Published in BioData Min on April 11, 2014
CINOEDV: a co-information based method for detecting and visualizing n-order epistatic interactions. BMC Bioinformatics (2016) 0.79
A screening-testing approach for detecting gene-environment interactions using sequential penalized and unpenalized multiple logistic regression. Pac Symp Biocomput (2015) 0.78
Functional dyadicity and heterophilicity of gene-gene interactions in statistical epistasis networks. BioData Min (2015) 0.77
Studying the Genetics of Complex Disease With Ancestry-Specific Human Phenotype Networks: The Case of Type 2 Diabetes in East Asian Populations. Genet Epidemiol (2016) 0.75
Missing heritability and strategies for finding the underlying causes of complex disease. Nat Rev Genet (2010) 14.81
Detecting gene-gene interactions that underlie human diseases. Nat Rev Genet (2009) 12.07
Epistasis: too often neglected in complex trait studies? Nat Rev Genet (2004) 8.66
The ubiquitous nature of epistasis in determining susceptibility to common human diseases. Hum Hered (2003) 7.42
ToppGene Suite for gene list enrichment analysis and candidate gene prioritization. Nucleic Acids Res (2009) 7.34
A random variance model for detection of differential gene expression in small microarray experiments. Bioinformatics (2003) 6.31
A flexible computational framework for detecting, characterizing, and interpreting statistical patterns of epistasis in genetic studies of human disease susceptibility. J Theor Biol (2006) 6.22
A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. Nat Genet (2010) 3.93
The less harmful cigarette: a controversial issue. a tribute to Ernst L. Wynder. Chem Res Toxicol (2001) 3.59
Design of an epidemiologic study of drinking water arsenic exposure and skin and bladder cancer risk in a U.S. population. Environ Health Perspect (1998) 2.22
Characterizing genetic interactions in human disease association studies using statistical epistasis networks. BMC Bioinformatics (2011) 1.68
Comparison of normalization methods for Illumina BeadChip HumanHT-12 v3. BMC Genomics (2010) 1.50
"IARC group 2A Carcinogens" reported in cigarette mainstream smoke. Food Chem Toxicol (2000) 1.40
A genome-wide association study of bladder cancer identifies a new susceptibility locus within SLC14A1, a urea transporter gene on chromosome 18q12.3. Hum Mol Genet (2011) 1.36
DNA methylation as a long-term biomarker of exposure to tobacco smoke. Epidemiology (2013) 1.28
An information-gain approach to detecting three-way epistatic interactions in genetic association studies. J Am Med Inform Assoc (2013) 1.19
Entropy-based information gain approaches to detect and to characterize gene-gene and gene-environment interactions/correlations of complex diseases. Genet Epidemiol (2011) 1.16
ViSEN: methodology and software for visualization of statistical epistasis networks. Genet Epidemiol (2013) 0.93
"IARC group 2B Carcinogens" reported in cigarette mainstream smoke. Food Chem Toxicol (2000) 0.92
The effect of benzo(a)pyrene on porcine urinary bladder epithelial cells analyzed for the expression of selected genes and cellular toxicological endpoints. Toxicology (2005) 0.80
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLoS Genet (2009) 7.07
New common variants affecting susceptibility to basal cell carcinoma. Nat Genet (2009) 4.15
A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. Nat Genet (2010) 3.93
Model-based clustering of DNA methylation array data: a recursive-partitioning algorithm for high-dimensional data arising as a mixture of beta distributions. BMC Bioinformatics (2008) 3.89
Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors. Development (2003) 3.88
Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments. BMC Bioinformatics (2006) 3.39
Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium. J Natl Cancer Inst (2010) 3.18
MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors. J Clin Invest (2010) 2.87
DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma. J Natl Cancer Inst (2010) 2.87
Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression. Nat Genet (2012) 2.86
Upregulation of c-MYC in cis through a large chromatin loop linked to a cancer risk-associated single-nucleotide polymorphism in colorectal cancer cells. Mol Cell Biol (2010) 2.80
Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer. Nat Genet (2009) 2.76
Rice consumption and urinary arsenic concentrations in U.S. children. Environ Health Perspect (2012) 2.44
A case-control study of smoking and bladder cancer risk: emergent patterns over time. J Natl Cancer Inst (2009) 2.40
Arsenic, organic foods, and brown rice syrup. Environ Health Perspect (2012) 2.37
Sun exposure and melanoma risk at different latitudes: a pooled analysis of 5700 cases and 7216 controls. Int J Epidemiol (2009) 2.32
A core MYC gene expression signature is prominent in basal-like breast cancer but only partially overlaps the core serum response. PLoS One (2009) 2.29
A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolism. Mol Cell Biol (2002) 2.27
Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex. J Biol Chem (2009) 2.23
Implications of LINE1 methylation for bladder cancer risk in women. Clin Cancer Res (2010) 2.10
Concordance of multiple analytical approaches demonstrates a complex relationship between DNA repair gene SNPs, smoking and bladder cancer susceptibility. Carcinogenesis (2005) 2.08
Which fish should I eat? Perspectives influencing fish consumption choices. Environ Health Perspect (2012) 2.06
Rice consumption contributes to arsenic exposure in US women. Proc Natl Acad Sci U S A (2011) 2.03
Common genetic polymorphisms modify the effect of smoking on absolute risk of bladder cancer. Cancer Res (2013) 1.99
Epigenetic profiling reveals etiologically distinct patterns of DNA methylation in head and neck squamous cell carcinoma. Carcinogenesis (2009) 1.94
Selenium and colorectal adenoma: results of a pooled analysis. J Natl Cancer Inst (2004) 1.93
DNA methylation array analysis identifies profiles of blood-derived DNA methylation associated with bladder cancer. J Clin Oncol (2011) 1.92
Mechanism of transcriptional activation by the Myc oncoproteins. Semin Cancer Biol (2006) 1.91
TRRAP-dependent and TRRAP-independent transcriptional activation by Myc family oncoproteins. Mol Cell Biol (2002) 1.80
Blood-based profiles of DNA methylation predict the underlying distribution of cell types: a validation analysis. Epigenetics (2013) 1.79
Lung cancer in a U.S. population with low to moderate arsenic exposure. Environ Health Perspect (2009) 1.77
Peripheral blood immune cell methylation profiles are associated with nonhematopoietic cancers. Cancer Epidemiol Biomarkers Prev (2012) 1.76
The Myc transactivation domain promotes global phosphorylation of the RNA polymerase II carboxy-terminal domain independently of direct DNA binding. Mol Cell Biol (2007) 1.75
Retracted Nuclear receptor function requires a TFTC-type histone acetyl transferase complex. Mol Cell (2002) 1.75
Breast cancer DNA methylation profiles are associated with tumor size and alcohol and folate intake. PLoS Genet (2010) 1.74
Epigenetic profiles distinguish pleural mesothelioma from normal pleura and predict lung asbestos burden and clinical outcome. Cancer Res (2009) 1.73
BAF53 forms distinct nuclear complexes and functions as a critical c-Myc-interacting nuclear cofactor for oncogenic transformation. Mol Cell Biol (2002) 1.69
Ah receptor signals cross-talk with multiple developmental pathways. Biochem Pharmacol (2004) 1.69
Characterizing genetic interactions in human disease association studies using statistical epistasis networks. BMC Bioinformatics (2011) 1.68
Effect of calcium supplementation on the risk of large bowel polyps. J Natl Cancer Inst (2004) 1.67
Differential DNA methylation in umbilical cord blood of infants exposed to low levels of arsenic in utero. Environ Health Perspect (2013) 1.66
Photosensitizing agents and the risk of non-melanoma skin cancer: a population-based case-control study. J Invest Dermatol (2013) 1.65
Semi-supervised recursively partitioned mixture models for identifying cancer subtypes. Bioinformatics (2010) 1.63
A computationally efficient hypothesis testing method for epistasis analysis using multifactor dimensionality reduction. Genet Epidemiol (2009) 1.61
XRCC3 and XPD/ERCC2 single nucleotide polymorphisms and the risk of cancer: a HuGE review. Am J Epidemiol (2006) 1.58
Chronic diseases requiring hospitalization and risk of non-melanoma skin cancers--a population based study from Denmark. J Invest Dermatol (2007) 1.57
Ecogeographic genetic epidemiology. Genet Epidemiol (2009) 1.57
Carcinogen exposure and gene promoter hypermethylation in bladder cancer. Carcinogenesis (2005) 1.55
In utero and early life arsenic exposure in relation to long-term health and disease. Toxicol Appl Pharmacol (2013) 1.54
A pooled analysis of melanocytic nevus phenotype and the risk of cutaneous melanoma at different latitudes. Int J Cancer (2009) 1.51
International Lung Cancer Consortium: pooled analysis of sequence variants in DNA repair and cell cycle pathways. Cancer Epidemiol Biomarkers Prev (2008) 1.51
c-Myc transforms human mammary epithelial cells through repression of the Wnt inhibitors DKK1 and SFRP1. Mol Cell Biol (2007) 1.50
Gene-drug interaction at the glucocorticoid receptor increases risk of squamous cell skin cancer. J Invest Dermatol (2007) 1.47
A system-level pathway-phenotype association analysis using synthetic feature random forest. Genet Epidemiol (2014) 1.46
Myc protein is stabilized by suppression of a novel E3 ligase complex in cancer cells. Genes Dev (2010) 1.46
Bladder cancer SNP panel predicts susceptibility and survival. Hum Genet (2009) 1.43
Polymorphisms in DNA repair genes, smoking, and bladder cancer risk: findings from the international consortium of bladder cancer. Cancer Res (2009) 1.43
Arsenic exposure is associated with decreased DNA repair in vitro and in individuals exposed to drinking water arsenic. Environ Health Perspect (2006) 1.41
Epigenetic inactivation of SFRP genes and TP53 alteration act jointly as markers of invasive bladder cancer. Cancer Res (2005) 1.40
Occupation and bladder cancer in a population-based case-control study in Northern New England. Occup Environ Med (2010) 1.40
Promoter hypermethylation is associated with current smoking, age, gender and survival in bladder cancer. Carcinogenesis (2007) 1.40
Is the inverse association between selenium and bladder cancer due to confounding by smoking? Am J Epidemiol (2015) 1.39
Drinking-water arsenic exposure modulates gene expression in human lymphocytes from a U.S. population. Environ Health Perspect (2008) 1.39
Expression of genes in the TGF-beta signaling pathway is significantly deregulated in smooth muscle cells from aorta of aryl hydrocarbon receptor knockout mice. Toxicol Appl Pharmacol (2004) 1.37
A genome-wide association study of bladder cancer identifies a new susceptibility locus within SLC14A1, a urea transporter gene on chromosome 18q12.3. Hum Mol Genet (2011) 1.36
Common genetic variants in the PSCA gene influence gene expression and bladder cancer risk. Proc Natl Acad Sci U S A (2012) 1.36
Microarray results improve significantly as hybridization approaches equilibrium. Biotechniques (2004) 1.35
Genome-wide association study identifies multiple loci associated with bladder cancer risk. Hum Mol Genet (2013) 1.34
Survival following the diagnosis of noninvasive bladder cancer: WHO/International Society of Urological Pathology versus WHO classification systems. J Urol (2007) 1.33
Microsatellite instability at tetranucleotide repeats in skin and bladder cancer. Oncogene (2002) 1.33
Enabling personal genomics with an explicit test of epistasis. Pac Symp Biocomput (2010) 1.33
In utero arsenic exposure and infant infection in a United States cohort: a prospective study. Environ Res (2013) 1.31
Mapping of the UGT1A locus identifies an uncommon coding variant that affects mRNA expression and protects from bladder cancer. Hum Mol Genet (2012) 1.31
Ligand-independent regulation of transforming growth factor beta1 expression and cell cycle progression by the aryl hydrocarbon receptor. Mol Cell Biol (2007) 1.30
Decreased DNA repair gene expression among individuals exposed to arsenic in United States drinking water. Int J Cancer (2003) 1.29
Analgesic and anti-inflammatory drug use and risk of bladder cancer: a population based case control study. BMC Urol (2007) 1.28
Previous lung diseases and lung cancer risk: a pooled analysis from the International Lung Cancer Consortium. Am J Epidemiol (2012) 1.27
Identification of methylated genes associated with aggressive bladder cancer. PLoS One (2010) 1.27
Phosducin-like protein acts as a molecular chaperone for G protein betagamma dimer assembly. EMBO J (2005) 1.26
MicroRNAs and regeneration: Let-7 members as potential regulators of dedifferentiation in lens and inner ear hair cell regeneration of the adult newt. Biochem Biophys Res Commun (2007) 1.26
Evolution of the holozoan ribosome biogenesis regulon. BMC Genomics (2008) 1.25
The role of metallothionein in the pathogenesis of acute lung injury. Am J Respir Cell Mol Biol (2005) 1.25
Comparison of two expert-based assessments of diesel exhaust exposure in a case-control study: programmable decision rules versus expert review of individual jobs. Occup Environ Med (2012) 1.25
DNA repair polymorphisms modify bladder cancer risk: a multi-factor analytic strategy. Hum Hered (2007) 1.25
Normal neonatal microbiome variation in relation to environmental factors, infection and allergy. Curr Opin Pediatr (2012) 1.23
Nucleolin is required for RNA polymerase I transcription in vivo. Mol Cell Biol (2006) 1.23
Examination of a CpG island methylator phenotype and implications of methylation profiles in solid tumors. Cancer Res (2006) 1.23