Published in Am J Hematol on October 25, 2014
Ghrelin accelerates the growth and osteogenic differentiation of rabbit mesenchymal stem cells through the ERK1/2 pathway. BMC Biotechnol (2015) 0.76
Resveratrol Exerts Dosage-Dependent Effects on the Self-Renewal and Neural Differentiation of hUC-MSCs. Mol Cells (2016) 0.75
Comparison of Different Cytokine Conditions Reveals Resveratrol as a New Molecule for Ex Vivo Cultivation of Cord Blood-Derived Hematopoietic Stem Cells. Stem Cells Transl Med (2015) 0.75
SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell (2005) 24.00
Resveratrol improves health and survival of mice on a high-calorie diet. Nature (2006) 20.91
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell (2006) 19.16
A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Radiat Res (1961) 18.57
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature (2003) 17.52
Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov (2006) 11.77
Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science (1997) 10.90
Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature (2004) 10.36
Substrate-specific activation of sirtuins by resveratrol. J Biol Chem (2005) 5.28
Mechanism of human SIRT1 activation by resveratrol. J Biol Chem (2005) 4.86
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function. Cell Metab (2012) 3.69
Evidence for a common mechanism of SIRT1 regulation by allosteric activators. Science (2013) 3.40
Activation of p53 by SIRT1 inhibition enhances elimination of CML leukemia stem cells in combination with imatinib. Cancer Cell (2012) 2.96
SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization. Cell Stem Cell (2008) 2.67
Small molecule SIRT1 activators for the treatment of aging and age-related diseases. Trends Pharmacol Sci (2014) 2.37
Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells. J Biol Chem (2008) 1.95
Erythropoietin stimulates phosphorylation and activation of GATA-1 via the PI3-kinase/AKT signaling pathway. Blood (2005) 1.63
Activation of stress response gene SIRT1 by BCR-ABL promotes leukemogenesis. Blood (2011) 1.52
The daily oral administration of high doses of trans-resveratrol to rats for 28 days is not harmful. J Nutr (2002) 1.36
SIRT1 deficiency compromises mouse embryonic stem cell hematopoietic differentiation, and embryonic and adult hematopoiesis in the mouse. Blood (2010) 1.36
Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol. Blood (2010) 1.29
A molecular mechanism for direct sirtuin activation by resveratrol. PLoS One (2012) 1.26
ROS-mediated amplification of AKT/mTOR signalling pathway leads to myeloproliferative syndrome in Foxo3(-/-) mice. EMBO J (2010) 1.24
Resveratrol: from basic science to the clinic. Cell Cycle (2007) 1.23
Disparate in vitro and in vivo antileukemic effects of resveratrol, a natural polyphenolic compound found in grapes. J Nutr (2002) 1.19
Aging-like phenotype and defective lineage specification in SIRT1-deleted hematopoietic stem and progenitor cells. Stem Cell Reports (2014) 1.12
Resveratrol inhibits the growth and induces the apoptosis of both normal and leukemic hematopoietic cells. Carcinogenesis (2002) 1.11
Resveratrol ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice. Free Radic Biol Med (2012) 1.11
Dose-dependency of resveratrol in providing health benefits. Dose Response (2010) 1.11
Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance. J Exp Med (2013) 1.06
Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice. Haematologica (2013) 0.99
NAD-dependent histone deacetylase, SIRT1, plays essential roles in the maintenance of hematopoietic stem cells. Biochem Biophys Res Commun (2012) 0.95
Resveratrol selectively inhibits leukemia cells: a prospective agent for ex vivo bone marrow purging. Bone Marrow Transplant (2000) 0.90
Resveratrol, from experimental data to nutritional evidence: the emergence of a new food ingredient. Ann N Y Acad Sci (2013) 0.82
Development of human protein reference database as an initial platform for approaching systems biology in humans. Genome Res (2003) 14.79
Foxo3 is required for the regulation of oxidative stress in erythropoiesis. J Clin Invest (2007) 2.39
Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells. J Biol Chem (2008) 1.95
Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia. Nat Med (2013) 1.89
miR-451 protects against erythroid oxidant stress by repressing 14-3-3zeta. Genes Dev (2010) 1.80
FOXO1 is an essential regulator of pluripotency in human embryonic stem cells. Nat Cell Biol (2011) 1.70
Erythropoietin stimulates phosphorylation and activation of GATA-1 via the PI3-kinase/AKT signaling pathway. Blood (2005) 1.63
Oxidative stress regulation of stem and progenitor cells. Antioxid Redox Signal (2009) 1.38
ROS-mediated amplification of AKT/mTOR signalling pathway leads to myeloproliferative syndrome in Foxo3(-/-) mice. EMBO J (2010) 1.24
Structure of the Bcr-Abl oncoprotein oligomerization domain. Nat Struct Biol (2002) 1.24
Proteasome inhibition causes regression of leukemia and abrogates BCR-ABL-induced evasion of apoptosis in part through regulation of forkhead tumor suppressors. Cancer Res (2009) 1.14
Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice. Haematologica (2013) 0.99
Stra13 regulates oxidative stress mediated skeletal muscle degeneration. Hum Mol Genet (2009) 0.97
Regulation and function of FoxO transcription factors in normal and cancer stem cells: what have we learned? Curr Drug Targets (2011) 0.95
Stem cells, redox signaling, and stem cell aging. Antioxid Redox Signal (2014) 0.89
bHLH-Orange Transcription Factors in Development and Cancer. Transl Oncogenomics (2007) 0.89
Phosphotyrosine mapping in Bcr/Abl oncoprotein using phosphotyrosine-specific immonium ion scanning. Mol Cell Proteomics (2003) 0.85
FOXO3-mTOR metabolic cooperation in the regulation of erythroid cell maturation and homeostasis. Am J Hematol (2014) 0.85
[FoxO proteins in the control of stem cells]. Med Sci (Paris) (2012) 0.75