Published in Immunobiology on March 16, 2013
Ion channels in innate and adaptive immunity. Annu Rev Immunol (2015) 1.99
Pulmonary infection with hypervirulent Mycobacteria reveals a crucial role for the P2X7 receptor in aggressive forms of tuberculosis. PLoS Pathog (2014) 0.98
Purinergic signalling and immune cells. Purinergic Signal (2014) 0.94
Cholera toxin enhances vaccine-induced protection against Mycobacterium tuberculosis challenge in mice. PLoS One (2013) 0.84
The inflammasome and danger molecule signaling: at the crossroads of inflammation and pathogen persistence in the oral cavity. Periodontol 2000 (2015) 0.78
Molecular characterization and expression analysis of ATP-gated P2X7 receptor involved in Japanese flounder (Paralichthys olivaceus) innate immune response. PLoS One (2014) 0.77
P2X71513 A>C Polymorphism Confers Increased Risk of Extrapulmonary Tuberculosis: A Meta-analysis of Case-Control Studies. Curr Genomics (2015) 0.75
Single Nucleotide Polymorphisms in P2X7 Gene Are Associated with Serum Immunoglobulin G Responses to Mycobacterium tuberculosis in Tuberculosis Patients. Dis Markers (2015) 0.75
A haplotype spanning P2X7R, P2X4R and CAMKK2 may mark susceptibility to pulmonary non-tuberculous mycobacterial disease. Immunogenetics (2017) 0.75
Anti-inflammatory compounds of plant origin. Part II. modulation of pro-inflammatory cytokines, chemokines and adhesion molecules. Planta Med (2004) 1.49
Connecting TNF-alpha signaling pathways to iNOS expression in a mouse model of Alzheimer's disease: relevance for the behavioral and synaptic deficits induced by amyloid beta protein. J Neurosci (2007) 1.44
Transplanted bone marrow cells repair heart tissue and reduce myocarditis in chronic chagasic mice. Am J Pathol (2004) 1.32
The anti-inflammatory mechanisms of Hsp70. Front Immunol (2012) 1.31
Anti-inflammatory effects of compounds alpha-humulene and (-)-trans-caryophyllene isolated from the essential oil of Cordia verbenacea. Eur J Pharmacol (2007) 1.21
Mycobacterium tuberculosis heat-shock protein 70 impairs maturation of dendritic cells from bone marrow precursors, induces interleukin-10 production and inhibits T-cell proliferation in vitro. Immunology (2007) 1.19
Kinin B1 receptors: key G-protein-coupled receptors and their role in inflammatory and painful processes. Br J Pharmacol (2004) 1.17
Activity of novel quinoxaline-derived chalcones on in vitro glioma cell proliferation. Eur J Med Chem (2011) 1.14
Loss of lysophosphatidylcholine acyltransferase 1 leads to photoreceptor degeneration in rd11 mice. Proc Natl Acad Sci U S A (2010) 1.10
Caffeic acid derivatives: in vitro and in vivo anti-inflammatory properties. Free Radic Res (2004) 1.09
Activation of ERK1/2 by extracellular nucleotides in macrophages is mediated by multiple P2 receptors independently of P2X7-associated pore or channel formation. Br J Pharmacol (2006) 1.08
Transscleral-RPE permeability of PEDF and ovalbumin proteins: implications for subconjunctival protein delivery. Invest Ophthalmol Vis Sci (2005) 1.07
Kinin B1 receptor up-regulation after lipopolysaccharide administration: role of proinflammatory cytokines and neutrophil influx. J Immunol (2004) 1.06
Tumor immunosuppressive environment: effects on tumor-specific and nontumor antigen immune responses. Expert Rev Anticancer Ther (2009) 1.04
Relevance of tumour necrosis factor-alpha for the inflammatory and nociceptive responses evoked by carrageenan in the mouse paw. Br J Pharmacol (2006) 1.03
Activation of the P2X(7) receptor triggers the elimination of Toxoplasma gondii tachyzoites from infected macrophages. Microbes Infect (2010) 1.03
Host-cell lipid rafts: a safe door for micro-organisms? Biol Cell (2010) 1.02
Effects of different mesenchymal stromal cell sources and delivery routes in experimental emphysema. Respir Res (2014) 0.99
Behavioral effects of taurine pretreatment in zebrafish acutely exposed to ethanol. Neuropharmacology (2012) 0.98
An inorganic iron complex that inhibits wild-type and an isoniazid-resistant mutant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis. Chem Commun (Camb) (2004) 0.97
Lipopolysaccharide-induced lung injury: role of P2X7 receptor. Respir Physiol Neurobiol (2011) 0.97
Inducible heat shock protein 70 expression as a potential predictive marker of metastasis in breast tumors. Cell Stress Chaperones (2006) 0.96
Extracellular ATP induces cell death in CD4+/CD8+ double-positive thymocytes in mice infected with Trypanosoma cruzi. Microbes Infect (2003) 0.95
Cloning and expression of functional shikimate dehydrogenase (EC 1.1.1.25) from Mycobacterium tuberculosis H37Rv. Protein Expr Purif (2002) 0.95
Impaired in vivo CD4+ T cell expansion and differentiation in aged mice is not solely due to T cell defects: decreased stimulation by aged dendritic cells. Mech Ageing Dev (2011) 0.95
The use of kinin B1 and B2 receptor knockout mice and selective antagonists to characterize the nociceptive responses caused by kinins at the spinal level. Neuropharmacology (2002) 0.95
Doxycycline-mediated inhibition of choroidal neovascularization. Invest Ophthalmol Vis Sci (2009) 0.95
Prolonged survival of allografts induced by mycobacterial Hsp70 is dependent on CD4+CD25+ regulatory T cells. PLoS One (2010) 0.95
Human granulocyte colony stimulating factor (hG-CSF): cloning, overexpression, purification and characterization. Microb Cell Fact (2008) 0.95
Protective immune response against methicillin resistant Staphylococcus aureus in a murine model using a DNA vaccine approach. Vaccine (2003) 0.95
Crystallographic and pre-steady-state kinetics studies on binding of NADH to wild-type and isoniazid-resistant enoyl-ACP(CoA) reductase enzymes from Mycobacterium tuberculosis. J Mol Biol (2006) 0.93
The effects of diacerhein on mechanical allodynia in inflammatory and neuropathic models of nociception in mice. Anesth Analg (2005) 0.93
Identification of Rv3852 as a nucleoid-associated protein in Mycobacterium tuberculosis. Microbiology (2009) 0.92
Anti-inflammatory and anti-allergic properties of the essential oil and active compounds from Cordia verbenacea. J Ethnopharmacol (2006) 0.90
Gastrin-releasing peptide receptor (GRPR) mediates chemotaxis in neutrophils. Proc Natl Acad Sci U S A (2011) 0.90
Seizures induced by pentylenetetrazole in the adult zebrafish: a detailed behavioral characterization. PLoS One (2013) 0.89
C terminus of the P2X7 receptor: treasure hunting. Purinergic Signal (2011) 0.89
7-Ketocholesterol induces inflammation and angiogenesis in vivo: a novel rat model. PLoS One (2013) 0.89
Modulation of P2X(7) purinergic receptor in macrophages by Leishmania amazonensis and its role in parasite elimination. Microbes Infect (2009) 0.88
Slow-onset inhibition of 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis by an inorganic complex. Curr Pharm Des (2006) 0.88
Substrate specificity and kinetic mechanism of purine nucleoside phosphorylase from Mycobacterium tuberculosis. Arch Biochem Biophys (2009) 0.88
Antinociceptive Activity of Trichilia catigua Hydroalcoholic Extract: New Evidence on Its Dopaminergic Effects. Evid Based Complement Alternat Med (2011) 0.88
Modulation of intercellular communication in macrophages: possible interactions between GAP junctions and P2 receptors. J Cell Sci (2004) 0.88
Role of CXCR2 and TRPV1 in functional, inflammatory and behavioural changes in the rat model of cyclophosphamide-induced haemorrhagic cystitis. Br J Pharmacol (2014) 0.88
Neuropathic pain-like behavior after brachial plexus avulsion in mice: the relevance of kinin B1 and B2 receptors. J Neurosci (2008) 0.88
Alterations in dendritic cell function in aged mice: potential implications for immunotherapy design. Biogerontology (2008) 0.88
Extracellular ATP induces cell death in human intestinal epithelial cells. Biochim Biophys Acta (2012) 0.88
Expression of purinergic receptors and modulation of P2X7 function by the inflammatory cytokine IFNgamma in human epithelial cells. Biochim Biophys Acta (2009) 0.88
Effects of the compounds MV8608 and MV8612 obtained from Mandevilla velutina in the model of hemorrhagic cystitis induced by cyclophosphamide in rats. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.88
Mesenchymal stem cells from different murine tissues have differential capacity to metabolize extracellular nucleotides. J Cell Biochem (2014) 0.87
Gap junction reduction in cardiomyocytes following transforming growth factor-beta treatment and Trypanosoma cruzi infection. Mem Inst Oswaldo Cruz (2009) 0.87
The kinetic mechanism of human uridine phosphorylase 1: Towards the development of enzyme inhibitors for cancer chemotherapy. Arch Biochem Biophys (2010) 0.87
Characterization of ATP-induced cell death in the GL261 mouse glioma. J Cell Biochem (2010) 0.87
HLA-A, -B, and -DRB1 allelic and haplotypic diversity in a sample of bone marrow volunteer donors from Rio Grande do Sul State, Brazil. Hum Immunol (2011) 0.87
Chorismate synthase: an attractive target for drug development against orphan diseases. Curr Drug Targets (2007) 0.86
Characterizing the presence and sensitivity of the P2X7 receptor in different compartments of the gut. J Innate Immun (2012) 0.86
Leukotriene B4 modulates P2X7 receptor-mediated Leishmania amazonensis elimination in murine macrophages. J Immunol (2014) 0.86
Prophylactic systemic P2X7 receptor blockade prevents experimental colitis. Biochim Biophys Acta (2013) 0.86
Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein (ACP) reductase: kinetic and chemical mechanisms. Biochemistry (2006) 0.86
In vivo up-regulation of kinin B1 receptors after treatment with Porphyromonas gingivalis lipopolysaccharide in rat paw. J Pharmacol Exp Ther (2009) 0.86
Association between bisphosphonates and jaw osteonecrosis: a study in Wistar rats. Head Neck (2011) 0.86
The two chorismate mutases from both Mycobacterium tuberculosis and Mycobacterium smegmatis: biochemical analysis and limited regulation of promoter activity by aromatic amino acids. J Bacteriol (2007) 0.86
Evaluation of salivary endothelin-1 levels in oral squamous cell carcinoma and oral leukoplakia. Regul Pept (2010) 0.86
Probing potassium channel function in vivo by intracellular delivery of antibodies in a rat model of retinal neurodegeneration. Proc Natl Acad Sci U S A (2010) 0.86
Synergistic effects of celecoxib and bupropion in a model of chronic inflammation-related depression in mice. PLoS One (2013) 0.86
Extracellular Hsp70 inhibits pro-inflammatory cytokine production by IL-10 driven down-regulation of C/EBPβ and C/EBPδ. Int J Hyperthermia (2013) 0.85
One-step purification of 5-enolpyruvylshikimate-3-phosphate synthase enzyme from Mycobacterium tuberculosis. Protein Expr Purif (2003) 0.85
Cytokines and neutrophils as important mediators of platelet-activating factor-induced kinin B1 receptor expression. Br J Pharmacol (2005) 0.85
Kinin B1 receptors mediate depression-like behavior response in stressed mice treated with systemic E. coli lipopolysaccharide. J Neuroinflammation (2010) 0.85
Selective NTPDase2 expression modulates in vivo rat glioma growth. Cancer Sci (2009) 0.85
Discovery of new inhibitors of Mycobacterium tuberculosis InhA enzyme using virtual screening and a 3D-pharmacophore-based approach. J Chem Inf Model (2013) 0.84
The influences of CD14 -260C>T polymorphism on survival in ICU critically ill patients. Immunol Invest (2009) 0.84
Effects of the hydroalcoholic extract of Phyllanthus niruri and its isolated compounds on cyclophosphamide-induced hemorrhagic cystitis in mouse. Naunyn Schmiedebergs Arch Pharmacol (2011) 0.84
Cloning, overexpression, and purification of functional human purine nucleoside phosphorylase. Protein Expr Purif (2003) 0.84
Self-tolerance checkpoints in CD4 T cells specific for a peptide derived from the B cell antigen receptor. J Immunol (2011) 0.84
Altered responsiveness to extracellular ATP enhances acetaminophen hepatotoxicity. Cell Commun Signal (2013) 0.84
Purinergic receptor agonists modulate phagocytosis and clearance of apoptotic cells in macrophages. Immunobiology (2010) 0.83
CD14 expression in the first 24h of sepsis: effect of -260C>T CD14 SNP. Immunol Invest (2008) 0.83
Functional shikimate dehydrogenase from Mycobacterium tuberculosis H37Rv: purification and characterization. Protein Expr Purif (2005) 0.83
Role of IL-15 and IL-21 in viral immunity: applications for vaccines and therapies. Expert Rev Vaccines (2009) 0.83
Differential modulation of ATP-induced P2X7-associated permeabilities to cations and anions of macrophages by infection with Leishmania amazonensis. PLoS One (2011) 0.83
Overexpression of ATP-activated P2X7 receptors in the intestinal mucosa is implicated in the pathogenesis of Crohn's disease. Inflamm Bowel Dis (2014) 0.83
Cannabinoid agonists inhibit neuropathic pain induced by brachial plexus avulsion in mice by affecting glial cells and MAP kinases. PLoS One (2011) 0.83
Kinetics and crystal structure of human purine nucleoside phosphorylase in complex with 7-methyl-6-thio-guanosine. Arch Biochem Biophys (2005) 0.82
Effect of novel selective non-peptide kinin B(1) receptor antagonists on mouse pleurisy induced by carrageenan. Peptides (2006) 0.82
Porphyromonas gingivalis fimbriae dampen P2X7-dependent interleukin-1β secretion. J Innate Immun (2014) 0.82
TNF -308G > a promoter polymorphism (rs1800629) and outcome from critical illness. Braz J Infect Dis (2011) 0.82
DAHP synthase from Mycobacterium tuberculosis H37Rv: cloning, expression, and purification of functional enzyme. Protein Expr Purif (2005) 0.82
Analysis of the NTPDase and ecto-5'-nucleotidase profiles in serum-limited Trichomonas vaginalis. Mem Inst Oswaldo Cruz (2012) 0.82
Is increasing urinary albumin a better marker for microvascular than for macrovascular complication of type 2 diabetes mellitus? Nephron Clin Pract (2005) 0.82
Oxidative stress and delta-ALA-D activity in chronic renal failure patients. Biomed Pharmacother (2007) 0.82
Lycorine induces cell death in the amitochondriate parasite, Trichomonas vaginalis, via an alternative non-apoptotic death pathway. Phytochemistry (2011) 0.81