Published in BMC Med Genomics on May 30, 2014
Glutamine treatment attenuates hyperglycemia-induced mitochondrial stress and apoptosis in umbilical vein endothelial cells. Clinics (Sao Paulo) (2015) 1.65
Hyperglycemia induces Toll-like receptor-2 and -4 expression and activity in human microvascular retinal endothelial cells: implications for diabetic retinopathy. J Diabetes Res (2014) 1.61
Insulin resistance provides the connection between hepatitis C virus and diabetes. Hepat Mon (2014) 0.82
Stimulation of β-adrenergic receptors plays a protective role via increased expression of RAF-1 and PDX-1 in hyperglycemic rat pancreatic islet (RIN-m5F) cells. Arch Med Sci (2016) 0.75
Gelam Honey Attenuates the Oxidative Stress-Induced Inflammatory Pathways in Pancreatic Hamster Cells. Evid Based Complement Alternat Med (2016) 0.75
Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care (2004) 75.82
Human DNA methylomes at base resolution show widespread epigenomic differences. Nature (2009) 34.27
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet (2003) 25.57
Biochemistry and molecular cell biology of diabetic complications. Nature (2001) 25.43
DNA methylation and human disease. Nat Rev Genet (2005) 12.00
Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem Biol Interact (2006) 10.64
The prevalence of diabetic retinopathy among adults in the United States. Arch Ophthalmol (2004) 6.53
Role of oxygen radicals in DNA damage and cancer incidence. Mol Cell Biochem (2004) 3.54
International Union of Pharmacology nomenclature of adrenoceptors. Pharmacol Rev (1994) 3.26
Epigenetics: a molecular link between environmental factors and type 2 diabetes. Diabetes (2009) 2.96
Epidemiology of diabetic retinopathy and macular oedema: a systematic review. Eye (Lond) (2004) 2.54
Appearance of brown adipocytes in white adipose tissue during CL 316,243-induced reversal of obesity and diabetes in Zucker fa/fa rats. Int J Obes Relat Metab Disord (1997) 2.40
Beta-adrenergic receptors: biochemical mechanisms of physiological regulation. Physiol Rev (1984) 2.38
Functional beta3-adrenoceptor in the human heart. J Clin Invest (1996) 2.32
Epigenetic modulation of the renal β-adrenergic-WNK4 pathway in salt-sensitive hypertension. Nat Med (2011) 2.18
Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion. Diabetologia (2008) 2.15
TNF-alpha mediated apoptosis plays an important role in the development of early diabetic retinopathy and long-term histopathological alterations. Mol Vis (2009) 2.08
From genome to epigenome. Hum Mol Genet (2005) 2.03
CpG methylation as a mechanism for the regulation of E2F activity. Proc Natl Acad Sci U S A (2000) 1.86
Diabetic retinopathy: mitochondrial dysfunction and retinal capillary cell death. Antioxid Redox Signal (2005) 1.86
Expression of apoptosis markers in the retinas of human subjects with diabetes. Invest Ophthalmol Vis Sci (2004) 1.73
DNA methylation presents distinct binding sites for human transcription factors. Elife (2013) 1.63
Structure of the gene for human beta 2-adrenergic receptor: expression and promoter characterization. Proc Natl Acad Sci U S A (1987) 1.62
Mitochondrial protein acylation and intermediary metabolism: regulation by sirtuins and implications for metabolic disease. J Biol Chem (2012) 1.58
Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle. Diabetologia (2008) 1.50
Epigenetic mechanisms in diabetic vascular complications. Cardiovasc Res (2011) 1.43
Beta 3-adrenergic receptors regulate retinal endothelial cell migration and proliferation. J Biol Chem (2003) 1.41
Role of beta-adrenergic receptors in inflammatory marker expression in Müller cells. Invest Ophthalmol Vis Sci (2007) 1.40
The dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding. Carcinogenesis (2006) 1.25
Involvement of endothelial cells in relaxation and contraction responses of the aorta to isoproterenol in naive and streptozotocin-induced diabetic rats. J Pharmacol Exp Ther (1989) 1.24
Overview: combating diabetic nephropathy. J Am Soc Nephrol (2003) 1.22
Impaired redox signaling and antioxidant gene expression in endothelial cells in diabetes: a role for mitochondria and the nuclear factor-E2-related factor 2-Kelch-like ECH-associated protein 1 defense pathway. Antioxid Redox Signal (2010) 1.19
Association of polymorphisms in the beta2-adrenergic receptor gene with obesity, hypertriglyceridaemia, and diabetes mellitus. Diabetologia (1999) 1.19
Oxygen-regulated erythropoietin gene expression is dependent on a CpG methylation-free hypoxia-inducible factor-1 DNA-binding site. Eur J Biochem (1998) 1.14
Systemic propranolol reduces b-wave amplitude in the ERG and increases IGF-1 receptor phosphorylation in rat retina. Invest Ophthalmol Vis Sci (2009) 1.08
Maintenance of beta-adrenergic receptor signaling can reduce Fas signaling in human retinal endothelial cells. Exp Eye Res (2009) 1.06
Aberrant DNA methylation in malignant melanoma. Melanoma Res (2010) 1.04
Microvascular complications of diabetes. Endocrinol Metab Clin North Am (2004) 1.03
DNA methylation and the association between genetic and epigenetic changes: relation to carcinogenesis. Mutat Res (1997) 1.02
Therapeutic potential of anti-oxidants and diabetic retinopathy. Expert Opin Investig Drugs (2001) 0.98
Epigenetics in hyperhomocysteinemic states. A special focus on uremia. Biochim Biophys Acta (2008) 0.97
Beta-adrenergic receptor stimulation modulates iNOS protein levels through p38 and ERK1/2 signaling in human retinal endothelial cells. Exp Eye Res (2008) 0.95
The epigenetic conductor: a genomic orchestrator in chronic kidney disease complications? J Nephrol (2009) 0.92
Endogenous expression of adenosine A1, A2 and A3 receptors in rat C6 glioma cells. Neurochem Res (2007) 0.90
Functional expression of beta2 adrenergic receptors responsible for protection against oxidative stress through promotion of glutathione synthesis after Nrf2 upregulation in undifferentiated mesenchymal C3H10T1/2 stem cells. J Cell Physiol (2009) 0.90
Deficiency of cardiac beta-adrenergic receptor in streptozocin-induced diabetic rats. Diabetes (1988) 0.87
Beta adrenergic binding sites in the human eye: an autoradiographic study. J Ocul Pharmacol (1990) 0.85
Lipids versus glucose in inflammation and the pathogenesis of macrovascular disease in diabetes. Curr Diab Rep (2009) 0.84
beta-adrenergic mechanisms in cardiac diseases: a perspective. Cell Signal (2000) 0.83
Similarities and differences in the coupling of human beta1- and beta2-adrenoceptors to Gs(alpha) splice variants. Biochem Pharmacol (2002) 0.83
Association of beta3-adrenergic receptor gene polymorphism with insulin resistance in Japanese-American men. Metabolism (1999) 0.81
[Association between beta3-adrenergic receptor and oxidative stress in chronic heart failure rats]. Zhonghua Xin Xue Guan Bing Za Zhi (2010) 0.79
The beta3-adrenergic receptor in the obesity and diabetes prone rhesus monkey is very similar to human and contains arginine at codon 64. Gene (1997) 0.77
Detection of quorum sensing signal molecules and identification of an autoinducer synthase gene among biofilm forming clinical isolates of Acinetobacter spp. PLoS One (2012) 1.03
Effect of gelam honey on the oxidative stress-induced signaling pathways in pancreatic hamster cells. Int J Endocrinol (2013) 0.83
Pregnancy-induced hypertension and preeclampsia: levels of angiogenic factors in malaysian women. J Clin Biochem Nutr (2010) 0.83
Development of conventional and real-time multiplex PCR assays for the detection of nosocomial pathogens. Braz J Microbiol (2011) 0.83
The antioxidant effect of the Malaysian Gelam honey on pancreatic hamster cells cultured under hyperglycemic conditions. Clin Exp Med (2013) 0.83
The oxidative stress of hyperglycemia and the inflammatory process in endothelial cells. J Med Invest (2009) 0.82
F(2)-isoprostanes as novel biomarkers for type 2 diabetes: a review. J Clin Biochem Nutr (2009) 0.79
Thrombophilic mutations in pre-eclampsia and pregnancy-induced hypertension. J Obstet Gynaecol Res (2008) 0.75
Kinetic studies of bioactive products nitric oxide and 8-iso-PGF(2alpha) in Burkholderia pseudomallei infected human macrophages, and their role in the intracellular survival of these organisms. FEMS Immunol Med Microbiol (2005) 0.75