The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival.

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Published in Sci Rep on September 02, 2016

Authors

Shane P Duggan1,2, Fiona M Behan3, Murat Kirca4, Abdul Zaheer4, Sarah A McGarrigle5, John V Reynolds5, Gisela M F Vaz6, Mathias O Senge6, Dermot Kelleher1,2

Author Affiliations

1: Department of Medicine, Division of Gastroenterology, University of British Columbia, 2775 Laurel Street, Vancouver, British Columbia, Canada.
2: Life Science Institute, 2350 Health Sciences Mall, Vancouver, British Columbia, Canada.
3: Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin, St James' Hospital, Dublin, Ireland.
4: Department of Gastroenterology, St James' Hospital, Dublin, Ireland.
5: Department of Surgery, Institute of Molecular Medicine, Trinity College Dublin, St James' Hospital, Dublin 8, Ireland.
6: Medicinal Chemistry, Trinity Translational Medicine Institute, Trinity College Dublin, the University of Dublin, St James' Hospital, Dublin 8, Ireland.

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