Published in Science on June 20, 2014
Transition states and cell fate decisions in epigenetic landscapes. Nat Rev Genet (2016) 0.80
Inferring Cell-State Transition Dynamics from Lineage Trees and Endpoint Single-Cell Measurements. Cell Syst (2016) 0.80
Variation is function: Are single cell differences functionally important?: Testing the hypothesis that single cell variation is required for aggregate function. Bioessays (2015) 0.80
Computational analysis of signaling patterns in single cells. Semin Cell Dev Biol (2014) 0.78
Simultaneous Metabolite, Protein, Lipid Extraction (SIMPLEX): A Combinatorial Multimolecular Omics Approach for Systems Biology. Mol Cell Proteomics (2016) 0.77
Cellular Deconstruction: Finding Meaning in Individual Cell Variation. Trends Cell Biol (2015) 0.76
Adipocytes, like their progenitors, contribute to inflammation of adipose tissues through promotion of Th-17 cells and activation of monocytes, in obese subjects. Adipocyte (2016) 0.75
Using SRM-MS to quantify nuclear protein abundance differences between adipose tissue depots of insulin-resistant mice. J Lipid Res (2015) 0.75
Deep phenotyping unveils hidden traits and genetic relations in subtle mutants. Nat Commun (2016) 0.75
Measuring Gli2 Phosphorylation by Selected Reaction Monitoring Mass Spectrometry. Methods Mol Biol (2015) 0.75
Cross-linked matrix rigidity and soluble retinoids synergize in nuclear lamina regulation of stem cell differentiation. Mol Biol Cell (2017) 0.75
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature (2011) 11.44
Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol (2006) 11.36
Dynamics of fat cell turnover in humans. Nature (2008) 9.80
Fat and beyond: the diverse biology of PPARgamma. Annu Rev Biochem (2008) 9.56
Direct cell reprogramming is a stochastic process amenable to acceleration. Nature (2009) 8.71
Transcriptome-wide noise controls lineage choice in mammalian progenitor cells. Nature (2008) 7.60
Interlinked fast and slow positive feedback loops drive reliable cell decisions. Science (2005) 6.88
Full dynamic range proteome analysis of S. cerevisiae by targeted proteomics. Cell (2009) 6.54
C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway. Genes Dev (2002) 6.46
Mammalian heart renewal by pre-existing cardiomyocytes. Nature (2012) 5.56
Tunability and noise dependence in differentiation dynamics. Science (2007) 5.23
Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure. Cell (2012) 4.88
PPARgamma and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale. Genes Dev (2008) 4.83
Peroxisome proliferator-activated receptor (PPAR) gamma: adipose-predominant expression and induction early in adipocyte differentiation. Endocrinology (1994) 4.67
Tracking adipogenesis during white adipose tissue development, expansion and regeneration. Nat Med (2013) 3.86
Dedifferentiation of committed epithelial cells into stem cells in vivo. Nature (2013) 2.85
Ultrasensitivity in the Regulation of Cdc25C by Cdk1. Mol Cell (2011) 2.27
Non-genetic cell-to-cell variability and the consequences for pharmacology. Curr Opin Chem Biol (2009) 2.05
Continuous nucleocytoplasmic shuttling underlies transcriptional activation of PPARgamma by FABP4. Biochemistry (2007) 1.58
OP9 mouse stromal cells rapidly differentiate into adipocytes: characterization of a useful new model of adipogenesis. J Lipid Res (2005) 1.58
Weighing in on adipocyte precursors. Cell Metab (2013) 1.43
Human dedifferentiated adipocytes show similar properties to bone marrow-derived mesenchymal stem cells. Stem Cells (2012) 1.38
The developmental origins of adipose tissue. Development (2013) 1.24
Measuring committed preadipocytes in human adipose tissue from severely obese patients by using adipocyte fatty acid binding protein. Am J Physiol Regul Integr Comp Physiol (2004) 1.16
Parallel adaptive feedback enhances reliability of the Ca2+ signaling system. Proc Natl Acad Sci U S A (2011) 1.01
Neuroblastoma phox2b variants stimulate proliferation and dedifferentiation of immature sympathetic neurons. J Neurosci (2010) 1.00
Consecutive positive feedback loops create a bistable switch that controls preadipocyte-to-adipocyte conversion. Cell Rep (2012) 0.93
Transient noise amplification and gene expression synchronization in a bistable mammalian cell-fate switch. Cell Rep (2012) 0.85
Lipin1 regulates PPARγ transcriptional activity. Biochem J (2013) 0.82