A systems biology approach utilizing a mouse diversity panel identifies genetic differences influencing isoniazid-induced microvesicular steatosis.

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Published in Toxicol Sci on May 20, 2014

Authors

Rachel J Church1, Hong Wu2, Merrie Mosedale1, Susan J Sumner3, Wimal Pathmasiri3, Catherine L Kurtz4, Mathew T Pletcher5, John S Eaddy4, Karamjeet Pandher5, Monica Singer6, Ameesha Batheja6, Paul B Watkins7, Karissa Adkins2, Alison H Harrill8

Author Affiliations

1: Hamner-University of North Carolina Institute for Drug Safety Sciences, The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709 ahharrill@uams.edu.
2: Drug Safety Research and Development, Pfizer Global Research and Development, Groton, Connecticut 06340 ahharrill@uams.edu.
3: Discovery Sciences, RTI International, Research Triangle Park, North Carolina 27709.
4: Hamner-University of North Carolina Institute for Drug Safety Sciences, The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709.
5: Drug Safety Research and Development, Pfizer Global Research and Development, Groton, Connecticut 06340.
6: Janssen Research and Development, Drug Safety Sciences, Raritan, New Jersey 08869.
7: Hamner-University of North Carolina Institute for Drug Safety Sciences, The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709 Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599.
8: Hamner-University of North Carolina Institute for Drug Safety Sciences, The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709 Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 The University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205 ahharrill@uams.edu.

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