982) 1.04
Laminin-1 promotes differentiation of fetal mouse pancreatic beta-cells. Diabetes (1999) 1.04
IFN-gamma induces islet cell MHC antigens and enhances autoimmune, streptozotocin-induced diabetes in the mouse. J Immunol (1988) 1.04
The potential roles of endogenous retroviruses in autoimmunity. Immunol Rev (1996) 1.04
Cloning and partial nucleotide sequence of human glutamic acid decarboxylase cDNA from brain and pancreatic islets. Biochem Biophys Res Commun (1991) 1.03
High level of concordance between assays for glutamic acid decarboxylase antibodies. The First International Glutamic Acid Decarboxylase Antibody Workshop. Diabetes (1994) 1.03
Molecular pathology of type 1 diabetes. Mol Biol Med (1990) 1.00
Anatomical and physiological evidence for a relationship between the 'cingular' vocalization area and the auditory cortex in the squirrel monkey. Brain Res (1980) 0.99
Regulation of MHC protein expression in pancreatic beta-cells by interferon-gamma and tumor necrosis factor-alpha. Mol Endocrinol (1988) 0.99
Cytokine-based human whole blood assay for the detection of antigen-reactive T cells. J Immunol Methods (1995) 0.98
Feasibility of using fMRI to study mothers responding to infant cries. Depress Anxiety (1999) 0.98
Heterogeneity of the insulin-receptor interaction in lipoatropic diabetes. J Clin Endocrinol Metab (1981) 0.97
Cytotoxic T cells to an epitope in the islet autoantigen IA-2 are not disease-specific. Clin Immunol (2001) 0.97
Reduction in insulitis following administration of IFN-gamma and TNF-alpha in the NOD mouse. J Autoimmun (1991) 0.97
Role of midline frontolimbic cortex in production of the isolation call of squirrel monkeys. Brain Res (1988) 0.97
Cu/Zn superoxide dismutase mRNA and enzyme activity, and susceptibility to lipid peroxidation, increases with aging in murine brains. Brain Res Mol Brain Res (1992) 0.96
Reovirus infection enhances expression of class I MHC proteins on human beta-cell and rat RINm5F cell. Diabetes (1988) 0.96
Retroviral superantigens and type 1 diabetes mellitus. Cell (1998) 0.96
Structural differences between insulin and somatomedin-C/insulin-like growth factor-1 receptors revealed by autoantibodies to the insulin receptor. Biochem Biophys Res Commun (1982) 0.96
T-cell antigen receptor transmembrane peptides modulate T-cell function and T cell-mediated disease. Nat Med (1997) 0.96
Glutamic acid decarboxylase autoantibodies in preclinical insulin-dependent diabetes. Proc Natl Acad Sci U S A (1992) 0.96
Localization and quantitation of expression of two glutamate decarboxylase genes in pancreatic beta-cells and other peripheral tissues of mouse and rat. Endocrinology (1993) 0.95
The beta cell in autoimmune diabetes: many mechanisms and pathways of loss. Trends Endocrinol Metab (2001) 0.94
Single unit analysis of auditory processing in squirrel monkey frontal cortex. Exp Brain Res (1976) 0.94
Mucosal antigen primes diabetogenic cytotoxic T-lymphocytes regardless of dose or delivery route. Diabetes (2001) 0.94
Report from the 1st International NOD Mouse T-Cell Workshop and the follow-up mini-workshop. Diabetes (2001) 0.94
Identification of pancreatic beta cell-related genes by representational difference analysis. Endocrinology (1997) 0.94
Fuzzy neural network-based prediction of the motif for MHC class II binding peptides. J Biosci Bioeng (2001) 0.94
IgG subclass antibodies to glutamic acid decarboxylase and risk for progression to clinical insulin-dependent diabetes. Hum Immunol (1998) 0.93
Evidence that macrophages are required for T-cell infiltration and rejection of fetal pig pancreas xenografts in nonobese diabetic mice. Transplantation (1998) 0.93
An atypical insulin receptor with high affinity for insulin-like growth factors copurified with placental insulin receptors. Proc Natl Acad Sci U S A (1986) 0.93
The A-chain of insulin is a hot-spot for CD4+ T cell epitopes in human type 1 diabetes. Clin Exp Immunol (2009) 0.93
Social context affects phee call production by nonreproductive common marmosets (Callithrix jacchus). Am J Primatol (1997) 0.93
Precipitation of the thyrotropin receptor and identification of thyroid autoantigens using Graves' disease immunoglobulins. J Clin Invest (1984) 0.93
Overexpression of class I major histocompatibility complex accompanies insulitis in the non-obese diabetic mouse and is prevented by anti-interferon-gamma antibody. Diabetologia (1991) 0.92
Antitopoisomerase I monoclonal autoantibodies from scleroderma patients and tight skin mouse interact with similar epitopes. J Exp Med (1992) 0.92
Innate and adaptive immune responses to nonvascular xenografts: evidence that macrophages are direct effectors of xenograft rejection. J Immunol (2001) 0.92
MHCPEP--a database of MHC-binding peptides: update 1995. Nucleic Acids Res (1996) 0.92
The Melbourne Pre-Diabetes Study: prediction of type 1 diabetes mellitus using antibody and metabolic testing. Med J Aust (1998) 0.92
Gamma delta T cells as mediators of mucosal tolerance: the autoimmune diabetes model. Immunol Rev (2000) 0.91
Novel strategy for identification of candidate cytotoxic T-cell epitopes from human preproinsulin. Tissue Antigens (2003) 0.90
Stabilization of glucose transporter mRNA by insulin/IGF-1 and glucose deprivation. Biochem Biophys Res Commun (1990) 0.90
Mapping of multiple B cell epitopes on the 70-kilodalton autoantigen of the U1 ribonucleoprotein complex. J Immunol (1990) 0.90
Disulfide exchange between insulin and its receptor. A possible post-binding step in insulin action. J Biol Chem (1983) 0.90