Jeffrey A Kline

Author PubWeight™ 140.29‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial. JAMA 2010 8.09
2 Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension: a scientific statement from the American Heart Association. Circulation 2011 5.16
3 Prospective external validation of the clinical effectiveness of an emergency department-based early goal-directed therapy protocol for severe sepsis and septic shock. Chest 2007 4.60
4 Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol. Crit Care Med 2011 3.82
5 The effect of a quantitative resuscitation strategy on mortality in patients with sepsis: a meta-analysis. Crit Care Med 2008 3.73
6 2-Hour accelerated diagnostic protocol to assess patients with chest pain symptoms using contemporary troponins as the only biomarker: the ADAPT trial. J Am Coll Cardiol 2012 3.15
7 Randomized, controlled trial of immediate versus delayed goal-directed ultrasound to identify the cause of nontraumatic hypotension in emergency department patients. Crit Care Med 2004 3.12
8 The Sequential Organ Failure Assessment score for predicting outcome in patients with severe sepsis and evidence of hypoperfusion at the time of emergency department presentation. Crit Care Med 2009 2.92
9 Determination of left ventricular function by emergency physician echocardiography of hypotensive patients. Acad Emerg Med 2002 2.35
10 Echocardiographic and functional cardiopulmonary problems 6 months after first-time pulmonary embolism in previously healthy patients. Eur Heart J 2007 2.26
11 Emergency department hypotension predicts sudden unexpected in-hospital mortality: a prospective cohort study. Chest 2006 2.22
12 Whole blood lactate kinetics in patients undergoing quantitative resuscitation for severe sepsis and septic shock. Chest 2013 2.20
13 Comprehensive standardized data definitions for acute coronary syndrome research in emergency departments in Australasia. Emerg Med Australas 2010 2.19
14 The chest pain choice decision aid: a randomized trial. Circ Cardiovasc Qual Outcomes 2012 2.15
15 Evaluation of pulmonary embolism in the emergency department and consistency with a national quality measure: quantifying the opportunity for improvement. Arch Intern Med 2012 2.15
16 Use of goal-directed therapy for severe sepsis and septic shock in academic emergency departments. Crit Care Med 2005 2.03
17 Factors associated with positive D-dimer results in patients evaluated for pulmonary embolism. Acad Emerg Med 2010 1.95
18 Outcomes of patients undergoing early sepsis resuscitation for cryptic shock compared with overt shock. Resuscitation 2011 1.87
19 Incidence of contrast-induced nephropathy after contrast-enhanced computed tomography in the outpatient setting. Clin J Am Soc Nephrol 2009 1.74
20 Operational performance of validated physiologic scoring systems for predicting in-hospital mortality among critically ill emergency department patients. Crit Care Med 2005 1.72
21 Risk of thromboembolism varies, depending on category of immobility in outpatients. Ann Emerg Med 2009 1.71
22 Performance of the Mortality in Emergency Department Sepsis score for predicting hospital mortality among patients with severe sepsis and septic shock. Am J Emerg Med 2008 1.66
23 Cost-effectiveness of an emergency department-based early sepsis resuscitation protocol. Crit Care Med 2011 1.65
24 Immediate complications of intravenous contrast for computed tomography imaging in the outpatient setting are rare. Acad Emerg Med 2011 1.59
25 One year mortality of patients treated with an emergency department based early goal directed therapy protocol for severe sepsis and septic shock: a before and after study. Crit Care 2009 1.57
26 Systematic review of emergency physician-performed ultrasonography for lower-extremity deep vein thrombosis. Acad Emerg Med 2008 1.49
27 Procalcitonin test in the diagnosis of bacteremia: a meta-analysis. Ann Emerg Med 2006 1.49
28 Nontraumatic out-of-hospital hypotension predicts inhospital mortality. Ann Emerg Med 2004 1.44
29 Pulmonary vascular reserve during experimental pulmonary embolism: effects of a soluble guanylate cyclase stimulator, BAY 41-8543. Crit Care Med 2011 1.43
30 Prevalence and significance of nonthromboembolic findings on chest computed tomography angiography performed to rule out pulmonary embolism: a multicenter study of 1,025 emergency department patients. Acad Emerg Med 2004 1.43
31 Clinical features from the history and physical examination that predict the presence or absence of pulmonary embolism in symptomatic emergency department patients: results of a prospective, multicenter study. Ann Emerg Med 2010 1.37
32 Focused training of emergency medicine residents in goal-directed echocardiography: a prospective study. Acad Emerg Med 2003 1.31
33 Prognostic value and agreement of achieving lactate clearance or central venous oxygen saturation goals during early sepsis resuscitation. Acad Emerg Med 2012 1.24
34 Systematic bias introduced by the informed consent process in a diagnostic research study. Acad Emerg Med 2008 1.21
35 High discordance of chest x-ray and computed tomography for detection of pulmonary opacities in ED patients: implications for diagnosing pneumonia. Am J Emerg Med 2012 1.21
36 Clinical characteristics, management, and outcomes of patients diagnosed with acute pulmonary embolism in the emergency department: initial report of EMPEROR (Multicenter Emergency Medicine Pulmonary Embolism in the Real World Registry). J Am Coll Cardiol 2011 1.19
37 Bench to bedside: the role of mitochondrial medicine in the pathogenesis and treatment of cellular injury. Acad Emerg Med 2003 1.17
38 Severity of emergency department hypotension predicts adverse hospital outcome. Shock 2004 1.16
39 Chemokines accumulate in the lungs of rats with severe pulmonary embolism induced by polystyrene microspheres. J Immunol 2003 1.11
40 Further illumination of the test threshold approach in the care of emergency department patients with symptoms of pulmonary embolism. Ann Emerg Med 2010 1.09
41 Emergency medicine practitioner knowledge and use of decision rules for the evaluation of patients with suspected pulmonary embolism: variations by practice setting and training level. Acad Emerg Med 2006 1.06
42 Clinical features of patients with pulmonary embolism and a negative PERC rule result. Ann Emerg Med 2013 1.05
43 Prospective study of the incidence of contrast-induced nephropathy among patients evaluated for pulmonary embolism by contrast-enhanced computed tomography. Acad Emerg Med 2012 1.04
44 Prospective, randomized evaluation of a personal digital assistant-based research tool in the emergency department. BMC Med Inform Decis Mak 2008 1.03
45 Intraobserver and interobserver agreement of the interpretation of pediatric chest radiographs. Emerg Radiol 2010 1.02
46 Predictors of the complication of postintubation hypotension during emergency airway management. J Crit Care 2012 1.02
47 Cardiac inflammation contributes to right ventricular dysfunction following experimental pulmonary embolism in rats. J Mol Cell Cardiol 2006 1.01
48 Emergency echocardiography to detect pericardial effusion in patients in PEA and near-PEA states. Resuscitation 2003 0.97
49 Determination of the effect of in vitro time, temperature, and tourniquet use on whole blood venous point-of-care lactate concentrations. Acad Emerg Med 2007 0.97
50 Comparison of the unstructured clinician estimate of pretest probability for pulmonary embolism to the Canadian score and the Charlotte rule: a prospective observational study. Acad Emerg Med 2005 0.97
51 Diagnostic accuracy of left ventricular function for identifying sepsis among emergency department patients with nontraumatic symptomatic undifferentiated hypotension. Shock 2005 0.97
52 The significance of non-sustained hypotension in emergency department patients with sepsis. Intensive Care Med 2009 0.97
53 The frequency and significance of postintubation hypotension during emergency airway management. J Crit Care 2011 0.97
54 Prospective multicenter study of quantitative pretest probability assessment to exclude acute coronary syndrome for patients evaluated in emergency department chest pain units. Ann Emerg Med 2006 0.94
55 The Chest Pain Choice trial: a pilot randomized trial of a decision aid for patients with chest pain in the emergency department. Trials 2010 0.93
56 Inhibition of prostaglandin synthesis during polystyrene microsphere-induced pulmonary embolism in the rat. Am J Physiol Lung Cell Mol Physiol 2003 0.93
57 Characteristics and outcomes of patients with vasoplegic versus tissue dysoxic septic shock. Shock 2013 0.91
58 Potential impact of adjusting the threshold of the quantitative D-dimer based on pretest probability of acute pulmonary embolism. Acad Emerg Med 2009 0.91
59 Interobserver agreement for the diagnosis of venous thromboembolism on computed tomography chest angiography and indirect venography of the lower extremities in emergency department patients. Acad Emerg Med 2006 0.91
60 Emergency department resuscitative procedures: animal laboratory training improves procedural competency and speed. Acad Emerg Med 2002 0.89
61 Plasma levels of mitochondrial DNA in patients presenting to the emergency department with sepsis. Shock 2012 0.89
62 End tidal CO(2) is reduced during hypotension and cardiac arrest in a rat model of massive pulmonary embolism. Resuscitation 2002 0.87
63 Development and comparison of a minimally-invasive model of autologous clot pulmonary embolism in Sprague-Dawley and Copenhagen rats. Thromb J 2010 0.86
64 Therapy and outcomes in massive pulmonary embolism from the Emergency Medicine Pulmonary Embolism in the Real World Registry. Am J Emerg Med 2012 0.86
65 Frequency of thrombophilia-related genetic variations in patients with idiopathic pulmonary embolism in an urban emergency department. Clin Chem 2006 0.85
66 Proteomics of microparticles after experimental pulmonary embolism. Thromb Res 2011 0.85
67 Multimarker panel to rule out acute coronary syndromes in low-risk patients. Acad Emerg Med 2006 0.85
68 Estimating the pretest probability threshold to justify empiric administration of heparin prior to pulmonary vascular imaging for pulmonary embolism. Thromb Res 2005 0.84
69 Effect of glucose-insulin-potassium infusion on mortality in critical care settings: a systematic review and meta-analysis. J Clin Pharmacol 2009 0.84
70 Inhibition of CINC-1 decreases right ventricular damage caused by experimental pulmonary embolism in rats. J Immunol 2007 0.84
71 Right ventricular heart failure from pulmonary embolism: key distinctions from chronic pulmonary hypertension. J Card Fail 2010 0.84
72 12-lead ECG findings of pulmonary hypertension occur more frequently in emergency department patients with pulmonary embolism than in patients without pulmonary embolism. Ann Emerg Med 2009 0.83
73 Transcriptional profile of right ventricular tissue during acute pulmonary embolism in rats. Physiol Genomics 2008 0.83
74 Arginase depletes plasma l-arginine and decreases pulmonary vascular reserve during experimental pulmonary embolism. Pulm Pharmacol Ther 2011 0.82
75 Effectiveness of the Chest Pain Choice decision aid in emergency department patients with low-risk chest pain: study protocol for a multicenter randomized trial. Trials 2014 0.82
76 Up-regulation of arginase II contributes to pulmonary vascular endothelial cell dysfunction during experimental pulmonary embolism. Pulm Pharmacol Ther 2011 0.81
77 Cardiac UCP2 expression and myocardial oxidative metabolism during acute septic shock in the rat. Shock 2003 0.80
78 Prospective use of a clinical decision rule to identify pulmonary embolism as likely cause of outpatient cardiac arrest. Resuscitation 2005 0.80
79 Transcriptional changes in right ventricular tissues are enriched in the outflow tract compared with the apex during chronic pulmonary embolism in rats. Physiol Genomics 2009 0.80
80 Evaluation of capnography using a genetic algorithm to predict PaCO2. Chest 2005 0.79
81 Contribution of fibrinolysis to the physical component summary of the SF-36 after acute submassive pulmonary embolism. J Thromb Thrombolysis 2015 0.79
82 Lack of association between prehospital response times and patient outcomes. Prehosp Emerg Care 2009 0.79
83 Venous thromboembolism: EINSTEIN transforms anticoagulant therapy in acute PE. Nat Rev Cardiol 2012 0.79
84 Prognostic value of incremental lactate elevations in emergency department patients with suspected infection. Acad Emerg Med 2012 0.79
85 Fatal pulmonary embolism immediately after transatlantic air travel to the United States: less than one in a million. Thromb Haemost 2002 0.78
86 Direct comparison of the diagnostic accuracy of fifty protein biological markers of pulmonary embolism for use in the emergency department. Acad Emerg Med 2008 0.78
87 The art and science of probabilistic decision-making in emergency medicine. Acad Emerg Med 2010 0.78
88 Dichloroacetate increases skeletal muscle pyruvate dehydrogenase activity during acute limb ischemia. Vasc Endovascular Surg 2003 0.78
89 Association of body mass index with increased cost of care and length of stay for emergency department patients with chest pain and dyspnea. Circ Cardiovasc Qual Outcomes 2014 0.78
90 Contrast-induced nephropathy: doubts and certainties. Acad Emerg Med 2012 0.78
91 Proinflammatory events in right ventricular damage during pulmonary embolism: effects of treatment with ketorolac in rats. J Cardiovasc Pharmacol 2009 0.77
92 The effects of dichloroacetate in a rabbit model of acute hind-limb ischemia and reperfusion. J Am Coll Surg 2003 0.77
93 The beneficial effects of dichloroacetate in acute limb ischemia. Mil Med 2007 0.76
94 Tandem measurement of D-dimer and myeloperoxidase or C-reactive protein to effectively screen for pulmonary embolism in the emergency department. Acad Emerg Med 2008 0.76
95 A soluble guanylate cyclase stimulator, BAY 41-8543, preserves right ventricular function in experimental pulmonary embolism. Pulm Pharmacol Ther 2012 0.76
96 Diagnosing pulmonary embolism in the emergency department: maybe we do matter, after all. Emerg Med Australas 2009 0.75
97 Serial Procalcitonin Predicts Mortality in Severe Sepsis Patients: Results From the Multicenter Procalcitonin MOnitoring SEpsis (MOSES) Study. Crit Care Med 2017 0.75
98 Risk stratification of community-acquired pneumonia: what does all of this mean? Ann Emerg Med 2008 0.75
99 More on the PERC rule. Ann Emerg Med 2012 0.75
100 A primer on the complicated subject of cost-effectiveness analyses for pulmonary embolism. Ann Emerg Med 2010 0.75
101 Making the black box more useful. Emerg Med J 2014 0.75
102 Pleural effusions in the critically ill: the evolving role of bedside ultrasound. Crit Care Med 2005 0.75
103 Crash course in decision making. Acad Emerg Med 2004 0.75
104 Save the beans. Ann Emerg Med 2010 0.75
105 End expiratory oxygen concentrations to predict central venous oxygen saturation: an observational pilot study. BMC Emerg Med 2006 0.75
106 Computed tomography in the emergency department setting--reply. JAMA Intern Med 2013 0.75
107 Elevated brain natriuretic peptide in septic patients without heart failure. Ann Emerg Med 2003 0.75
108 Frequency of thromboprophylaxis and incidence of in-hospital venous thromboembolism in a cohort of emergency department patients. J Thromb Thrombolysis 2007 0.75
109 Research priorities for the influence of gender on diagnostic imaging choices in the emergency department setting. Acad Emerg Med 2014 0.75
110 Comparison of acute and convalescent biomarkers of inflammation in patients with acute pulmonary embolism treated with systemic fibrinolysis vs. placebo. Blood Coagul Fibrinolysis 2017 0.75
111 Indirect computed tomography venography: a report of vascular opacification. Emerg Radiol 2010 0.75