Published in Development on May 01, 2014
An Optogenetic Method to Modulate Cell Contractility during Tissue Morphogenesis. Dev Cell (2015) 1.59
Stable Force Balance between Epithelial Cells Arises from F-Actin Turnover. Dev Cell (2015) 1.49
E-cadherin junctions as active mechanical integrators in tissue dynamics. Nat Cell Biol (2015) 1.43
Dynamic myosin phosphorylation regulates contractile pulses and tissue integrity during epithelial morphogenesis. J Cell Biol (2014) 1.17
Intracellular signalling and intercellular coupling coordinate heterogeneous contractile events to facilitate tissue folding. Nat Commun (2015) 0.98
RhoA GTPase inhibition organizes contraction during epithelial morphogenesis. J Cell Biol (2016) 0.88
Cdc25 and the importance of G2 control: insights from developmental biology. Cell Cycle (2014) 0.88
Spatial and temporal aspects of Wnt signaling and planar cell polarity during vertebrate embryonic development. Semin Cell Dev Biol (2015) 0.87
Interplay of active processes modulates tension and drives phase transition in self-renewing, motor-driven cytoskeletal networks. Nat Commun (2016) 0.84
Complete canthi removal reveals that forces from the amnioserosa alone are sufficient to drive dorsal closure in Drosophila. Mol Biol Cell (2014) 0.84
Flow-dependent myosin recruitment during Drosophila cellularization requires zygotic dunk activity. Development (2016) 0.84
Modular activation of Rho1 by GPCR signalling imparts polarized myosin II activation during morphogenesis. Nat Cell Biol (2016) 0.82
Early steps in inner ear development: induction and morphogenesis of the otic placode. Front Pharmacol (2015) 0.82
Mechanical Coupling between Endoderm Invagination and Axis Extension in Drosophila. PLoS Biol (2015) 0.82
Regulation of tissue morphodynamics: an important role for actomyosin contractility. Curr Opin Genet Dev (2015) 0.82
Myosin II promotes the anisotropic loss of the apical domain during Drosophila neuroblast ingression. J Cell Biol (2017) 0.81
Pdx1 regulates pancreas tubulogenesis and E-cadherin expression. Development (2015) 0.80
The roles and regulation of multicellular rosette structures during morphogenesis. Development (2014) 0.80
NF2/Merlin mediates contact-dependent inhibition of EGFR mobility and internalization via cortical actomyosin. J Cell Biol (2015) 0.79
Emergence of an Apical Epithelial Cell Surface In Vivo. Dev Cell (2016) 0.79
Cellular systems for epithelial invagination. Philos Trans R Soc Lond B Biol Sci (2017) 0.79
Taking the strain: quantifying the contributions of all cell behaviours to changes in epithelial shape. Philos Trans R Soc Lond B Biol Sci (2017) 0.79
Complex structures from patterned cell sheets. Philos Trans R Soc Lond B Biol Sci (2017) 0.79
Transcriptional Pre-patterning of Drosophila Gastrulation. Curr Biol (2017) 0.78
Shape Transformations of Epithelial Shells. Biophys J (2016) 0.78
From morphogen to morphogenesis and back. Nature (2017) 0.77
MRCK-1 Drives Apical Constriction in C. elegans by Linking Developmental Patterning to Force Generation. Curr Biol (2016) 0.77
CRB3A Controls the Morphology and Cohesion of Cancer Cells through Ehm2/p114RhoGEF-Dependent Signaling. Mol Cell Biol (2015) 0.77
Protein tyrosine kinase 7 is essential for tubular morphogenesis of the Wolffian duct. Dev Biol (2016) 0.77
Notochord morphogenesis in mice: Current understanding & open questions. Dev Dyn (2016) 0.76
The organelle of differentiation in embryos: the cell state splitter. Theor Biol Med Model (2016) 0.76
Functional dichotomy and distinct nanoscale assemblies of a cell cycle-controlled bipolar zinc-finger regulator. Elife (2016) 0.76
Myosin light-chain phosphatase regulates basal actomyosin oscillations during morphogenesis. Nat Commun (2016) 0.76
Apical constriction and epithelial invagination are regulated by BMP activity. Biol Open (2015) 0.76
αE-catenin-dependent mechanotransduction is essential for proper convergent extension in zebrafish. Biol Open (2016) 0.75
Uncoupling apical constriction from tissue invagination. Elife (2017) 0.75
Proliferation-independent regulation of organ size by Fgf/Notch signaling. Elife (2017) 0.75
Beyond Turing: mechanochemical pattern formation in biological tissues. Biol Direct (2016) 0.75
Dynamics of cell polarity in tissue morphogenesis: a comparative view from Drosophila and Ciona. F1000Res (2016) 0.75
Force transmission in epithelial tissues. Dev Dyn (2016) 0.75
Squeezing out in a "tug of war": The role of myosin in neural stem cell delamination. J Cell Biol (2017) 0.75
Moving Inward: Establishing the Mammalian Inner Cell Mass. Dev Cell (2015) 0.75
DAAM1 stabilizes epithelial junctions by restraining WAVE complex-dependent lateral membrane motility. J Cell Biol (2016) 0.75
Muscle versus Snail: Muscle wins. J Cell Biol (2016) 0.75
Histone demethylase KDM4B regulates otic vesicle invagination via epigenetic control of Dlx3 expression. J Cell Biol (2015) 0.75
Computational models of airway branching morphogenesis. Semin Cell Dev Biol (2016) 0.75
Cytoskeletal Stability in the Auditory Organ In Vivo: RhoA Is Dispensable for Wound Healing but Essential for Hair Cell Development. eNeuro (2017) 0.75
Notch-dependent epithelial fold determines boundary formation between developmental fields in the Drosophila antenna. PLoS Genet (2017) 0.75
Activation and synchronization of the oscillatory morphodynamics in multicellular monolayer. Proc Natl Acad Sci U S A (2017) 0.75
Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1. Nat Commun (2017) 0.75
Actomyosin-based tissue folding requires a multicellular myosin gradient. Development (2017) 0.75
Progressive polarity loss and luminal collapse disrupt tissue organization in carcinoma. Genes Dev (2017) 0.75
Bud detachment in Hydra requires activation of FGFR and a Rho - ROCK - myosin II signaling pathway to ensure formation of a basal constriction. Dev Dyn (2017) 0.75
Mechanobiology of collective cell behaviours. Nat Rev Mol Cell Biol (2017) 0.75
Rho GTPases: biochemistry and biology. Annu Rev Cell Dev Biol (2005) 16.77
Deconstructing the cadherin-catenin-actin complex. Cell (2005) 8.39
Two distinct actin networks drive the protrusion of migrating cells. Science (2004) 7.69
Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly. Cell (2005) 7.62
Coordination of Rho GTPase activities during cell protrusion. Nature (2009) 6.54
Self-organizing optic-cup morphogenesis in three-dimensional culture. Nature (2011) 6.51
Mechanism and function of formins in the control of actin assembly. Annu Rev Biochem (2007) 5.36
Pulsed contractions of an actin-myosin network drive apical constriction. Nature (2008) 5.25
Multiple forces contribute to cell sheet morphogenesis for dorsal closure in Drosophila. J Cell Biol (2000) 5.01
Cortical flows powered by asymmetrical contraction transport PAR proteins to establish and maintain anterior-posterior polarity in the early C. elegans embryo. Dev Cell (2004) 4.84
Cortical flow in animal cells. Science (1988) 4.66
alpha-Catenin as a tension transducer that induces adherens junction development. Nat Cell Biol (2010) 4.42
Forces for morphogenesis investigated with laser microsurgery and quantitative modeling. Science (2003) 4.42
Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo. Nature (2001) 4.15
Viscoelastic retraction of single living stress fibers and its impact on cell shape, cytoskeletal organization, and extracellular matrix mechanics. Biophys J (2006) 4.06
Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments. J Cell Biol (1997) 4.00
Pulsed forces timed by a ratchet-like mechanism drive directed tissue movement during dorsal closure. Cell (2009) 3.92
Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin. J Cell Biol (1995) 3.86
Assembly mechanism of the contractile ring for cytokinesis by fission yeast. Science (2007) 3.82
folded gastrulation, cell shape change and the control of myosin localization. Development (2005) 3.49
Myosin II dynamics are regulated by tension in intercalating cells. Dev Cell (2009) 3.49
Integration of contractile forces during tissue invagination. J Cell Biol (2010) 3.39
Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II-dependent manner. J Cell Biol (2010) 3.25
GFP-moesin illuminates actin cytoskeleton dynamics in living tissue and demonstrates cell shape changes during morphogenesis in Drosophila. Dev Biol (1997) 3.24
Mechanical induction of Twist in the Drosophila foregut/stomodeal primordium. Curr Biol (2003) 3.20
Molecular mechanisms of nonmuscle myosin-II regulation. Curr Opin Cell Biol (1999) 3.05
Apical constriction: a cell shape change that can drive morphogenesis. Dev Biol (2009) 2.90
Cytoplasmic filaments and morphogenetic movement in the amphibian neural tube. Dev Biol (1967) 2.84
EPLIN mediates linkage of the cadherin catenin complex to F-actin and stabilizes the circumferential actin belt. Proc Natl Acad Sci U S A (2007) 2.82
Noninvasive imaging beyond the diffraction limit of 3D dynamics in thickly fluorescent specimens. Cell (2012) 2.72
The Rho GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation. Cell (1997) 2.62
Shroom, a PDZ domain-containing actin-binding protein, is required for neural tube morphogenesis in mice. Cell (1999) 2.56
Forces in tissue morphogenesis and patterning. Cell (2013) 2.55
Drosophila RhoGEF2 associates with microtubule plus ends in an EB1-dependent manner. Curr Biol (2004) 2.53
Wnt/Frizzled signaling controls C. elegans gastrulation by activating actomyosin contractility. Curr Biol (2006) 2.53
Control of Drosophila gastrulation by apical localization of adherens junctions and RhoGEF2. Science (2007) 2.51
Mechanics of chromosome separation during mitosis in Fusarium (Fungi imperfecti): new evidence from ultrastructural and laser microbeam experiments. J Cell Biol (1981) 2.50
Shroom regulates epithelial cell shape via the apical positioning of an actomyosin network. J Cell Sci (2005) 2.50
Shroom induces apical constriction and is required for hingepoint formation during neural tube closure. Curr Biol (2003) 2.49
Dynamic changes in the distribution of cytoplasmic myosin during Drosophila embryogenesis. Development (1991) 2.47
Live-cell delamination counterbalances epithelial growth to limit tissue overcrowding. Nature (2012) 2.42
Structural memory in the contractile ring makes the duration of cytokinesis independent of cell size. Cell (2009) 2.42
The mechanical basis of morphogenesis. I. Epithelial folding and invagination. Dev Biol (1981) 2.42
Triggering a cell shape change by exploiting preexisting actomyosin contractions. Science (2012) 2.41
Gastrulation in Drosophila: the formation of the ventral furrow and posterior midgut invaginations. Development (1991) 2.41
Anisotropies in cortical tension reveal the physical basis of polarizing cortical flows. Nature (2010) 2.39
Nonmuscle myosin II generates forces that transmit tension and drive contraction in multiple tissues during dorsal closure. Curr Biol (2005) 2.39
Regulation of cytoplasmic and smooth muscle myosin. Curr Opin Cell Biol (1991) 2.39
A putative cell signal encoded by the folded gastrulation gene coordinates cell shape changes during Drosophila gastrulation. Cell (1994) 2.36
The Drosophila gastrulation gene concertina encodes a G alpha-like protein. Cell (1991) 2.34
Actin stress fibers--assembly, dynamics and biological roles. J Cell Sci (2012) 2.33
Apoptotic force and tissue dynamics during Drosophila embryogenesis. Science (2008) 2.33
Actin cortex mechanics and cellular morphogenesis. Trends Cell Biol (2012) 2.32
Biochemical and structural definition of the l-afadin- and actin-binding sites of alpha-catenin. J Biol Chem (2002) 2.31
Force generation, transmission, and integration during cell and tissue morphogenesis. Annu Rev Cell Dev Biol (2011) 2.28
Tissue deformation modulates twist expression to determine anterior midgut differentiation in Drosophila embryos. Dev Cell (2008) 2.27
Cortical F-actin stabilization generates apical-lateral patterns of junctional contractility that integrate cells into epithelia. Nat Cell Biol (2014) 2.26
Reactivation of intestinal epithelial cell brush border motility: ATP-dependent contraction via a terminal web contractile ring. J Cell Biol (1982) 2.23
Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens. Nat Cell Biol (2012) 2.23
Tissue elongation requires oscillating contractions of a basal actomyosin network. Nat Cell Biol (2010) 2.15
Shroom3-mediated recruitment of Rho kinases to the apical cell junctions regulates epithelial and neuroepithelial planar remodeling. Development (2008) 2.14
DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in Drosophila. Genes Dev (1998) 2.14
Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling. J Cell Biol (2012) 2.12
Genetics and development of neural tube defects. J Pathol (2010) 2.10
Non-sarcomeric mode of myosin II organization in the fibroblast lamellum. J Cell Biol (1993) 2.10
Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulation. Physiol Rev (2011) 2.06
A quantitative analysis of contractility in active cytoskeletal protein networks. Biophys J (2008) 2.05
Apical domain polarization localizes actin-myosin activity to drive ratchet-like apical constriction. Nat Cell Biol (2013) 2.00
Planar cell polarity links axes of spatial dynamics in neural-tube closure. Cell (2012) 1.98
Differential positioning of adherens junctions is associated with initiation of epithelial folding. Nature (2012) 1.98
P115 RhoGEF and microtubules decide the direction apoptotic cells extrude from an epithelium. J Cell Biol (2009) 1.97
The Drosophila afadin homologue Canoe regulates linkage of the actin cytoskeleton to adherens junctions during apical constriction. J Cell Biol (2009) 1.90
Mechanical signals trigger Myosin II redistribution and mesoderm invagination in Drosophila embryos. Sci Signal (2009) 1.89
The continuing challenge of understanding, preventing, and treating neural tube defects. Science (2013) 1.86
Mechanosensing through cooperative interactions between myosin II and the actin crosslinker cortexillin I. Curr Biol (2009) 1.86
Gastrulation movements: the logic and the nuts and bolts. Dev Cell (2005) 1.80
Cytoskeletal dynamics and supracellular organisation of cell shape fluctuations during dorsal closure. Development (2010) 1.80
Polar actomyosin contractility destabilizes the position of the cytokinetic furrow. Nature (2011) 1.78
Convergence and extension at gastrulation require a myosin IIB-dependent cortical actin network. Development (2008) 1.77
Mechanisms of cell positioning during C. elegans gastrulation. Development (2003) 1.77
F-actin buckling coordinates contractility and severing in a biomimetic actomyosin cortex. Proc Natl Acad Sci U S A (2012) 1.65
Pulsation and stabilization: contractile forces that underlie morphogenesis. Dev Biol (2009) 1.65
Shroom family proteins regulate gamma-tubulin distribution and microtubule architecture during epithelial cell shape change. Development (2007) 1.64
Myosin II regulates complex cellular arrangement and epithelial architecture in Drosophila. Dev Cell (2007) 1.63
Zonula occludens-1 and -2 regulate apical cell structure and the zonula adherens cytoskeleton in polarized epithelia. Mol Biol Cell (2011) 1.60
Active multistage coarsening of actin networks driven by myosin motors. Proc Natl Acad Sci U S A (2011) 1.56
The PAR complex regulates pulsed actomyosin contractions during amnioserosa apical constriction in Drosophila. Development (2010) 1.55
Sequential activation of apical and basolateral contractility drives ascidian endoderm invagination. Curr Biol (2010) 1.53
Diaphanous regulates myosin and adherens junctions to control cell contractility and protrusive behavior during morphogenesis. Development (2008) 1.45
Dynamic and structural signatures of lamellar actomyosin force generation. Mol Biol Cell (2011) 1.40
Punctuated actin contractions during convergent extension and their permissive regulation by the non-canonical Wnt-signaling pathway. J Cell Sci (2011) 1.39
The behaviour and function of bottle cells during gastrulation of Xenopus laevis. Development (1988) 1.37
Actomyosin contractility and microtubules drive apical constriction in Xenopus bottle cells. Dev Biol (2007) 1.33
Cell polarity and gastrulation in C. elegans. Development (2002) 1.33
NMII forms a contractile transcellular sarcomeric network to regulate apical cell junctions and tissue geometry. Curr Biol (2013) 1.29
Epithelial morphogenesis in embryos: asymmetries, motors and brakes. Trends Genet (2008) 1.28
alpha -Catenin binds directly to spectrin and facilitates spectrin-membrane assembly in vivo. J Biol Chem (2000) 1.27
Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia. Proc Natl Acad Sci U S A (2011) 1.25
Willin and Par3 cooperatively regulate epithelial apical constriction through aPKC-mediated ROCK phosphorylation. Nat Cell Biol (2011) 1.24
Dpp signalling orchestrates dorsal closure by regulating cell shape changes both in the amnioserosa and in the epidermis. Mech Dev (2007) 1.23
Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination. Nat Methods (2013) 3.59
Apical constriction: a cell shape change that can drive morphogenesis. Dev Biol (2009) 2.90
Noninvasive imaging beyond the diffraction limit of 3D dynamics in thickly fluorescent specimens. Cell (2012) 2.72
Wnt/Frizzled signaling controls C. elegans gastrulation by activating actomyosin contractility. Curr Biol (2006) 2.53
Triggering a cell shape change by exploiting preexisting actomyosin contractions. Science (2012) 2.41
C. elegans PAR proteins function by mobilizing and stabilizing asymmetrically localized protein complexes. Curr Biol (2004) 2.02
Mechanisms of cell positioning during C. elegans gastrulation. Development (2003) 1.77
Using RNA interference to identify genes required for RNA interference. Proc Natl Acad Sci U S A (2002) 1.63
The tardigrade Hypsibius dujardini, a new model for studying the evolution of development. Dev Biol (2007) 1.56
PAR proteins regulate microtubule dynamics at the cell cortex in C. elegans. Curr Biol (2003) 1.30
The forces that position a mitotic spindle asymmetrically are tethered until after the time of spindle assembly. J Cell Biol (2004) 1.17
A cell cycle timer for asymmetric spindle positioning. PLoS Biol (2009) 1.16
Segmental expression of Pax3/7 and engrailed homologs in tardigrade development. Dev Genes Evol (2007) 1.08
RhoA activation during polarization and cytokinesis of the early Caenorhabditis elegans embryo is differentially dependent on NOP-1 and CYK-4. Mol Biol Cell (2012) 1.05
Culture and manipulation of embryonic cells. Methods Cell Biol (2012) 0.95
Gastrulation in C. elegans. WormBook (2005) 0.95
In vivo roles for Arp2/3 in cortical actin organization during C. elegans gastrulation. J Cell Sci (2009) 0.93
How signaling between cells can orient a mitotic spindle. Semin Cell Dev Biol (2011) 0.93
Dynamic localization of C. elegans TPR-GoLoco proteins mediates mitotic spindle orientation by extrinsic signaling. Development (2011) 0.92
Asymmetric spindle positioning. Curr Opin Cell Biol (2005) 0.90
RNA interference can be used to disrupt gene function in tardigrades. Dev Genes Evol (2012) 0.87
Extracellular control of PAR protein localization during asymmetric cell division in the C. elegans embryo. Development (2010) 0.87
Overcoming redundancy: an RNAi enhancer screen for morphogenesis genes in Caenorhabditis elegans. Genetics (2011) 0.86
Actin-based forces driving embryonic morphogenesis in Caenorhabditis elegans. Curr Opin Genet Dev (2006) 0.85
Internalization of multiple cells during C. elegans gastrulation depends on common cytoskeletal mechanisms but different cell polarity and cell fate regulators. Dev Biol (2010) 0.84
Redundant canonical and noncanonical Caenorhabditis elegans p21-activated kinase signaling governs distal tip cell migrations. G3 (Bethesda) (2013) 0.82
Embryonic development: a new SPN on cell fate specification. Curr Biol (2002) 0.81
Neural tube closure: the curious case of shrinking junctions. Curr Biol (2012) 0.78
RNA interference in Caenorhabditis elegans. Methods Mol Biol (2005) 0.77
Wnt signaling during Caenorhabditis elegans embryonic development. Methods Mol Biol (2008) 0.77
RNA interference: silencing in the cytoplasm and nucleus. Curr Opin Mol Ther (2003) 0.77
Symmetry breaking in C. elegans: another gift from the sperm. Dev Cell (2006) 0.76
Asymmetric cell division: a new way to divide unequally. Curr Biol (2010) 0.75
Bob Goldstein: cell biology by way of development. Interviewed by Caitlin Sedwick. J Cell Biol (2013) 0.75
Self-organized cytoskeletal alignment during mesoderm invagination. Philos Trans R Soc Lond B Biol Sci (2020) 0.75
Asymmetric division: a kinesin for spindle positioning. Curr Biol (2005) 0.75