The focal complex of epithelial cells provides a signalling platform for interleukin-8 induction in response to bacterial pathogens.

PubWeight™: 0.77‹?›

🔗 View Article (PMC 4146656)

Published in Cell Microbiol on June 02, 2014

Authors

Tyson P Eucker1, Derrick R Samuelson, Mary Hunzicker-Dunn, Michael E Konkel

Author Affiliations

1: School of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, WA, 99164-7520, USA.

Articles cited by this

Integrins: bidirectional, allosteric signaling machines. Cell (2002) 36.25

Integrin signaling. Science (1999) 16.44

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene (2007) 11.85

Focal adhesion kinase: in command and control of cell motility. Nat Rev Mol Cell Biol (2005) 11.74

NF-kappaB: a key role in inflammatory diseases. J Clin Invest (2001) 9.66

Integrin-regulated FAK-Src signaling in normal and cancer cells. Curr Opin Cell Biol (2006) 8.52

Human chemokines: an update. Annu Rev Immunol (1997) 8.43

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling. Nature (1999) 8.42

Mitogen-activated protein kinases: specific messages from ubiquitous messengers. Mol Cell Biol (1999) 5.93

Multiple control of interleukin-8 gene expression. J Leukoc Biol (2002) 5.35

Networks and crosstalk: integrin signalling spreads. Nat Cell Biol (2002) 4.66

Src family kinases, key regulators of signal transduction. Oncogene (2004) 4.30

Helicobacter exploits integrin for type IV secretion and kinase activation. Nature (2007) 4.02

pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk. Mol Cell Biol (1995) 3.85

Focal adhesion regulation of cell behavior. Biochim Biophys Acta (2004) 3.83

Helicobacter pylori VacA, a paradigm for toxin multifunctionality. Nat Rev Microbiol (2005) 3.25

Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase. J Biol Chem (1996) 3.21

KSR is a scaffold required for activation of the ERK/MAPK module. Genes Dev (2002) 2.40

Identification and molecular cloning of a gene encoding a fibronectin-binding protein (CadF) from Campylobacter jejuni. Mol Microbiol (1997) 2.17

KSR: a MAPK scaffold of the Ras pathway? J Cell Sci (2001) 1.90

Paxillin serves as an ERK-regulated scaffold for coordinating FAK and Rac activation in epithelial morphogenesis. Mol Cell (2004) 1.86

Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis. Mol Cell (2003) 1.83

Maximal adherence and invasion of INT 407 cells by Campylobacter jejuni requires the CadF outer-membrane protein and microfilament reorganization. Microbiology (2003) 1.82

Interleukin-8 controls bacterial transepithelial translocation at the cost of epithelial destruction in experimental shigellosis. Infect Immun (1999) 1.68

Fibronectin: a multidomain host adhesin targeted by bacterial fibronectin-binding proteins. FEMS Microbiol Rev (2011) 1.67

Integrin regulation of epidermal growth factor (EGF) receptor and of EGF-dependent responses. Biochem Soc Trans (2004) 1.49

Altered synthetic response of Campylobacter jejuni to cocultivation with human epithelial cells is associated with enhanced internalization. Infect Immun (1992) 1.45

Examination of Campylobacter jejuni putative adhesins leads to the identification of a new protein, designated FlpA, required for chicken colonization. Infect Immun (2009) 1.30

FAK engages multiple pathways to maintain survival of fibroblasts and epithelia: differential roles for paxillin and p130Cas. J Cell Sci (2009) 1.29

Paxillin regulates androgen- and epidermal growth factor-induced MAPK signaling and cell proliferation in prostate cancer cells. J Biol Chem (2010) 1.24

Helicobacter pylori induced transactivation of SRE and AP-1 through the ERK signalling pathway in gastric cancer cells. Gut (2001) 1.24

Signal transduction in Campylobacter jejuni-induced cytokine production. Cell Microbiol (2005) 1.21

The blessings and curses of intestinal inflammation. Cell Host Microbe (2010) 1.20

Focal adhesion kinase: exploring Fak structure to gain insight into function. Int Rev Cell Mol Biol (2011) 1.19

Campylobacter jejuni FlpA binds fibronectin and is required for maximal host cell adherence. J Bacteriol (2010) 1.18

Regulation of endothelial cell function BY FAK and PYK2. Front Biosci (2004) 1.05

Helicobacter pylori induces interleukin-8 secretion by Toll-like receptor 2- and Toll-like receptor 5-dependent and -independent pathways. Infect Immun (2005) 1.03

The cooperative action of bacterial fibronectin-binding proteins and secreted proteins promote maximal Campylobacter jejuni invasion of host cells by stimulating membrane ruffling. Cell Microbiol (2011) 1.02

Kinetic and antigenic characterization of altered protein synthesis by Campylobacter jejuni during cultivation with human epithelial cells. J Infect Dis (1993) 1.00

The Vibrio parahaemolyticus Type III Secretion Systems manipulate host cell MAPK for critical steps in pathogenesis. BMC Microbiol (2010) 0.96

Invasion of host cells by Salmonella typhimurium requires focal adhesion kinase and p130Cas. Mol Biol Cell (2006) 0.95

Porins from Salmonella enterica serovar Typhimurium activate the transcription factors activating protein 1 and NF-kappaB through the Raf-1-mitogen-activated protein kinase cascade. Infect Immun (2002) 0.92

Interleukin-8 production by THP-1 cells stimulated by Salmonella enterica serovar Typhimurium porins is mediated by AP-1, NF-kappaB and MAPK pathways. Cytokine (2004) 0.89

The Campylobacter jejuni CiaD effector protein activates MAP kinase signaling pathways and is required for the development of disease. Cell Commun Signal (2013) 0.88

Paxillin is a novel cellular target for converging Helicobacter pylori-induced cellular signaling. Am J Physiol Gastrointest Liver Physiol (2011) 0.79

Articles by these authors

Comparative metagenomics reveals host specific metavirulomes and horizontal gene transfer elements in the chicken cecum microbiome. PLoS One (2008) 1.86

Maximal adherence and invasion of INT 407 cells by Campylobacter jejuni requires the CadF outer-membrane protein and microfilament reorganization. Microbiology (2003) 1.82

Greater diversity of Shiga toxin-encoding bacteriophage insertion sites among Escherichia coli O157:H7 isolates from cattle than in those from humans. Appl Environ Microbiol (2006) 1.71

Follicle-stimulating hormone activation of hypoxia-inducible factor-1 by the phosphatidylinositol 3-kinase/AKT/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is necessary for induction of select protein markers of follicular differentiation. J Biol Chem (2004) 1.53

Induction of cyclin D2 in rat granulosa cells requires FSH-dependent relief from FOXO1 repression coupled with positive signals from Smad. J Biol Chem (2004) 1.48

Fibronectin-facilitated invasion of T84 eukaryotic cells by Campylobacter jejuni occurs preferentially at the basolateral cell surface. Infect Immun (2002) 1.36

Type III secretion system 1 genes in Vibrio parahaemolyticus are positively regulated by ExsA and negatively regulated by ExsD. Mol Microbiol (2008) 1.34

Differentiation of Campylobacter coli, Campylobacter jejuni, Campylobacter lari, and Campylobacter upsaliensis by a multiplex PCR developed from the nucleotide sequence of the lipid A gene lpxA. J Clin Microbiol (2004) 1.32

Examination of Campylobacter jejuni putative adhesins leads to the identification of a new protein, designated FlpA, required for chicken colonization. Infect Immun (2009) 1.30

Identification of a Campylobacter jejuni-secreted protein required for maximal invasion of host cells. Mol Microbiol (2009) 1.27

Role of the phosphatidylinositol-3-kinase and extracellular regulated kinase pathways in the induction of hypoxia-inducible factor (HIF)-1 activity and the HIF-1 target vascular endothelial growth factor in ovarian granulosa cells in response to follicle-stimulating hormone. Endocrinology (2008) 1.27

Follicle-stimulating hormone activates extracellular signal-regulated kinase but not extracellular signal-regulated kinase kinase through a 100-kDa phosphotyrosine phosphatase. J Biol Chem (2002) 1.27

Production of organic acids by probiotic lactobacilli can be used to reduce pathogen load in poultry. PLoS One (2012) 1.26

The Campylobacter jejuni response regulator, CbrR, modulates sodium deoxycholate resistance and chicken colonization. J Bacteriol (2005) 1.25

Culture of Campylobacter jejuni with sodium deoxycholate induces virulence gene expression. J Bacteriol (2008) 1.25

Role of the small Rho GTPases Rac1 and Cdc42 in host cell invasion of Campylobacter jejuni. Cell Microbiol (2007) 1.24

Follicle-stimulating hormone/cAMP regulation of aromatase gene expression requires beta-catenin. Proc Natl Acad Sci U S A (2006) 1.18

Acute signaling by the LH receptor is independent of protein kinase C activation. Endocrinology (2002) 1.18

Characterization of genetically matched isolates of Campylobacter jejuni reveals that mutations in genes involved in flagellar biosynthesis alter the organism's virulence potential. Appl Environ Microbiol (2007) 1.17

Quantification of the relative roles of niche and neutral processes in structuring gastrointestinal microbiomes. Proc Natl Acad Sci U S A (2012) 1.10

Campylobacter jejuni infection of differentiated THP-1 macrophages results in interleukin 1 beta release and caspase-1-independent apoptosis. Microbiology (2004) 1.08

GnRH regulates early growth response protein 1 transcription through multiple promoter elements. Mol Endocrinol (2002) 1.06

Lhcgr expression in granulosa cells: roles for PKA-phosphorylated β-catenin, TCF3, and FOXO1. Mol Endocrinol (2013) 1.06

Identification of Campylobacter jejuni proteins recognized by maternal antibodies of chickens. Appl Environ Microbiol (2008) 1.04

Type III secretion system 1 of Vibrio parahaemolyticus induces oncosis in both epithelial and monocytic cell lines. Microbiology (2009) 1.04

The cooperative action of bacterial fibronectin-binding proteins and secreted proteins promote maximal Campylobacter jejuni invasion of host cells by stimulating membrane ruffling. Cell Microbiol (2011) 1.02

Campylobacter jejuni survival within human epithelial cells is enhanced by the secreted protein CiaI. Mol Microbiol (2011) 1.00

The Campylobacter jejuni CiaC virulence protein is secreted from the flagellum and delivered to the cytosol of host cells. Front Cell Infect Microbiol (2012) 0.97

Investigating antibacterial effects of garlic (Allium sativum) concentrate and garlic-derived organosulfur compounds on Campylobacter jejuni by using Fourier transform infrared spectroscopy, Raman spectroscopy, and electron microscopy. Appl Environ Microbiol (2011) 0.96

Signal transduction pathways activated by chorionic gonadotropin in the primate endometrial epithelial cells. Biol Reprod (2003) 0.96

Green fluorescent protein-expressing Escherichia coli as a selective probe for HOCl generation within neutrophils. Biochemistry (2005) 0.95

Vp1659 is a Vibrio parahaemolyticus type III secretion system 1 protein that contributes to translocation of effector proteins needed to induce cytolysis, autophagy, and disruption of actin structure in HeLa cells. J Bacteriol (2010) 0.95

Robust computational analysis of rRNA hypervariable tag datasets. PLoS One (2010) 0.93

Amino-terminal residues dictate the export efficiency of the Campylobacter jejuni filament proteins via the flagellum. Mol Microbiol (2010) 0.92

Luteinizing hormone receptor activation in ovarian granulosa cells promotes protein kinase A-dependent dephosphorylation of microtubule-associated protein 2D. Mol Endocrinol (2008) 0.92

Aspartic acid 564 in the third cytoplasmic loop of the luteinizing hormone/choriogonadotropin receptor is crucial for phosphorylation-independent interaction with arrestin2. J Biol Chem (2002) 0.92

In vivo tracking of Campylobacter jejuni by using a novel recombinant expressing green fluorescent protein. Appl Environ Microbiol (2003) 0.91

Expression patterns and role of the CadF protein in Campylobacter jejuni and Campylobacter coli. FEMS Microbiol Lett (2007) 0.90

Regulation of type III secretion system 1 gene expression in Vibrio parahaemolyticus is dependent on interactions between ExsA, ExsC, and ExsD. Virulence (2010) 0.90

Campylobacter jejuni invade chicken LMH cells inefficiently and stimulate differential expression of the chicken CXCLi1 and CXCLi2 cytokines. Microbiology (2008) 0.89

Infrared and Raman spectroscopic studies of the antimicrobial effects of garlic concentrates and diallyl constituents on foodborne pathogens. Anal Chem (2011) 0.89

The Campylobacter jejuni CiaD effector protein activates MAP kinase signaling pathways and is required for the development of disease. Cell Commun Signal (2013) 0.88

Neuronal microtubule-associated protein 2D is a dual a-kinase anchoring protein expressed in rat ovarian granulosa cells. J Biol Chem (2004) 0.87

Comparative studies of Campylobacter jejuni genomic diversity reveal the importance of core and dispensable genes in the biology of this enigmatic food-borne pathogen. Curr Opin Biotechnol (2009) 0.87

Luteinizing hormone receptor-stimulated progesterone production by preovulatory granulosa cells requires protein kinase A-dependent activation/dephosphorylation of the actin dynamizing protein cofilin. Mol Endocrinol (2010) 0.86

Identification of potential type III secretion proteins via heterologous expression of Vibrio parahaemolyticus DNA. Appl Environ Microbiol (2012) 0.84

Expression and purification of native and truncated forms of CadF, an outer membrane protein of Campylobacter. Int J Biol Macromol (2006) 0.83

Detecting and tracking nosocomial methicillin-resistant Staphylococcus aureus using a microfluidic SERS biosensor. Anal Chem (2013) 0.83

Comprehensive detection and discrimination of Campylobacter species by use of confocal micro-Raman spectroscopy and multilocus sequence typing. J Clin Microbiol (2012) 0.83

Analysis of the pan genome of Campylobacter jejuni isolates recovered from poultry by pulsed-field gel electrophoresis, multilocus sequence typing (MLST), and repetitive sequence polymerase chain reaction (rep-PCR) reveals different discriminatory capabilities. Microb Ecol (2009) 0.83

Antimicrobial effect of diallyl sulphide on Campylobacter jejuni biofilms. J Antimicrob Chemother (2012) 0.82

Hsp27 is persistently expressed in zebrafish skeletal and cardiac muscle tissues but dispensable for their morphogenesis. Cell Stress Chaperones (2009) 0.82

Serine phosphorylation of cortactin is required for maximal host cell invasion by Campylobacter jejuni. Cell Commun Signal (2013) 0.79

Cloning, characterization, and expression of the rat relaxin gene. Gene (2003) 0.79

Investigating the responses of Cronobacter sakazakii to garlic-drived organosulfur compounds: a systematic study of pathogenic-bacterium injury by use of high-throughput whole-transcriptome sequencing and confocal micro-raman spectroscopy. Appl Environ Microbiol (2013) 0.78

Invasion of epithelial cells by Campylobacter jejuni is independent of caveolae. Cell Commun Signal (2013) 0.77

Chromosomal His-tagging: an alternative approach to membrane protein purification. Proteomics (2007) 0.77