Published in PLoS One on April 18, 2014
An amplified sensitivity arising from covalent modification in biological systems. Proc Natl Acad Sci U S A (1981) 10.04
Calcium oscillations increase the efficiency and specificity of gene expression. Nature (1998) 9.19
Nuclear hormone receptors and gene expression. Physiol Rev (2001) 4.56
Hypophysial responses to continuous and intermittent delivery of hypopthalamic gonadotropin-releasing hormone. Science (1978) 3.15
Encoding and decoding cellular information through signaling dynamics. Cell (2013) 2.96
Pulsatile insulin has greater hypoglycemic effect than continuous delivery. Diabetes (1983) 1.61
Frequency and amplitude of gonadotropin-releasing hormone stimulation and gonadotropin secretion in the rhesus monkey. Endocrinology (1981) 1.55
Optimizing release from peptide hormone secretory nerve terminals. J Exp Biol (1988) 1.46
The crucial role of pulsatile activity of the HPA axis for continuous dynamic equilibration. Nat Rev Neurosci (2010) 1.45
Diverse sensitivity thresholds in dynamic signaling responses by social amoebae. Sci Signal (2012) 1.41
Signaling by G-protein-coupled receptor (GPCR): studies on the GnRH receptor. Front Neuroendocrinol (2008) 1.40
Pulsatile portal vein insulin delivery enhances hepatic insulin action and signaling. Diabetes (2012) 1.32
Differential effects of gonadotropin-releasing hormone (GnRH) pulse frequency on gonadotropin subunit and GnRH receptor messenger ribonucleic acid levels in vitro. Endocrinology (1997) 1.32
The frequency of gonadotropin-releasing-hormone stimulation differentially regulates gonadotropin subunit messenger ribonucleic acid expression. Endocrinology (1989) 1.25
GnRH signaling, the gonadotrope and endocrine control of fertility. Front Neuroendocrinol (2010) 1.23
Control of the rhesus monkey menstrual cycle: permissive role of hypothalamic gonadotropin-releasing hormone. Science (1980) 1.19
Oxytocin secretion and human parturition: pulse frequency and duration increase during spontaneous labor in women. Am J Obstet Gynecol (1991) 1.04
Module dynamics of the GnRH signal transduction network. J Theor Biol (2002) 1.01
Negative feedback governs gonadotrope frequency-decoding of gonadotropin releasing hormone pulse-frequency. PLoS One (2009) 0.97
Hypothalamic dysfunction. Mol Cell Endocrinol (2001) 0.92
Signaling responses to pulsatile gonadotropin-releasing hormone in LbetaT2 gonadotrope cells. J Biol Chem (2010) 0.92
Pulsatile glucagon delivery enhances glucose production by perifused rat hepatocytes. Am J Physiol (1984) 0.91
GnRH pulse frequency-dependent stimulation of FSHβ transcription is mediated via activation of PKA and CREB. Mol Endocrinol (2013) 0.91
Estradiol induces both qualitative and quantitative changes in the pattern of gonadotropin-releasing hormone secretion during the presurge period in the ewe. Endocrinology (1995) 0.86
Decoding GnRH neurohormone pulse frequency by convergent signalling modules. J R Soc Interface (2011) 0.83
Glucose Oscillations Can Activate an Endogenous Oscillator in Pancreatic Islets. PLoS Comput Biol (2016) 0.77