The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression.

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🔗 View Article (PMID 24952462)

Published in Nat Cell Biol on June 22, 2014

Authors

Gavin Whissell1, Elisa Montagni2, Paola Martinelli3, Xavier Hernando-Momblona1, Marta Sevillano1, Peter Jung1, Carme Cortina1, Alexandre Calon1, Anna Abuli4, Antoni Castells5, Sergi Castellvi-Bel5, Ana Silvina Nacht6, Elena Sancho1, Camille Stephan-Otto Attolini1, Guillermo P Vicent6, Francisco X Real7, Eduard Batlle8

Author Affiliations

1: Institute for Research in Biomedicine (IRB Barcelona), 08028 Barcelona, Spain.
2: 1] Institute for Research in Biomedicine (IRB Barcelona), 08028 Barcelona, Spain [2].
3: 1] Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain [2].
4: 1] Department of Gastroenterology, Hospital Clínic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, 08036 Barcelona, Catalonia, Spain [2] Department of Gastroenterology, Hospital del Mar-IMIM (Hospital del Mar Medical Research Centre), Pompeu Fabra University, 08003 Barcelona, Catalonia, Spain.
5: Department of Gastroenterology, Hospital Clínic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, 08036 Barcelona, Catalonia, Spain.
6: Centre de Regulació Genòmica (CRG), Universitat Pompeu Fabra (UPF), E-08003 Barcelona, Spain.
7: 1] Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain [2] Universitat Pompeu Fabra, 08003 Barcelona, Spain.
8: 1] Institute for Research in Biomedicine (IRB Barcelona), 08028 Barcelona, Spain [2] Institució Catalana de Recerca i Estudis Avançats (ICREA), 08010 Barcelona, Spain.

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