Published in BMC Genomics on May 22, 2014
Origin-Dependent Inverted-Repeat Amplification: Tests of a Model for Inverted DNA Amplification. PLoS Genet (2015) 0.78
A pilot study on the prevalence of DNA palindromes in breast cancer genomes. BMC Med Genomics (2016) 0.75
BLAT--the BLAST-like alignment tool. Genome Res (2002) 126.78
A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics (2003) 82.89
A census of human cancer genes. Nat Rev Cancer (2004) 36.20
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell (2006) 27.36
Recent segmental duplications in the human genome. Science (2002) 21.30
The Stability of Broken Ends of Chromosomes in Zea Mays. Genetics (1941) 16.95
A human cell line from a pleural effusion derived from a breast carcinoma. J Natl Cancer Inst (1973) 10.64
Analysis of repeating DNA sequences by reassociation. Methods Enzymol (1974) 10.63
The mutation spectrum revealed by paired genome sequences from a lung cancer patient. Nature (2010) 10.04
Mechanisms of change in gene copy number. Nat Rev Genet (2009) 9.01
Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction. BMC Bioinformatics (2012) 8.61
End-sequence profiling: sequence-based analysis of aberrant genomes. Proc Natl Acad Sci U S A (2003) 7.70
A microhomology-mediated break-induced replication model for the origin of human copy number variation. PLoS Genet (2009) 6.39
Whole genome DNA copy number changes identified by high density oligonucleotide arrays. Hum Genomics (2004) 5.65
A census of amplified and overexpressed human cancer genes. Nat Rev Cancer (2010) 4.47
Novel patterns of genome rearrangement and their association with survival in breast cancer. Genome Res (2006) 4.25
A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome. Genome Res (2008) 4.06
Long DNA palindromes, cruciform structures, genetic instability and secondary structure repair. Bioessays (1994) 2.91
Mechanisms for recurrent and complex human genomic rearrangements. Curr Opin Genet Dev (2012) 2.67
High-resolution genomic profiles of breast cancer cell lines assessed by tiling BAC array comparative genomic hybridization. Genes Chromosomes Cancer (2007) 2.34
Chromosomal alterations in 15 breast cancer cell lines by comparative genomic hybridization and spectral karyotyping. Genes Chromosomes Cancer (2000) 2.24
Decoding the fine-scale structure of a breast cancer genome and transcriptome. Genome Res (2006) 2.09
Cloning of BCAS3 (17q23) and BCAS4 (20q13) genes that undergo amplification, overexpression, and fusion in breast cancer. Genes Chromosomes Cancer (2002) 2.04
Precise determination of mitochondrial DNA copy number in human skeletal and cardiac muscle by a PCR-based assay: lack of change of copy number with age. Nucleic Acids Res (2003) 2.02
Comprehensive copy number profiles of breast cancer cell model genomes. Breast Cancer Res (2006) 2.02
Widespread and nonrandom distribution of DNA palindromes in cancer cells provides a structural platform for subsequent gene amplification. Nat Genet (2005) 1.99
Inverted genomic segments and complex triplication rearrangements are mediated by inverted repeats in the human genome. Nat Genet (2011) 1.93
Comprehensive long-span paired-end-tag mapping reveals characteristic patterns of structural variations in epithelial cancer genomes. Genome Res (2011) 1.67
Palindromic gene amplification--an evolutionarily conserved role for DNA inverted repeats in the genome. Nat Rev Cancer (2009) 1.62
A sequence-based survey of the complex structural organization of tumor genomes. Genome Biol (2008) 1.45
A mechanism of palindromic gene amplification in Saccharomyces cerevisiae. Genes Dev (2005) 1.45
Palindrome-mediated chromosomal translocations in humans. DNA Repair (Amst) (2006) 1.43
Oncogenes and tumor suppressor genes in breast cancer: potential diagnostic and therapeutic applications. Oncologist (2004) 1.37
Intrastrand annealing leads to the formation of a large DNA palindrome and determines the boundaries of genomic amplification in human cancer. Mol Cell Biol (2007) 1.36
Hairpin- and cruciform-mediated chromosome breakage: causes and consequences in eukaryotic cells. Front Biosci (2007) 1.31
Short inverted repeats initiate gene amplification through the formation of a large DNA palindrome in mammalian cells. Proc Natl Acad Sci U S A (2002) 1.30
Chromosomal instability mediated by non-B DNA: cruciform conformation and not DNA sequence is responsible for recurrent translocation in humans. Genome Res (2008) 1.27
Aberrations of chromosome 8 in 16 breast cancer cell lines by comparative genomic hybridization, fluorescence in situ hybridization, and spectral karyotyping. Cancer Genet Cytogenet (2001) 1.11
Palindromic AT-rich repeat in the NF1 gene is hypervariable in humans and evolutionarily conserved in primates. Hum Mutat (2005) 1.09
Palindromes and genomic stress fractures: bracing and repairing the damage. DNA Repair (Amst) (2006) 1.05
Linkage disequilibrium between two high-frequency deletion polymorphisms: implications for association studies involving the glutathione-S transferase (GST) genes. PLoS Genet (2009) 1.01
Large DNA palindromes as a common form of structural chromosome aberrations in human cancers. Hum Cell (2006) 0.96
Genome-wide detection and analysis of recent segmental duplications within mammalian organisms. Cold Spring Harb Symp Quant Biol (2003) 0.95
Long span DNA paired-end-tag (DNA-PET) sequencing strategy for the interrogation of genomic structural mutations and fusion-point-guided reconstruction of amplicons. PLoS One (2012) 0.89
Assessment of palindromes as platforms for DNA amplification in breast cancer. Genome Res (2011) 0.88
New approaches to the analysis of palindromic sequences from the human genome: evolution and polymorphism of an intronic site at the NF1 locus. Nucleic Acids Res (2005) 0.85
Genome-wide analysis of palindrome formation. Nat Genet (2010) 0.79
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell (2013) 24.00
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. Cancer Cell (2011) 11.44
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature (2011) 6.73
Full-length messenger RNA sequences greatly improve genome annotation. Genome Biol (2002) 4.90
Initial sequence and comparative analysis of the cat genome. Genome Res (2007) 4.67
Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system. Cell Res (2013) 3.50
Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia. Blood (2006) 3.48
Functional genomics of genes with small open reading frames (sORFs) in S. cerevisiae. Genome Res (2006) 2.81
Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors. Genes Dev (2012) 2.70
Shear stress induces endothelial differentiation from a murine embryonic mesenchymal progenitor cell line. Arterioscler Thromb Vasc Biol (2005) 2.51
Randomized open-label phase II study of decitabine in patients with low- or intermediate-risk myelodysplastic syndromes. J Clin Oncol (2013) 2.42
High-efficiency InGaN-based LEDs grown on patterned sapphire substrates. Opt Express (2011) 2.14
Phase 1 study of the oral isotype specific histone deacetylase inhibitor MGCD0103 in leukemia. Blood (2008) 2.04
Essential role of microRNA-155 in regulating endothelium-dependent vasorelaxation by targeting endothelial nitric oxide synthase. Hypertension (2012) 1.92
Adaptive diversification of bitter taste receptor genes in Mammalian evolution. Mol Biol Evol (2003) 1.82
Mouse endogenous retroviruses can trigger premature transcriptional termination at a distance. Genome Res (2012) 1.81
The common inhalational anesthetic isoflurane induces apoptosis via activation of inositol 1,4,5-trisphosphate receptors. Anesthesiology (2008) 1.79
Ego3 functions as a homodimer to mediate the interaction between Gtr1-Gtr2 and Ego1 in the ego complex to activate TORC1. Structure (2012) 1.77
The identification of microRNAs in a genomically unstable region of human chromosome 8q24. Mol Cancer Res (2008) 1.71
DBParser: web-based software for shotgun proteomic data analyses. J Proteome Res (2004) 1.69
Extensive variation between inbred mouse strains due to endogenous L1 retrotransposition. Genome Res (2008) 1.69
Isoflurane preconditioning inhibited isoflurane-induced neurotoxicity. Neurosci Lett (2007) 1.53
[Effects of different statin regimens on lipid profile and serum metalloproteinases in patients with coronary heart disease]. Zhonghua Xin Xue Guan Bing Za Zhi (2009) 1.50
Fractional anisotropy and tumor cell density of the tumor core show positive correlation in diffusion tensor magnetic resonance imaging of malignant brain tumors. Neuroimage (2008) 1.46
An orthophosphate semiconductor with photooxidation properties under visible-light irradiation. Nat Mater (2010) 1.46
Analysis of 454 sequencing error rate, error sources, and artifact recombination for detection of Low-frequency drug resistance mutations in HIV-1 DNA. Retrovirology (2013) 1.45
Adipokine resistin promotes in vitro angiogenesis of human endothelial cells. Cardiovasc Res (2006) 1.45
The role of a novel p97/valosin-containing protein-interacting motif of gp78 in endoplasmic reticulum-associated degradation. J Biol Chem (2006) 1.43
HIV prevalence and correlates of unprotected anal intercourse among men who have sex with men, Jinan, China. AIDS Behav (2008) 1.41
Phase I study of epigenetic modulation with 5-azacytidine and valproic acid in patients with advanced cancers. Clin Cancer Res (2008) 1.41
Left atrial dyssynchrony time measured by tissue Doppler imaging to predict atrial fibrillation recurrences after pulmonary vein isolation. Anatol J Cardiol (2014) 1.40
Zscan4 promotes genomic stability during reprogramming and dramatically improves the quality of iPS cells as demonstrated by tetraploid complementation. Cell Res (2012) 1.39
Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact. Epigenetics (2010) 1.37
Downregulation of JUNB mRNA expression in advanced phase chronic myelogenous leukemia. Leuk Res (2009) 1.37
Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors. Nucleic Acids Res (2014) 1.34
Growth signaling promotes chronological aging in budding yeast by inducing superoxide anions that inhibit quiescence. Aging (Albany NY) (2010) 1.33
Rising HIV prevalence among married and unmarried among men who have sex with men: Jinan, China. AIDS Behav (2009) 1.32
The association of serotonin transporter genetic polymorphisms and irritable bowel syndrome and its influence on tegaserod treatment in Chinese patients. Dig Dis Sci (2007) 1.32
Hairpin- and cruciform-mediated chromosome breakage: causes and consequences in eukaryotic cells. Front Biosci (2007) 1.31
Diversity of rotavirus strains among children with acute diarrhea in China: 1998-2000 surveillance study. J Clin Microbiol (2002) 1.29
Phosphorylated α-synuclein in Parkinson's disease. Sci Transl Med (2012) 1.29
Genome-wide analysis reveals gene expression and metabolic network dynamics during embryo development in Arabidopsis. Plant Physiol (2011) 1.29
The substantial hospitalization burden of influenza in central China: surveillance for severe, acute respiratory infection, and influenza viruses, 2010-2012. Influenza Other Respir Viruses (2013) 1.28
Anti-inflammatory and immunosuppressive compounds from Tripterygium wilfordii. Phytochemistry (2007) 1.26
DNA methylation of developmental genes in pediatric medulloblastomas identified by denaturation analysis of methylation differences. Proc Natl Acad Sci U S A (2009) 1.26
Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-like protein kinase genes in Arabidopsis thaliana. BMC Genomics (2010) 1.23
Which Chinese men who have sex with men miss out on HIV testing? Sex Transm Infect (2011) 1.22
Pancreatic carcinoma cells express neuropilins and vascular endothelial growth factor, but not vascular endothelial growth factor receptors. Cancer (2004) 1.22
Antileukemia activity of the combination of an anthracycline with a histone deacetylase inhibitor. Blood (2006) 1.22
Bioactive novel polyphenols from the fruit of Manilkara zapota (Sapodilla). J Nat Prod (2003) 1.22
Impact of chromatin structure on sequence variability in the human genome. Nat Struct Mol Biol (2011) 1.21
Setbp1 promotes the self-renewal of murine myeloid progenitors via activation of Hoxa9 and Hoxa10. Blood (2012) 1.21
Molecular basis of spectral tuning in the red- and green-sensitive (M/LWS) pigments in vertebrates. Genetics (2008) 1.21
Public perceptions of private health care in socialist China. Health Aff (Millwood) (2004) 1.20
Gene regulation and epigenetic remodeling in murine embryonic stem cells by c-Myc. PLoS One (2009) 1.20
Downregulation of TMEM16A calcium-activated chloride channel contributes to cerebrovascular remodeling during hypertension by promoting basilar smooth muscle cell proliferation. Circulation (2012) 1.20
Modulation of macrophage activation and programming in immunity. J Cell Physiol (2013) 1.17
MicroRNAs and genomic instability. Semin Cancer Biol (2006) 1.14
Aberrant DNA methylation and epigenetic inactivation of Eph receptor tyrosine kinases and ephrin ligands in acute lymphoblastic leukemia. Blood (2010) 1.14
Roles of cyclophilins in cancers and other organ systems. World J Surg (2005) 1.14
Stem cells from human-exfoliated deciduous teeth can differentiate into dopaminergic neuron-like cells. Stem Cells Dev (2010) 1.13
Evolutionary dynamics of the interferon-induced transmembrane gene family in vertebrates. PLoS One (2012) 1.13
Intensity-modulated microbend fiber optic sensor for respiratory monitoring and gating during MRI. IEEE Trans Biomed Eng (2013) 1.13
Structure of the Fab fragment of therapeutic antibody Ofatumumab provides insights into the recognition mechanism with CD20. Mol Immunol (2009) 1.12
Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound β-phenylethyl isothiocyanate. Blood (2010) 1.12
Bioassay-guided isolation of aldose reductase inhibitors from Artemisia dracunculus. Phytochemistry (2006) 1.12
Analysis of polyphenolic antioxidants from the fruits of three pouteria species by selected ion monitoring liquid chromatography-mass spectrometry. J Agric Food Chem (2004) 1.11
Ectodermal Wnt/β-catenin signaling shapes the mouse face. Dev Biol (2010) 1.10
Phase II trial of vorinostat with idarubicin and cytarabine for patients with newly diagnosed acute myelogenous leukemia or myelodysplastic syndrome. J Clin Oncol (2012) 1.10
Oncogenic functions of the transcription factor Nrf2. Free Radic Biol Med (2013) 1.10
An integrated microfluidic array system for evaluating toxicity and teratogenicity of drugs on embryonic zebrafish developmental dynamics. Biomicrofluidics (2011) 1.10
Curcumin attenuates EGF-induced AQP3 up-regulation and cell migration in human ovarian cancer cells. Cancer Chemother Pharmacol (2008) 1.09
The combination of a histone deacetylase inhibitor with the Bcl-2 homology domain-3 mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagy. Clin Cancer Res (2010) 1.08
Viral infection and focal cortical dysplasia. Ann Neurol (2014) 1.08
Quantitative analysis of antiradical phenolic constituents from fourteen edible Myrtaceae fruits. Food Chem (2008) 1.08
Adaptive diversification of vomeronasal receptor 1 genes in rodents. J Mol Evol (2005) 1.07
Bioactive depsides and anthocyanins from jaboticaba (Myrciaria cauliflora). J Nat Prod (2006) 1.07
alpha-Synuclein is differentially expressed in mitochondria from different rat brain regions and dose-dependently down-regulates complex I activity. Neurosci Lett (2009) 1.07
Non-B DB: a database of predicted non-B DNA-forming motifs in mammalian genomes. Nucleic Acids Res (2010) 1.07
A metal-based inhibitor of tumor necrosis factor-α. Angew Chem Int Ed Engl (2012) 1.06
Effects of 5 HIV protease inhibitors on vasomotor function and superoxide anion production in porcine coronary arteries. J Acquir Immune Defic Syndr (2005) 1.06
Influence of polygenetic polymorphisms on the susceptibility to non-alcoholic fatty liver disease of Chinese people. J Gastroenterol Hepatol (2010) 1.05
Semi-quantitative analysis of alpha-synuclein in subcellular pools of rat brain neurons: an immunogold electron microscopic study using a C-terminal specific monoclonal antibody. Brain Res (2008) 1.04
Epigenetics of acute lymphocytic leukemia. Semin Hematol (2009) 1.04
Gene network reconstruction reveals cell cycle and antiviral genes as major drivers of cervical cancer. Nat Commun (2013) 1.03
Growth inhibition of colon cancer cells by polyisoprenylated benzophenones is associated with induction of the endoplasmic reticulum response. Int J Cancer (2008) 1.03
Genome-wide association study of meat quality traits in a White Duroc×Erhualian F2 intercross and Chinese Sutai pigs. PLoS One (2013) 1.03
USF1 and hSET1A mediated epigenetic modifications regulate lineage differentiation and HoxB4 transcription. PLoS Genet (2013) 1.03
Bioactive benzophenones from Garcinia xanthochymus fruits. J Nat Prod (2005) 1.03
China's evolving health care market: how doctors feel and what they think. Health Policy (2004) 1.02
The activation of HMGB1 as a progression factor on inflammation response in normal human bronchial epithelial cells through RAGE/JNK/NF-κB pathway. Mol Cell Biochem (2013) 1.01
Linkage disequilibrium between two high-frequency deletion polymorphisms: implications for association studies involving the glutathione-S transferase (GST) genes. PLoS Genet (2009) 1.01
Transcription signatures encoded by ultraconserved genomic regions in human prostate cancer. Mol Cancer (2013) 1.01
Controlling assembly of paired gold clusters within apoferritin nanoreactor for in vivo kidney targeting and biomedical imaging. J Am Chem Soc (2011) 1.00
Association of bone morphogenetic protein-2 gene polymorphisms with susceptibility to ossification of the posterior longitudinal ligament of the spine and its severity in Chinese patients. Eur Spine J (2008) 1.00
[Transported fluxes of the riverine carbon and seasonal variation in Pearl River basin]. Huan Jing Ke Xue (2013) 1.00
Involvement of ERK1/2 signaling pathway in DJ-1-induced neuroprotection against oxidative stress. Biochem Biophys Res Commun (2009) 1.00
YGR198w (YPP1) targets A30P alpha-synuclein to the vacuole for degradation. J Cell Biol (2007) 1.00