Published in J Biol Chem on June 24, 2014
Sites and functional consequence of VDAC-alkylphenol anesthetic interactions. FEBS Lett (2014) 0.84
Solid-state NMR, electrophysiology and molecular dynamics characterization of human VDAC2. J Biomol NMR (2014) 0.82
Current state of theoretical and experimental studies of the voltage-dependent anion channel (VDAC). Biochim Biophys Acta (2016) 0.79
N-helix and Cysteines Inter-regulate Human Mitochondrial VDAC-2 Function and Biochemistry. J Biol Chem (2015) 0.78
Conductance hysteresis in the voltage-dependent anion channel. Eur Biophys J (2015) 0.77
Impact of Dendrimer Terminal Group Chemistry on Blockage of the Anthrax Toxin Channel: A Single Molecule Study. Toxins (Basel) (2016) 0.75
Voltage Dependence of Conformational Dynamics and Subconducting States of VDAC-1. Biophys J (2016) 0.75
Mitochondrial VDAC1: A Key Gatekeeper as Potential Therapeutic Target. Front Physiol (2017) 0.75
On the different sources of cooperativity in pH titrating sites of a membrane protein channel. Eur Phys J E Soft Matter (2016) 0.75
Aberrantly large single-channel conductance of polyhistidine arm-containing protein nanopores. Biochemistry (2017) 0.75
Scalable molecular dynamics with NAMD. J Comput Chem (2005) 59.49
CHARMM: the biomolecular simulation program. J Comput Chem (2009) 27.71
Oxygen-derived free radicals in postischemic tissue injury. N Engl J Med (1985) 11.68
Update of the CHARMM all-atom additive force field for lipids: validation on six lipid types. J Phys Chem B (2010) 8.70
Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury. Physiol Rev (2008) 5.52
Reconstitution in planar lipid bilayers of a voltage-dependent anion-selective channel obtained from paramecium mitochondria. J Membr Biol (1976) 5.01
Myocardial reperfusion: a double-edged sword? J Clin Invest (1985) 4.12
Polymer inaccessible volume changes during opening and closing of a voltage-dependent ionic channel. Nature (1986) 3.89
Protonation dynamics of the alpha-toxin ion channel from spectral analysis of pH-dependent current fluctuations. Biophys J (1995) 3.27
How membrane proteins sense voltage. Nat Rev Mol Cell Biol (2008) 2.94
Voltage gating in the mitochondrial channel, VDAC. J Membr Biol (1989) 2.92
The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating. Proc Natl Acad Sci U S A (2008) 2.82
Automated builder and database of protein/membrane complexes for molecular dynamics simulations. PLoS One (2007) 2.65
Warburg, me and Hexokinase 2: Multiple discoveries of key molecular events underlying one of cancers' most common phenotypes, the "Warburg Effect", i.e., elevated glycolysis in the presence of oxygen. J Bioenerg Biomembr (2007) 2.47
VDAC, a multi-functional mitochondrial protein regulating cell life and death. Mol Aspects Med (2010) 2.36
In self-defence: hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death. Biochem J (2004) 2.30
Selectivity changes in site-directed mutants of the VDAC ion channel: structural implications. Science (1990) 2.15
Current noise reveals protonation kinetics and number of ionizable sites in an open protein ion channel. Phys Rev Lett (1993) 2.09
VDAC channels mediate and gate the flow of ATP: implications for the regulation of mitochondrial function. Biophys J (1997) 2.09
The relationship between mitochondrial shape and function and the cytoskeleton. Biochim Biophys Acta (2006) 2.02
VDAC, a channel in the outer mitochondrial membrane. Ion Channels (1996) 1.97
Regulation of metabolite flux through voltage-gating of VDAC channels. J Membr Biol (1997) 1.94
ATP transport through a single mitochondrial channel, VDAC, studied by current fluctuation analysis. Biophys J (1998) 1.86
ATP flux is controlled by a voltage-gated channel from the mitochondrial outer membrane. J Biol Chem (1996) 1.84
Regulation of hexokinase binding to VDAC. J Bioenerg Biomembr (2008) 1.73
VDAC regulation: role of cytosolic proteins and mitochondrial lipids. J Bioenerg Biomembr (2008) 1.60
NADH regulates the gating of VDAC, the mitochondrial outer membrane channel. J Biol Chem (1994) 1.53
Intracellular pH during "chemical hypoxia" in cultured rat hepatocytes. Protection by intracellular acidosis against the onset of cell death. J Clin Invest (1989) 1.53
Mapping of residues forming the voltage sensor of the voltage-dependent anion-selective channel. Proc Natl Acad Sci U S A (1993) 1.52
Conformational changes in the mitochondrial channel protein, VDAC, and their functional implications. J Struct Biol (1998) 1.51
The mitochondrial outer membrane channel, VDAC, is regulated by a synthetic polyanion. Biochim Biophys Acta (1987) 1.49
Voltage gating of VDAC is regulated by nonlamellar lipids of mitochondrial membranes. J Biol Chem (2006) 1.49
Peptide-specific antibodies as probes of the topography of the voltage-gated channel in the mitochondrial outer membrane of Neurospora crassa. J Biol Chem (1995) 1.42
The topology of VDAC as probed by biotin modification. J Biol Chem (1998) 1.39
Heart muscle viability following hypoxia: protective effect of acidosis. Science (1973) 1.30
The sensor regions of VDAC are translocated from within the membrane to the surface during the gating processes. Biophys J (1998) 1.26
Opposite effects of microtubule-stabilizing and microtubule-destabilizing drugs on biogenesis of mitochondria in mammalian cells. J Cell Sci (2001) 1.25
Disruption of the hexokinase-VDAC complex for tumor therapy. Oncogene (2008) 1.24
Structure-function relationships in feedback regulation of energy fluxes in vivo in health and disease: mitochondrial interactosome. Biochim Biophys Acta (2010) 1.14
Functional dynamics in the voltage-dependent anion channel. Proc Natl Acad Sci U S A (2010) 1.13
Affixing N-terminal α-helix to the wall of the voltage-dependent anion channel does not prevent its voltage gating. J Biol Chem (2012) 1.13
Positive cooperativity without domains or subunits in a monomeric membrane channel. Proc Natl Acad Sci U S A (2000) 1.10
Mitochondrial hexokinases: guardians of the mitochondria. Cell Cycle (2005) 1.10
VDAC inhibition by tubulin and its physiological implications. Biochim Biophys Acta (2011) 1.08
Phosphorylation of voltage-dependent anion channel by serine/threonine kinases governs its interaction with tubulin. PLoS One (2011) 1.07
The native conformation of the human VDAC1 N terminus. Angew Chem Int Ed Engl (2010) 1.05
Circular dichroism studies of the mitochondrial channel, VDAC, from Neurospora crassa. Biophys J (1996) 1.04
Regulation of respiration in brain mitochondria and synaptosomes: restrictions of ADP diffusion in situ, roles of tubulin, and mitochondrial creatine kinase. Mol Cell Biochem (2008) 1.04
Effects of metabolic acidosis on viability of cells exposed to anoxia. Am J Physiol (1985) 1.02
Protection by acidotic pH and fructose against lethal injury to rat hepatocytes from mitochondrial inhibitors, ionophores and oxidant chemicals. Biochem Biophys Res Commun (1990) 1.02
Voltage dependence and ion selectivity of the mitochondrial channel, VDAC, are modified by succinic anhydride. J Membr Biol (1985) 1.02
Structure of the voltage dependent anion channel: state of the art. J Bioenerg Biomembr (2008) 1.01
Tubulin-blocked state of VDAC studied by polymer and ATP partitioning. FEBS Lett (2011) 0.99
The voltage-gating process of the voltage-dependent anion channel is sensitive to ion flow. Biophys J (1998) 0.97
Structural asymmetry in the magnesium channel CorA points to sequential allosteric regulation. Proc Natl Acad Sci U S A (2012) 0.96
Lipid dynamics and protein-lipid interactions in 2D crystals formed with the β-barrel integral membrane protein VDAC1. J Am Chem Soc (2012) 0.95
The voltage-dependent anion selective channel 1 (VDAC1) topography in the mitochondrial outer membrane as detected in intact cell. PLoS One (2013) 0.94
Evidence for titratable gating charges controlling the voltage dependence of the outer mitochondrial membrane channel, VDAC. J Membr Biol (1985) 0.94
Intracellular pH and Ca2+ homeostasis in the pH paradox of reperfusion injury to neonatal rat cardiac myocytes. Am J Physiol (1993) 0.94
Structure-based analysis of VDAC1: N-terminus location, translocation, channel gating and association with anti-apoptotic proteins. Biochem J (2012) 0.93
Probing the orientation of yeast VDAC1 in vivo. FEBS Lett (2009) 0.93
Molecular model of hexokinase binding to the outer mitochondrial membrane porin (VDAC1): Implication for the design of new cancer therapies. Mitochondrion (2011) 0.91
The pH paradox in ischemia-reperfusion injury to cardiac myocytes. EXS (1996) 0.88
ATP transport through VDAC and the VDAC-tubulin complex probed by equilibrium and nonequilibrium MD simulations. Biochemistry (2013) 0.86
Purification and properties of the voltage-dependent anion channel of the outer mitochondrial membrane. J Bioenerg Biomembr (1989) 0.86
Redistribution of the electric field within the pore contributes to the voltage-dependence of mitochondrial porin channel. Biochim Biophys Acta (1990) 0.85
The mitochondrial voltage-dependent channel, VDAC, is modified asymmetrically by succinic anhydride. J Membr Biol (1985) 0.82
The pH paradox in the pathophysiology of reperfusion injury to rat neonatal cardiac myocytes. Ann N Y Acad Sci (1994) 0.81
The gate of mitochondrial porin channel is controlled by a number of negative and positive charges. FEBS Lett (1989) 0.79
Electrostatics explains the shift in VDAC gating with salt activity gradient. Biophys J (2002) 0.78