Published in Clin Exp Med on June 13, 2014
Sirtuin 1: A Target for Kidney Diseases. Mol Med (2015) 0.77
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell (1997) 21.42
Cellular survival: a play in three Akts. Genes Dev (1999) 17.05
PI3K: downstream AKTion blocks apoptosis. Cell (1997) 7.73
TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science (2003) 5.25
TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death. EMBO J (2005) 4.51
Emerging roles of pseudokinases. Trends Cell Biol (2006) 4.48
Proteinuria and hyperglycemia induce endoplasmic reticulum stress. J Am Soc Nephrol (2008) 2.41
Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils. J Biol Chem (2004) 2.30
The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change. Oncogene (2001) 1.70
PKC-delta promotes renal tubular cell apoptosis associated with proteinuria. J Am Soc Nephrol (2010) 1.67
Tribbles: a family of kinase-like proteins with potent signalling regulatory function. Cell Signal (2006) 1.61
Akt is more than just a Bad kinase. Nature (1999) 1.60
SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia. Oncogene (2003) 1.52
Albumin induces endoplasmic reticulum stress and apoptosis in renal proximal tubular cells. Kidney Int (2006) 1.46
Akt is a downstream target of NF-kappa B. J Biol Chem (2002) 1.43
Chronic ethanol intake impairs insulin signaling in rats by disrupting Akt association with the cell membrane. Role of TRB3 in inhibition of Akt/protein kinase B activation. J Biol Chem (2006) 1.32
TRB3 protects cells against the growth inhibitory and cytotoxic effect of ATF4. Exp Cell Res (2007) 1.28
TRB3 is a PI 3-kinase dependent indicator for nutrient starvation. Cell Signal (2005) 1.20
Characterization of human NIPK (TRB3, SKIP3) gene activation in stressful conditions. Biochem Biophys Res Commun (2005) 1.17
PKB and megalin determine the survival or death of renal proximal tubule cells. Proc Natl Acad Sci U S A (2006) 1.16
Mitochondria are the major targets in albumin-induced apoptosis in proximal tubule cells. J Am Soc Nephrol (2007) 1.13
Activation of PI3K/Akt/IKK-alpha/NF-kappaB signaling pathway is required for the apoptosis-evasion in human salivary adenoid cystic carcinoma: its inhibition by quercetin. Apoptosis (2010) 1.12
Tribbles: novel regulators of cell function; evolutionary aspects. Cell Mol Life Sci (2006) 1.11
Inhibition of NF-kappaB-dependent Bcl-xL expression by clusterin promotes albumin-induced tubular cell apoptosis. Kidney Int (2007) 1.11
Genotoxic and endoplasmic reticulum stresses differentially regulate TRB3 expression. Cancer Biol Ther (2005) 1.06
Characterization of a caspase-3-substrate kinome using an N- and C-terminally tagged protein kinase library produced by a cell-free system. Cell Death Dis (2010) 1.00
Increased expression of the Akt/PKB inhibitor TRB3 in osteoarthritic chondrocytes inhibits insulin-like growth factor 1-mediated cell survival and proteoglycan synthesis. Arthritis Rheum (2009) 0.99
TRB3, upregulated by ox-LDL, mediates human monocyte-derived macrophage apoptosis. FEBS J (2009) 0.99
Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cells. J Biol Chem (2010) 0.96
Novel combination of celecoxib and proteasome inhibitor MG132 provides synergistic antiproliferative and proapoptotic effects in human liver tumor cells. Cell Cycle (2010) 0.95
The role of protein traffic in the progression of renal diseases. Annu Rev Med (2000) 0.89
Stress-inducible caspase substrate TRB3 promotes nuclear translocation of procaspase-3. PLoS One (2012) 0.83
Knockdown of TRB3 induces apoptosis in human lung adenocarcinoma cells through regulation of Notch 1 expression. Mol Med Rep (2013) 0.82
Molecular interactions between albumin and proximal tubular cells. Exp Nephrol (1999) 0.79
Proteinuria and progression of glomerular diseases. Pediatr Nephrol (2012) 0.78
TRB3 mediates homocysteine-induced inhibition of endothelial cell proliferation. J Cell Physiol (2011) 0.77
The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements. Nat Biotechnol (2006) 30.90
The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models. Nat Biotechnol (2010) 7.08
Depressive symptoms and health-related quality of life: the Heart and Soul Study. JAMA (2003) 7.01
Effects of cigarette smoke on the human airway epithelial cell transcriptome. Proc Natl Acad Sci U S A (2004) 4.89
Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer. Nat Med (2007) 4.63
Automatic clustering of orthologs and inparalogs shared by multiple proteomes. Bioinformatics (2006) 3.98
Plasma soluble urokinase receptor levels are increased but do not distinguish primary from secondary focal segmental glomerulosclerosis. Kidney Int (2013) 3.97
Anatase TiO2 single crystals with a large percentage of reactive facets. Nature (2008) 3.66
Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH. Nature (2013) 3.22
ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance. Nat Immunol (2004) 3.19
Predictive factors for glaucomatous visual field progression in the Advanced Glaucoma Intervention Study. Ophthalmology (2004) 3.14
Transcriptome profiling, molecular biological, and physiological studies reveal a major role for ethylene in cotton fiber cell elongation. Plant Cell (2006) 2.87
OpenIGTLink: an open network protocol for image-guided therapy environment. Int J Med Robot (2009) 2.80
Distinctive microRNA profiles relating to patient survival in esophageal squamous cell carcinoma. Cancer Res (2008) 2.75
Caribbean corals in crisis: record thermal stress, bleaching, and mortality in 2005. PLoS One (2010) 2.69
Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis. Am J Hum Genet (2008) 2.65
Prednisone in Uric Acid lowering in Symptomatic Heart Failure Patients With Hyperuricemia (PUSH-PATH) study. Can J Cardiol (2013) 2.60
Analysis of wave behavior in lossy dielectric samples at high field. Magn Reson Med (2002) 2.59
Regulation of RNA-polymerase-II-dependent transcription by N-WASP and its nuclear-binding partners. Nat Cell Biol (2006) 2.52
Exome sequencing identifies ZNF644 mutations in high myopia. PLoS Genet (2011) 2.52
Comprehensive analysis of oncogenic effects of PIK3CA mutations in human mammary epithelial cells. Breast Cancer Res Treat (2007) 2.49
Gene expression in lung adenocarcinomas of smokers and nonsmokers. Am J Respir Cell Mol Biol (2003) 2.45
MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium. Proc Natl Acad Sci U S A (2009) 2.37
Diagnostic and prognostic implications of microRNAs in human hepatocellular carcinoma. Int J Cancer (2008) 2.35
Gene expression profiling of human lung tissue from smokers with severe emphysema. Am J Respir Cell Mol Biol (2004) 2.33
TRIP8b splice variants form a family of auxiliary subunits that regulate gating and trafficking of HCN channels in the brain. Neuron (2009) 2.30
TLR4 links podocytes with the innate immune system to mediate glomerular injury. J Am Soc Nephrol (2008) 2.23
Reversible and permanent effects of tobacco smoke exposure on airway epithelial gene expression. Genome Biol (2007) 2.20
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease. Nat Genet (2012) 2.17
Activation of AMPK attenuates neutrophil proinflammatory activity and decreases the severity of acute lung injury. Am J Physiol Lung Cell Mol Physiol (2008) 2.15
The structure of ferrihydrite, a nanocrystalline material. Science (2007) 2.11
CD4+CD25+ regulatory T cells suppress differentiation and functions of Th1 and Th2 cells, Leishmania major infection, and colitis in mice. J Immunol (2003) 2.11
Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium. BMC Genomics (2008) 2.11
Krüppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion. Cancer Res (2007) 2.02
Localization of all seven messenger RNAs for the actin-polymerization nucleator Arp2/3 complex in the protrusions of fibroblasts. J Cell Sci (2005) 1.95
Instrumental variable methods for causal inference. Stat Med (2014) 1.90
Airway PI3K pathway activation is an early and reversible event in lung cancer development. Sci Transl Med (2010) 1.84
A 5-microRNA signature for lung squamous cell carcinoma diagnosis and hsa-miR-31 for prognosis. Clin Cancer Res (2011) 1.82
Re-evaluation of the histopathologic classification of ANCA-associated glomerulonephritis: a study of 121 patients in a single center. Nephrol Dial Transplant (2011) 1.82
Antiinflammatory effects of hydrogen peroxide in neutrophil activation and acute lung injury. Am J Respir Crit Care Med (2009) 1.77
Asthma numeracy skill and health literacy. J Asthma (2006) 1.77
Proteomic fingerprints for potential application to early diagnosis of severe acute respiratory syndrome. Clin Chem (2004) 1.76
Acid rain in China. Environ Sci Technol (2006) 1.75
miR-146a inhibits cell growth, cell migration and induces apoptosis in non-small cell lung cancer cells. PLoS One (2013) 1.75
HMGB1 inhibits macrophage activity in efferocytosis through binding to the alphavbeta3-integrin. Am J Physiol Cell Physiol (2010) 1.75
A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment. Am J Respir Crit Care Med (2013) 1.73
Forkhead transcription factor foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis. Cancer Res (2011) 1.71
Identification of a microRNA signature in renal fibrosis: role of miR-21. Am J Physiol Renal Physiol (2011) 1.70
Mitochondrial iron detoxification is a primary function of frataxin that limits oxidative damage and preserves cell longevity. Hum Mol Genet (2005) 1.69
Surface-engineered magnetic nanoparticle platforms for cancer imaging and therapy. Acc Chem Res (2011) 1.69
Inference for the effect of treatment on survival probability in randomized trials with noncompliance and administrative censoring. Biometrics (2011) 1.68
Region-specific alternative splicing in the nervous system: implications for regulation by the RNA-binding protein NAPOR. RNA (2002) 1.65
Participation of the urokinase receptor in neutrophil efferocytosis. Blood (2009) 1.62
Potential role of high-mobility group box 1 in cystic fibrosis airway disease. Am J Respir Crit Care Med (2008) 1.62
Mitochondrial respiratory complex I regulates neutrophil activation and severity of lung injury. Am J Respir Crit Care Med (2008) 1.61
Ligand-dependent scope and divergent mechanistic behavior in nickel-catalyzed reductive couplings of aldehydes and alkynes. J Am Chem Soc (2004) 1.59
A highly homozygous and parthenogenetic human embryonic stem cell line derived from a one-pronuclear oocyte following in vitro fertilization procedure. Cell Res (2007) 1.58
Segmental instability in cervical spondylotic myelopathy with severe disc degeneration. Spine (Phila Pa 1976) (2006) 1.56
The renal histopathological spectrum of patients with nephrotic syndrome: an analysis of 1523 patients in a single Chinese centre. Nephrol Dial Transplant (2011) 1.54
Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment. J Alzheimers Dis (2010) 1.54
Reduced Th17 response in patients with tuberculosis correlates with IL-6R expression on CD4+ T Cells. Am J Respir Crit Care Med (2009) 1.54
Targeted disruption of MCPIP1/Zc3h12a results in fatal inflammatory disease. Immunol Cell Biol (2013) 1.53
Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases. Nature (2016) 1.52
Functional magnetic resonance imaging activation of the brain in children: real acupoint versus sham acupoint. J Child Neurol (2010) 1.51
Pathologic predictors of renal outcome and therapeutic efficacy in IgA nephropathy: validation of the oxford classification. Clin J Am Soc Nephrol (2011) 1.51
Surveillance of macrolide-resistant Mycoplasma pneumoniae in Beijing, China, from 2008 to 2012. Antimicrob Agents Chemother (2012) 1.51
Effect of acupuncture on the brain in children with spastic cerebral palsy using functional neuroimaging (FMRI). J Child Neurol (2008) 1.51
Tuning of the outer hair cell motor by membrane cholesterol. J Biol Chem (2007) 1.46
Efficient synthesis and properties of isomeric photochromic diarylethenes having a pyrrole unit. Org Lett (2007) 1.46
Plasmon resonance enhanced multicolour photodetection by graphene. Nat Commun (2011) 1.45
Isolation and characterization of fourteen novel putative and nine known target genes of the p53 family. Cancer Biol Ther (2003) 1.45
Solvothermal synthesis and photoreactivity of anatase TiO(2) nanosheets with dominant {001} facets. J Am Chem Soc (2009) 1.45
Quantification of heparan sulfate disaccharides using ion-pairing reversed-phase microflow high-performance liquid chromatography with electrospray ionization trap mass spectrometry. Anal Chem (2009) 1.45
Nitric oxide induces CD4+CD25+ Foxp3 regulatory T cells from CD4+CD25 T cells via p53, IL-2, and OX40. Proc Natl Acad Sci U S A (2007) 1.45
Study of stone composition changes in melamine-related urinary calculi and its clinical significance. Urology (2011) 1.44
Participation of miR-200 in pulmonary fibrosis. Am J Pathol (2011) 1.43
Complement activation is involved in renal damage in human antineutrophil cytoplasmic autoantibody associated pauci-immune vasculitis. J Clin Immunol (2008) 1.42
Similarities and differences between smoking-related gene expression in nasal and bronchial epithelium. Physiol Genomics (2009) 1.42
Suppression of inhibitor of differentiation 2, a target of mutant p53, is required for gain-of-function mutations. Cancer Res (2008) 1.41
Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis. PLoS Genet (2010) 1.41
Depression recognition using resting-state and event-related fMRI signals. Magn Reson Imaging (2012) 1.41
On the true photoreactivity order of {001}, {010}, and {101} facets of anatase TiO2 crystals. Angew Chem Int Ed Engl (2011) 1.41
Differentially expressed genes between primary cancer and paired lymph node metastases predict clinical outcome of node-positive breast cancer patients. Breast Cancer Res Treat (2006) 1.40
C-reactive protein and ischemia in users and nonusers of beta-blockers and statins: data from the Heart and Soul Study. Circulation (2003) 1.40
Genome-wide association scan for stature in Chinese: evidence for ethnic specific loci. Hum Genet (2008) 1.39
Complement deposition in renal histopathology of patients with ANCA-associated pauci-immune glomerulonephritis. Nephrol Dial Transplant (2008) 1.37
Clinicopathological characteristics and outcomes of patients with crescentic lupus nephritis. Kidney Int (2009) 1.37
Clinical characteristics of the autumn-winter type scrub typhus cases in south of Shandong province, northern China. BMC Infect Dis (2009) 1.36
Fibroblast growth factor 2 promotes endothelial differentiation of adipose tissue-derived stem cells. J Sex Med (2008) 1.35
Loss-of-function mutations in the PRPS1 gene cause a type of nonsyndromic X-linked sensorineural deafness, DFN2. Am J Hum Genet (2010) 1.34
KLF4 gene expression is inhibited by the notch signaling pathway that controls goblet cell differentiation in mouse gastrointestinal tract. Am J Physiol Gastrointest Liver Physiol (2008) 1.33
Genomic analysis of anti-hepatitis B virus (HBV) activity by small interfering RNA and lamivudine in stable HBV-producing cells. J Virol (2005) 1.32
Tubulointerstitial lesions of patients with lupus nephritis classified by the 2003 International Society of Nephrology and Renal Pathology Society system. Kidney Int (2010) 1.32
Assessment of the gene expression profile of differentiated and dedifferentiated human fetal chondrocytes by microarray analysis. Arthritis Rheum (2002) 1.32
Interaction between PLA2R1 and HLA-DQA1 variants associates with anti-PLA2R antibodies and membranous nephropathy. J Am Soc Nephrol (2013) 1.31
Amorphous TiO(2) nanotube arrays for low-temperature oxygen sensors. Nanotechnology (2008) 1.30
miR-21 regulates chronic hypoxia-induced pulmonary vascular remodeling. Am J Physiol Lung Cell Mol Physiol (2012) 1.29
FSH and testosterone signaling in Sertoli cells. Reproduction (2005) 1.28
PAI-1 inhibits neutrophil efferocytosis. Proc Natl Acad Sci U S A (2008) 1.27
Apoptosis genes in human alveolar macrophages infected with virulent or attenuated Mycobacterium tuberculosis: a pivotal role for tumor necrosis factor. Am J Respir Cell Mol Biol (2003) 1.27