TRPA1.

H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway. Nat Commun (2014) 1.16

Human TRPA1 is intrinsically cold- and chemosensitive with and without its N-terminal ankyrin repeat domain. Proc Natl Acad Sci U S A (2014) 1.07

TRPA1 channels: molecular sentinels of cellular stress and tissue damage. J Physiol (2016) 0.98

Targeting TRP channels for novel migraine therapeutics. ACS Chem Neurosci (2014) 0.87

ThermoTRPs and Pain. Neuroscientist (2015) 0.86

Species-specific temperature sensitivity of TRPA1. Temperature (Austin) (2015) 0.84

Acupuncture for visceral pain: neural substrates and potential mechanisms. Evid Based Complement Alternat Med (2014) 0.82

TRP channels in schistosomes. Int J Parasitol Drugs Drug Resist (2016) 0.82

TRPV1: A Target for Rational Drug Design. Pharmaceuticals (Basel) (2016) 0.82

Urate crystal induced inflammation and joint pain are reduced in transient receptor potential ankyrin 1 deficient mice--potential role for transient receptor potential ankyrin 1 in gout. PLoS One (2015) 0.81

Gustatory-mediated avoidance of bacterial lipopolysaccharides via TRPA1 activation in Drosophila. Elife (2016) 0.80

Human TRPA1 is a heat sensor displaying intrinsic U-shaped thermosensitivity. Sci Rep (2016) 0.79

Nociceptive TRP Channels: Sensory Detectors and Transducers in Multiple Pain Pathologies. Pharmaceuticals (Basel) (2016) 0.78

Transient receptor potential ankyrin 1 (TRPA1) is functionally expressed in primary human osteoarthritic chondrocytes. Arthritis Res Ther (2016) 0.78

TRP Channels in Respiratory Pathophysiology: the Role of Oxidative, Chemical Irritant and Temperature Stimuli. Curr Neuropharmacol (2015) 0.78

Differential Activation of TRP Channels in the Adult Rat Spinal Substantia Gelatinosa by Stereoisomers of Plant-Derived Chemicals. Pharmaceuticals (Basel) (2016) 0.78

Ingestion of TRP channel agonists attenuates exercise-induced muscle cramps. Muscle Nerve (2017) 0.77

Evidence for Novel Pharmacological Sensitivities of Transient Receptor Potential (TRP) Channels in Schistosoma mansoni. PLoS Negl Trop Dis (2015) 0.77

Streptozotocin Stimulates the Ion Channel TRPA1 Directly: INVOLVEMENT OF PEROXYNITRITE. J Biol Chem (2015) 0.77

Role of transient receptor potential ankyrin 1 channels in Alzheimer's disease. J Neuroinflammation (2016) 0.77

Phosphoinositide signaling in somatosensory neurons. Adv Biol Regul (2015) 0.76

Calmodulin is responsible for Ca(2+)-dependent regulation of TRPA1 Channels. Sci Rep (2017) 0.75

N-terminal tetrapeptide T/SPLH motifs contribute to multimodal activation of human TRPA1 channel. Sci Rep (2016) 0.75

The First Extracellular Linker Is Important for Several Aspects of the Gating Mechanism of Human TRPA1 Channel. Front Mol Neurosci (2017) 0.75

The N-terminal Ankyrin Repeat Domain Is Not Required for Electrophile and Heat Activation of the Purified Mosquito TRPA1 Receptor. J Biol Chem (2016) 0.75

TRPA1-FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p. Nat Commun (2017) 0.75

Hydrogen Sulfide Mediating both Excitatory and Inhibitory Effects in a Rat Model of Meningeal Nociception and Headache Generation. Front Neurol (2017) 0.75

Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature (2004) 9.66

Pungent products from garlic activate the sensory ion channel TRPA1. Proc Natl Acad Sci U S A (2005) 4.20

Distribution and function of the hydrogen sulfide-sensitive TRPA1 ion channel in rat urinary bladder. Eur Urol (2007) 2.21

TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ(9)-tetrahydrocannabiorcol. Nat Commun (2011) 1.43

Endogenous unsaturated C18 N-acylethanolamines are vanilloid receptor (TRPV1) agonists. J Biol Chem (2005) 1.39

TRPV1 in brain is involved in acetaminophen-induced antinociception. PLoS One (2010) 1.25

Vascular effects of anandamide and N-acylvanillylamines in the human forearm and skin microcirculation. Br J Pharmacol (2005) 1.00

TRPA1 contributes to the acute inflammatory response and mediates carrageenan-induced paw edema in the mouse. Sci Rep (2012) 0.99

Mechanisms underlying tissue selectivity of anandamide and other vanilloid receptor agonists. Mol Pharmacol (2002) 0.98

Effect of mucosal TRPV1 inhibition in allergic rhinitis. Basic Clin Pharmacol Toxicol (2011) 0.89

Monoacylglycerols activate TRPV1--a link between phospholipase C and TRPV1. PLoS One (2013) 0.86

Fatty acid amide hydrolase-dependent generation of antinociceptive drug metabolites acting on TRPV1 in the brain. PLoS One (2013) 0.85

Quantitative sensory testing of temperature thresholds: Possible biomarkers for persistent pain? J Rehabil Med (2016) 0.79

TRPV1 and TRPA1 stimulation induces MUC5B secretion in the human nasal airway in vivo. Clin Physiol Funct Imaging (2011) 0.78

In vitro TRPV1 activity of piperine derived amides. Bioorg Med Chem (2010) 0.77

Effect of hypoxia on vasodilator responses to S-nitroso-N-acetylpenicillamine and levcromakalim in guinea pig basilar artery. Naunyn Schmiedebergs Arch Pharmacol (2003) 0.76

TRPV4-mediated calcium influx and ciliary activity in human native airway epithelial cells. Basic Clin Pharmacol Toxicol (2013) 0.76