Pulmonary infection with hypervirulent Mycobacteria reveals a crucial role for the P2X7 receptor in aggressive forms of tuberculosis.

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Published in PLoS Pathog on July 03, 2014

Authors

Eduardo P Amaral1, Simone C M Ribeiro2, Verônica R Lanes2, Fabrício M Almeida2, Marcelle R M de Andrade2, Caio Cesar Barbosa Bomfim1, Erika M Salles1, Karina R Bortoluci3, Robson Coutinho-Silva4, Mario H Hirata5, José M Alvarez1, Elena B Lasunskaia2, Maria Regina D'Império-Lima1

Author Affiliations

1: Departamento de Imunologia, Instituto de Ciências Biomédicas (ICB), Universidade de São Paulo (USP), São Paulo, São Paulo, Brazil.
2: Laboratório de Biologia do Reconhecer, Universidade Estadual do Norte Fluminense (UENF), Campos dos Goytacazes, Rio de Janeiro, Brazil.
3: Centro de Terapia Celular e Molecular, Departamento de Ciências Biológicas, Universidade Federal de São Paulo, São Paulo, São Paulo, Brazil.
4: Programa de Imunobiologia, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil; Instituto National de Ciência e Tecnologia para Pesquisa Translacional em Saúde e Meio Ambiente da Região Amazônica, Rio de Janeiro, Rio de Janeiro, Brazil.
5: Departamento de Química e Toxicologia Clínica, Faculdade de Ciências Farmacêuticas (FCT), University of São Paulo, São Paulo, São Paulo, Brazil.

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