Published in Genetics on April 03, 2007
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A mouse diversity panel approach reveals the potential for clinical kidney injury due to DB289 not predicted by classical rodent models. Toxicol Sci (2012) 1.02
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Divergent and nonuniform gene expression patterns in mouse brain. Proc Natl Acad Sci U S A (2010) 0.97
Serious limitations of the QTL/microarray approach for QTL gene discovery. BMC Biol (2010) 0.95
Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity. Environ Health Perspect (2014) 0.94
A systems biology approach utilizing a mouse diversity panel identifies genetic differences influencing isoniazid-induced microvesicular steatosis. Toxicol Sci (2014) 0.92
Replication and narrowing of gene expression quantitative trait loci using inbred mice. Mamm Genome (2009) 0.92
Obesity genetics in mouse and human: back and forth, and back again. PeerJ (2015) 0.89
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In silico QTL mapping of basal liver iron levels in inbred mouse strains. Physiol Genomics (2010) 0.86
Genome wide analysis of inbred mouse lines identifies a locus containing Ppar-gamma as contributing to enhanced malaria survival. PLoS One (2010) 0.84
In silico QTL mapping of maternal nurturing ability with the mouse diversity panel. Physiol Genomics (2012) 0.83
Haplotype Association Mapping Identifies a Candidate Gene Region in Mice Infected With Staphylococcus aureus. G3 (Bethesda) (2012) 0.83
Variation and genetic control of gene expression in primary immunocytes across inbred mouse strains. J Immunol (2014) 0.83
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Methodologies for segregation analysis and QTL mapping in plants. Genetica (2008) 0.82
Fast and robust group-wise eQTL mapping using sparse graphical models. BMC Bioinformatics (2015) 0.79
Interindividual variation in epigenomic phenomena in humans. Mamm Genome (2009) 0.79
The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors. Sci Transl Med (2015) 0.78
Fidelity in Animal Modeling: Prerequisite for a Mechanistic Research Front Relevant to the Inflammatory Incompetence of Acute Pediatric Malnutrition. Int J Mol Sci (2016) 0.76
Sparse regression models for unraveling group and individual associations in eQTL mapping. BMC Bioinformatics (2016) 0.75
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Hypothalamic transcriptomes of 99 mouse strains reveal trans eQTL hotspots, splicing QTLs and novel non-coding genes. Elife (2016) 0.75
Integrated genomics of susceptibility to alkylator-induced leukemia in mice. BMC Genomics (2010) 0.75
Identifying genes that mediate anthracyline toxicity in immune cells. Front Pharmacol (2015) 0.75
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Genetic and genomic analysis of a fat mass trait with complex inheritance reveals marked sex specificity. PLoS Genet (2006) 3.51
A nonparametric test reveals selection for rapid flowering in the Arabidopsis genome. PLoS Biol (2006) 2.98
Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels. Genomics (2005) 2.61
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Coordinated transcription of key pathways in the mouse by the circadian clock. Cell (2002) 14.07
Obesity and metabolic syndrome in circadian Clock mutant mice. Science (2005) 12.66
PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues. Proc Natl Acad Sci U S A (2004) 12.43
BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources. Genome Biol (2009) 11.17
Discovery of gene function by expression profiling of the malaria parasite life cycle. Science (2003) 10.57
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Circadian integration of metabolism and energetics. Science (2010) 6.86
A gene wiki for community annotation of gene function. PLoS Biol (2008) 6.60
System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock. PLoS Biol (2007) 6.23
Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes. Nature (2010) 5.97
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol (2006) 5.83
The meter of metabolism. Cell (2008) 5.71
Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. Science (2010) 5.50
Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis. Science (2009) 5.30
High-fat diet disrupts behavioral and molecular circadian rhythms in mice. Cell Metab (2007) 4.93
Intercellular coupling confers robustness against mutations in the SCN circadian clock network. Cell (2007) 4.87
Temperature as a universal resetting cue for mammalian circadian oscillators. Science (2010) 4.85
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. Proc Natl Acad Sci U S A (2008) 4.80
Transcriptional architecture and chromatin landscape of the core circadian clock in mammals. Science (2012) 4.77
Central and peripheral circadian clocks in mammals. Annu Rev Neurosci (2012) 4.73
Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression. Curr Biol (2004) 4.49
Suprachiasmatic nucleus: cell autonomy and network properties. Annu Rev Physiol (2010) 4.38
Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening. Mol Cell (2003) 4.25
Melanopsin is required for non-image-forming photic responses in blind mice. Science (2003) 4.22
Use of a dense single nucleotide polymorphism map for in silico mapping in the mouse. PLoS Biol (2004) 4.08
cAMP-dependent signaling as a core component of the mammalian circadian pacemaker. Science (2008) 4.02
Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression. Cell (2007) 3.99
The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96
Genome-wide single-nucleotide polymorphism analysis defines haplotype patterns in mouse. Proc Natl Acad Sci U S A (2003) 3.93
Mania-like behavior induced by disruption of CLOCK. Proc Natl Acad Sci U S A (2007) 3.92
Complex Loci in human and mouse genomes. PLoS Genet (2006) 3.74
Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling. PLoS One (2008) 3.59
Expression analysis of G Protein-Coupled Receptors in mouse macrophages. Immunome Res (2008) 3.54
The Gene Wiki: community intelligence applied to human gene annotation. Nucleic Acids Res (2009) 3.51
Circadian timing of food intake contributes to weight gain. Obesity (Silver Spring) (2009) 3.44
Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1. Nature (2008) 3.39
A genome-wide RNAi screen for modifiers of the circadian clock in human cells. Cell (2009) 3.27
Genome-wide analysis of CREB target genes reveals a core promoter requirement for cAMP responsiveness. Mol Cell (2003) 3.23
Activity of IPI-504, a novel heat-shock protein 90 inhibitor, in patients with molecularly defined non-small-cell lung cancer. J Clin Oncol (2010) 3.15
The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations. Proc Natl Acad Sci U S A (2008) 3.13
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery. Science (2011) 3.07
Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation. Proc Natl Acad Sci U S A (2007) 3.06
In situ proteolysis for protein crystallization and structure determination. Nat Methods (2007) 3.05
Regulation of dopaminergic transmission and cocaine reward by the Clock gene. Proc Natl Acad Sci U S A (2005) 2.95
A systematic map of genetic variation in Plasmodium falciparum. PLoS Pathog (2006) 2.92
Genetics of circadian rhythms in Mammalian model organisms. Adv Genet (2011) 2.80
Mouse proteome analysis. Genome Res (2003) 2.69
A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo. Proc Natl Acad Sci U S A (2005) 2.67
Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. Nature (2012) 2.67
Genetical genomics: spotlight on QTL hotspots. PLoS Genet (2008) 2.63
Circadian rhythms, sleep, and metabolism. J Clin Invest (2011) 2.60
Illumination of the melanopsin signaling pathway. Science (2005) 2.58
BioGPS and MyGene.info: organizing online, gene-centric information. Nucleic Acids Res (2012) 2.57
An efficient rapid system for profiling the cellular activities of molecular libraries. Proc Natl Acad Sci U S A (2006) 2.51
Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice. Science (2013) 2.49
A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy. Nat Commun (2010) 2.49
Circadian rhythms and metabolic syndrome: from experimental genetics to human disease. Circ Res (2010) 2.49
Transcript annotation in FANTOM3: mouse gene catalog based on physical cDNAs. PLoS Genet (2006) 2.48
Predictors of medication adherence in inflammatory bowel disease. Am J Gastroenterol (2007) 2.46
SQ109 targets MmpL3, a membrane transporter of trehalose monomycolate involved in mycolic acid donation to the cell wall core of Mycobacterium tuberculosis. Antimicrob Agents Chemother (2012) 2.41
Dissecting the functions of the mammalian clock protein BMAL1 by tissue-specific rescue in mice. Science (2006) 2.41
The mouse Clock mutation reduces circadian pacemaker amplitude and enhances efficacy of resetting stimuli and phase-response curve amplitude. Proc Natl Acad Sci U S A (2006) 2.36
Kidney transplant rejection and tissue injury by gene profiling of biopsies and peripheral blood lymphocytes. Am J Transplant (2004) 2.35
Gene set enrichment in eQTL data identifies novel annotations and pathway regulators. PLoS Genet (2008) 2.32