Published in Curr Opin Gastroenterol on March 01, 2012
Choline Supplementation on Fetal Growth in Gestational Diabetes Mellitus | NCT04302168
Dysbiosis of the gut microbiota in disease. Microb Ecol Health Dis (2015) 1.33
The Gordian Knot of dysbiosis, obesity and NAFLD. Nat Rev Gastroenterol Hepatol (2013) 1.06
Nonalcoholic fatty liver disease: a comprehensive review of a growing epidemic. World J Gastroenterol (2014) 1.02
Dietary intake, nutrition, and fetal alcohol spectrum disorders in the Western Cape Province of South Africa. Reprod Toxicol (2014) 1.01
Oxidative stress, cardiolipin and mitochondrial dysfunction in nonalcoholic fatty liver disease. World J Gastroenterol (2014) 0.99
Low-carbohydrate ketogenic diets, glucose homeostasis, and nonalcoholic fatty liver disease. Curr Opin Clin Nutr Metab Care (2012) 0.99
Nutrition in pregnancy: the argument for including a source of choline. Int J Womens Health (2013) 0.98
A systems biology approach utilizing a mouse diversity panel identifies genetic differences influencing isoniazid-induced microvesicular steatosis. Toxicol Sci (2014) 0.92
Circulating lysophosphatidylcholines are markers of a metabolically benign nonalcoholic fatty liver. Diabetes Care (2013) 0.88
Genetic signatures in choline and 1-carbon metabolism are associated with the severity of hepatic steatosis. FASEB J (2013) 0.85
EDI3 links choline metabolism to integrin expression, cell adhesion and spreading. Cell Adh Migr (2014) 0.84
Egg phospholipids and cardiovascular health. Nutrients (2015) 0.83
The effects of choline on hepatic lipid metabolism, mitochondrial function and antioxidative status in human hepatic C3A cells exposed to excessive energy substrates. Nutrients (2014) 0.83
Higher dietary choline intake is associated with lower risk of nonalcoholic fatty liver in normal-weight Chinese women. J Nutr (2014) 0.82
Non-alcoholic fatty liver disease, diet and gut microbiota. EXCLI J (2014) 0.81
Role of choline deficiency in the Fatty liver phenotype of mice fed a low protein, very low carbohydrate ketogenic diet. PLoS One (2013) 0.81
Associations of gut-flora-dependent metabolite trimethylamine-N-oxide, betaine and choline with non-alcoholic fatty liver disease in adults. Sci Rep (2016) 0.80
Epigenetics and nutritional environmental signals. Integr Comp Biol (2014) 0.80
Gut Microbiota and Lifestyle Interventions in NAFLD. Int J Mol Sci (2016) 0.79
Metabolic characterization of the natural progression of chronic hepatitis B. Genome Med (2016) 0.78
Gut Microbiota and Nonalcoholic Fatty Liver Disease: Insights on Mechanism and Application of Metabolomics. Int J Mol Sci (2016) 0.77
Mouse models of liver fibrosis mimic human liver fibrosis of different etiologies. Curr Pathobiol Rep (2014) 0.76
Choline, Its Potential Role in Nonalcoholic Fatty Liver Disease, and the Case for Human and Bacterial Genes. Adv Nutr (2016) 0.76
Alcoholic Steatosis in Different Strains of Rat: A Comparative Study. J Drug Alcohol Res (2015) 0.75
Choline and Cystine Deficient Diets in Animal Models with Hepatocellular Injury: Evaluation of Oxidative Stress and Expression of RAGE, TNF-α, and IL-1β. Oxid Med Cell Longev (2015) 0.75
Short-Term Hypocaloric High-Fiber and High-Protein Diet Improves Hepatic Steatosis Assessed by Controlled Attenuation Parameter. Clin Transl Gastroenterol (2016) 0.75
Nonalcoholic Fatty Liver Disease, the Gut Microbiome, and Diet. Adv Nutr (2017) 0.75
Metabolomic Fingerprinting in the Comprehensive Study of Liver Changes Associated with Onion Supplementation in Hypercholesterolemic Wistar Rats. Int J Mol Sci (2017) 0.75
The Potential of Metabolic Imaging. Semin Nucl Med (2016) 0.75
Effects of Choline on DNA Methylation and Macronutrient Metabolic Gene Expression in In Vitro Models of Hyperglycemia. Nutr Metab Insights (2016) 0.75
Choline Deficiency Causes Colonic Type II Natural Killer T (NKT) Cell Loss and Alleviates Murine Colitis under Type I NKT Cell Deficiency. PLoS One (2017) 0.75
Animal models of non-alcoholic fatty liver disease: current perspectives and recent advances. J Pathol (2016) 0.75
Metabolomic profiling distinction of human nonalcoholic fatty liver disease progression from a common rat model. Obesity (Silver Spring) (2017) 0.75
Hepatic vagus nerve regulates Kupffer cell activation via α7 nicotinic acetylcholine receptor in nonalcoholic steatohepatitis. J Gastroenterol (2017) 0.75
Choline prevents fetal overgrowth and normalizes placental fatty acid and glucose metabolism in a mouse model of maternal obesity. J Nutr Biochem (2017) 0.75
Nutritional approaches for managing obesity-associated metabolic diseases. J Endocrinol (2017) 0.75
Inflammation and cancer. Nature (2002) 53.78
Metabolite profiles and the risk of developing diabetes. Nat Med (2011) 12.22
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature (2006) 9.36
Human nutrition, the gut microbiome and the immune system. Nature (2011) 7.77
Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice. Proc Natl Acad Sci U S A (2006) 5.19
Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity. Nature (2011) 4.78
Unravelling the effects of the environment and host genotype on the gut microbiome. Nat Rev Microbiol (2011) 4.57
A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects. Nature (2011) 4.44
Endoplasmic reticulum stress in liver disease. J Hepatol (2010) 3.90
Identification of a physiologically relevant endogenous ligand for PPARalpha in liver. Cell (2009) 3.26
Bile acids as regulatory molecules. J Lipid Res (2009) 3.23
Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting. PLoS One (2010) 2.84
Choline: critical role during fetal development and dietary requirements in adults. Annu Rev Nutr (2006) 2.83
The gut microbiota modulates host energy and lipid metabolism in mice. J Lipid Res (2009) 2.59
Interactions between gut microbiota and host metabolism predisposing to obesity and diabetes. Annu Rev Med (2011) 2.59
Polymorphism of the PEMT gene and susceptibility to nonalcoholic fatty liver disease (NAFLD). FASEB J (2005) 2.34
Animal models of nonalcoholic fatty liver disease. Nat Rev Gastroenterol Hepatol (2010) 2.32
Bile acid transporters. J Lipid Res (2009) 2.31
Association between composition of the human gastrointestinal microbiome and development of fatty liver with choline deficiency. Gastroenterology (2010) 2.30
Dietary choline and betaine and the risk of distal colorectal adenoma in women. J Natl Cancer Inst (2007) 2.07
Dietary choline deficiency alters global and gene-specific DNA methylation in the developing hippocampus of mouse fetal brains. FASEB J (2006) 2.07
Common genetic polymorphisms affect the human requirement for the nutrient choline. FASEB J (2006) 1.88
The role of the gut microbiota in nonalcoholic fatty liver disease. Nat Rev Gastroenterol Hepatol (2010) 1.79
Plasma metabolomic profile in nonalcoholic fatty liver disease. Metabolism (2010) 1.77
Metabolomic analysis of livers and serum from high-fat diet induced obese mice. J Proteome Res (2010) 1.75
Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans. Proc Natl Acad Sci U S A (2005) 1.73
Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study. Am J Clin Nutr (2006) 1.71
Role of hepatic phospholipids in development of liver injury in Mdr2 (Abcb4) knockout mice. Liver Int (2008) 1.52
Recent advances in nonalcoholic fatty liver disease. Curr Opin Gastroenterol (2010) 1.52
Expression of the peroxisome proliferator activated receptor gamma gene is repressed by DNA methylation in visceral adipose tissue of mouse models of diabetes. BMC Biol (2009) 1.51
Usual choline and betaine dietary intake and incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study. BMC Cardiovasc Disord (2007) 1.47
Impaired de novo choline synthesis explains why phosphatidylethanolamine N-methyltransferase-deficient mice are protected from diet-induced obesity. J Biol Chem (2010) 1.44
An unexpected requirement for phosphatidylethanolamine N-methyltransferase in the secretion of very low density lipoproteins. J Biol Chem (2002) 1.43
Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas. J Biol Chem (2011) 1.40
Choline availability modulates human neuroblastoma cell proliferation and alters the methylation of the promoter region of the cyclin-dependent kinase inhibitor 3 gene. J Neurochem (2004) 1.40
In vivo methylation patterns of the leptin promoter in human and mouse. Epigenetics (2006) 1.29
A gender-specific role for phosphatidylethanolamine N-methyltransferase-derived phosphatidylcholine in the regulation of plasma high density and very low density lipoproteins in mice. J Biol Chem (2003) 1.27
Peroxisome proliferator-activated receptor-alpha (PPARalpha): at the crossroads of obesity, diabetes and cardiovascular disease. Atherosclerosis (2009) 1.25
Role of phosphatidylcholine biosynthesis in the regulation of lipoprotein homeostasis. Curr Opin Lipidol (2008) 1.24
Specific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione. J Biol Chem (2010) 1.22
Choline deficiency alters global histone methylation and epigenetic marking at the Re1 site of the calbindin 1 gene. FASEB J (2009) 1.21
Phosphatidylcholine homeostasis and liver failure. J Biol Chem (2005) 1.20
Bile acids and their nuclear receptor FXR: Relevance for hepatobiliary and gastrointestinal disease. Biochim Biophys Acta (2010) 1.20
Metabolomic profiling can predict which humans will develop liver dysfunction when deprived of dietary choline. FASEB J (2010) 1.18
Dietary choline restriction causes complex I dysfunction and increased H(2)O(2) generation in liver mitochondria. Carcinogenesis (2000) 1.18
Repeatability and measurement error in the assessment of choline and betaine dietary intake: the Atherosclerosis Risk in Communities (ARIC) study. Nutr J (2009) 1.16
Stress signaling in the methionine-choline-deficient model of murine fatty liver disease. Gastroenterology (2010) 1.13
Human serum metabonomic analysis reveals progression axes for glucose intolerance and insulin resistance statuses. J Proteome Res (2009) 1.12
Complications of long-term home total parenteral nutrition: their identification, prevention and treatment. Dig Dis Sci (2001) 1.10
Choline deficiency-induced liver damage is reversible in Pemt(-/-) mice. J Nutr (2002) 1.10
Betaine improves nonalcoholic fatty liver and associated hepatic insulin resistance: a potential mechanism for hepatoprotection by betaine. Am J Physiol Gastrointest Liver Physiol (2010) 1.08
Mitochondrial dysfunction in rat with nonalcoholic fatty liver Involvement of complex I, reactive oxygen species and cardiolipin. Biochim Biophys Acta (2007) 1.05
Oxidation of hepatic carnitine palmitoyl transferase-I (CPT-I) impairs fatty acid beta-oxidation in rats fed a methionine-choline deficient diet. PLoS One (2011) 1.04
Aberrant estrogen regulation of PEMT results in choline deficiency-associated liver dysfunction. J Biol Chem (2010) 1.04
Alterations in hepatic one-carbon metabolism and related pathways following a high-fat dietary intervention. Physiol Genomics (2011) 1.04
Methionine adenosyltransferase 1A gene deletion disrupts hepatic very low-density lipoprotein assembly in mice. Hepatology (2011) 1.02
Deletion of murine choline dehydrogenase results in diminished sperm motility. FASEB J (2010) 0.99
Nutritional genomics: defining the dietary requirement and effects of choline. J Nutr (2011) 0.98
Analysis of the liver mitochondrial proteome in response to ethanol and S-adenosylmethionine treatments: novel molecular targets of disease and hepatoprotection. Am J Physiol Gastrointest Liver Physiol (2010) 0.96
Dietary choline requirements of women: effects of estrogen and genetic variation. Am J Clin Nutr (2010) 0.92
Peroxisome proliferator-activated receptor {alpha} is responsible for the up-regulation of hepatic glucose-6-phosphatase gene expression in fasting and db/db Mice. J Biol Chem (2010) 0.92
Choline deficiency causes increased localization of transforming growth factor-beta1 signaling proteins and apoptosis in the rat liver. Pathobiology (1997) 0.89
Effects of prolonged (1 year) choline deficiency and subsequent re-feeding of choline on 1,2-sn-diradylglycerol, fatty acids and protein kinase C in rat liver. Carcinogenesis (1995) 0.87
Alterations in nucleotide pools in rats fed diets deficient in choline, methionine and/or folic acid. Carcinogenesis (1992) 0.87
Differential alterations in mitochondrial function induced by a choline-deficient diet: understanding fatty liver disease progression. Mitochondrion (2008) 0.86
Dietary choline deprivation impairs rat brain mitochondrial function and behavioral phenotype. J Nutr (2010) 0.84
Role of DNA damage and alterations in cytosine DNA methylation in rat liver carcinogenesis induced by a methyl-deficient diet. Mutat Res (2009) 0.84
Liver biochemical pathology of choline deficiency and of methyl group deficiency: a new orientation and assessment. Histol Histopathol (1995) 0.83
Mitochondrial dysfunction in choline deficiency-induced apoptosis in cultured rat hepatocytes. Free Radic Biol Med (2005) 0.82
Free radicals and lipid peroxidation in liver of rats kept on a diet devoid of choline. Free Radic Res Commun (1989) 0.81
Initiation of carcinogenesis by a dietary deficiency of choline in the absence of added carcinogens. Cancer Lett (1987) 0.81
Temporal correlation of pathology and DNA damage with gene expression in a choline-deficient model of rat liver injury. Hepatology (2005) 0.78
Quantitation of choline and its metabolites in tissues and foods by liquid chromatography/electrospray ionization-isotope dilution mass spectrometry. Anal Chem (2002) 2.35
Polymorphism of the PEMT gene and susceptibility to nonalcoholic fatty liver disease (NAFLD). FASEB J (2005) 2.34
Diet, methyl donors and DNA methylation: interactions between dietary folate, methionine and choline. J Nutr (2002) 2.33
Association between composition of the human gastrointestinal microbiome and development of fatty liver with choline deficiency. Gastroenterology (2010) 2.30
Dietary choline and betaine and the risk of distal colorectal adenoma in women. J Natl Cancer Inst (2007) 2.07
Dietary choline deficiency alters global and gene-specific DNA methylation in the developing hippocampus of mouse fetal brains. FASEB J (2006) 2.07
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women. Am J Clin Nutr (2013) 1.88
Common genetic polymorphisms affect the human requirement for the nutrient choline. FASEB J (2006) 1.88
Sex and menopausal status influence human dietary requirements for the nutrient choline. Am J Clin Nutr (2007) 1.76
Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans. Proc Natl Acad Sci U S A (2005) 1.73
Choline availability during embryonic development alters progenitor cell mitosis in developing mouse hippocampus. J Nutr (2003) 1.73
Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study. Am J Clin Nutr (2006) 1.71
Evidence-based criteria in the nutritional context. Nutr Rev (2010) 1.68
Choline deficiency in mice and humans is associated with increased plasma homocysteine concentration after a methionine load. Am J Clin Nutr (2005) 1.66
Clinical characteristics and pharmacokinetics of purified soy isoflavones: single-dose administration to healthy men. Am J Clin Nutr (2002) 1.60
Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency. FASEB J (2003) 1.59
Diethanolamine induces hepatic choline deficiency in mice. Toxicol Sci (2002) 1.57
Choline- and betaine-defined diets for use in clinical research and for the management of trimethylaminuria. J Am Diet Assoc (2004) 1.53
Choline metabolism and risk of breast cancer in a population-based study. FASEB J (2008) 1.51
Diethanolamine alters neurogenesis and induces apoptosis in fetal mouse hippocampus. FASEB J (2006) 1.47
Usual choline and betaine dietary intake and incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study. BMC Cardiovasc Disord (2007) 1.47
Elevated serum creatine phosphokinase in choline-deficient humans: mechanistic studies in C2C12 mouse myoblasts. Am J Clin Nutr (2004) 1.46
Nutrition education in U.S. medical schools: latest update of a national survey. Acad Med (2010) 1.42
Phosphatidylethanolamine N-methyltransferase (PEMT) gene expression is induced by estrogen in human and mouse primary hepatocytes. FASEB J (2007) 1.42
Perturbations in choline metabolism cause neural tube defects in mouse embryos in vitro. FASEB J (2002) 1.41
Status of nutrition education in medical schools. Am J Clin Nutr (2006) 1.41
Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas. J Biol Chem (2011) 1.40
Choline availability modulates human neuroblastoma cell proliferation and alters the methylation of the promoter region of the cyclin-dependent kinase inhibitor 3 gene. J Neurochem (2004) 1.40
Phosphatidylethanolamine-N-methyltransferase activity and dietary choline regulate liver-plasma lipid flux and essential fatty acid metabolism in mice. J Nutr (2003) 1.36
Folic acid deficiency during late gestation decreases progenitor cell proliferation and increases apoptosis in fetal mouse brain. J Nutr (2004) 1.35
Second trimester folate status and preterm birth. Am J Obstet Gynecol (2004) 1.32
Choline deficiency alters global histone methylation and epigenetic marking at the Re1 site of the calbindin 1 gene. FASEB J (2009) 1.21
Safety and pharmacokinetics of purified soy isoflavones: single-dose administration to postmenopausal women. Am J Clin Nutr (2002) 1.19
Metabolomic profiling can predict which humans will develop liver dysfunction when deprived of dietary choline. FASEB J (2010) 1.18
Choline deficiency increases lymphocyte apoptosis and DNA damage in humans. Am J Clin Nutr (2006) 1.18
BRCA1 promoter methylation is associated with increased mortality among women with breast cancer. Breast Cancer Res Treat (2008) 1.16
The association between betaine and choline intakes and the plasma concentrations of homocysteine in women. Am J Clin Nutr (2007) 1.16
Repeatability and measurement error in the assessment of choline and betaine dietary intake: the Atherosclerosis Risk in Communities (ARIC) study. Nutr J (2009) 1.16
Nutrition in medicine: nutrition education for medical students and residents. Nutr Clin Pract (2010) 1.14
Choline availability during embryonic development alters the localization of calretinin in developing and aging mouse hippocampus. Nutr Neurosci (2003) 1.10
Ad libitum choline intake in healthy individuals meets or exceeds the proposed adequate intake level. J Nutr (2005) 1.10
Maternal dietary choline deficiency alters angiogenesis in fetal mouse hippocampus. Proc Natl Acad Sci U S A (2010) 1.09
The role of dietary supplements during cancer therapy. J Nutr (2003) 1.09
Clinical characteristics and pharmacokinetics of purified soy isoflavones: multiple-dose administration to men with prostate neoplasia. Nutr Cancer (2004) 1.06
Maternal dietary choline availability alters the balance of netrin-1 and DCC neuronal migration proteins in fetal mouse brain hippocampus. Brain Res Dev Brain Res (2005) 1.06
Regulation of choline deficiency apoptosis by epidermal growth factor in CWSV-1 rat hepatocytes. Cell Physiol Biochem (2005) 1.05
Gene expression profiling of choline-deprived neural precursor cells isolated from mouse brain. Brain Res Mol Brain Res (2004) 1.04
Dietary isoflavones differentially induce gene expression changes in lymphocytes from postmenopausal women who form equol as compared with those who do not. J Nutr Biochem (2006) 1.04
Aberrant estrogen regulation of PEMT results in choline deficiency-associated liver dysfunction. J Biol Chem (2010) 1.04
GSTM1, GSTT1, GSTP1, and GSTA1 polymorphisms and urinary isothiocyanate metabolites following broccoli consumption in humans. J Nutr (2007) 1.03
Adverse event associated with methionine loading test: a case report. Arterioscler Thromb Vasc Biol (2002) 1.01
Alteration of bile acid metabolism in the rat induced by chronic ethanol consumption. FASEB J (2013) 1.00
High intakes of choline and betaine reduce breast cancer mortality in a population-based study. FASEB J (2009) 0.99
Deletion of murine choline dehydrogenase results in diminished sperm motility. FASEB J (2010) 0.99
Choline intake and genetic polymorphisms influence choline metabolite concentrations in human breast milk and plasma. Am J Clin Nutr (2010) 0.99
Mitochondrial and microsomal derived reactive oxygen species mediate apoptosis induced by transforming growth factor-beta1 in immortalized rat hepatocytes. J Cell Biochem (2003) 0.99
Computer-assisted teaching of nutritional anemias and diabetes to first-year medical students. Am J Clin Nutr (2002) 0.98
Lack of significant genotoxicity of purified soy isoflavones (genistein, daidzein, and glycitein) in 20 patients with prostate cancer. Am J Clin Nutr (2003) 0.98
Homocysteine metabolism in ZDF (type 2) diabetic rats. Diabetes (2005) 0.96
Deficiency in methionine, tryptophan, isoleucine, or choline induces apoptosis in cultured cells. J Nutr (2002) 0.95
Understanding the role of nutrition in the brain and behavioral development of toddlers and preschool children: identifying and addressing methodological barriers. Nutr Neurosci (2009) 0.95
The evolution of Nutrition in Medicine, a computer-assisted nutrition curriculum. Am J Clin Nutr (2006) 0.95
Deletion of the Pemt gene increases progenitor cell mitosis, DNA and protein methylation and decreases calretinin expression in embryonic day 17 mouse hippocampus. Brain Res Dev Brain Res (2004) 0.94
Adiponectin lowers glucose production by increasing SOGA. Am J Pathol (2010) 0.94
Phosphatidylcholine supplementation in pregnant women consuming moderate-choline diets does not enhance infant cognitive function: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr (2012) 0.92
Mouse betaine-homocysteine S-methyltransferase deficiency reduces body fat via increasing energy expenditure and impairing lipid synthesis and enhancing glucose oxidation in white adipose tissue. J Biol Chem (2012) 0.92
Inadequate intake of nutrients essential for neurodevelopment in children with fetal alcohol spectrum disorders (FASD). Neurotoxicol Teratol (2013) 0.92
Dietary choline requirements of women: effects of estrogen and genetic variation. Am J Clin Nutr (2010) 0.92
The epigenetic effects of a high prenatal folate intake in male mouse fetuses exposed in utero to arsenic. Toxicol Appl Pharmacol (2012) 0.91
Docosahexaenoic acid in plasma phosphatidylcholine may be a potential marker for in vivo phosphatidylethanolamine N-methyltransferase activity in humans. Am J Clin Nutr (2011) 0.91
Choline and betaine intake and the risk of colorectal cancer in men. Cancer Epidemiol Biomarkers Prev (2010) 0.90
Dietary docosahexaenoic acid supplementation modulates hippocampal development in the Pemt-/- mouse. J Biol Chem (2009) 0.90
Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. Nutr Res (2013) 0.90
Adapting the contents of computer-based instruction based on knowledge tests maintains effectiveness of nutrition education. Am J Clin Nutr (2003) 0.88
A targeted metabolomic protocol for short-chain fatty acids and branched-chain amino acids. Metabolomics (2013) 0.88
Dietary choline reverses some, but not all, effects of folate deficiency on neurogenesis and apoptosis in fetal mouse brain. J Nutr (2010) 0.87
Choline dehydrogenase polymorphism rs12676 is a functional variation and is associated with changes in human sperm cell function. PLoS One (2012) 0.87
Perspectives from the symposium: The role of nutrition in infant and toddler brain and behavioral development. Nutr Neurosci (2008) 0.85
Choline's role in maintaining liver function: new evidence for epigenetic mechanisms. Curr Opin Clin Nutr Metab Care (2013) 0.85
Genetic signatures in choline and 1-carbon metabolism are associated with the severity of hepatic steatosis. FASEB J (2013) 0.85
Are dietary choline and betaine intakes determinants of total homocysteine concentration? Am J Clin Nutr (2010) 0.85
Homocysteinemia in mice with genetic betaine homocysteine S-methyltransferase deficiency is independent of dietary folate intake. J Nutr (2012) 0.84
Lymphocyte gene expression in subjects fed a low-choline diet differs between those who develop organ dysfunction and those who do not. Am J Clin Nutr (2007) 0.84
Choline intake and risk of lethal prostate cancer: incidence and survival. Am J Clin Nutr (2012) 0.83
Effects of betaine in a murine model of mild cystathionine-beta-synthase deficiency. Metabolism (2004) 0.83
Effects of a high daily dose of soy isoflavones on DNA damage, apoptosis, and estrogenic outcomes in healthy postmenopausal women: a phase I clinical trial. Menopause (2008) 0.83
Choline: Dietary Requirements and Role in Brain Development. Nutr Today (2007) 0.82
Choline, homocysteine, and pregnancy. Am J Clin Nutr (2005) 0.82
Gene expression profiling in phosphatidylethanolamine N-methyltransferase knockout mice. Brain Res Mol Brain Res (2005) 0.82
Diethanolamine alters proliferation and choline metabolism in mouse neural precursor cells. Toxicol Sci (2007) 0.81
The betaine and choline content of a whole wheat flour compared to other mill streams. J Cereal Sci (2007) 0.79
Is there a new component of the Mediterranean diet that reduces inflammation? Am J Clin Nutr (2008) 0.77
Dose response effects of dermally applied diethanolamine on neurogenesis in fetal mouse hippocampus and potential exposure of humans. Toxicol Sci (2008) 0.76
The nutrigenetics and nutrigenomics of the dietary requirement for choline. Prog Mol Biol Transl Sci (2012) 0.76
The betaine content of sweat from adolescent females. J Int Soc Sports Nutr (2010) 0.76
Unexpected depletion in plasma choline and phosphatidylcholine concentrations in a pregnant woman with bipolar affective disorder being treated with lithuim, haloperidol and benztropine: a case report. J Med Case Rep (2008) 0.75