Published in J Virol on May 28, 2014
Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma. Proc Natl Acad Sci U S A (1980) 30.08
The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins. Science (1988) 27.01
Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor. Cell (1987) 20.61
Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease. Proc Natl Acad Sci U S A (1982) 12.84
Type C virus particles in a cord T-cell line derived by co-cultivating normal human cord leukocytes and human leukaemic T cells. Nature (1981) 9.25
Evidence that the leucine zipper is a coiled coil. Science (1989) 8.00
The role of the leucine zipper in the fos-jun interaction. Nature (1988) 7.44
c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities. Cell (1988) 6.24
AP-1 in cell proliferation and survival. Oncogene (2001) 6.07
Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation. Nat Rev Cancer (2007) 4.69
Isolation of a new type C retrovirus (HTLV) in primary uncultured cells of a patient with Sézary T-cell leukaemia. Nature (1981) 4.38
Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain. Nature (1988) 3.43
HTLV-I basic leucine zipper factor gene mRNA supports proliferation of adult T cell leukemia cells. Proc Natl Acad Sci U S A (2006) 3.11
Heterodimer formation between CREB and JUN proteins. Oncogene (1990) 3.04
The complementary strand of the human T-cell leukemia virus type 1 RNA genome encodes a bZIP transcription factor that down-regulates viral transcription. J Virol (2002) 3.01
Emergence of unique primate T-lymphotropic viruses among central African bushmeat hunters. Proc Natl Acad Sci U S A (2005) 2.86
Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I. Proc Natl Acad Sci U S A (1995) 2.43
Molecular mechanisms of human T-cell leukemia/lymphotropic virus type I infection. Blood (1995) 2.19
Fos-Jun interaction: mutational analysis of the leucine zipper domain of both proteins. Genes Dev (1989) 2.06
The HBZ factor of human T-cell leukemia virus type I dimerizes with transcription factors JunB and c-Jun and modulates their transcriptional activity. J Biol Chem (2003) 2.02
Enhancement of infectivity and persistence in vivo by HBZ, a natural antisense coded protein of HTLV-1. Blood (2006) 1.98
Long-term increases in lymphocytes and platelets in human T-lymphotropic virus type II infection. Blood (2008) 1.88
HTLV-I antisense transcripts initiating in the 3'LTR are alternatively spliced and polyadenylated. Retrovirology (2006) 1.87
Abundant tax protein expression in CD4+ T cells infected with human T-cell lymphotropic virus type I (HTLV-I) is prevented by cytotoxic T lymphocytes. Blood (2000) 1.87
Constitutive activation of NF-kappa B is essential for transformation of rat fibroblasts by the human T-cell leukemia virus type I Tax protein. EMBO J (1996) 1.85
Comparative biology of human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2. Oncogene (2005) 1.73
Discovery of a new human T-cell lymphotropic virus (HTLV-3) in Central Africa. Retrovirology (2005) 1.70
HTLV-1 HBZ suppresses AP-1 activity by impairing both the DNA-binding ability and the stability of c-Jun protein. Oncogene (2005) 1.66
Human T-cell leukemia virus type-1 antisense-encoded gene, Hbz, promotes T-lymphocyte proliferation. Blood (2008) 1.63
Human T-cell leukemia virus type 1 (HTLV-1) bZIP protein interacts with the cellular transcription factor CREB to inhibit HTLV-1 transcription. J Virol (2006) 1.63
HBZ interacts with JunD and stimulates its transcriptional activity. FEBS Lett (2004) 1.63
In vivo expression of the HBZ gene of HTLV-1 correlates with proviral load, inflammatory markers and disease severity in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). Retrovirology (2009) 1.58
A novel alternative splicing isoform of human T-cell leukemia virus type 1 bZIP factor (HBZ-SI) targets distinct subnuclear localization. J Virol (2006) 1.58
Human T-cell leukemia virus type 1 bZIP factor selectively suppresses the classical pathway of NF-kappaB. Blood (2008) 1.55
HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo. PLoS Pathog (2011) 1.53
Molecular and cellular aspects of HTLV-1 associated leukemogenesis in vivo. Leukemia (2003) 1.39
An interaction between the human T cell leukemia virus type 1 basic leucine zipper factor (HBZ) and the KIX domain of p300/CBP contributes to the down-regulation of tax-dependent viral transcription by HBZ. J Biol Chem (2008) 1.34
Human T-lymphotropic virus type II and neurological disease. Ann Neurol (2004) 1.32
Function of AP-1 in transcription of the telomerase reverse transcriptase gene (TERT) in human and mouse cells. Mol Cell Biol (2005) 1.31
HTLV-1 HBZ cooperates with JunD to enhance transcription of the human telomerase reverse transcriptase gene (hTERT). Retrovirology (2007) 1.29
HBZ, a new important player in the mystery of adult T-cell leukemia. Blood (2006) 1.27
The HBZ-SP1 isoform of human T-cell leukemia virus type I represses JunB activity by sequestration into nuclear bodies. Retrovirology (2007) 1.18
Ancient, independent evolution and distinct molecular features of the novel human T-lymphotropic virus type 4. Retrovirology (2009) 1.16
Human T-cell lymphotropic virus type 3: complete nucleotide sequence and characterization of the human tax3 protein. J Virol (2006) 1.11
Ancient origin and molecular features of the novel human T-lymphotropic virus type 3 revealed by complete genome analysis. J Virol (2006) 1.10
Activation of E2F-mediated transcription by human T-cell leukemia virus type I Tax protein in a p16(INK4A)-negative T-cell line. J Biol Chem (1998) 1.08
A modified version of a Fos-associated cluster in HBZ affects Jun transcriptional potency. Nucleic Acids Res (2006) 1.02
Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays. Biochemistry (2010) 1.00
Brain tumours and lymphomas in transgenic mice that carry HTLV-I LTR/c-myc and Ig/tax genes. Oncogene (1992) 0.98
Distinct transformation tropism exhibited by human T lymphotropic virus type 1 (HTLV-1) and HTLV-2 is the result of postinfection T cell clonal expansion. J Virol (2012) 0.96
fos and jun interaction: the role of the leucine zipper. Int J Cancer Suppl (1989) 0.95
Atypical bZIP domain of viral transcription factor contributes to stability of dimer formation and transcriptional function. J Virol (2007) 0.95
Molecular mechanism of tumorigenesis in mice transgenic for the human T cell leukemia virus Tax gene. Virology (1998) 0.95
Human T-cell leukemia virus type 1 HBZ protein bypasses the targeting function of ubiquitination. J Biol Chem (2008) 0.94
Propensity for HBZ-SP1 isoform of HTLV-I to inhibit c-Jun activity correlates with sequestration of c-Jun into nuclear bodies rather than inhibition of its DNA-binding activity. Virology (2009) 0.92
Human T-cell leukemia virus type 1 (HTLV-1) bZIP factor requires cellular transcription factor JunD to upregulate HTLV-1 antisense transcription from the 3' long terminal repeat. J Virol (2012) 0.92
HTLV-2 APH-2 expression is correlated with proviral load but APH-2 does not promote lymphocytosis. J Infect Dis (2011) 0.91
Short communication: Absence of evidence of HTLV-3 and HTLV-4 in patients with large granular lymphocyte (LGL) leukemia. AIDS Res Hum Retroviruses (2008) 0.89
New insight into the oncogenic mechanism of the retroviral oncoprotein Tax. Protein Cell (2012) 0.87
Does the HBZ gene represent a new potential target for the treatment of adult T-cell leukemia? Int Rev Immunol (2007) 0.87
HTLV-1 basic leucine-zipper factor, HBZ, interacts with MafB and suppresses transcription through a Maf recognition element. J Cell Biochem (2010) 0.85
The transcription profile of Tax-3 is more similar to Tax-1 than Tax-2: insights into HTLV-3 potential leukemogenic properties. PLoS One (2012) 0.85
Interplay between the HTLV-2 Tax and APH-2 proteins in the regulation of the AP-1 pathway. Retrovirology (2012) 0.84
Human T-cell leukemia virus type 2 antisense viral protein 2 is dispensable for in vitro immortalization but functions to repress early virus replication in vivo. J Virol (2012) 0.83
LGL leukemia and HTLV. AIDS Res Hum Retroviruses (2010) 0.83
Negative regulation of the NFAT1 factor by CD45: implication in HIV-1 long terminal repeat activation. J Immunol (2001) 0.81
Temporal regulation of HTLV-2 expression in infected cell lines and patients: evidence for distinct expression kinetics with nuclear accumulation of APH-2 mRNA. Retrovirology (2012) 0.81