Published in Kidney Int Suppl (2011) on December 01, 2013
Chronic kidney disease of unknown aetiology and ground-water ionicity: study based on Sri Lanka. Environ Geochem Health (2014) 1.00
Serum phosphorus and association with anemia among a large diverse population with and without chronic kidney disease. Nephrol Dial Transplant (2015) 0.78
Where is the link between mineral bone markers and cardiovascular disease in CKD? Clin Kidney J (2015) 0.77
Phosphate, fibroblast growth factor 23 and retinopathy in chronic kidney disease: the Chronic Renal Insufficiency Cohort Study. Nephrol Dial Transplant (2015) 0.76
Approximation of Corrected Calcium Concentrations in Advanced Chronic Kidney Disease Patients with or without Dialysis Therapy. Nephron Extra (2015) 0.75
Accelerated ageing and renal dysfunction links lower socioeconomic status and dietary phosphate intake. Aging (Albany NY) (2016) 0.75
Dysregulation of phosphate metabolism and conditions associated with phosphate toxicity. Bonekey Rep (2015) 0.75
Urinary phosphorus excretion per creatinine clearance as a prognostic marker for progression of chronic kidney disease: a retrospective cohort study. BMC Nephrol (2015) 0.75
The Urinary Phosphate to Serum Fibroblast Growth Factor 23 Ratio Is a Useful Marker of Atherosclerosis in Early-Stage Chronic Kidney Disease. PLoS One (2016) 0.75
More than skin deep? Potential nicotinamide treatment applications in chronic kidney transplant recipients. World J Transplant (2016) 0.75
DNMT1 and HDAC2 Cooperate to Facilitate Aberrant Promoter Methylation in Inorganic Phosphate-Induced Endothelial-Mesenchymal Transition. PLoS One (2016) 0.75
Prevalence of chronic kidney disease in the United States. JAMA (2007) 38.98
Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature (1997) 13.77
Long-term consequences of kidney donation. N Engl J Med (2009) 10.17
FGF23 induces left ventricular hypertrophy. J Clin Invest (2011) 7.22
Prevalence of abnormal serum vitamin D, PTH, calcium, and phosphorus in patients with chronic kidney disease: results of the study to evaluate early kidney disease. Kidney Int (2006) 7.02
Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism. J Clin Invest (2004) 7.00
FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis. J Bone Miner Res (2003) 6.81
Regulation of fibroblast growth factor-23 signaling by klotho. J Biol Chem (2006) 6.50
Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney disease. J Am Soc Nephrol (2005) 5.76
Phosphate regulation of vascular smooth muscle cell calcification. Circ Res (2000) 5.18
Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease. Kidney Int (2011) 4.74
The parathyroid is a target organ for FGF23 in rats. J Clin Invest (2007) 4.47
Circulating concentration of FGF-23 increases as renal function declines in patients with chronic kidney disease, but does not change in response to variation in phosphate intake in healthy volunteers. Kidney Int (2003) 3.75
The serum protein alpha 2-Heremans-Schmid glycoprotein/fetuin-A is a systemically acting inhibitor of ectopic calcification. J Clin Invest (2003) 3.71
Smooth muscle cell phenotypic transition associated with calcification: upregulation of Cbfa1 and downregulation of smooth muscle lineage markers. Circ Res (2001) 3.50
Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23. Kidney Int (2001) 3.44
Targeted inactivation of Npt2 in mice leads to severe renal phosphate wasting, hypercalciuria, and skeletal abnormalities. Proc Natl Acad Sci U S A (1998) 3.24
Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular calcification in ESRD. J Am Soc Nephrol (2004) 3.22
Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system. Mol Endocrinol (2003) 3.15
Fully phosphorylated fetuin-A forms a mineral complex in the serum of rats with adenine-induced renal failure. Kidney Int (2009) 3.13
Dietary phosphorus regulates serum fibroblast growth factor-23 concentrations in healthy men. J Clin Endocrinol Metab (2006) 3.08
Direct evidence for a causative role of FGF23 in the abnormal renal phosphate handling and vitamin D metabolism in rats with early-stage chronic kidney disease. Kidney Int (2010) 3.04
Premature aging-like phenotype in fibroblast growth factor 23 null mice is a vitamin D-mediated process. FASEB J (2006) 2.99
Nanobacteria: an alternative mechanism for pathogenic intra- and extracellular calcification and stone formation. Proc Natl Acad Sci U S A (1998) 2.68
Vegetarian compared with meat dietary protein source and phosphorus homeostasis in chronic kidney disease. Clin J Am Soc Nephrol (2010) 2.67
Hyperphosphatemia-induced nanocrystals upregulate the expression of bone morphogenetic protein-2 and osteopontin genes in mouse smooth muscle cells in vitro. Kidney Int (2010) 2.61
Targeted deletion of Klotho in kidney distal tubule disrupts mineral metabolism. J Am Soc Nephrol (2012) 2.48
Klotho inhibits transforming growth factor-beta1 (TGF-beta1) signaling and suppresses renal fibrosis and cancer metastasis in mice. J Biol Chem (2011) 2.46
Reversal of mineral ion homeostasis and soft-tissue calcification of klotho knockout mice by deletion of vitamin D 1alpha-hydroxylase. Kidney Int (2009) 2.39
Structural basis of calcification inhibition by alpha 2-HS glycoprotein/fetuin-A. Formation of colloidal calciprotein particles. J Biol Chem (2003) 2.26
Diphosphonates inhibit formation of calcium phosphate crystals in vitro and pathological calcification in vivo. Science (1969) 2.20
Calcium phosphate crystals induce cell death in human vascular smooth muscle cells: a potential mechanism in atherosclerotic plaque destabilization. Circ Res (2008) 2.16
Role of hyperphosphatemia and 1,25-dihydroxyvitamin D in vascular calcification and mortality in fibroblastic growth factor 23 null mice. J Am Soc Nephrol (2007) 2.16
Dietary phosphorus acutely impairs endothelial function. J Am Soc Nephrol (2009) 2.09
Assessment of renal fibrosis with diffusion-weighted MR imaging: study with murine model of unilateral ureteral obstruction. Radiology (2010) 2.08
Human nephron number: implications for health and disease. Pediatr Nephrol (2011) 2.03
Effects of aging on glomerular function and number in living kidney donors. Kidney Int (2010) 1.92
The aging kidney. Kidney Int (2008) 1.85
Initial FGF23-mediated signaling occurs in the distal convoluted tubule. J Am Soc Nephrol (2009) 1.74
The phosphatonin pathway: new insights in phosphate homeostasis. Kidney Int (2004) 1.69
Dietary and genetic evidence for phosphate toxicity accelerating mammalian aging. FASEB J (2010) 1.58
Ablation of vitamin D signaling rescues bone, mineral, and glucose homeostasis in Fgf-23 deficient mice. Matrix Biol (2006) 1.56
Effects of dietary phosphate and calcium intake on fibroblast growth factor-23. Clin J Am Soc Nephrol (2010) 1.53
Cognition impairment in the genetic model of aging klotho gene mutant mice: a role of oxidative stress. FASEB J (2002) 1.52
Disruption of the klotho gene causes pulmonary emphysema in mice. Defect in maintenance of pulmonary integrity during postnatal life. Am J Respir Cell Mol Biol (2000) 1.43
Nanobacteria are mineralo fetuin complexes. PLoS Pathog (2008) 1.42
Fibroblast growth factor 23, cardiovascular disease risk factors, and phosphorus intake in the health professionals follow-up study. Clin J Am Soc Nephrol (2011) 1.36
Renal toxicity of phosphate in rats. Kidney Int (1980) 1.33
Effect of acute changes of serum phosphate on fibroblast growth factor (FGF)23 levels in humans. J Bone Miner Metab (2007) 1.31
Increased inorganic phosphate induces human endothelial cell apoptosis in vitro. Am J Physiol Renal Physiol (2008) 1.28
In vivo genetic evidence for suppressing vascular and soft-tissue calcification through the reduction of serum phosphate levels, even in the presence of high serum calcium and 1,25-dihydroxyvitamin d levels. Circ Cardiovasc Genet (2009) 1.26
Nanobacteria--propagating calcifying nanoparticles. Lett Appl Microbiol (2006) 1.25
Putative nanobacteria represent physiological remnants and culture by-products of normal calcium homeostasis. PLoS One (2009) 1.17
Characterization of granulations of calcium and apatite in serum as pleomorphic mineralo-protein complexes and as precursors of putative nanobacteria. PLoS One (2009) 1.16
Independent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopenia. J Clin Invest (1999) 1.16
Structural dynamics of a colloidal protein-mineral complex bestowing on calcium phosphate a high solubility in biological fluids. Biointerphases (2007) 1.16
Spontaneous precipitation of brushite in urine: evidence that brushite is the nidus of renal stones originating as calcium phosphate. Proc Natl Acad Sci U S A (1971) 1.15
The kidney and bisphosphonates. Bone (2011) 1.14
Nanobacteria: controversial pathogens in nephrolithiasis and polycystic kidney disease. Curr Opin Nephrol Hypertens (2001) 1.08
Fetuin-mineral complex reflects extraosseous calcification stress in CKD. J Am Soc Nephrol (2010) 1.08
Phosphonoformic acid prevents vascular smooth muscle cell calcification by inhibiting calcium-phosphate deposition. Arterioscler Thromb Vasc Biol (2009) 1.07
Calcium phosphate-induced renal epithelial injury and stone formation: involvement of reactive oxygen species. Kidney Int (2003) 1.05
RENAL DAMAGE FOLLOWING THE INGESTION OF A DIET CONTAINING AN EXCESS OF INORGANIC PHOSPHATE. J Exp Med (1935) 1.05
Phosphorylated fetuin-A-containing calciprotein particles are associated with aortic stiffness and a procalcific milieu in patients with pre-dialysis CKD. Nephrol Dial Transplant (2011) 1.02
A shielding topology stabilizes the early stage protein-mineral complexes of fetuin-A and calcium phosphate: a time-resolved small-angle X-ray study. Chembiochem (2009) 0.99
Fetuin-A is a mineral carrier protein: small angle neutron scattering provides new insight on Fetuin-A controlled calcification inhibition. Biophys J (2010) 0.97
The distribution of urinary calcium excretions in normal persons and stone-formers. Clin Chim Acta (1972) 0.97
Fetuin-A/albumin-mineral complexes resembling serum calcium granules and putative nanobacteria: demonstration of a dual inhibition-seeding concept. PLoS One (2009) 0.97
Bone and mineral metabolism and fibroblast growth factor 23 levels after kidney donation. Am J Kidney Dis (2011) 0.97
Expression of Klotho protein in the inner ear. Hear Res (2002) 0.96
Phosphate excess and progressive renal failure: the precipitation-calcification hypothesis. Kidney Int (1989) 0.93
Phosphorus additives in food and their effect in dialysis patients. Clin J Am Soc Nephrol (2009) 0.92
Mineral phases of calcium phosphate. Anat Rec (1989) 0.91
Clearance of fetuin-A--containing calciprotein particles is mediated by scavenger receptor-A. Circ Res (2012) 0.91
Phosphate-dependent stimulation of MGP and OPN expression in osteoblasts via the ERK1/2 pathway is modulated by calcium. Bone (2010) 0.89
Acute phosphate nephropathy-an emerging threat. Am J Med Sci (2008) 0.89
Effects of phosphate on vascular function under normal conditions and influence of the uraemic state. Cardiovasc Res (2012) 0.88
Promoter methylation confers kidney-specific expression of the Klotho gene. FASEB J (2012) 0.86
The new KDOQI clinical practice guidelines and clinical practice recommendations for diabetes and CKD. Blood Purif (2006) 0.84
Dietary phosphorus restriction in advanced chronic kidney disease: merits, challenges, and emerging strategies. Semin Dial (2010) 0.82
Impaired regulation of gonadotropins leads to the atrophy of the female reproductive system in klotho-deficient mice. Endocrinology (2005) 0.79
A micropuncture study of renal phosphate transport in rats with chronic renal failure and secondary hyperparathyroidism. J Clin Invest (1978) 0.79