Published in Proc Natl Acad Sci U S A on July 28, 2014
Potassium modulates electrolyte balance and blood pressure through effects on distal cell voltage and chloride. Cell Metab (2015) 1.59
The Effect of WNK4 on the Na+-Cl- Cotransporter Is Modulated by Intracellular Chloride. J Am Soc Nephrol (2014) 1.12
Dietary potassium and the renal control of salt balance and blood pressure. Pflugers Arch (2015) 0.91
Extracellular K(+) rapidly controls NaCl cotransporter phosphorylation in the native distal convoluted tubule by Cl(-) -dependent and independent mechanisms. J Physiol (2016) 0.89
Potassium and Its Discontents: New Insight, New Treatments. J Am Soc Nephrol (2015) 0.88
Revisiting the NaCl cotransporter regulation by with-no-lysine kinases. Am J Physiol Cell Physiol (2015) 0.87
Caveolin-1 Deficiency Inhibits the Basolateral K+ Channels in the Distal Convoluted Tubule and Impairs Renal K+ and Mg2+ Transport. J Am Soc Nephrol (2015) 0.87
KCNJ10 (Kir4.1) is expressed in the basolateral membrane of the cortical thick ascending limb. Am J Physiol Renal Physiol (2015) 0.86
Disruption of KCNJ10 (Kir4.1) stimulates the expression of ENaC in the collecting duct. Am J Physiol Renal Physiol (2016) 0.80
Vasopressin-induced stimulation of the Na(+)-activated K(+) channels is responsible for maintaining the basolateral K(+) conductance of the thick ascending limb (TAL) in EAST/SeSAME syndrome. Biochim Biophys Acta (2015) 0.80
New perspective of ClC-Kb/2 Cl- channel physiology in the distal renal tubule. Am J Physiol Renal Physiol (2016) 0.79
Renal tubular SGK1 deficiency causes impaired K+ excretion via loss of regulation of NEDD4-2/WNK1 and ENaC. Am J Physiol Renal Physiol (2016) 0.79
Role and mechanisms of regulation of the basolateral Kir 4.1/Kir 5.1 K(+) channels in the distal tubules. Acta Physiol (Oxf) (2016) 0.78
Two inwardly rectifying potassium channels, Irk1 and Irk2, play redundant roles in Drosophila renal tubule function. Am J Physiol Regul Integr Comp Physiol (2015) 0.77
The expression, regulation, and function of Kir4.1 (Kcnj10) in the mammalian kidney. Am J Physiol Renal Physiol (2016) 0.76
Potassium Homeostasis: The Knowns, the Unknowns, and the Health Benefits. Physiology (Bethesda) (2017) 0.76
The sodium chloride cotransporter (NCC) and epithelial sodium channel (ENaC) associate. Biochem J (2016) 0.76
Basolateral Kir4.1 activity in the distal convoluted tubule regulates K secretion by determining NaCl cotransporter activity. Curr Opin Nephrol Hypertens (2016) 0.75
CD8(+) T cells stimulate Na-Cl co-transporter NCC in distal convoluted tubules leading to salt-sensitive hypertension. Nat Commun (2017) 0.75
A Common Signal Patch Drives AP-1 Protein-dependent Golgi Export of Inwardly Rectifying Potassium Channels. J Biol Chem (2016) 0.75
In Primary Aldosteronism, Mineralocorticoids Influence Exosomal Sodium-Chloride Cotransporter Abundance. J Am Soc Nephrol (2016) 0.75
Potassium Sensing by Renal Distal Tubules Requires Kir4.1. J Am Soc Nephrol (2017) 0.75
WNK Kinases in Development and Disease. Curr Top Dev Biol (2016) 0.75
ENaC and ROMK activity are inhibited in the DCT2/CNT of TgWnk4(PHAII) mice. Am J Physiol Renal Physiol (2016) 0.75
Roles of renal ammonia metabolism other than in acid-base homeostasis. Pediatr Nephrol (2016) 0.75
Essential role of Kir5.1 channels in renal salt handling and blood pressure control. JCI Insight (2017) 0.75
Emerging Targets of Diuretic Therapy. Clin Pharmacol Ther (2017) 0.75
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Epilepsy, ataxia, sensorineural deafness, tubulopathy, and KCNJ10 mutations. N Engl J Med (2009) 4.96
Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities. Nature (2012) 4.26
WNK kinases regulate thiazide-sensitive Na-Cl cotransport. J Clin Invest (2003) 3.67
Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule. Nat Genet (2006) 3.57
Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1). J Biol Chem (2002) 2.87
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Seizures, sensorineural deafness, ataxia, mental retardation, and electrolyte imbalance (SeSAME syndrome) caused by mutations in KCNJ10. Proc Natl Acad Sci U S A (2009) 2.41
Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway. Proc Natl Acad Sci U S A (2009) 2.30
Kir4.1 potassium channel subunit is crucial for oligodendrocyte development and in vivo myelination. J Neurosci (2001) 2.23
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A SPAK isoform switch modulates renal salt transport and blood pressure. Cell Metab (2011) 1.79
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KCNJ10 gene mutations causing EAST syndrome (epilepsy, ataxia, sensorineural deafness, and tubulopathy) disrupt channel function. Proc Natl Acad Sci U S A (2010) 1.64
Collecting duct-specific gene inactivation of alphaENaC in the mouse kidney does not impair sodium and potassium balance. J Clin Invest (2003) 1.64
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Kir4.1/Kir5.1 channel forms the major K+ channel in the basolateral membrane of mouse renal collecting duct principal cells. Am J Physiol Renal Physiol (2008) 1.47
The salt-wasting phenotype of EAST syndrome, a disease with multifaceted symptoms linked to the KCNJ10 K+ channel. Pflugers Arch (2011) 1.23
Differential regulation of ROMK (Kir1.1) in distal nephron segments by dietary potassium. Am J Physiol Renal Physiol (2011) 1.23
Characterization of the thiazide-sensitive Na(+)-Cl(-) cotransporter: a new model for ions and diuretics interaction. Am J Physiol Renal Physiol (2000) 1.20
Localization of inward rectifier potassium channel Kir7.1 in the basolateral membrane of distal nephron and collecting duct. J Am Soc Nephrol (2000) 1.17
A new model of the distal convoluted tubule. Am J Physiol Renal Physiol (2012) 1.06
Renal phenotype in mice lacking the Kir5.1 (Kcnj16) K+ channel subunit contrasts with that observed in SeSAME/EAST syndrome. Proc Natl Acad Sci U S A (2011) 1.04
Renal expression of parvalbumin is critical for NaCl handling and response to diuretics. Proc Natl Acad Sci U S A (2007) 1.03
Molecular basis of decreased Kir4.1 function in SeSAME/EAST syndrome. J Am Soc Nephrol (2010) 1.01
Src family protein tyrosine kinase regulates the basolateral K channel in the distal convoluted tubule (DCT) by phosphorylation of KCNJ10 protein. J Biol Chem (2013) 1.01
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Mechanisms and regulation of renal magnesium transport. Annu Rev Physiol (2014) 0.82