Antibiotics induce redox-related physiological alterations as part of their lethality.

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Published in Proc Natl Acad Sci U S A on May 06, 2014

Authors

Daniel J Dwyer1, Peter A Belenky1, Jason H Yang1, I Cody MacDonald1, Jeffrey D Martell2, Noriko Takahashi3, Clement T Y Chan1, Michael A Lobritz4, Dana Braff1, Eric G Schwarz1, Jonathan D Ye1, Mekhala Pati5, Maarten Vercruysse3, Paul S Ralifo5, Kyle R Allison6, Ahmad S Khalil7, Alice Y Ting2, Graham C Walker3, James J Collins8

Author Affiliations

1: Howard Hughes Medical Institute,Departments of Biomedical Engineering andCenter of Synthetic Biology, Boston University, Boston, MA 02215;
2: Departments of Chemistry and.
3: Biology, Massachusetts Institute of Technology, Cambridge, MA 02139;
4: Howard Hughes Medical Institute,Departments of Biomedical Engineering andCenter of Synthetic Biology, Boston University, Boston, MA 02215;Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115;Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02114;
5: Chemistry, and.
6: Department of Systems Biology, Columbia University, New York, NY 10032; and.
7: Departments of Biomedical Engineering andCenter of Synthetic Biology, Boston University, Boston, MA 02215;Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115;
8: Howard Hughes Medical Institute,Departments of Biomedical Engineering andCenter of Synthetic Biology, Boston University, Boston, MA 02215;Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115;Department of Medicine, Boston University School of Medicine, Boston, MA 02118 jcollins@bu.edu.

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