| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial.
|
JAMA
|
2010
|
8.09
|
|
2
|
Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension: a scientific statement from the American Heart Association.
|
Circulation
|
2011
|
5.16
|
|
3
|
Prospective external validation of the clinical effectiveness of an emergency department-based early goal-directed therapy protocol for severe sepsis and septic shock.
|
Chest
|
2007
|
4.60
|
|
4
|
Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol.
|
Crit Care Med
|
2011
|
3.82
|
|
5
|
The effect of a quantitative resuscitation strategy on mortality in patients with sepsis: a meta-analysis.
|
Crit Care Med
|
2008
|
3.73
|
|
6
|
2-Hour accelerated diagnostic protocol to assess patients with chest pain symptoms using contemporary troponins as the only biomarker: the ADAPT trial.
|
J Am Coll Cardiol
|
2012
|
3.15
|
|
7
|
Randomized, controlled trial of immediate versus delayed goal-directed ultrasound to identify the cause of nontraumatic hypotension in emergency department patients.
|
Crit Care Med
|
2004
|
3.12
|
|
8
|
The Sequential Organ Failure Assessment score for predicting outcome in patients with severe sepsis and evidence of hypoperfusion at the time of emergency department presentation.
|
Crit Care Med
|
2009
|
2.92
|
|
9
|
Determination of left ventricular function by emergency physician echocardiography of hypotensive patients.
|
Acad Emerg Med
|
2002
|
2.35
|
|
10
|
Echocardiographic and functional cardiopulmonary problems 6 months after first-time pulmonary embolism in previously healthy patients.
|
Eur Heart J
|
2007
|
2.26
|
|
11
|
Emergency department hypotension predicts sudden unexpected in-hospital mortality: a prospective cohort study.
|
Chest
|
2006
|
2.22
|
|
12
|
Whole blood lactate kinetics in patients undergoing quantitative resuscitation for severe sepsis and septic shock.
|
Chest
|
2013
|
2.20
|
|
13
|
Comprehensive standardized data definitions for acute coronary syndrome research in emergency departments in Australasia.
|
Emerg Med Australas
|
2010
|
2.19
|
|
14
|
The chest pain choice decision aid: a randomized trial.
|
Circ Cardiovasc Qual Outcomes
|
2012
|
2.15
|
|
15
|
Evaluation of pulmonary embolism in the emergency department and consistency with a national quality measure: quantifying the opportunity for improvement.
|
Arch Intern Med
|
2012
|
2.15
|
|
16
|
Use of goal-directed therapy for severe sepsis and septic shock in academic emergency departments.
|
Crit Care Med
|
2005
|
2.03
|
|
17
|
Factors associated with positive D-dimer results in patients evaluated for pulmonary embolism.
|
Acad Emerg Med
|
2010
|
1.95
|
|
18
|
Outcomes of patients undergoing early sepsis resuscitation for cryptic shock compared with overt shock.
|
Resuscitation
|
2011
|
1.87
|
|
19
|
Incidence of contrast-induced nephropathy after contrast-enhanced computed tomography in the outpatient setting.
|
Clin J Am Soc Nephrol
|
2009
|
1.74
|
|
20
|
Operational performance of validated physiologic scoring systems for predicting in-hospital mortality among critically ill emergency department patients.
|
Crit Care Med
|
2005
|
1.72
|
|
21
|
Risk of thromboembolism varies, depending on category of immobility in outpatients.
|
Ann Emerg Med
|
2009
|
1.71
|
|
22
|
Performance of the Mortality in Emergency Department Sepsis score for predicting hospital mortality among patients with severe sepsis and septic shock.
|
Am J Emerg Med
|
2008
|
1.66
|
|
23
|
Cost-effectiveness of an emergency department-based early sepsis resuscitation protocol.
|
Crit Care Med
|
2011
|
1.65
|
|
24
|
Immediate complications of intravenous contrast for computed tomography imaging in the outpatient setting are rare.
|
Acad Emerg Med
|
2011
|
1.59
|
|
25
|
One year mortality of patients treated with an emergency department based early goal directed therapy protocol for severe sepsis and septic shock: a before and after study.
|
Crit Care
|
2009
|
1.57
|
|
26
|
Systematic review of emergency physician-performed ultrasonography for lower-extremity deep vein thrombosis.
|
Acad Emerg Med
|
2008
|
1.49
|
|
27
|
Procalcitonin test in the diagnosis of bacteremia: a meta-analysis.
|
Ann Emerg Med
|
2006
|
1.49
|
|
28
|
Nontraumatic out-of-hospital hypotension predicts inhospital mortality.
|
Ann Emerg Med
|
2004
|
1.44
|
|
29
|
Pulmonary vascular reserve during experimental pulmonary embolism: effects of a soluble guanylate cyclase stimulator, BAY 41-8543.
|
Crit Care Med
|
2011
|
1.43
|
|
30
|
Prevalence and significance of nonthromboembolic findings on chest computed tomography angiography performed to rule out pulmonary embolism: a multicenter study of 1,025 emergency department patients.
|
Acad Emerg Med
|
2004
|
1.43
|
|
31
|
Clinical features from the history and physical examination that predict the presence or absence of pulmonary embolism in symptomatic emergency department patients: results of a prospective, multicenter study.
|
Ann Emerg Med
|
2010
|
1.37
|
|
32
|
Focused training of emergency medicine residents in goal-directed echocardiography: a prospective study.
|
Acad Emerg Med
|
2003
|
1.31
|
|
33
|
Prognostic value and agreement of achieving lactate clearance or central venous oxygen saturation goals during early sepsis resuscitation.
|
Acad Emerg Med
|
2012
|
1.24
|
|
34
|
Systematic bias introduced by the informed consent process in a diagnostic research study.
|
Acad Emerg Med
|
2008
|
1.21
|
|
35
|
High discordance of chest x-ray and computed tomography for detection of pulmonary opacities in ED patients: implications for diagnosing pneumonia.
|
Am J Emerg Med
|
2012
|
1.21
|
|
36
|
Clinical characteristics, management, and outcomes of patients diagnosed with acute pulmonary embolism in the emergency department: initial report of EMPEROR (Multicenter Emergency Medicine Pulmonary Embolism in the Real World Registry).
|
J Am Coll Cardiol
|
2011
|
1.19
|
|
37
|
Bench to bedside: the role of mitochondrial medicine in the pathogenesis and treatment of cellular injury.
|
Acad Emerg Med
|
2003
|
1.17
|
|
38
|
Severity of emergency department hypotension predicts adverse hospital outcome.
|
Shock
|
2004
|
1.16
|
|
39
|
Chemokines accumulate in the lungs of rats with severe pulmonary embolism induced by polystyrene microspheres.
|
J Immunol
|
2003
|
1.11
|
|
40
|
Further illumination of the test threshold approach in the care of emergency department patients with symptoms of pulmonary embolism.
|
Ann Emerg Med
|
2010
|
1.09
|
|
41
|
Emergency medicine practitioner knowledge and use of decision rules for the evaluation of patients with suspected pulmonary embolism: variations by practice setting and training level.
|
Acad Emerg Med
|
2006
|
1.06
|
|
42
|
Clinical features of patients with pulmonary embolism and a negative PERC rule result.
|
Ann Emerg Med
|
2013
|
1.05
|
|
43
|
Prospective study of the incidence of contrast-induced nephropathy among patients evaluated for pulmonary embolism by contrast-enhanced computed tomography.
|
Acad Emerg Med
|
2012
|
1.04
|
|
44
|
Prospective, randomized evaluation of a personal digital assistant-based research tool in the emergency department.
|
BMC Med Inform Decis Mak
|
2008
|
1.03
|
|
45
|
Intraobserver and interobserver agreement of the interpretation of pediatric chest radiographs.
|
Emerg Radiol
|
2010
|
1.02
|
|
46
|
Predictors of the complication of postintubation hypotension during emergency airway management.
|
J Crit Care
|
2012
|
1.02
|
|
47
|
Cardiac inflammation contributes to right ventricular dysfunction following experimental pulmonary embolism in rats.
|
J Mol Cell Cardiol
|
2006
|
1.01
|
|
48
|
Emergency echocardiography to detect pericardial effusion in patients in PEA and near-PEA states.
|
Resuscitation
|
2003
|
0.97
|
|
49
|
Determination of the effect of in vitro time, temperature, and tourniquet use on whole blood venous point-of-care lactate concentrations.
|
Acad Emerg Med
|
2007
|
0.97
|
|
50
|
Comparison of the unstructured clinician estimate of pretest probability for pulmonary embolism to the Canadian score and the Charlotte rule: a prospective observational study.
|
Acad Emerg Med
|
2005
|
0.97
|
|
51
|
Diagnostic accuracy of left ventricular function for identifying sepsis among emergency department patients with nontraumatic symptomatic undifferentiated hypotension.
|
Shock
|
2005
|
0.97
|
|
52
|
The significance of non-sustained hypotension in emergency department patients with sepsis.
|
Intensive Care Med
|
2009
|
0.97
|
|
53
|
The frequency and significance of postintubation hypotension during emergency airway management.
|
J Crit Care
|
2011
|
0.97
|
|
54
|
Prospective multicenter study of quantitative pretest probability assessment to exclude acute coronary syndrome for patients evaluated in emergency department chest pain units.
|
Ann Emerg Med
|
2006
|
0.94
|
|
55
|
The Chest Pain Choice trial: a pilot randomized trial of a decision aid for patients with chest pain in the emergency department.
|
Trials
|
2010
|
0.93
|
|
56
|
Inhibition of prostaglandin synthesis during polystyrene microsphere-induced pulmonary embolism in the rat.
|
Am J Physiol Lung Cell Mol Physiol
|
2003
|
0.93
|
|
57
|
Characteristics and outcomes of patients with vasoplegic versus tissue dysoxic septic shock.
|
Shock
|
2013
|
0.91
|
|
58
|
Potential impact of adjusting the threshold of the quantitative D-dimer based on pretest probability of acute pulmonary embolism.
|
Acad Emerg Med
|
2009
|
0.91
|
|
59
|
Interobserver agreement for the diagnosis of venous thromboembolism on computed tomography chest angiography and indirect venography of the lower extremities in emergency department patients.
|
Acad Emerg Med
|
2006
|
0.91
|
|
60
|
Emergency department resuscitative procedures: animal laboratory training improves procedural competency and speed.
|
Acad Emerg Med
|
2002
|
0.89
|
|
61
|
Plasma levels of mitochondrial DNA in patients presenting to the emergency department with sepsis.
|
Shock
|
2012
|
0.89
|
|
62
|
End tidal CO(2) is reduced during hypotension and cardiac arrest in a rat model of massive pulmonary embolism.
|
Resuscitation
|
2002
|
0.87
|
|
63
|
Development and comparison of a minimally-invasive model of autologous clot pulmonary embolism in Sprague-Dawley and Copenhagen rats.
|
Thromb J
|
2010
|
0.86
|
|
64
|
Therapy and outcomes in massive pulmonary embolism from the Emergency Medicine Pulmonary Embolism in the Real World Registry.
|
Am J Emerg Med
|
2012
|
0.86
|
|
65
|
Frequency of thrombophilia-related genetic variations in patients with idiopathic pulmonary embolism in an urban emergency department.
|
Clin Chem
|
2006
|
0.85
|
|
66
|
Proteomics of microparticles after experimental pulmonary embolism.
|
Thromb Res
|
2011
|
0.85
|
|
67
|
Multimarker panel to rule out acute coronary syndromes in low-risk patients.
|
Acad Emerg Med
|
2006
|
0.85
|
|
68
|
Estimating the pretest probability threshold to justify empiric administration of heparin prior to pulmonary vascular imaging for pulmonary embolism.
|
Thromb Res
|
2005
|
0.84
|
|
69
|
Effect of glucose-insulin-potassium infusion on mortality in critical care settings: a systematic review and meta-analysis.
|
J Clin Pharmacol
|
2009
|
0.84
|
|
70
|
Inhibition of CINC-1 decreases right ventricular damage caused by experimental pulmonary embolism in rats.
|
J Immunol
|
2007
|
0.84
|
|
71
|
Right ventricular heart failure from pulmonary embolism: key distinctions from chronic pulmonary hypertension.
|
J Card Fail
|
2010
|
0.84
|
|
72
|
12-lead ECG findings of pulmonary hypertension occur more frequently in emergency department patients with pulmonary embolism than in patients without pulmonary embolism.
|
Ann Emerg Med
|
2009
|
0.83
|
|
73
|
Transcriptional profile of right ventricular tissue during acute pulmonary embolism in rats.
|
Physiol Genomics
|
2008
|
0.83
|
|
74
|
Arginase depletes plasma l-arginine and decreases pulmonary vascular reserve during experimental pulmonary embolism.
|
Pulm Pharmacol Ther
|
2011
|
0.82
|
|
75
|
Effectiveness of the Chest Pain Choice decision aid in emergency department patients with low-risk chest pain: study protocol for a multicenter randomized trial.
|
Trials
|
2014
|
0.82
|
|
76
|
Up-regulation of arginase II contributes to pulmonary vascular endothelial cell dysfunction during experimental pulmonary embolism.
|
Pulm Pharmacol Ther
|
2011
|
0.81
|
|
77
|
Cardiac UCP2 expression and myocardial oxidative metabolism during acute septic shock in the rat.
|
Shock
|
2003
|
0.80
|
|
78
|
Prospective use of a clinical decision rule to identify pulmonary embolism as likely cause of outpatient cardiac arrest.
|
Resuscitation
|
2005
|
0.80
|
|
79
|
Transcriptional changes in right ventricular tissues are enriched in the outflow tract compared with the apex during chronic pulmonary embolism in rats.
|
Physiol Genomics
|
2009
|
0.80
|
|
80
|
Evaluation of capnography using a genetic algorithm to predict PaCO2.
|
Chest
|
2005
|
0.79
|
|
81
|
Contribution of fibrinolysis to the physical component summary of the SF-36 after acute submassive pulmonary embolism.
|
J Thromb Thrombolysis
|
2015
|
0.79
|
|
82
|
Lack of association between prehospital response times and patient outcomes.
|
Prehosp Emerg Care
|
2009
|
0.79
|
|
83
|
Venous thromboembolism: EINSTEIN transforms anticoagulant therapy in acute PE.
|
Nat Rev Cardiol
|
2012
|
0.79
|
|
84
|
Prognostic value of incremental lactate elevations in emergency department patients with suspected infection.
|
Acad Emerg Med
|
2012
|
0.79
|
|
85
|
Fatal pulmonary embolism immediately after transatlantic air travel to the United States: less than one in a million.
|
Thromb Haemost
|
2002
|
0.78
|
|
86
|
Direct comparison of the diagnostic accuracy of fifty protein biological markers of pulmonary embolism for use in the emergency department.
|
Acad Emerg Med
|
2008
|
0.78
|
|
87
|
The art and science of probabilistic decision-making in emergency medicine.
|
Acad Emerg Med
|
2010
|
0.78
|
|
88
|
Dichloroacetate increases skeletal muscle pyruvate dehydrogenase activity during acute limb ischemia.
|
Vasc Endovascular Surg
|
2003
|
0.78
|
|
89
|
Association of body mass index with increased cost of care and length of stay for emergency department patients with chest pain and dyspnea.
|
Circ Cardiovasc Qual Outcomes
|
2014
|
0.78
|
|
90
|
Contrast-induced nephropathy: doubts and certainties.
|
Acad Emerg Med
|
2012
|
0.78
|
|
91
|
Proinflammatory events in right ventricular damage during pulmonary embolism: effects of treatment with ketorolac in rats.
|
J Cardiovasc Pharmacol
|
2009
|
0.77
|
|
92
|
The effects of dichloroacetate in a rabbit model of acute hind-limb ischemia and reperfusion.
|
J Am Coll Surg
|
2003
|
0.77
|
|
93
|
The beneficial effects of dichloroacetate in acute limb ischemia.
|
Mil Med
|
2007
|
0.76
|
|
94
|
Tandem measurement of D-dimer and myeloperoxidase or C-reactive protein to effectively screen for pulmonary embolism in the emergency department.
|
Acad Emerg Med
|
2008
|
0.76
|
|
95
|
A soluble guanylate cyclase stimulator, BAY 41-8543, preserves right ventricular function in experimental pulmonary embolism.
|
Pulm Pharmacol Ther
|
2012
|
0.76
|
|
96
|
Diagnosing pulmonary embolism in the emergency department: maybe we do matter, after all.
|
Emerg Med Australas
|
2009
|
0.75
|
|
97
|
Serial Procalcitonin Predicts Mortality in Severe Sepsis Patients: Results From the Multicenter Procalcitonin MOnitoring SEpsis (MOSES) Study.
|
Crit Care Med
|
2017
|
0.75
|
|
98
|
Risk stratification of community-acquired pneumonia: what does all of this mean?
|
Ann Emerg Med
|
2008
|
0.75
|
|
99
|
More on the PERC rule.
|
Ann Emerg Med
|
2012
|
0.75
|
|
100
|
A primer on the complicated subject of cost-effectiveness analyses for pulmonary embolism.
|
Ann Emerg Med
|
2010
|
0.75
|
|
101
|
Making the black box more useful.
|
Emerg Med J
|
2014
|
0.75
|
|
102
|
Pleural effusions in the critically ill: the evolving role of bedside ultrasound.
|
Crit Care Med
|
2005
|
0.75
|
|
103
|
Crash course in decision making.
|
Acad Emerg Med
|
2004
|
0.75
|
|
104
|
Save the beans.
|
Ann Emerg Med
|
2010
|
0.75
|
|
105
|
End expiratory oxygen concentrations to predict central venous oxygen saturation: an observational pilot study.
|
BMC Emerg Med
|
2006
|
0.75
|
|
106
|
Computed tomography in the emergency department setting--reply.
|
JAMA Intern Med
|
2013
|
0.75
|
|
107
|
Elevated brain natriuretic peptide in septic patients without heart failure.
|
Ann Emerg Med
|
2003
|
0.75
|
|
108
|
Frequency of thromboprophylaxis and incidence of in-hospital venous thromboembolism in a cohort of emergency department patients.
|
J Thromb Thrombolysis
|
2007
|
0.75
|
|
109
|
Research priorities for the influence of gender on diagnostic imaging choices in the emergency department setting.
|
Acad Emerg Med
|
2014
|
0.75
|
|
110
|
Comparison of acute and convalescent biomarkers of inflammation in patients with acute pulmonary embolism treated with systemic fibrinolysis vs. placebo.
|
Blood Coagul Fibrinolysis
|
2017
|
0.75
|
|
111
|
Indirect computed tomography venography: a report of vascular opacification.
|
Emerg Radiol
|
2010
|
0.75
|